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Auteur Michael G. AMAN |
Documents disponibles écrits par cet auteur (31)
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Sensitivity of the modified Children’s Yale–Brown Obsessive Compulsive Scale to detect change: Results from two multi-site trials / Lawrence SCAHILL in Autism, 20-2 (February 2016)
[article]
Titre : Sensitivity of the modified Children’s Yale–Brown Obsessive Compulsive Scale to detect change: Results from two multi-site trials Type de document : Texte imprimé et/ou numérique Auteurs : Lawrence SCAHILL, Auteur ; Denis G SUKHODOLSKY, Auteur ; Emily I. ANDERBERG, Auteur ; Anastasia DIMITROPOULOS, Auteur ; James DZIURA, Auteur ; Michael G. AMAN, Auteur ; James MCCRACKEN, Auteur ; Elaine TIERNEY, Auteur ; Victoria HALLETT, Auteur ; Karol KATZ, Auteur ; Benedetto VITIELLO, Auteur ; Christopher MCDOUGLE, Auteur Article en page(s) : p.145-152 Langues : Anglais (eng) Mots-clés : autism spectrum disorder clinical trials outcome measurement repetitive behavior risperidone Index. décimale : PER Périodiques Résumé : Repetitive behavior is a core feature of autism spectrum disorder. We used 8-week data from two federally funded, multi-site, randomized trials with risperidone conducted by the Research Units on Pediatric Psychopharmacology Autism Network to evaluate the sensitivity of the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder to detect change with treatment. Study 1 included 52 subjects assigned to placebo and 49 subjects to risperidone under double-blind conditions. In Study 2, 49 subjects received risperidone only and 75 subjects received risperidone plus parent training. The combined sample consisted of 187 boys and 38 girls (aged 4–17?years). At the medication-free baseline, the internal consistency on the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder total score was excellent (Cronbach’s alpha = 0.84) and the mean scores were similar across the four groups. Compared to placebo in Study 1, all three active treatment groups showed significant improvement (effect sizes: 0.74–0.88). There were no differences between active treatment groups. These results indicate that the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder has acceptable test–retest as evidenced by the medium to high correlations in the placebo group and demonstrated sensitivity to change with treatment. En ligne : http://dx.doi.org/10.1177/1362361315574889 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278
in Autism > 20-2 (February 2016) . - p.145-152[article] Sensitivity of the modified Children’s Yale–Brown Obsessive Compulsive Scale to detect change: Results from two multi-site trials [Texte imprimé et/ou numérique] / Lawrence SCAHILL, Auteur ; Denis G SUKHODOLSKY, Auteur ; Emily I. ANDERBERG, Auteur ; Anastasia DIMITROPOULOS, Auteur ; James DZIURA, Auteur ; Michael G. AMAN, Auteur ; James MCCRACKEN, Auteur ; Elaine TIERNEY, Auteur ; Victoria HALLETT, Auteur ; Karol KATZ, Auteur ; Benedetto VITIELLO, Auteur ; Christopher MCDOUGLE, Auteur . - p.145-152.
Langues : Anglais (eng)
in Autism > 20-2 (February 2016) . - p.145-152
Mots-clés : autism spectrum disorder clinical trials outcome measurement repetitive behavior risperidone Index. décimale : PER Périodiques Résumé : Repetitive behavior is a core feature of autism spectrum disorder. We used 8-week data from two federally funded, multi-site, randomized trials with risperidone conducted by the Research Units on Pediatric Psychopharmacology Autism Network to evaluate the sensitivity of the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder to detect change with treatment. Study 1 included 52 subjects assigned to placebo and 49 subjects to risperidone under double-blind conditions. In Study 2, 49 subjects received risperidone only and 75 subjects received risperidone plus parent training. The combined sample consisted of 187 boys and 38 girls (aged 4–17?years). At the medication-free baseline, the internal consistency on the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder total score was excellent (Cronbach’s alpha = 0.84) and the mean scores were similar across the four groups. Compared to placebo in Study 1, all three active treatment groups showed significant improvement (effect sizes: 0.74–0.88). There were no differences between active treatment groups. These results indicate that the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder has acceptable test–retest as evidenced by the medium to high correlations in the placebo group and demonstrated sensitivity to change with treatment. En ligne : http://dx.doi.org/10.1177/1362361315574889 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 The Repetitive Behavior Scale-Revised: Independent Validation in Individuals with Autism Spectrum Disorders / Kristen S. L. LAM in Journal of Autism and Developmental Disorders, 37-5 (May 2007)
[article]
Titre : The Repetitive Behavior Scale-Revised: Independent Validation in Individuals with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Kristen S. L. LAM, Auteur ; Michael G. AMAN, Auteur Année de publication : 2007 Article en page(s) : p.855-866 Langues : Anglais (eng) Mots-clés : Autism Repetitive-behavior Stereotypies Assessment Rating-scale Index. décimale : PER Périodiques Résumé : A key feature of autism is restricted repetitive behavior (RRB). Despite the significance of RRBs, little is known about their phenomenology, assessment, and treatment. The Repetitive Behavior Scale-Revised (RBS-R) is a recently-developed questionnaire that captures the breadth of RRB in autism. To validate the RBS-R in an independent sample, we conducted a survey within the South Carolina Autism Society. A total of 320 caregivers (32%) responded. Factor analysis produced a five-factor solution that was clinically meaningful and statistically sound. The factors were labeled “Ritualistic/Sameness Behavior,” “Stereotypic Behavior,” “Self-injurious Behavior,” “Compulsive Behavior,” and “Restricted Interests.” Measures of internal consistency were high for this solution, and interrater reliability data suggested that the RBS-R performs well in outpatient settings.
