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Auteur Niloofar FARAJI |
Documents disponibles écrits par cet auteur (1)
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Single-locus and Haplotype Associations of GRIN2B Gene with Autism Spectrum Disorders and the Demographic and Clinical Characteristics of Patients in Guilan, Iran / Niloofar FARAJI ; Sajjad REZAEI ; Parvaneh KESHAVARZ in Journal of Autism and Developmental Disorders, 54-2 (February 2024)
[article]
Titre : Single-locus and Haplotype Associations of GRIN2B Gene with Autism Spectrum Disorders and the Demographic and Clinical Characteristics of Patients in Guilan, Iran Type de document : Texte imprimé et/ou numérique Auteurs : Niloofar FARAJI, Auteur ; Sajjad REZAEI, Auteur ; Parvaneh KESHAVARZ, Auteur Article en page(s) : p.607-614 Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASDs) are described as generalized developmental disorders, with an average age of onset of 36 months. Genetic and environmental factors may contribute to this multifactorial disorder. The present study aimed to investigate the association of three GRIN2B polymorphisms, including rs1019385, rs1024893, and rs3764028, with ASDs. Based on the results, there was a significant difference regarding the genotype frequency of rs3764028 polymorphism between the control and case (ASD) groups (P?=?0.027). According to the recessive model, this variant was associated with ASDs (P?=?0.23). None of the eight haplotype models with frequencies above 0.5 showed significant differences between the case and control groups in terms of allelic frequency. The present results showed that the rs376028 variant was directly related to the phenotypic symptoms of ASDs. En ligne : https://doi.org/10.1007/s10803-022-05818-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=520
in Journal of Autism and Developmental Disorders > 54-2 (February 2024) . - p.607-614[article] Single-locus and Haplotype Associations of GRIN2B Gene with Autism Spectrum Disorders and the Demographic and Clinical Characteristics of Patients in Guilan, Iran [Texte imprimé et/ou numérique] / Niloofar FARAJI, Auteur ; Sajjad REZAEI, Auteur ; Parvaneh KESHAVARZ, Auteur . - p.607-614.
in Journal of Autism and Developmental Disorders > 54-2 (February 2024) . - p.607-614
Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASDs) are described as generalized developmental disorders, with an average age of onset of 36 months. Genetic and environmental factors may contribute to this multifactorial disorder. The present study aimed to investigate the association of three GRIN2B polymorphisms, including rs1019385, rs1024893, and rs3764028, with ASDs. Based on the results, there was a significant difference regarding the genotype frequency of rs3764028 polymorphism between the control and case (ASD) groups (P?=?0.027). According to the recessive model, this variant was associated with ASDs (P?=?0.23). None of the eight haplotype models with frequencies above 0.5 showed significant differences between the case and control groups in terms of allelic frequency. The present results showed that the rs376028 variant was directly related to the phenotypic symptoms of ASDs. En ligne : https://doi.org/10.1007/s10803-022-05818-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=520