Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur Luyang GUAN |
Documents disponibles écrits par cet auteur (2)
Faire une suggestion Affiner la recherche
High definition transcranial direct current stimulation of the Cz improves social dysfunction in children with autism spectrum disorder: A randomized, sham, controlled study / Yonglu WANG in Autism Research, 16-10 (October 2023)
[article]
Titre : High definition transcranial direct current stimulation of the Cz improves social dysfunction in children with autism spectrum disorder: A randomized, sham, controlled study Type de document : Texte imprimé et/ou numérique Auteurs : Yonglu WANG, Auteur ; Fei WANG, Auteur ; Yue KONG, Auteur ; Tianshu GAO, Auteur ; Qingyao ZHU, Auteur ; Lu HAN, Auteur ; Bei SUN, Auteur ; Luyang GUAN, Auteur ; Ziyi ZHANG, Auteur ; Yuxin QIAN, Auteur ; Lingxi XU, Auteur ; Yun LI, Auteur ; Hui FANG, Auteur ; Gongkai JIAO, Auteur ; Xiaoyan KE, Auteur Article en page(s) : p.2035-2048 Index. décimale : PER Périodiques Résumé : Abstract The purpose of this study was to determine the effect of the Cz of high-definition 5-channel tDCS (HD-tDCS) on social function in 4-12 years-old children with autism spectrum disorder (ASD). This study was a randomized, double-blind, pseudo-controlled trial in which 45 ASD children were recruited and divided into three groups with sex, age, and rehabilitation treatment as control variables. Each group of 15 children with ASD was randomly administered active HD-tDCS with the Cz as the central anode, active HD-tDCS with the left dorsolateral prefrontal cortex (F3) as the central anode, and sham HD-tDCS with the Cz as the central anode with 14 daily sessions in 3?weeks. The Social Responsiveness Scale Chinese Version (SRS-Chinese Version) was compared 1?week after stimulation with values recorded 1?week prior to stimulation. At the end of treatment, both the anodal Cz and anodal left DLFPC tDCS decreased the measures of SRS-Chinese Version. The total score of SRS-Chinese Version decreased by 13.08%, social cognition decreased by 18.33%, and social communication decreased by 10.79%, which were significantly improved over the Cz central anode active stimulation group, especially in children with young age, and middle and low function. There was no significant change in the total score and subscale score of SRS-Chinese Version over the Cz central anode sham stimulation group. In the F3 central anode active stimulation group, the total score of SRS-Chinese Version decreased by 13%, autistic behavior decreased by 19.39%, and social communication decreased by 14.39%, which were all significantly improved. However, there was no significant difference in effect between the Cz and left DLPFC stimulation conditions. HD-tDCS of the Cz central anode may be an effective treatment for social dysfunction in children with ASD. En ligne : https://doi.org/10.1002/aur.3018 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=513
in Autism Research > 16-10 (October 2023) . - p.2035-2048[article] High definition transcranial direct current stimulation of the Cz improves social dysfunction in children with autism spectrum disorder: A randomized, sham, controlled study [Texte imprimé et/ou numérique] / Yonglu WANG, Auteur ; Fei WANG, Auteur ; Yue KONG, Auteur ; Tianshu GAO, Auteur ; Qingyao ZHU, Auteur ; Lu HAN, Auteur ; Bei SUN, Auteur ; Luyang GUAN, Auteur ; Ziyi ZHANG, Auteur ; Yuxin QIAN, Auteur ; Lingxi XU, Auteur ; Yun LI, Auteur ; Hui FANG, Auteur ; Gongkai JIAO, Auteur ; Xiaoyan KE, Auteur . - p.2035-2048.