En ligne : http://dx.doi.org/10.1007/s10803-006-0213-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=140
in Journal of Autism and Developmental Disorders > 37-5 (May 2007) . - p.855-866[article] The Repetitive Behavior Scale-Revised: Independent Validation in Individuals with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Kristen S. L. LAM, Auteur ; Michael G. AMAN, Auteur . - 2007 . - p.855-866.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 37-5 (May 2007) . - p.855-866
Mots-clés : Autism Repetitive-behavior Stereotypies Assessment Rating-scale Index. décimale : PER Périodiques Résumé : A key feature of autism is restricted repetitive behavior (RRB). Despite the significance of RRBs, little is known about their phenomenology, assessment, and treatment. The Repetitive Behavior Scale-Revised (RBS-R) is a recently-developed questionnaire that captures the breadth of RRB in autism. To validate the RBS-R in an independent sample, we conducted a survey within the South Carolina Autism Society. A total of 320 caregivers (32%) responded. Factor analysis produced a five-factor solution that was clinically meaningful and statistically sound. The factors were labeled “Ritualistic/Sameness Behavior,” “Stereotypic Behavior,” “Self-injurious Behavior,” “Compulsive Behavior,” and “Restricted Interests.” Measures of internal consistency were high for this solution, and interrater reliability data suggested that the RBS-R performs well in outpatient settings.
En ligne : http://dx.doi.org/10.1007/s10803-006-0213-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=140 Trial Design Challenges When Combining Medication and Parent Training in Children with Pervasive Developmental Disorders / Lawrence SCAHILL in Journal of Autism and Developmental Disorders, 39-5 (May 2009)
[article]
Titre : Trial Design Challenges When Combining Medication and Parent Training in Children with Pervasive Developmental Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Lawrence SCAHILL, Auteur ; Kimberly A. STIGLER, Auteur ; James MULICK, Auteur ; Eric BUTTER, Auteur ; James DZIURA, Auteur ; Cynthia JOHNSON, Auteur ; Karen E. BEARSS, Auteur ; Louise RITZ, Auteur ; Christopher J. MCDOUGLE, Auteur ; Naomi SWIEZY, Auteur ; Michael G. AMAN, Auteur ; Benjamin L. HANDEN, Auteur ; Denis G. SUKHODOLSKY, Auteur ; Benedetto VITIELLO, Auteur ; L. Eugene ARNOLD, Auteur ; Ann WAGNER, Auteur ; James T. MCCRACKEN, Auteur Année de publication : 2009 Article en page(s) : p.720-729 Langues : Anglais (eng) Mots-clés : Autism Clinical-trial-methodology Risperidone Behavior-therapy Index. décimale : PER Périodiques Résumé : This paper presents the rationale for a 24-week, randomized trial designed to test whether risperidone plus structured parent training would be superior to risperidone only on measures of noncompliance, irritability and adaptive functioning. In this model, medication reduces tantrums, aggression and self-injury; parent training promotes improvement in noncompliance and adaptive functioning. Thus, medication and parent training target related, but separate, outcomes. At week 24, the medication was gradually withdrawn to determine whether subjects in the combined treatment group could be managed on a lower dose or off medication without relapse. Both symptom reduction and functional improvement are important clinical treatment targets. Thus, experimental evidence on the beneficial effects of combining pharmacotherapy and exportable behavioral interventions is needed to guide clinical practice. En ligne : http://dx.doi.org/10.1007/s10803-008-0675-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=732
in Journal of Autism and Developmental Disorders > 39-5 (May 2009) . - p.720-729[article] Trial Design Challenges When Combining Medication and Parent Training in Children with Pervasive Developmental Disorders [Texte imprimé et/ou numérique] / Lawrence SCAHILL, Auteur ; Kimberly A. STIGLER, Auteur ; James MULICK, Auteur ; Eric BUTTER, Auteur ; James DZIURA, Auteur ; Cynthia JOHNSON, Auteur ; Karen E. BEARSS, Auteur ; Louise RITZ, Auteur ; Christopher J. MCDOUGLE, Auteur ; Naomi SWIEZY, Auteur ; Michael G. AMAN, Auteur ; Benjamin L. HANDEN, Auteur ; Denis G. SUKHODOLSKY, Auteur ; Benedetto VITIELLO, Auteur ; L. Eugene ARNOLD, Auteur ; Ann WAGNER, Auteur ; James T. MCCRACKEN, Auteur . - 2009 . - p.720-729.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 39-5 (May 2009) . - p.720-729
