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Auteur Nancy J. MINSHEW |
Documents disponibles écrits par cet auteur (51)
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A comparison of measures for assessing the level and nature of intelligence in verbal children and adults with autism spectrum disorder / Kimberly E. BODNER in Research in Autism Spectrum Disorders, 8-11 (November 2014)
[article]
Titre : A comparison of measures for assessing the level and nature of intelligence in verbal children and adults with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Kimberly E. BODNER, Auteur ; Diane L. WILLIAMS, Auteur ; Christopher R. ENGELHARDT, Auteur ; Nancy J. MINSHEW, Auteur Article en page(s) : p.1434-1442 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder High-functioning Intelligence Wechsler Raven's Progressive Matrices Cognition Index. décimale : PER Périodiques Résumé : Previous work has suggested that the Raven's Progressive Matrices (RPM) are better suited for capturing the nature of intelligence for individuals with autism spectrum disorder (ASD) than the Wechsler scales. The RPM measures ‘fluid intelligence’, an area for which it has been argued that persons with ASD have a relative strength. Given that measures of intelligence are used for establishing clinical diagnoses, for making educational decisions, and for group-matching in research studies, continued examination of this contention is warranted. In the current study, verbal children with ASD performed moderately better on the RPM than on the Wechsler scales; children without ASD received higher percentile scores on the Wechsler than on the RPM. Adults with and without ASD received higher percentile scores on the Wechsler than the RPM. Results suggest that the RPM and Wechsler scales measure different aspects of cognitive abilities in verbal individuals with ASD. For the verbal children and adults with ASD in the current study, the RPM and Wechsler scales have unique contributions that must be considered in context when establishing a baseline of cognitive function. The results of this investigation highlight the importance of thoughtfully selecting appropriate measures of intelligence consistent with clinical, educational, and research purposes, especially for verbal children and adults with ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.07.015 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241
in Research in Autism Spectrum Disorders > 8-11 (November 2014) . - p.1434-1442[article] A comparison of measures for assessing the level and nature of intelligence in verbal children and adults with autism spectrum disorder [Texte imprimé et/ou numérique] / Kimberly E. BODNER, Auteur ; Diane L. WILLIAMS, Auteur ; Christopher R. ENGELHARDT, Auteur ; Nancy J. MINSHEW, Auteur . - p.1434-1442.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 8-11 (November 2014) . - p.1434-1442
Mots-clés : Autism spectrum disorder High-functioning Intelligence Wechsler Raven's Progressive Matrices Cognition Index. décimale : PER Périodiques Résumé : Previous work has suggested that the Raven's Progressive Matrices (RPM) are better suited for capturing the nature of intelligence for individuals with autism spectrum disorder (ASD) than the Wechsler scales. The RPM measures ‘fluid intelligence’, an area for which it has been argued that persons with ASD have a relative strength. Given that measures of intelligence are used for establishing clinical diagnoses, for making educational decisions, and for group-matching in research studies, continued examination of this contention is warranted. In the current study, verbal children with ASD performed moderately better on the RPM than on the Wechsler scales; children without ASD received higher percentile scores on the Wechsler than on the RPM. Adults with and without ASD received higher percentile scores on the Wechsler than the RPM. Results suggest that the RPM and Wechsler scales measure different aspects of cognitive abilities in verbal individuals with ASD. For the verbal children and adults with ASD in the current study, the RPM and Wechsler scales have unique contributions that must be considered in context when establishing a baseline of cognitive function. The results of this investigation highlight the importance of thoughtfully selecting appropriate measures of intelligence consistent with clinical, educational, and research purposes, especially for verbal children and adults with ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.07.015 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 Corpus Callosum Volume and Neurocognition in Autism / Christopher J. KEARY in Journal of Autism and Developmental Disorders, 39-6 (June 2009)
