Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Autism Research . 12-12Paru le : 01/12/2019 |
[n° ou bulletin]
[n° ou bulletin]
12-12 - December [Texte imprimé et/ou numérique] . - 2019. Langues : Anglais (eng)
|
Exemplaires (1)
Code-barres | Cote | Support | Localisation | Section | Disponibilité |
---|---|---|---|---|---|
PER0001783 | PER ARE | Périodique | Centre d'Information et de Documentation du CRA Rhône-Alpes | PER - Périodiques | Exclu du prêt |
Dépouillements
Ajouter le résultat dans votre panierAdditional psychometric properties of the WHODAS-II in individuals with autism spectrum disorder / Z. J. WILLIAMS in Autism Research, 12-12 (December)
[article]
Titre : Additional psychometric properties of the WHODAS-II in individuals with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Z. J. WILLIAMS, Auteur Année de publication : 2019 Article en page(s) : p.1724-1725 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2215 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1724-1725[article] Additional psychometric properties of the WHODAS-II in individuals with autism spectrum disorder [Texte imprimé et/ou numérique] / Z. J. WILLIAMS, Auteur . - 2019 . - p.1724-1725.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1724-1725
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2215 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Replication of the psychometric properties of the WHODAS-II in individuals with autism spectrum disorder / S. H. PARK in Autism Research, 12-12 (December)
[article]
Titre : Replication of the psychometric properties of the WHODAS-II in individuals with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : S. H. PARK, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; Y. J. C. SONG, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur Année de publication : 2019 Article en page(s) : p.1726-1727 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2216 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1726-1727[article] Replication of the psychometric properties of the WHODAS-II in individuals with autism spectrum disorder [Texte imprimé et/ou numérique] / S. H. PARK, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; Y. J. C. SONG, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur . - 2019 . - p.1726-1727.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1726-1727
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2216 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 VariCarta: A Comprehensive Database of Harmonized Genomic Variants Found in Autism Spectrum Disorder Sequencing Studies / M. BELMADANI in Autism Research, 12-12 (December)
[article]
Titre : VariCarta: A Comprehensive Database of Harmonized Genomic Variants Found in Autism Spectrum Disorder Sequencing Studies Type de document : Texte imprimé et/ou numérique Auteurs : M. BELMADANI, Auteur ; M. JACOBSON, Auteur ; N. HOLMES, Auteur ; M. PHAN, Auteur ; T. NGUYEN, Auteur ; P. PAVLIDIS, Auteur ; S. ROGIC, Auteur Année de publication : 2019 Article en page(s) : p.1728-1736 Langues : Anglais (eng) Mots-clés : ASD variants variant annotation variant curation variant database variant harmonization Index. décimale : PER Périodiques Résumé : Recent years have seen a boom in the application of the next-generation sequencing technology to the study of human disorders, including Autism Spectrum Disorder (ASD), where the focus has been on identifying rare, possibly causative genomic variants in ASD individuals. Because of the high genetic heterogeneity of ASD, a large number of subjects is needed to establish evidence for a variant or gene ASD-association, thus aggregating data across cohorts and studies is necessary. However, methodological inconsistencies and subject overlap across studies complicate data aggregation. Here we present VariCarta, a web-based database developed to address these challenges by collecting, reconciling, and consistently cataloging literature-derived genomic variants found in ASD subjects using ongoing semi-manual curation. The careful manual curation combined with a robust data import pipeline rectifies errors, converts variants into a standardized format, identifies and harmonizes cohort overlaps, and documents data provenance. The harmonization aspect is especially important since it prevents the potential double counting of variants, which can lead to inflation of gene-based evidence for ASD-association. The database currently contains 170,416 variant events from 10,893 subjects, collected across 61 publications, and reconciles 16,202 variants that have been reported in literature multiple times. VariCarta is freely accessible at http://varicarta.msl.ubc.ca. Autism Res 2019, 12: 1728-1736. