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Auteur Dheeraj RAI |
Documents disponibles écrits par cet auteur (13)
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Anxiety Disorders in Adults with Autism Spectrum Disorder: A Population-Based Study / Victoria NIMMO-SMITH in Journal of Autism and Developmental Disorders, 50-1 (January 2020)
[article]
Titre : Anxiety Disorders in Adults with Autism Spectrum Disorder: A Population-Based Study Type de document : Texte imprimé et/ou numérique Auteurs : Victoria NIMMO-SMITH, Auteur ; Hein HEUVELMAN, Auteur ; Christina DALMAN, Auteur ; Michael LUNDBERG, Auteur ; Selma IDRING, Auteur ; Peter CARPENTER, Auteur ; Cecilia MAGNUSSON, Auteur ; Dheeraj RAI, Auteur Article en page(s) : p.308-318 Langues : Anglais (eng) Mots-clés : Anxiety Autism spectrum disorder Epidemiology Intellectual disability Mental health Index. décimale : PER Périodiques Résumé : Anxiety is common in children with ASD; however, the burden of specific anxiety disorders for adults with ASD is under-researched. Using the Stockholm Youth Cohort, we compared anxiety disorder diagnoses among autistic adults (n = 4049), with or without intellectual disability, and population controls (n = 217,645). We conducted additional sibling analyses. Anxiety disorders were diagnosed in 20.1% of adults with ASD compared with 8.7% of controls (RR = 2.62 [95% CI 2.47-2.79]), with greatest risk for autistic people without intellectual disability. Rates of almost all individual anxiety disorders were raised, notably obsessive-compulsive disorder and phobic anxiety disorders. Anxiety disorders were more common in full siblings and half-siblings of people with ASD. The implications of this are explored. En ligne : http://dx.doi.org/10.1007/s10803-019-04234-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414
in Journal of Autism and Developmental Disorders > 50-1 (January 2020) . - p.308-318[article] Anxiety Disorders in Adults with Autism Spectrum Disorder: A Population-Based Study [Texte imprimé et/ou numérique] / Victoria NIMMO-SMITH, Auteur ; Hein HEUVELMAN, Auteur ; Christina DALMAN, Auteur ; Michael LUNDBERG, Auteur ; Selma IDRING, Auteur ; Peter CARPENTER, Auteur ; Cecilia MAGNUSSON, Auteur ; Dheeraj RAI, Auteur . - p.308-318.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 50-1 (January 2020) . - p.308-318
Mots-clés : Anxiety Autism spectrum disorder Epidemiology Intellectual disability Mental health Index. décimale : PER Périodiques Résumé : Anxiety is common in children with ASD; however, the burden of specific anxiety disorders for adults with ASD is under-researched. Using the Stockholm Youth Cohort, we compared anxiety disorder diagnoses among autistic adults (n = 4049), with or without intellectual disability, and population controls (n = 217,645). We conducted additional sibling analyses. Anxiety disorders were diagnosed in 20.1% of adults with ASD compared with 8.7% of controls (RR = 2.62 [95% CI 2.47-2.79]), with greatest risk for autistic people without intellectual disability. Rates of almost all individual anxiety disorders were raised, notably obsessive-compulsive disorder and phobic anxiety disorders. Anxiety disorders were more common in full siblings and half-siblings of people with ASD. The implications of this are explored. En ligne : http://dx.doi.org/10.1007/s10803-019-04234-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414 Benefits and harms of interventions to improve anxiety, depression, and other mental health outcomes for autistic people: A systematic review and network meta-analysis of randomised controlled trials / Audrey LINDEN in Autism, 27-1 (January 2023)
[article]
Titre : Benefits and harms of interventions to improve anxiety, depression, and other mental health outcomes for autistic people: A systematic review and network meta-analysis of randomised controlled trials Type de document : Texte imprimé et/ou numérique Auteurs : Audrey LINDEN, Auteur ; Lawrence BEST, Auteur ; Freya ELISE, Auteur ; Danielle ROBERTS, Auteur ; Aoife BRANAGAN, Auteur ; Yong Boon Ernest TAY, Auteur ; Laura CRANE, Auteur ; James CUSACK, Auteur ; Brian DAVIDSON, Auteur ; Ian DAVIDSON, Auteur ; Caroline HEARST, Auteur ; William MANDY, Auteur ; Dheeraj RAI, Auteur ; Edward SMITH, Auteur ; Kurinchi GURUSAMY, Auteur Article en page(s) : p.7-30 Langues : Anglais (eng) Mots-clés : adolescents adults anxiety autism spectrum disorders depression interventions - pharmacologic interventions - psychosocial/behavioural school-age children Index. décimale : PER Périodiques Résumé : Mental health difficulties are prevalent in autistic people with ~14%-50% having experienced depression and ~40%-80% having experienced anxiety disorders. Identifying interventions that improve autistic people’s mental health is a top priority. However, at present, there is no high-quality network meta-analysis of benefits and harms of different interventions. We conducted a systematic review and network meta-analysis of randomised controlled trials, searching MEDLINE, EMBASE, other databases, and trial registers until 17 October 2020. We included randomised controlled trials reporting anxiety or depression in a suitable format. We calculated effect estimates and 95% credible intervals using Bayesian network meta-analysis. Our search identified 13,794 reports, of which 71 randomised controlled trials (3630 participants) were eligible for inclusion. All trials had high risk of bias. The follow-up period ranged from 1 to 24 months. Evidence indicates uncertainty about the effects of different interventions, with more high-quality evidence needed. Available evidence suggests that some forms of cognitive behavioural therapy may decrease anxiety and depression scores in autistic children and adults; mindfulness therapy may decrease anxiety and depression scores in autistic adults with previous mental health conditions; and behavioural interventions may provide some benefit for depression in autistic children. We recommend that autistic people are given access to mental health interventions available to non-autistic people, following principles of person-centred care. PROSPERO registration ID: CRD42019136093 Lay Abstract Nearly three out of four autistic people experience mental health problems such as stress, anxiety or depression. The research already done does not guide us on how best to prevent or treat mental health problems for autistic people. Our aim was to look at the benefits and harms of different interventions on mental health outcomes in autistic people. We searched all the published randomised controlled trials (RCTs) about interventions for mental health conditions in autistic people until 17 October 2020. We also searched for RCTs that were not published in peer-reviewed journals. These were obtained from registers of clinical trials online. We then combined the information from all these trials using advanced statistical methods to analyse how good the interventions are. Seventy-one studies (3630 participants) provided information for this research. The studies reported how participants were responding to the intervention for only a short period of time. The trials did not report which interventions worked for people with intellectual disability. In people without intellectual disability, some forms of cognitive behavioural therapy and mindfulness therapy may be helpful. However, further research is necessary. Many trials used medications to target core features of autism rather than targeting mental health conditions, but these medications did not help autistic people. Until we have more evidence, treatment of mental health conditions in autistic people should follow the evidence available for non-autistic people. We plan to widely disseminate the findings to healthcare professionals through medical journals and conferences and contact other groups representing autistic people. En ligne : http://dx.doi.org/10.1177/13623613221117931 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=491
in Autism > 27-1 (January 2023) . - p.7-30[article] Benefits and harms of interventions to improve anxiety, depression, and other mental health outcomes for autistic people: A systematic review and network meta-analysis of randomised controlled trials [Texte imprimé et/ou numérique] / Audrey LINDEN, Auteur ; Lawrence BEST, Auteur ; Freya ELISE, Auteur ; Danielle ROBERTS, Auteur ; Aoife BRANAGAN, Auteur ; Yong Boon Ernest TAY, Auteur ; Laura CRANE, Auteur ; James CUSACK, Auteur ; Brian DAVIDSON, Auteur ; Ian DAVIDSON, Auteur ; Caroline HEARST, Auteur ; William MANDY, Auteur ; Dheeraj RAI, Auteur ; Edward SMITH, Auteur ; Kurinchi GURUSAMY, Auteur . - p.7-30.
