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Personal reflections on observational and experimental research approaches to childhood psychopathology / Judith RAPOPORT in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)
[article]
Titre : Personal reflections on observational and experimental research approaches to childhood psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : Judith RAPOPORT, Auteur Année de publication : 2009 Article en page(s) : p.36-43 Langues : Anglais (eng) Mots-clés : Attention-deficit-hyperactivity-disorder child-psychiatry childhood-onset-schizophrenia epidemiology experimental-research follow-up-studies observational-research obsessive-compulsive-disorder pervasive-developmental-disorder stimulants Index. décimale : PER Périodiques Résumé : The past 50 years have seen dramatic changes in childhood psychopathology research. The goal of this overview is to contrast observational and experimental research approaches; both have grown more complex such that the boundary between these approaches may be blurred. Both are essential. Landmark observational studies with long-term follow-up (Robins, 1966; Yarrow, Campbell, & Burton, 1970) have had – and continue to have – unique impact on clinical research and practice. Epidemiological studies showed high rates of psychological disorder and their close tie to neurological impairment (Rutter, Tizard, & Whitemore, 1970). These studies have current impact with respect to brain imaging correlates of clinical outcome. Pharmacological studies, particularly those on stimulants and on treatment of pediatric obsessive compulsive disorder (OCD), have propelled experimental methodology and inspired translational approaches. Predicted future trends are: more informed subgrouping of our heterogeneous phenotypes, reliance on multicenter trials, and documentation of non-conventional methods of care delivery. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01975.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693
in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.36-43[article] Personal reflections on observational and experimental research approaches to childhood psychopathology [Texte imprimé et/ou numérique] / Judith RAPOPORT, Auteur . - 2009 . - p.36-43.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.36-43
Mots-clés : Attention-deficit-hyperactivity-disorder child-psychiatry childhood-onset-schizophrenia epidemiology experimental-research follow-up-studies observational-research obsessive-compulsive-disorder pervasive-developmental-disorder stimulants Index. décimale : PER Périodiques Résumé : The past 50 years have seen dramatic changes in childhood psychopathology research. The goal of this overview is to contrast observational and experimental research approaches; both have grown more complex such that the boundary between these approaches may be blurred. Both are essential. Landmark observational studies with long-term follow-up (Robins, 1966; Yarrow, Campbell, & Burton, 1970) have had – and continue to have – unique impact on clinical research and practice. Epidemiological studies showed high rates of psychological disorder and their close tie to neurological impairment (Rutter, Tizard, & Whitemore, 1970). These studies have current impact with respect to brain imaging correlates of clinical outcome. Pharmacological studies, particularly those on stimulants and on treatment of pediatric obsessive compulsive disorder (OCD), have propelled experimental methodology and inspired translational approaches. Predicted future trends are: more informed subgrouping of our heterogeneous phenotypes, reliance on multicenter trials, and documentation of non-conventional methods of care delivery. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01975.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693