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Détail de l'auteur
Auteur Radha KOTHARI |
Documents disponibles écrits par cet auteur (2)
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Social communication and emotion difficulties and second to fourth digit ratio in a large community-based sample / Manuela BARONA in Molecular Autism, (December 2015)
[article]
Titre : Social communication and emotion difficulties and second to fourth digit ratio in a large community-based sample Type de document : Texte imprimé et/ou numérique Auteurs : Manuela BARONA, Auteur ; Radha KOTHARI, Auteur ; David SKUSE, Auteur ; Nadia MICALI, Auteur Article en page(s) : p.1-11 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Recent research investigating the extreme male brain theory of autism spectrum disorders (ASD) has drawn attention to the possibility that autistic type social difficulties may be associated with high prenatal testosterone exposure. This study aims to investigate the association between social communication and emotion recognition difficulties and second to fourth digit ratio (2D:4D) and circulating maternal testosterone during pregnancy in a large community-based cohort: the Avon Longitudinal Study of Parents and Children (ALSPAC). A secondary aim is to investigate possible gender differences in the associations. En ligne : http://dx.doi.org/10.1186/s13229-015-0063-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277
in Molecular Autism > (December 2015) . - p.1-11[article] Social communication and emotion difficulties and second to fourth digit ratio in a large community-based sample [Texte imprimé et/ou numérique] / Manuela BARONA, Auteur ; Radha KOTHARI, Auteur ; David SKUSE, Auteur ; Nadia MICALI, Auteur . - p.1-11.
Langues : Anglais (eng)
in Molecular Autism > (December 2015) . - p.1-11
Index. décimale : PER Périodiques Résumé : Recent research investigating the extreme male brain theory of autism spectrum disorders (ASD) has drawn attention to the possibility that autistic type social difficulties may be associated with high prenatal testosterone exposure. This study aims to investigate the association between social communication and emotion recognition difficulties and second to fourth digit ratio (2D:4D) and circulating maternal testosterone during pregnancy in a large community-based cohort: the Avon Longitudinal Study of Parents and Children (ALSPAC). A secondary aim is to investigate possible gender differences in the associations. En ligne : http://dx.doi.org/10.1186/s13229-015-0063-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 Trajectories of autistic social traits in childhood and adolescence and disordered eating behaviours at age 14 years: A UK general population cohort study / Francesca SOLMI in Journal of Child Psychology and Psychiatry, 62-1 (January 2021)
[article]
Titre : Trajectories of autistic social traits in childhood and adolescence and disordered eating behaviours at age 14 years: A UK general population cohort study Type de document : Texte imprimé et/ou numérique Auteurs : Francesca SOLMI, Auteur ; Francesca BENTIVEGNA, Auteur ; Helen BOULD, Auteur ; William MANDY, Auteur ; Radha KOTHARI, Auteur ; Dheeraj RAI, Auteur ; David SKUSE, Auteur ; Glyn LEWIS, Auteur Article en page(s) : p.75-85 Langues : Anglais (eng) Mots-clés : Alspac autistic traits cohort study eating disorders trajectories Index. décimale : PER Périodiques Résumé : BACKGROUND: Some people with eating disorders have difficulties with social communication. However, no longitudinal evidence regarding the direction of this association exists. We investigated trajectories of autistic social traits across childhood and adolescence in adolescents with and without disordered eating behaviours in early adolescence. METHODS: We used data from the Avon Longitudinal Study of Parents and Children. Our disordered eating measure indicated presence of any, monthly and weekly disordered eating (fasting, purging, dieting, binge eating) at age 14 years. Autistic social traits were reported by mothers using the Social and Communication Disorders Checklist (SCDC) at age seven, 11, 14 and 16 years. We modelled SCDC score trajectories using multilevel negative binomial models adjusting for a number of child- and maternal-level confounders. RESULTS: Of the 5,381 adolescents included in our sample, 421 (7.8%) experienced one or more disordered eating behaviours, and 148 (2.8%) weekly episodes. Adolescents with disordered eating had a 20% increase in SCDC scores (relative risk (RR) 1.23, 95% confidence interval (CI):1.14, 1.32) compared to those without disordered eating. This association was particularly apparent for those reporting weekly (RR 1.43, 95%CI: 1.27, 1.61) as opposed to monthly disordered eating (RR 1.12, 95%CI: 1.01, 1.22). CONCLUSIONS: Greater autistic social traits in childhood could represent a risk factor for the development of disordered eating in adolescence. Although mechanisms of this association need to be elucidated, clinicians should be aware that autistic social traits could have predated the eating disorder when managing people with these conditions. En ligne : http://dx.doi.org/10.1111/jcpp.13255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435
in Journal of Child Psychology and Psychiatry > 62-1 (January 2021) . - p.75-85[article] Trajectories of autistic social traits in childhood and adolescence and disordered eating behaviours at age 14 years: A UK general population cohort study [Texte imprimé et/ou numérique] / Francesca SOLMI, Auteur ; Francesca BENTIVEGNA, Auteur ; Helen BOULD, Auteur ; William MANDY, Auteur ; Radha KOTHARI, Auteur ; Dheeraj RAI, Auteur ; David SKUSE, Auteur ; Glyn LEWIS, Auteur . - p.75-85.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-1 (January 2021) . - p.75-85
Mots-clés : Alspac autistic traits cohort study eating disorders trajectories Index. décimale : PER Périodiques Résumé : BACKGROUND: Some people with eating disorders have difficulties with social communication. However, no longitudinal evidence regarding the direction of this association exists. We investigated trajectories of autistic social traits across childhood and adolescence in adolescents with and without disordered eating behaviours in early adolescence. METHODS: We used data from the Avon Longitudinal Study of Parents and Children. Our disordered eating measure indicated presence of any, monthly and weekly disordered eating (fasting, purging, dieting, binge eating) at age 14 years. Autistic social traits were reported by mothers using the Social and Communication Disorders Checklist (SCDC) at age seven, 11, 14 and 16 years. We modelled SCDC score trajectories using multilevel negative binomial models adjusting for a number of child- and maternal-level confounders. RESULTS: Of the 5,381 adolescents included in our sample, 421 (7.8%) experienced one or more disordered eating behaviours, and 148 (2.8%) weekly episodes. Adolescents with disordered eating had a 20% increase in SCDC scores (relative risk (RR) 1.23, 95% confidence interval (CI):1.14, 1.32) compared to those without disordered eating. This association was particularly apparent for those reporting weekly (RR 1.43, 95%CI: 1.27, 1.61) as opposed to monthly disordered eating (RR 1.12, 95%CI: 1.01, 1.22). CONCLUSIONS: Greater autistic social traits in childhood could represent a risk factor for the development of disordered eating in adolescence. Although mechanisms of this association need to be elucidated, clinicians should be aware that autistic social traits could have predated the eating disorder when managing people with these conditions. En ligne : http://dx.doi.org/10.1111/jcpp.13255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435