Langues : Anglais (eng)
in Autism > 27-1 (January 2023) . - p.7-30
Mots-clés : adolescents adults anxiety autism spectrum disorders depression interventions - pharmacologic interventions - psychosocial/behavioural school-age children Index. décimale : PER Périodiques Résumé : Mental health difficulties are prevalent in autistic people with ~14%-50% having experienced depression and ~40%-80% having experienced anxiety disorders. Identifying interventions that improve autistic people’s mental health is a top priority. However, at present, there is no high-quality network meta-analysis of benefits and harms of different interventions. We conducted a systematic review and network meta-analysis of randomised controlled trials, searching MEDLINE, EMBASE, other databases, and trial registers until 17 October 2020. We included randomised controlled trials reporting anxiety or depression in a suitable format. We calculated effect estimates and 95% credible intervals using Bayesian network meta-analysis. Our search identified 13,794 reports, of which 71 randomised controlled trials (3630 participants) were eligible for inclusion. All trials had high risk of bias. The follow-up period ranged from 1 to 24 months. Evidence indicates uncertainty about the effects of different interventions, with more high-quality evidence needed. Available evidence suggests that some forms of cognitive behavioural therapy may decrease anxiety and depression scores in autistic children and adults; mindfulness therapy may decrease anxiety and depression scores in autistic adults with previous mental health conditions; and behavioural interventions may provide some benefit for depression in autistic children. We recommend that autistic people are given access to mental health interventions available to non-autistic people, following principles of person-centred care. PROSPERO registration ID: CRD42019136093 Lay Abstract Nearly three out of four autistic people experience mental health problems such as stress, anxiety or depression. The research already done does not guide us on how best to prevent or treat mental health problems for autistic people. Our aim was to look at the benefits and harms of different interventions on mental health outcomes in autistic people. We searched all the published randomised controlled trials (RCTs) about interventions for mental health conditions in autistic people until 17 October 2020. We also searched for RCTs that were not published in peer-reviewed journals. These were obtained from registers of clinical trials online. We then combined the information from all these trials using advanced statistical methods to analyse how good the interventions are. Seventy-one studies (3630 participants) provided information for this research. The studies reported how participants were responding to the intervention for only a short period of time. The trials did not report which interventions worked for people with intellectual disability. In people without intellectual disability, some forms of cognitive behavioural therapy and mindfulness therapy may be helpful. However, further research is necessary. Many trials used medications to target core features of autism rather than targeting mental health conditions, but these medications did not help autistic people. Until we have more evidence, treatment of mental health conditions in autistic people should follow the evidence available for non-autistic people. We plan to widely disseminate the findings to healthcare professionals through medical journals and conferences and contact other groups representing autistic people. En ligne : http://dx.doi.org/10.1177/13623613221117931 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=491 Brief Report: Maternal Smoking During Pregnancy and Autism Spectrum Disorders / Brian K. LEE in Journal of Autism and Developmental Disorders, 42-9 (September 2012)
[article]
Titre : Brief Report: Maternal Smoking During Pregnancy and Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Brian K. LEE, Auteur ; Renee M. GARDNER, Auteur ; Henrik DAL, Auteur ; Anna SVENSSON, Auteur ; Maria Rosaria GALANTI, Auteur ; Dheeraj RAI, Auteur ; Christina DALMAN, Auteur ; Cecilia MAGNUSSON, Auteur Année de publication : 2012 Article en page(s) : p.2000-2005 Langues : Anglais (eng) Mots-clés : Autism Population register Smoking Sweden Tobacco Index. décimale : PER Périodiques Résumé : Prenatal exposure to tobacco smoke is suggested as a potential risk factor for autism spectrum disorders (ASD). Previous epidemiological studies of this topic have yielded mixed findings. We performed a case–control study of 3,958 ASD cases and 38,983 controls nested in a large register-based cohort in Sweden. ASD case status was measured using a multisource case ascertainment system. In adjusted results, we found that maternal smoking during pregnancy is not associated with increased risk of ASD regardless of presence or absence of comorbid intellectual disability. Apparent associations were attributable to confounding by sociodemographic characteristics of parents such as education, income, and occupation. En ligne : http://dx.doi.org/10.1007/s10803-011-1425-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180
