Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur Venkat BHAT |
Documents disponibles écrits par cet auteur (1)
Faire une suggestion Affiner la recherche
Parental psychopathology in families of children with attention-deficit/hyperactivity disorder and exposed to maternal smoking during pregnancy / Sarojini M. SENGUPTA in Journal of Child Psychology and Psychiatry, 56-2 (February 2015)
[article]
Titre : Parental psychopathology in families of children with attention-deficit/hyperactivity disorder and exposed to maternal smoking during pregnancy Type de document : Texte imprimé et/ou numérique Auteurs : Sarojini M. SENGUPTA, Auteur ; Marie-Eve FORTIER, Auteur ; Geeta A. THAKUR, Auteur ; Venkat BHAT, Auteur ; Natalie GRIZENKO, Auteur ; Ridha JOOBER, Auteur Article en page(s) : p.122-129 Langues : Anglais (eng) Mots-clés : Attention-deficit/hyperactivity disorder behavior problems comorbidity family history smoking Index. décimale : PER Périodiques Résumé : Background Both genetic and environmental factors have been implicated in the etiology of attention-deficit/hyperactivity disorder (ADHD). We had previously suggested that exposure to maternal smoking during pregnancy (MSDP) may be a valid basis for delineating a distinct subtype of ADHD, where children exposed to MSDP present with a more severe clinical picture. Here, we examine the psychopathology of parents in this group, to better understand the etiology of ADHD. Methods Using the Family Interview for Genetic Studies in a sample of 514 families of children with ADHD, we collected data pertaining to lifetime parental psychopathology. Families were stratified based on maternal smoking during the complete gestational period. The frequency of different disorders was compared using the ?2 statistic. Results In the group where mothers smoked during pregnancy, both parents were significantly more likely to have antisocial personality disorder, and problems with alcohol and drug abuse. Mothers had a significantly higher frequency of major depressive disorder (MDD), while fathers showed a trend for both MDD and bipolar disorder. Conclusions Based on the pattern of psychopathology in parents of children exposed to MSDP, as well as earlier reports of the severe clinical, behavioral, and cognitive phenotype in these children, combined with the large body of epidemiological evidence, we propose that these children present a distinct subtype of ADHD with comorbid conduct disorder. Furthermore, we propose that MSDP may be a proxy measure to help delineate this subtype. En ligne : http://dx.doi.org/10.1111/jcpp.12286 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259
in Journal of Child Psychology and Psychiatry > 56-2 (February 2015) . - p.122-129[article] Parental psychopathology in families of children with attention-deficit/hyperactivity disorder and exposed to maternal smoking during pregnancy [Texte imprimé et/ou numérique] / Sarojini M. SENGUPTA, Auteur ; Marie-Eve FORTIER, Auteur ; Geeta A. THAKUR, Auteur ; Venkat BHAT, Auteur ; Natalie GRIZENKO, Auteur ; Ridha JOOBER, Auteur . - p.122-129.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-2 (February 2015) . - p.122-129
Mots-clés : Attention-deficit/hyperactivity disorder behavior problems comorbidity family history smoking Index. décimale : PER Périodiques Résumé : Background Both genetic and environmental factors have been implicated in the etiology of attention-deficit/hyperactivity disorder (ADHD). We had previously suggested that exposure to maternal smoking during pregnancy (MSDP) may be a valid basis for delineating a distinct subtype of ADHD, where children exposed to MSDP present with a more severe clinical picture. Here, we examine the psychopathology of parents in this group, to better understand the etiology of ADHD. Methods Using the Family Interview for Genetic Studies in a sample of 514 families of children with ADHD, we collected data pertaining to lifetime parental psychopathology. Families were stratified based on maternal smoking during the complete gestational period. The frequency of different disorders was compared using the ?2 statistic. Results In the group where mothers smoked during pregnancy, both parents were significantly more likely to have antisocial personality disorder, and problems with alcohol and drug abuse. Mothers had a significantly higher frequency of major depressive disorder (MDD), while fathers showed a trend for both MDD and bipolar disorder. Conclusions Based on the pattern of psychopathology in parents of children exposed to MSDP, as well as earlier reports of the severe clinical, behavioral, and cognitive phenotype in these children, combined with the large body of epidemiological evidence, we propose that these children present a distinct subtype of ADHD with comorbid conduct disorder. Furthermore, we propose that MSDP may be a proxy measure to help delineate this subtype. En ligne : http://dx.doi.org/10.1111/jcpp.12286 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259