Mots-clés : Autism Clinical-trial-methodology Risperidone Behavior-therapy Index. décimale : PER Périodiques Résumé : This paper presents the rationale for a 24-week, randomized trial designed to test whether risperidone plus structured parent training would be superior to risperidone only on measures of noncompliance, irritability and adaptive functioning. In this model, medication reduces tantrums, aggression and self-injury; parent training promotes improvement in noncompliance and adaptive functioning. Thus, medication and parent training target related, but separate, outcomes. At week 24, the medication was gradually withdrawn to determine whether subjects in the combined treatment group could be managed on a lower dose or off medication without relapse. Both symptom reduction and functional improvement are important clinical treatment targets. Thus, experimental evidence on the beneficial effects of combining pharmacotherapy and exportable behavioral interventions is needed to guide clinical practice. En ligne : http://dx.doi.org/10.1007/s10803-008-0675-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=732 Using qualitative methods to guide scale development for anxiety in youth with autism spectrum disorder / Karen E. BEARSS in Autism, 20-6 (August 2016)
[article]
Titre : Using qualitative methods to guide scale development for anxiety in youth with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Karen E. BEARSS, Auteur ; Christopher A TAYLOR, Auteur ; Michael G. AMAN, Auteur ; Robin WHITTEMORE, Auteur ; Luc LECAVALIER, Auteur ; Judith MILLER, Auteur ; Jill PRITCHETT, Auteur ; Bryson GREEN, Auteur ; Lawrence SCAHILL, Auteur Article en page(s) : p.663-672 Langues : Anglais (eng) Mots-clés : anxiety autism spectrum disorder content validity focus group instrument development qualitative methods Index. décimale : PER Périodiques Résumé : Anxiety is common in youth with autism spectrum disorder. Despite this common co-occurrence, studies targeting anxiety in this population are hindered by the under-developed state of measures in youth with autism spectrum disorder. Content validity (the extent to which an instrument measures the domain of interest) and an instrument’s relevance to the patient population are key components of measurement development. This article describes the application of qualitative research methods in the initial development of a parent-rated instrument of anxiety symptoms in youth with autism spectrum disorder. Overall, 48 parents of 45 children (aged 3–17?years) with autism spectrum disorder and at least mild anxiety participated in one of six focus groups at two sites (three groups per site). Systematic coding of the focus group transcripts identified broad themes reflecting the situations and events that trigger anxiety in children with autism spectrum disorder, the behavioral manifestations of anxiety in children with autism spectrum disorder, the parent and the child’s own response to anxiety, and broad behavioral patterns that could be associated with anxiety. From the focus group data, investigators generated 52 candidate items for a parent-rating of anxiety in youth with autism spectrum disorder. This report provides a detailed description of these early steps in developing a patient-oriented outcome measure. En ligne : http://dx.doi.org/10.1177/1362361315601012 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290
in Autism > 20-6 (August 2016) . - p.663-672[article] Using qualitative methods to guide scale development for anxiety in youth with autism spectrum disorder [Texte imprimé et/ou numérique] / Karen E. BEARSS, Auteur ; Christopher A TAYLOR, Auteur ; Michael G. AMAN, Auteur ; Robin WHITTEMORE, Auteur ; Luc LECAVALIER, Auteur ; Judith MILLER, Auteur ; Jill PRITCHETT, Auteur ; Bryson GREEN, Auteur ; Lawrence SCAHILL, Auteur . - p.663-672.