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: The search for genetic factors underlying Autism Spectrum Disorder (ASD) yielded numerous studies reporting potentially causative genomic variants found in ASD individuals. However, methodological differences and subject overlap across studies complicate the assembly of these data, diminishing its utility and accessibility. We developed VariCarta, a web-based database that aggregates carefully curated, annotated, and harmonized literature-derived variants identified in individuals with ASD using ongoing semi-manual curation. En ligne : http://dx.doi.org/10.1002/aur.2236 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1728-1736[article] VariCarta: A Comprehensive Database of Harmonized Genomic Variants Found in Autism Spectrum Disorder Sequencing Studies [Texte imprimé et/ou numérique] / M. BELMADANI, Auteur ; M. JACOBSON, Auteur ; N. HOLMES, Auteur ; M. PHAN, Auteur ; T. NGUYEN, Auteur ; P. PAVLIDIS, Auteur ; S. ROGIC, Auteur . - 2019 . - p.1728-1736.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1728-1736
Mots-clés : ASD variants variant annotation variant curation variant database variant harmonization Index. décimale : PER Périodiques Résumé : Recent years have seen a boom in the application of the next-generation sequencing technology to the study of human disorders, including Autism Spectrum Disorder (ASD), where the focus has been on identifying rare, possibly causative genomic variants in ASD individuals. Because of the high genetic heterogeneity of ASD, a large number of subjects is needed to establish evidence for a variant or gene ASD-association, thus aggregating data across cohorts and studies is necessary. However, methodological inconsistencies and subject overlap across studies complicate data aggregation. Here we present VariCarta, a web-based database developed to address these challenges by collecting, reconciling, and consistently cataloging literature-derived genomic variants found in ASD subjects using ongoing semi-manual curation. The careful manual curation combined with a robust data import pipeline rectifies errors, converts variants into a standardized format, identifies and harmonizes cohort overlaps, and documents data provenance. The harmonization aspect is especially important since it prevents the potential double counting of variants, which can lead to inflation of gene-based evidence for ASD-association. The database currently contains 170,416 variant events from 10,893 subjects, collected across 61 publications, and reconciles 16,202 variants that have been reported in literature multiple times. VariCarta is freely accessible at http://varicarta.msl.ubc.ca. Autism Res 2019, 12: 1728-1736. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: The search for genetic factors underlying Autism Spectrum Disorder (ASD) yielded numerous studies reporting potentially causative genomic variants found in ASD individuals. However, methodological differences and subject overlap across studies complicate the assembly of these data, diminishing its utility and accessibility. We developed VariCarta, a web-based database that aggregates carefully curated, annotated, and harmonized literature-derived variants identified in individuals with ASD using ongoing semi-manual curation. En ligne : http://dx.doi.org/10.1002/aur.2236 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Interrelationship Between Cognitive Control, Anxiety, and Restricted and Repetitive Behaviors in Children with 22q11.2 Deletion Syndrome / M. ULJAREVIC in Autism Research, 12-12 (December)
[article]
Titre : Interrelationship Between Cognitive Control, Anxiety, and Restricted and Repetitive Behaviors in Children with 22q11.2 Deletion Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : M. ULJAREVIC, Auteur ; K. L. MCCABE, Auteur ; Kathleen ANGKUSTSIRI, Auteur ; T. J. SIMON, Auteur ; A. Y. HARDAN, Auteur Année de publication : 2019 Article en page(s) : p.1737-1744 Langues : Anglais (eng) Mots-clés : 22q11.2DS anxiety cognitive control repetitive behaviors Index. décimale : PER Périodiques Résumé : Restricted and repetitive behaviors (RRB) are common in individuals with 22q11.2 microdeletion syndrome (22q11.2DS), yet the underlying mechanisms of these behaviors remain poorly characterized. In the present pilot investigation, we aimed to further our understanding of RRB in 22q11.2DS by exploring their relationship with cognitive control and anxiety as well as with sex, chronological age, and full-scale IQ. Parents of 38 children with 22q11.2DS (17 females; Mage = 11.15 years, SD = 2.46) completed the Social Communication Questionnaire as a measure of RRB and social and communication (SC) problems and the Behavioral Assessment System for Children-2 as a measure of anxiety and cognitive control. Higher RRB scores were significantly associated with higher anxiety levels (r = 