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Titre : Corpus Callosum Volume and Neurocognition in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Christopher J. KEARY, Auteur ; Nancy J. MINSHEW, Auteur ; Antonio Y. HARDAN, Auteur ; Matcheri S. KESHAVAN, Auteur ; Rahul BANSAL, Auteur ; Dhruman GORADIA, Auteur ; Serguei FEDOROV, Auteur Année de publication : 2009 Article en page(s) : p.834-841 Langues : Anglais (eng) Mots-clés : Autism Corpus-callosum Volume MRI Connectivity Neuropsychological-tests Index. décimale : PER Périodiques Résumé : The corpus callosum has recently been considered as an index of interhemispheric connectivity. This study applied a novel volumetric method to examine the size of the corpus callosum in 32 individuals with autism and 34 age-, gender- and IQ-matched controls and to investigate the relationship between this structure and cognitive measures linked to interhemispheric functioning. Participants with autism displayed reductions in total corpus callosum volume and in several of its subdivisions. Relationships were also observed between volumetric alterations and performance on several cognitive tests including the Tower of Hanoi test. These findings provide further evidence for anatomical alterations in the corpus callosum in autism, but warrant additional studies examining the relationship of this structure and specific measures of interhemispheric connectivity. En ligne : http://dx.doi.org/10.1007/s10803-009-0689-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=758
in Journal of Autism and Developmental Disorders > 39-6 (June 2009) . - p.834-841[article] Corpus Callosum Volume and Neurocognition in Autism [Texte imprimé et/ou numérique] / Christopher J. KEARY, Auteur ; Nancy J. MINSHEW, Auteur ; Antonio Y. HARDAN, Auteur ; Matcheri S. KESHAVAN, Auteur ; Rahul BANSAL, Auteur ; Dhruman GORADIA, Auteur ; Serguei FEDOROV, Auteur . - 2009 . - p.834-841.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 39-6 (June 2009) . - p.834-841
Mots-clés : Autism Corpus-callosum Volume MRI Connectivity Neuropsychological-tests Index. décimale : PER Périodiques Résumé : The corpus callosum has recently been considered as an index of interhemispheric connectivity. This study applied a novel volumetric method to examine the size of the corpus callosum in 32 individuals with autism and 34 age-, gender- and IQ-matched controls and to investigate the relationship between this structure and cognitive measures linked to interhemispheric functioning. Participants with autism displayed reductions in total corpus callosum volume and in several of its subdivisions. Relationships were also observed between volumetric alterations and performance on several cognitive tests including the Tower of Hanoi test. These findings provide further evidence for anatomical alterations in the corpus callosum in autism, but warrant additional studies examining the relationship of this structure and specific measures of interhemispheric connectivity. En ligne : http://dx.doi.org/10.1007/s10803-009-0689-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=758 Correlates of social functioning in autism spectrum disorder: The role of social cognition / Lauren BISHOP-FITZPATRICK in Research in Autism Spectrum Disorders, 35 (March 2017)
[article]
Titre : Correlates of social functioning in autism spectrum disorder: The role of social cognition Type de document : Texte imprimé et/ou numérique Auteurs : Lauren BISHOP-FITZPATRICK, Auteur ; Carla A. MAZEFSKY, Auteur ; Shaun M. EACK, Auteur ; Nancy J. MINSHEW, Auteur Article en page(s) : p.25-34 Langues : Anglais (eng) Mots-clés : Theory of mind Motor function Second-order false belief Adaptive behavior Social impairment Manipulative dexterity Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) experience marked challenges with social function by definition, but few modifiable predictors of social functioning in ASD have been identified in extant research. This study hypothesized that deficits in social cognition and motor function may help to explain poor social functioning in individuals with ASD. Method Cross-sectional data from 108 individuals with ASD and without intellectual disability ages 9 through 27.5 were used to assess the relationship between social cognition and motor function, and social functioning. Results Results of hierarchical multiple regression analyses revealed that greater social cognition, but not motor function, was significantly associated with better social functioning when controlling for sex, age, and intelligence quotient. Post-hoc analyses revealed that better performance on second-order false belief tasks was associated with higher levels of socially adaptive behavior and lower levels of social problems. Our findings support the development and testing of interventions that target social cognition in order to improve social functioning in individuals with ASD. Interventions that teach generalizable skills to help people with ASD better understand social situations and develop competency in advanced perspective taking have the potential to create more durable change because their effects can be applied to a wide and varied set of situations and not simply a prescribed set of rehearsed situations. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.11.013 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=304