in Journal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.2000-2005[article] Brief Report: Maternal Smoking During Pregnancy and Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Brian K. LEE, Auteur ; Renee M. GARDNER, Auteur ; Henrik DAL, Auteur ; Anna SVENSSON, Auteur ; Maria Rosaria GALANTI, Auteur ; Dheeraj RAI, Auteur ; Christina DALMAN, Auteur ; Cecilia MAGNUSSON, Auteur . - 2012 . - p.2000-2005.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.2000-2005
Mots-clés : Autism Population register Smoking Sweden Tobacco Index. décimale : PER Périodiques Résumé : Prenatal exposure to tobacco smoke is suggested as a potential risk factor for autism spectrum disorders (ASD). Previous epidemiological studies of this topic have yielded mixed findings. We performed a case–control study of 3,958 ASD cases and 38,983 controls nested in a large register-based cohort in Sweden. ASD case status was measured using a multisource case ascertainment system. In adjusted results, we found that maternal smoking during pregnancy is not associated with increased risk of ASD regardless of presence or absence of comorbid intellectual disability. Apparent associations were attributable to confounding by sociodemographic characteristics of parents such as education, income, and occupation. En ligne : http://dx.doi.org/10.1007/s10803-011-1425-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180 Brief Report: Prevalence of Co-occurring Epilepsy and Autism Spectrum Disorder: The U.S. National Survey of Children’s Health 2011–2012 / Shiny THOMAS in Journal of Autism and Developmental Disorders, 47-1 (January 2017)
[article]
Titre : Brief Report: Prevalence of Co-occurring Epilepsy and Autism Spectrum Disorder: The U.S. National Survey of Children’s Health 2011–2012 Type de document : Texte imprimé et/ou numérique Auteurs : Shiny THOMAS, Auteur ; Mary E. HOVINGA, Auteur ; Dheeraj RAI, Auteur ; Brian K. LEE, Auteur Article en page(s) : p.224-229 Langues : Anglais (eng) Mots-clés : Autism Epilepsy Comorbid Epidemiology Index. décimale : PER Périodiques Résumé : Epilepsy is reported to co-occur in individuals with autism spectrum disorder (ASD). Previous studies across the world have found prevalence estimates ranging from 4 to 38?%. We examined parent-reported prevalence of co-occurring epilepsy and ASD in the most recent U.S. National Survey of Children’s Health, 2011–2012. All analyses accounted for survey weights to account for the complex sampling design. In the overall analytic sample of 85,248 children ages 2–17, there were 1604 children with ASD (prevalence of 1.8?%) and 1083 children with epilepsy (prevalence of 1.2?%). Epilepsy was reported to co-occur in 8.6?% of ASD cases. In children with ASD, the co-occurrence of epilepsy was associated with increasing child age, female gender, intellectual disability, speech problems and lower socioeconomic status. En ligne : http://dx.doi.org/10.1007/s10803-016-2938-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298
in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.224-229[article] Brief Report: Prevalence of Co-occurring Epilepsy and Autism Spectrum Disorder: The U.S. National Survey of Children’s Health 2011–2012 [Texte imprimé et/ou numérique] / Shiny THOMAS, Auteur ; Mary E. HOVINGA, Auteur ; Dheeraj RAI, Auteur ; Brian K. LEE, Auteur . - p.224-229.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.224-229
Mots-clés : Autism Epilepsy Comorbid Epidemiology Index. décimale : PER Périodiques Résumé : Epilepsy is reported to co-occur in individuals with autism spectrum disorder (ASD). Previous studies across the world have found prevalence estimates ranging from 4 to 38?%. We examined parent-reported prevalence of co-occurring epilepsy and ASD in the most recent U.S. National Survey of Children’s Health, 2011–2012. All analyses accounted for survey weights to account for the complex sampling design. In the overall analytic sample of 85,248 children ages 2–17, there were 1604 children with ASD (prevalence of 1.8?%) and 1083 children with epilepsy (prevalence of 1.2?%). Epilepsy was reported to co-occur in 8.6?% of ASD cases. In children with ASD, the co-occurrence of epilepsy was associated with increasing child age, female gender, intellectual disability, speech problems and lower socioeconomic status. En ligne : http://dx.doi.org/10.1007/s10803-016-2938-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 Changes in Prevalence of Autism Spectrum Disorders in 2001–2011: Findings from the Stockholm Youth Cohort / Selma IDRING in Journal of Autism and Developmental Disorders, 45-6 (June 2015)