0.44, P = 0.006), more impairments in cognitive control (r = 0.56, P < 0.001), and higher SC scores (r = 0.43, P = 0.011). In the first step of the hierarchical regression model, anxiety accounted for 24.5% of variance (F = 10.05, P = 0.003); cognitive control accounted for an additional 18.1% of variance (Fchange = 11.15, P < 0.001) in the second step; SC score accounted for only 0.8% of additional variance in the third step (Fchange = 0.40, P = 0.53). The final model explained 43.4% of variance (F = 7.42, P = 0.001), with cognitive control as a unique independent predictor of RRB score (t = 2.52, P = 0.01). The current study provides the first exploration of the cognitive control-anxiety-RRB link in individuals with 22q11.2DS and points to cognitive control as a potentially viable target for treatments aimed at reducing RRB. Autism Res 2019, 12: 1737-1744. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: People with 22q11.2 deletion syndrome show high levels of repetitive behaviors, however, the previous research has not explored why people with this syndrome exhibit high rates of repetitive behaviors. Understanding the reasons for the high levels of repetitive behaviors is important given that these behaviors can be highly impairing. Our study found that repetitive behaviors were associated with impaired ability to self-regulate and high levels of anxiety. These findings need to be further replicated; however, they are important as they suggest potentially promising ways of reducing these behaviors. En ligne : http://dx.doi.org/10.1002/aur.2194 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1737-1744[article] Interrelationship Between Cognitive Control, Anxiety, and Restricted and Repetitive Behaviors in Children with 22q11.2 Deletion Syndrome [Texte imprimé et/ou numérique] / M. ULJAREVIC, Auteur ; K. L. MCCABE, Auteur ; Kathleen ANGKUSTSIRI, Auteur ; T. J. SIMON, Auteur ; A. Y. HARDAN, Auteur . - 2019 . - p.1737-1744.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1737-1744
Mots-clés : 22q11.2DS anxiety cognitive control repetitive behaviors Index. décimale : PER Périodiques Résumé : Restricted and repetitive behaviors (RRB) are common in individuals with 22q11.2 microdeletion syndrome (22q11.2DS), yet the underlying mechanisms of these behaviors remain poorly characterized. In the present pilot investigation, we aimed to further our understanding of RRB in 22q11.2DS by exploring their relationship with cognitive control and anxiety as well as with sex, chronological age, and full-scale IQ. Parents of 38 children with 22q11.2DS (17 females; Mage = 11.15 years, SD = 2.46) completed the Social Communication Questionnaire as a measure of RRB and social and communication (SC) problems and the Behavioral Assessment System for Children-2 as a measure of anxiety and cognitive control. Higher RRB scores were significantly associated with higher anxiety levels (r = 0.44, P = 0.006), more impairments in cognitive control (r = 0.56, P < 0.001), and higher SC scores (r = 0.43, P = 0.011). In the first step of the hierarchical regression model, anxiety accounted for 24.5% of variance (F = 10.05, P = 0.003); cognitive control accounted for an additional 18.1% of variance (Fchange = 11.15, P < 0.001) in the second step; SC score accounted for only 0.8% of additional variance in the third step (Fchange = 0.40, P = 0.53). The final model explained 43.4% of variance (F = 7.42, P = 0.001), with cognitive control as a unique independent predictor of RRB score (t = 2.52, P = 0.01). The current study provides the first exploration of the cognitive control-anxiety-RRB link in individuals with 22q11.2DS and points to cognitive control as a potentially viable target for treatments aimed at reducing RRB. Autism Res 2019, 12: 1737-1744. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: People with 22q11.2 deletion syndrome show high levels of repetitive behaviors, however, the previous research has not explored why people with this syndrome exhibit high rates of repetitive behaviors. Understanding the reasons for the high levels of repetitive behaviors is important given that these behaviors can be highly impairing. Our study found that repetitive behaviors were associated with impaired ability to self-regulate and high levels of anxiety. These findings need to be further replicated; however, they are important as they suggest potentially promising ways of reducing these behaviors. En ligne : http://dx.doi.org/10.1002/aur.2194 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Visual and Proprioceptive Influences on Tactile Spatial Processing in Adults with Autism Spectrum Disorders / M. HENSE in Autism Research, 12-12 (December)
[article]