in Research in Autism Spectrum Disorders > 35 (March 2017) . - p.25-34[article] Correlates of social functioning in autism spectrum disorder: The role of social cognition [Texte imprimé et/ou numérique] / Lauren BISHOP-FITZPATRICK, Auteur ; Carla A. MAZEFSKY, Auteur ; Shaun M. EACK, Auteur ; Nancy J. MINSHEW, Auteur . - p.25-34.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 35 (March 2017) . - p.25-34
Mots-clés : Theory of mind Motor function Second-order false belief Adaptive behavior Social impairment Manipulative dexterity Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) experience marked challenges with social function by definition, but few modifiable predictors of social functioning in ASD have been identified in extant research. This study hypothesized that deficits in social cognition and motor function may help to explain poor social functioning in individuals with ASD. Method Cross-sectional data from 108 individuals with ASD and without intellectual disability ages 9 through 27.5 were used to assess the relationship between social cognition and motor function, and social functioning. Results Results of hierarchical multiple regression analyses revealed that greater social cognition, but not motor function, was significantly associated with better social functioning when controlling for sex, age, and intelligence quotient. Post-hoc analyses revealed that better performance on second-order false belief tasks was associated with higher levels of socially adaptive behavior and lower levels of social problems. Our findings support the development and testing of interventions that target social cognition in order to improve social functioning in individuals with ASD. Interventions that teach generalizable skills to help people with ASD better understand social situations and develop competency in advanced perspective taking have the potential to create more durable change because their effects can be applied to a wide and varied set of situations and not simply a prescribed set of rehearsed situations. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.11.013 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=304 Cortical patterns of category-selective activation for faces, places and objects in adults with autism / Kate HUMPHREYS in Autism Research, 1-1 (February 2008)
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Titre : Cortical patterns of category-selective activation for faces, places and objects in adults with autism Type de document : Texte imprimé et/ou numérique Auteurs : Kate HUMPHREYS, Auteur ; Nancy J. MINSHEW, Auteur ; Marlene BEHRMANN, Auteur ; Uri HASSON, Auteur ; Galia AVIDAN, Auteur Année de publication : 2008 Article en page(s) : p.52-63 Langues : Anglais (eng) Mots-clés : high-functioning-autism fMRI object-perception occipito-temporal-cortex visual-system Index. décimale : PER Périodiques Résumé : Autism is associated with widespread atypicalities in perception, cognition and social behavior. A crucial question concerns how these atypicalities are reflected in the underlying brain activation. One way to examine possible perturbations of cortical organization in autism is to analyze the activation of category-selective ventral visual cortex, already clearly delineated in typical populations. We mapped out the neural correlates of face, place and common object processing, using functional magnetic resonance imaging (fMRI), in a group of high-functioning adults with autism and a typical comparison group, under both controlled and more naturalistic, viewing conditions. There were no consistent group differences in place-related regions. Although there were no significant differences in the extent of the object-related regions, there was more variability for these regions in the autism group. The most marked group differences were in face-selective cortex, with individuals with autism evincing reduced activation, not only in fusiform face area but also in superior temporal sulcus and occipital face area. Ventral visual cortex appears to be organized differently in high-functioning adults with autism, at least for face-selective regions, although subtle differences may also exist for other categories. We propose that cascading developmental effects of low-level differences in neuronal connectivity result in a much more pronounced effect on later developing cortical systems, such as that for face-processing, than earlier maturing systems (those for objects and places). En ligne : http://dx.doi.org/10.1002/aur.1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=929
in Autism Research > 1-1 (February 2008) . - p.52-63[article] Cortical patterns of category-selective activation for faces, places and objects in adults with autism [Texte imprimé et/ou numérique] / Kate HUMPHREYS, Auteur ; Nancy J. MINSHEW, Auteur ; Marlene BEHRMANN, Auteur ; Uri HASSON, Auteur ; Galia AVIDAN, Auteur . - 2008 . - p.52-63.