[article]
Titre : Changes in Prevalence of Autism Spectrum Disorders in 2001–2011: Findings from the Stockholm Youth Cohort Type de document : Texte imprimé et/ou numérique Auteurs : Selma IDRING, Auteur ; Michael LUNDBERG, Auteur ; Harald STURM, Auteur ; Christina DALMAN, Auteur ; Clara GUMPERT, Auteur ; Dheeraj RAI, Auteur ; Brian K. LEE, Auteur ; Cecilia MAGNUSSON, Auteur Article en page(s) : p.1766-1773 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Intellectual disability Prevalence Time trend Stockholm Sweden Index. décimale : PER Périodiques Résumé : In a record-linkage study in Stockholm, Sweden, the year 2011 prevalence of diagnosed autism spectrum disorders (ASD) was found to be 0.40, 1.74, 2.46, and 1.76 % among 0–5, 6–12, 13–17, and 18–27 year olds, respectively. The corresponding proportion of cases with a recorded diagnosis of intellectual disability was 17.4, 22.1, 26.1 and 29.4 %. Between 2001 and 2011, ASD prevalence increased almost 3.5 fold among children aged 2–17 years. The increase was mainly accounted for by an eightfold increase of ASD without intellectual disability (from 0.14 to 1.10 %), while the prevalence of ASD with intellectual disability increased only slightly (from 0.28 to 0.34 %). The increase in ASD prevalence is likely contributed to by extrinsic factors such as increased awareness and diagnostics. En ligne : http://dx.doi.org/10.1007/s10803-014-2336-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259
in Journal of Autism and Developmental Disorders > 45-6 (June 2015) . - p.1766-1773[article] Changes in Prevalence of Autism Spectrum Disorders in 2001–2011: Findings from the Stockholm Youth Cohort [Texte imprimé et/ou numérique] / Selma IDRING, Auteur ; Michael LUNDBERG, Auteur ; Harald STURM, Auteur ; Christina DALMAN, Auteur ; Clara GUMPERT, Auteur ; Dheeraj RAI, Auteur ; Brian K. LEE, Auteur ; Cecilia MAGNUSSON, Auteur . - p.1766-1773.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-6 (June 2015) . - p.1766-1773
Mots-clés : Autism spectrum disorders Intellectual disability Prevalence Time trend Stockholm Sweden Index. décimale : PER Périodiques Résumé : In a record-linkage study in Stockholm, Sweden, the year 2011 prevalence of diagnosed autism spectrum disorders (ASD) was found to be 0.40, 1.74, 2.46, and 1.76 % among 0–5, 6–12, 13–17, and 18–27 year olds, respectively. The corresponding proportion of cases with a recorded diagnosis of intellectual disability was 17.4, 22.1, 26.1 and 29.4 %. Between 2001 and 2011, ASD prevalence increased almost 3.5 fold among children aged 2–17 years. The increase was mainly accounted for by an eightfold increase of ASD without intellectual disability (from 0.14 to 1.10 %), while the prevalence of ASD with intellectual disability increased only slightly (from 0.28 to 0.34 %). The increase in ASD prevalence is likely contributed to by extrinsic factors such as increased awareness and diagnostics. En ligne : http://dx.doi.org/10.1007/s10803-014-2336-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259 Gendered play behaviours in autistic and non-autistic children: A population-based cohort study / Laura HULL in Autism, 27-5 (July 2023)
PermalinkIntensive behavioural interventions based on applied behaviour analysis for young children with autism: An international collaborative individual participant data meta-analysis / Mark RODGERS in Autism, 25-4 (May 2021)
Permalink“It was like walking without knowing where I was going”: A Qualitative Study of Autism in a UK Somali Migrant Community / Fiona FOX in Journal of Autism and Developmental Disorders, 47-2 (February 2017)
PermalinkMaternal vitamin D during pregnancy and offspring autism and autism-associated traits: a prospective cohort study / Paul MADLEY-DOWD in Molecular Autism, 13 (2022)
PermalinkQualification for upper secondary education in individuals with autism without intellectual disability: Total population study, Stockholm, Sweden / Isidora STARK in Autism, 25-4 (May 2021)
PermalinkThe Familial Risk of Autism Spectrum Disorder with and without Intellectual Disability / Sherlly XIE in Autism Research, 13-12 (December 2020)
PermalinkThe feasibility of low-intensity psychological therapy for depression co-occurring with autism in adults: The Autism Depression Trial (ADEPT) - a pilot randomised controlled trial / Ailsa RUSSELL in Autism, 24-6 (August 2020)
PermalinkTrajectories of autistic social traits in childhood and adolescence and disordered eating behaviours at age 14 years: A UK general population cohort study / Francesca SOLMI in Journal of Child Psychology and Psychiatry, 62-1 (January 2021)
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