Titre : Visual and Proprioceptive Influences on Tactile Spatial Processing in Adults with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : M. HENSE, Auteur ; S. BADDE, Auteur ; S. KOHNE, Auteur ; I. DZIOBEK, Auteur ; B. RODER, Auteur Année de publication : 2019 Article en page(s) : p.1745-1757 Langues : Anglais (eng) Mots-clés : adult autism spectrum disorder multisensory integration posture spatial processing touch Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders (ASDs) often exhibit altered representations of the external world. Consistently, when localizing touch, children with ASDs were less influenced than their peers by changes of the stimulated limb's location in external space [Wada et al., Scientific Reports 2015, 4(1), 5985]. However, given the protracted development of an external-spatial dominance in tactile processing in typically developing children, this difference might reflect a developmental delay rather than a set suppression of external space in ASDs. Here, adults with ASDs and matched control-participants completed (a) the tactile temporal order judgment (TOJ) task previously used to test external-spatial representation of touch in children with ASDs and (b) a tactile-visual cross-modal congruency (CC) task which assesses benefits of task-irrelevant visual stimuli on tactile localization in external space. In both experiments, participants localized tactile stimuli to the fingers of each hand, while holding their hands either crossed or uncrossed. Performance differences between hand postures reflect the influence of external-spatial codes. In both groups, tactile TOJ-performance markedly decreased when participants crossed their hands and CC-effects were especially large if the visual stimulus was presented at the same side of external space as the task-relevant touch. The absence of group differences was statistically confirmed using Bayesian statistical modeling: adults with ASDs weighted external-spatial codes comparable to typically developed adults during tactile and visual-tactile spatio-temporal tasks. Thus, atypicalities in the spatial coding of touch for children with ASDs appear to reflect a developmental delay rather than a stable characteristic of ASD. Autism Res 2019, 12: 1745-1757. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: A touched limb's location can be described twofold, with respect to the body (right hand) or the external world (right side). Children and adolescents with autism spectrum disorder (ASD) reportedly rely less than their peers on the external world. Here, adults with and without ASDs completed two tactile localization tasks. Both groups relied to the same degree on external world locations. This opens the possibility that the tendency to relate touch to the external world is typical in individuals with ASDs but emerges with a delay. En ligne : http://dx.doi.org/10.1002/aur.2202 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1745-1757[article] Visual and Proprioceptive Influences on Tactile Spatial Processing in Adults with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / M. HENSE, Auteur ; S. BADDE, Auteur ; S. KOHNE, Auteur ; I. DZIOBEK, Auteur ; B. RODER, Auteur . - 2019 . - p.1745-1757.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1745-1757
Mots-clés : adult autism spectrum disorder multisensory integration posture spatial processing touch Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders (ASDs) often exhibit altered representations of the external world. Consistently, when localizing touch, children with ASDs were less influenced than their peers by changes of the stimulated limb's location in external space [Wada et al., Scientific Reports 2015, 4(1), 5985]. However, given the protracted development of an external-spatial dominance in tactile processing in typically developing children, this difference might reflect a developmental delay rather than a set suppression of external space in ASDs. Here, adults with ASDs and matched control-participants completed (a) the tactile temporal order judgment (TOJ) task previously used to test external-spatial representation of touch in children with ASDs and (b) a tactile-visual cross-modal congruency (CC) task which assesses benefits of task-irrelevant visual stimuli on tactile localization in external space. In both experiments, participants localized tactile stimuli to the fingers of each hand, while holding their hands either crossed or uncrossed. Performance differences between hand postures reflect the influence of external-spatial codes. In both groups, tactile TOJ-performance markedly decreased when participants crossed their hands and CC-effects were especially large if the visual stimulus was presented at the same side of external space as the task-relevant touch. The absence of group differences was statistically confirmed using Bayesian statistical modeling: adults with ASDs weighted external-spatial codes comparable to typically developed adults during tactile and visual-tactile spatio-temporal tasks. Thus, atypicalities in the spatial coding of touch for children with ASDs appear to reflect a developmental delay rather than a stable characteristic of ASD. Autism Res 2019, 12: 1745-1757. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: A touched limb's location can be described twofold, with respect to the body (right hand) or the external world (right side). Children and adolescents with autism spectrum disorder (ASD) reportedly rely less than their peers on the external world. Here, adults with and without ASDs completed two tactile localization tasks. Both groups relied to the same degree on external world locations. This opens the possibility that the tendency to relate touch to the external world is typical in individuals with ASDs but emerges with a delay. En ligne : http://dx.doi.org/10.1002/aur.2202 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complex / A. DICKINSON in Autism Research, 12-12 (December)
[article]
Titre : Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complex Type de document : Texte imprimé et/ou numérique Auteurs : A. DICKINSON, Auteur ; Kandice J. VARCIN, Auteur ; M. SAHIN, Auteur ; C. A. NELSON, Auteur ; S. S. JESTE, Auteur Année de publication : 2019 Article en page(s) : p.1758-1773 Langues : Anglais (eng) Mots-clés : alpha oscillations autism spectrum disorder cognitive function electroencephalography functional connectivity infancy tuberous sclerosis complex Index. décimale : PER Périodiques Résumé : Tuberous sclerosis complex (TSC) is a rare genetic disorder that confers a high risk for autism spectrum disorders (ASD), with behavioral predictors of ASD emerging early in life. Deviations in structural and functional neural connectivity are highly implicated in both TSC and ASD. For the first time, we explore whether electroencephalographic (EEG) measures of neural network function precede or predict the emergence of ASD in TSC. We determine whether altered brain function (a) is present in infancy in TSC, (b) differentiates infants with TSC based on ASD diagnostic status, and (c) is associated with later cognitive function. We studied 35 infants with TSC (N = 35), and a group of typically developing infants (N = 20) at 12 and 24 months of age. Infants with TSC were later subdivided into ASD and non-ASD groups based on clinical evaluation. We measured features of spontaneous alpha oscillations (6-12 Hz) that are closely associated with neural network development: alpha power, alpha phase coherence (APC), and peak alpha frequency (PAF). Infants with TSC demonstrated reduced interhemispheric APC compared to controls at 12 months of age, and these differences were found to be most pronounced at 24 months in the infants who later developed ASD. Across all infants, PAF at 24 months was associated with verbal and nonverbal cognition at 36 months. Associations between early network function and later neurodevelopmental and cognitive outcomes highlight the potential utility of early scalable EEG markers to identify infants with TSC requiring additional targeted intervention initiated very early in life. Autism Res 2019, 12: 1758-1773. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Approximately half of infants with tuberous sclerosis complex (TSC) develop autism. Here, using EEG, we find that there is a reduction in communication between brain regions during infancy in TSC, and that the infants who show the largest reductions are those who later develop autism. Being able to identify infants who show early signs of disrupted brain development may improve the timing of early prediction and interventions in TSC, and also help us to understand how early brain changes lead to autism. En ligne : http://dx.doi.org/10.1002/aur.2193 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1758-1773[article] Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complex [Texte imprimé et/ou numérique] / A. DICKINSON, Auteur ; Kandice J. VARCIN, Auteur ; M. SAHIN, Auteur ; C. A. NELSON, Auteur ; S. S. JESTE, Auteur . - 2019 . - p.1758-1773.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1758-1773