Langues : Anglais (eng)
in Autism Research > 1-1 (February 2008) . - p.52-63
Mots-clés : high-functioning-autism fMRI object-perception occipito-temporal-cortex visual-system Index. décimale : PER Périodiques Résumé : Autism is associated with widespread atypicalities in perception, cognition and social behavior. A crucial question concerns how these atypicalities are reflected in the underlying brain activation. One way to examine possible perturbations of cortical organization in autism is to analyze the activation of category-selective ventral visual cortex, already clearly delineated in typical populations. We mapped out the neural correlates of face, place and common object processing, using functional magnetic resonance imaging (fMRI), in a group of high-functioning adults with autism and a typical comparison group, under both controlled and more naturalistic, viewing conditions. There were no consistent group differences in place-related regions. Although there were no significant differences in the extent of the object-related regions, there was more variability for these regions in the autism group. The most marked group differences were in face-selective cortex, with individuals with autism evincing reduced activation, not only in fusiform face area but also in superior temporal sulcus and occipital face area. Ventral visual cortex appears to be organized differently in high-functioning adults with autism, at least for face-selective regions, although subtle differences may also exist for other categories. We propose that cascading developmental effects of low-level differences in neuronal connectivity result in a much more pronounced effect on later developing cortical systems, such as that for face-processing, than earlier maturing systems (those for objects and places). En ligne : http://dx.doi.org/10.1002/aur.1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=929 Cortical underconnectivity coupled with preserved visuospatial cognition in autism: Evidence from an fMRI study of an embedded figures task / Saudamini Roy DAMARLA in Autism Research, 3-5 (October 2010)
[article]
Titre : Cortical underconnectivity coupled with preserved visuospatial cognition in autism: Evidence from an fMRI study of an embedded figures task Type de document : Texte imprimé et/ou numérique Auteurs : Saudamini Roy DAMARLA, Auteur ; Timothy A. KELLER, Auteur ; Rajesh K. KANA, Auteur ; Vladimir L. CHERKASSKY, Auteur ; Diane L. WILLIAMS, Auteur ; Nancy J. MINSHEW, Auteur ; Marcel Adam JUST, Auteur Année de publication : 2010 Article en page(s) : p.273-279 Langues : Anglais (eng) Mots-clés : embedded figures task functional connectivity corpus callosum functional MRI Index. décimale : PER Périodiques Résumé : Individuals with high-functioning autism sometimes exhibit intact or superior performance on visuospatial tasks, in contrast to impaired functioning in other domains such as language comprehension, executive tasks, and social functions. The goal of the current study was to investigate the neural bases of preserved visuospatial processing in high-functioning autism from the perspective of the cortical underconnectivity theory. We used a combination of behavioral, functional magnetic resonance imaging, functional connectivity, and corpus callosum morphometric methodological tools. Thirteen participants with high-functioning autism and 13 controls (age-, IQ-, and gender-matched) were scanned while performing an Embedded Figures Task. Despite the ability of the autism group to attain behavioral performance comparable to the control group, the brain imaging results revealed several group differences consistent with the cortical underconnectivity account of autism. First, relative to controls, the autism group showed less activation in the left dorsolateral prefrontal and inferior parietal areas and more activation in visuospatial (bilateral superior parietal extending to inferior parietal and right occipital) areas. Second, the autism group demonstrated lower functional connectivity between higher-order working memory/executive areas and visuospatial regions (between frontal and parietal-occipital). Third, the size of the corpus callosum (an index of anatomical connectivity) was positively correlated with frontal–posterior (parietal and occipital) functional connectivity in the autism group. Thus, even in the visuospatial domain, where preserved performance among people with autism is observed, the neuroimaging signatures of cortical underconnectivity persist. En ligne : http://dx.doi.org/10.1002/aur.153 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=115
in Autism Research > 3-5 (October 2010) . - p.273-279[article] Cortical underconnectivity coupled with preserved visuospatial cognition in autism: Evidence from an fMRI study of an embedded figures task [Texte imprimé et/ou numérique] / Saudamini Roy DAMARLA, Auteur ; Timothy A. KELLER, Auteur ; Rajesh K. KANA, Auteur ; Vladimir L. CHERKASSKY, Auteur ; Diane L. WILLIAMS, Auteur ; Nancy J. MINSHEW, Auteur ; Marcel Adam JUST, Auteur . - 2010 . - p.273-279.