Langues : Anglais (eng)
in Autism > 20-6 (August 2016) . - p.663-672
Mots-clés : anxiety autism spectrum disorder content validity focus group instrument development qualitative methods Index. décimale : PER Périodiques Résumé : Anxiety is common in youth with autism spectrum disorder. Despite this common co-occurrence, studies targeting anxiety in this population are hindered by the under-developed state of measures in youth with autism spectrum disorder. Content validity (the extent to which an instrument measures the domain of interest) and an instrument’s relevance to the patient population are key components of measurement development. This article describes the application of qualitative research methods in the initial development of a parent-rated instrument of anxiety symptoms in youth with autism spectrum disorder. Overall, 48 parents of 45 children (aged 3–17?years) with autism spectrum disorder and at least mild anxiety participated in one of six focus groups at two sites (three groups per site). Systematic coding of the focus group transcripts identified broad themes reflecting the situations and events that trigger anxiety in children with autism spectrum disorder, the behavioral manifestations of anxiety in children with autism spectrum disorder, the parent and the child’s own response to anxiety, and broad behavioral patterns that could be associated with anxiety. From the focus group data, investigators generated 52 candidate items for a parent-rating of anxiety in youth with autism spectrum disorder. This report provides a detailed description of these early steps in developing a patient-oriented outcome measure. En ligne : http://dx.doi.org/10.1177/1362361315601012 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290 Validity of the Aberrant Behavior Checklist in Children with Autism Spectrum Disorder / Aaron J. KAAT in Journal of Autism and Developmental Disorders, 44-5 (May 2014)
[article]
Titre : Validity of the Aberrant Behavior Checklist in Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Aaron J. KAAT, Auteur ; Luc LECAVALIER, Auteur ; Michael G. AMAN, Auteur Année de publication : 2014 Article en page(s) : p.1103-1116 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Aberrant Behavior Checklist Factor analysis Irritability Rating scales Assessment Index. décimale : PER Périodiques Résumé : The Aberrant Behavior Checklist (ABC) is a widely used measure in autism spectrum disorder (ASD) treatment studies. We conducted confirmatory and exploratory factor analyses of the ABC in 1,893 children evaluated as part of the Autism Treatment Network. The root mean square error of approximation was .086 for the standard item assignment, and in exploratory factor analysis, the large majority of items continued to load on the originally assigned factors. Correlations between the ABC subscales and multiple external variables including the Child Behavior Checklist and demographic variables supported the convergent and divergent validity of the ABC as a measure of behavior problems in ASD. Finally, we examined the impact of participant characteristics on subscale scores and present normative data. En ligne : http://dx.doi.org/10.1007/s10803-013-1970-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232
in Journal of Autism and Developmental Disorders > 44-5 (May 2014) . - p.1103-1116[article] Validity of the Aberrant Behavior Checklist in Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Aaron J. KAAT, Auteur ; Luc LECAVALIER, Auteur ; Michael G. AMAN, Auteur . - 2014 . - p.1103-1116.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 44-5 (May 2014) . - p.1103-1116
Mots-clés : Autism spectrum disorder Aberrant Behavior Checklist Factor analysis Irritability Rating scales Assessment Index. décimale : PER Périodiques Résumé : The Aberrant Behavior Checklist (ABC) is a widely used measure in autism spectrum disorder (ASD) treatment studies. We conducted confirmatory and exploratory factor analyses of the ABC in 1,893 children evaluated as part of the Autism Treatment Network. The root mean square error of approximation was .086 for the standard item assignment, and in exploratory factor analysis, the large majority of items continued to load on the originally assigned factors. Correlations between the ABC subscales and multiple external variables including the Child Behavior Checklist and demographic variables supported the convergent and divergent validity of the ABC as a measure of behavior problems in ASD. Finally, we examined the impact of participant characteristics on subscale scores and present normative data. En ligne : http://dx.doi.org/10.1007/s10803-013-1970-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232 What Is the Value of Medication in ASC? / L. Eugene ARNOLD
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