Mots-clés : alpha oscillations autism spectrum disorder cognitive function electroencephalography functional connectivity infancy tuberous sclerosis complex Index. décimale : PER Périodiques Résumé : Tuberous sclerosis complex (TSC) is a rare genetic disorder that confers a high risk for autism spectrum disorders (ASD), with behavioral predictors of ASD emerging early in life. Deviations in structural and functional neural connectivity are highly implicated in both TSC and ASD. For the first time, we explore whether electroencephalographic (EEG) measures of neural network function precede or predict the emergence of ASD in TSC. We determine whether altered brain function (a) is present in infancy in TSC, (b) differentiates infants with TSC based on ASD diagnostic status, and (c) is associated with later cognitive function. We studied 35 infants with TSC (N = 35), and a group of typically developing infants (N = 20) at 12 and 24 months of age. Infants with TSC were later subdivided into ASD and non-ASD groups based on clinical evaluation. We measured features of spontaneous alpha oscillations (6-12 Hz) that are closely associated with neural network development: alpha power, alpha phase coherence (APC), and peak alpha frequency (PAF). Infants with TSC demonstrated reduced interhemispheric APC compared to controls at 12 months of age, and these differences were found to be most pronounced at 24 months in the infants who later developed ASD. Across all infants, PAF at 24 months was associated with verbal and nonverbal cognition at 36 months. Associations between early network function and later neurodevelopmental and cognitive outcomes highlight the potential utility of early scalable EEG markers to identify infants with TSC requiring additional targeted intervention initiated very early in life. Autism Res 2019, 12: 1758-1773. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Approximately half of infants with tuberous sclerosis complex (TSC) develop autism. Here, using EEG, we find that there is a reduction in communication between brain regions during infancy in TSC, and that the infants who show the largest reductions are those who later develop autism. Being able to identify infants who show early signs of disrupted brain development may improve the timing of early prediction and interventions in TSC, and also help us to understand how early brain changes lead to autism. En ligne : http://dx.doi.org/10.1002/aur.2193 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Increased facial asymmetry in autism spectrum conditions is associated with symptom presentation / Maryam BOUTRUS in Autism Research, 12-12 (December)
[article]
Titre : Increased facial asymmetry in autism spectrum conditions is associated with symptom presentation Type de document : Texte imprimé et/ou numérique Auteurs : Maryam BOUTRUS, Auteur ; S. Z. GILANI, Auteur ; Gail A. ALVARES, Auteur ; M. T. MAYBERY, Auteur ; D. W. TAN, Auteur ; A. MIAN, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Année de publication : 2019 Article en page(s) : p.1774-1783 Langues : Anglais (eng) Mots-clés : autism facial asymmetry morphology neurodevelopment subgroups Index. décimale : PER Périodiques Résumé : A key research priority in the study of autism spectrum conditions (ASC) is the discovery of biological markers that may help to identify and elucidate etiologically distinct subgroups. One physical marker that has received increasing research attention is facial structure. Although there remains little consensus in the field, findings relating to greater facial asymmetry (FA) in ASC exhibit some consistency. As there is growing recognition of the importance of replicatory studies in ASC research, the aim of this study was to investigate the replicability of increased FA in autistic children compared to nonautistic peers. Using three-dimensional photogrammetry, this study examined FA in 84 autistic children, 110 typically developing children with no family history of the condition, and 49 full siblings of autistic children. In support of previous literature, significantly greater depth-wise FA was identified in autistic children relative to the two comparison groups. As a further investigation, increased lateral FA in autistic children was found to be associated with greater severity of ASC symptoms on the Autism Diagnostic Observation Schedule, second edition, specifically related to repetitive and restrictive behaviors. These outcomes provide an important and independent replication of increased FA in ASC, as well as a novel contribution to the field. Having confirmed the direction and areas of increased FA in ASC, these findings could motivate a search for potential underlying brain dysmorphogenesis. Autism Res 2019, 12: 1774-1783. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study looked at the amount of facial asymmetry (FA) in autistic children compared to typically developing children and children who have siblings with autism. The study found that autistic children, compared to the other two groups, had greater FA, and that increased FA was related to greater severity of autistic symptoms. The face and brain grow together during the earliest stages of development, and so findings of facial differences in autism might inform future studies of early brain differences associated with the condition. En ligne : http://dx.doi.org/10.1002/aur.2161 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1774-1783[article] Increased facial asymmetry in autism spectrum conditions is associated with symptom presentation [Texte imprimé et/ou numérique] / Maryam BOUTRUS, Auteur ; S. Z. GILANI, Auteur ; Gail A. ALVARES, Auteur ; M. T. MAYBERY, Auteur ; D. W. TAN, Auteur ; A. MIAN, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - 2019 . - p.1774-1783.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1774-1783