Langues : Anglais (eng)
in Autism Research > 3-5 (October 2010) . - p.273-279
Mots-clés : embedded figures task functional connectivity corpus callosum functional MRI Index. décimale : PER Périodiques Résumé : Individuals with high-functioning autism sometimes exhibit intact or superior performance on visuospatial tasks, in contrast to impaired functioning in other domains such as language comprehension, executive tasks, and social functions. The goal of the current study was to investigate the neural bases of preserved visuospatial processing in high-functioning autism from the perspective of the cortical underconnectivity theory. We used a combination of behavioral, functional magnetic resonance imaging, functional connectivity, and corpus callosum morphometric methodological tools. Thirteen participants with high-functioning autism and 13 controls (age-, IQ-, and gender-matched) were scanned while performing an Embedded Figures Task. Despite the ability of the autism group to attain behavioral performance comparable to the control group, the brain imaging results revealed several group differences consistent with the cortical underconnectivity account of autism. First, relative to controls, the autism group showed less activation in the left dorsolateral prefrontal and inferior parietal areas and more activation in visuospatial (bilateral superior parietal extending to inferior parietal and right occipital) areas. Second, the autism group demonstrated lower functional connectivity between higher-order working memory/executive areas and visuospatial regions (between frontal and parietal-occipital). Third, the size of the corpus callosum (an index of anatomical connectivity) was positively correlated with frontal–posterior (parietal and occipital) functional connectivity in the autism group. Thus, even in the visuospatial domain, where preserved performance among people with autism is observed, the neuroimaging signatures of cortical underconnectivity persist. En ligne : http://dx.doi.org/10.1002/aur.153 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=115 Deficits in adults with autism spectrum disorders when processing multiple objects in dynamic scenes / Kirsten O'HEARN in Autism Research, 4-2 (April 2011)
PermalinkEmotion Regulation Patterns in Adolescents With High-Functioning Autism Spectrum Disorder: Comparison to Typically Developing Adolescents and Association With Psychiatric Symptoms / Carla A. MAZEFSKY in Autism Research, 7-3 (June 2014)
PermalinkEndogenous Spatial Attention: Evidence for Intact Functioning in Adults With Autism / Michael A. GRUBB in Autism Research, 6-2 (April 2013)
PermalinkFurther understanding of complex information processing in verbal adolescents and adults with autism spectrum disorders / Diane L. WILLIAMS in Autism, 19-7 (October 2015)
PermalinkGender discrimination of eyes and mouths by individuals with autism / Catherine A. BEST in Autism Research, 3-2 (April 2010)
PermalinkInformation Processing, Neural Connectivity, and Neuronal Organization / Nancy J. MINSHEW
PermalinkIs the Structure of the Brain of Individuals With ASC Different? / Nancy J. MINSHEW
PermalinkA Lack of Left Visual Field Bias When Individuals with Autism Process Faces / Eva M. DUNDAS in Journal of Autism and Developmental Disorders, 42-6 (June 2012)
PermalinkLocal vs. global approaches to reproducing the Rey Osterrieth complex figure by children, adolescents, and adults with high-functioning autism / Emily S. KUSCHNER in Autism Research, 2-6 (December 2009)
PermalinkLong-term memory in older children/adolescents and adults with autism spectrum disorder / Nancy J. MINSHEW ; Gerald GOLDSTEIN ; Carla A. MAZEFSKY in Autism Research, 10-9 (September 2017)
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