in Autism Research > 16-10 (October 2023) . - p.2035-2048
Index. décimale : PER Périodiques Résumé : Abstract The purpose of this study was to determine the effect of the Cz of high-definition 5-channel tDCS (HD-tDCS) on social function in 4-12 years-old children with autism spectrum disorder (ASD). This study was a randomized, double-blind, pseudo-controlled trial in which 45 ASD children were recruited and divided into three groups with sex, age, and rehabilitation treatment as control variables. Each group of 15 children with ASD was randomly administered active HD-tDCS with the Cz as the central anode, active HD-tDCS with the left dorsolateral prefrontal cortex (F3) as the central anode, and sham HD-tDCS with the Cz as the central anode with 14 daily sessions in 3?weeks. The Social Responsiveness Scale Chinese Version (SRS-Chinese Version) was compared 1?week after stimulation with values recorded 1?week prior to stimulation. At the end of treatment, both the anodal Cz and anodal left DLFPC tDCS decreased the measures of SRS-Chinese Version. The total score of SRS-Chinese Version decreased by 13.08%, social cognition decreased by 18.33%, and social communication decreased by 10.79%, which were significantly improved over the Cz central anode active stimulation group, especially in children with young age, and middle and low function. There was no significant change in the total score and subscale score of SRS-Chinese Version over the Cz central anode sham stimulation group. In the F3 central anode active stimulation group, the total score of SRS-Chinese Version decreased by 13%, autistic behavior decreased by 19.39%, and social communication decreased by 14.39%, which were all significantly improved. However, there was no significant difference in effect between the Cz and left DLPFC stimulation conditions. HD-tDCS of the Cz central anode may be an effective treatment for social dysfunction in children with ASD. En ligne : https://doi.org/10.1002/aur.3018 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=513 Risk factors and clinical characteristics of autism spectrum disorder with regression in China / Lu HAN in Autism Research, 16-9 (September 2023)
[article]
Titre : Risk factors and clinical characteristics of autism spectrum disorder with regression in China Type de document : Texte imprimé et/ou numérique Auteurs : Lu HAN, Auteur ; Luyang GUAN, Auteur ; Ziyi ZHANG, Auteur ; Wenqing LI, Auteur ; Jinhui LI, Auteur ; Chenxi BAO, Auteur ; Mei YE, Auteur ; Min TANG, Auteur ; Xiaoyan KE, Auteur Article en page(s) : p.1836-1846 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Autism spectrum disorder with regression (ASD-R) is characterized by the loss of previously acquired skills during the initial year of life. This study aimed to investigate the clinical characteristics, patterns of regression, and potential risk factors associated with ASD-R in the Chinese Han population. A case-control study was conducted between September 2020 and March 2022. A total of 186 children were enrolled, including 58 children with ASD-R, 70 with ASD without regression (ASD-NR), and 58 typically developing children. Demographic information, clinical characteristics, and potential risk factors related to ASD-R were assessed using a combination of questionnaires, interviews, and physician assessments. The results revealed that children with ASD-R exhibited more severe impairments in social communication and stereotyped behaviors compared with those with ASD-NR. Language regression, constituting 40% of cases within the ASD-R group, was found to be the most common type of regression. Furthermore, our analysis revealed that fever (OR=4.01, 95% CI: 1.26-12.76) and diarrhea (OR=6.32, 95% CI: 1.38-29.03) were identified as significant risk factors for ASD-R. These findings contribute to our understanding of the heterogeneity of ASD and highlight the importance of considering immune responses and gastrointestinal factors in the etiology of ASD-R. En ligne : https://doi.org/10.1002/aur.3008 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510
in Autism Research > 16-9 (September 2023) . - p.1836-1846[article] Risk factors and clinical characteristics of autism spectrum disorder with regression in China [Texte imprimé et/ou numérique] / Lu HAN, Auteur ; Luyang GUAN, Auteur ; Ziyi ZHANG, Auteur ; Wenqing LI, Auteur ; Jinhui LI, Auteur ; Chenxi BAO, Auteur ; Mei YE, Auteur ; Min TANG, Auteur ; Xiaoyan KE, Auteur . - p.1836-1846.
Langues : Anglais (eng)
in Autism Research > 16-9 (September 2023) . - p.1836-1846
Index. décimale : PER Périodiques Résumé : Abstract Autism spectrum disorder with regression (ASD-R) is characterized by the loss of previously acquired skills during the initial year of life. This study aimed to investigate the clinical characteristics, patterns of regression, and potential risk factors associated with ASD-R in the Chinese Han population. A case-control study was conducted between September 2020 and March 2022. A total of 186 children were enrolled, including 58 children with ASD-R, 70 with ASD without regression (ASD-NR), and 58 typically developing children. Demographic information, clinical characteristics, and potential risk factors related to ASD-R were assessed using a combination of questionnaires, interviews, and physician assessments. The results revealed that children with ASD-R exhibited more severe impairments in social communication and stereotyped behaviors compared with those with ASD-NR. Language regression, constituting 40% of cases within the ASD-R group, was found to be the most common type of regression. Furthermore, our analysis revealed that fever (OR=4.01, 95% CI: 1.26-12.76) and diarrhea (OR=6.32, 95% CI: 1.38-29.03) were identified as significant risk factors for ASD-R. These findings contribute to our understanding of the heterogeneity of ASD and highlight the importance of considering immune responses and gastrointestinal factors in the etiology of ASD-R. En ligne : https://doi.org/10.1002/aur.3008 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510