Mots-clés : autism facial asymmetry morphology neurodevelopment subgroups Index. décimale : PER Périodiques Résumé : A key research priority in the study of autism spectrum conditions (ASC) is the discovery of biological markers that may help to identify and elucidate etiologically distinct subgroups. One physical marker that has received increasing research attention is facial structure. Although there remains little consensus in the field, findings relating to greater facial asymmetry (FA) in ASC exhibit some consistency. As there is growing recognition of the importance of replicatory studies in ASC research, the aim of this study was to investigate the replicability of increased FA in autistic children compared to nonautistic peers. Using three-dimensional photogrammetry, this study examined FA in 84 autistic children, 110 typically developing children with no family history of the condition, and 49 full siblings of autistic children. In support of previous literature, significantly greater depth-wise FA was identified in autistic children relative to the two comparison groups. As a further investigation, increased lateral FA in autistic children was found to be associated with greater severity of ASC symptoms on the Autism Diagnostic Observation Schedule, second edition, specifically related to repetitive and restrictive behaviors. These outcomes provide an important and independent replication of increased FA in ASC, as well as a novel contribution to the field. Having confirmed the direction and areas of increased FA in ASC, these findings could motivate a search for potential underlying brain dysmorphogenesis. Autism Res 2019, 12: 1774-1783. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study looked at the amount of facial asymmetry (FA) in autistic children compared to typically developing children and children who have siblings with autism. The study found that autistic children, compared to the other two groups, had greater FA, and that increased FA was related to greater severity of autistic symptoms. The face and brain grow together during the earliest stages of development, and so findings of facial differences in autism might inform future studies of early brain differences associated with the condition. En ligne : http://dx.doi.org/10.1002/aur.2161 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Early language exposure supports later language skills in infants with and without autism / M. R. SWANSON in Autism Research, 12-12 (December)
[article]
Titre : Early language exposure supports later language skills in infants with and without autism Type de document : Texte imprimé et/ou numérique Auteurs : M. R. SWANSON, Auteur ; K. DONOVAN, Auteur ; S. PATERSON, Auteur ; J. J. WOLFF, Auteur ; Julia PARISH-MORRIS, Auteur ; S. S. MEERA, Auteur ; Linda R. WATSON, Auteur ; A. M. ESTES, Auteur ; N. MARRUS, Auteur ; J. T. ELISON, Auteur ; M. D. SHEN, Auteur ; H. B. MCNEILLY, Auteur ; L. MACINTYRE, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; T. ST JOHN, Auteur ; Kelly N. BOTTERON, Auteur ; Stephen R. DAGER, Auteur ; J. PIVEN, Auteur Année de publication : 2019 Article en page(s) : p.1784-1795 Langues : Anglais (eng) Mots-clés : Asd caregiver speech high familial risk home language environment infancy language socioeconomic status Index. décimale : PER Périodiques Résumé : The way that parents communicate with their typically developing infants is associated with later infant language development. Here we aim to show that these associations are observed in infants subsequently diagnosed with autism spectrum disorder (ASD). This study had three groups: high-familial-risk infants who did not have ASD (n = 46); high-familial-risk infants who had ASD (n = 14); and low-familial-risk infants who exhibited typical development (n = 36). All-day home language recordings were collected at 9 and 15 months, and language skills were assessed at 24 months. Across all infants in the study, including those with ASD, a richer home language environment (e.g., hearing more adult words and experiencing more conversational turns) at 9 and 15 months was associated with better language skills. Higher parental educational attainment was associated with a richer home language environment. Mediation analyses showed that the effect of education on child language skills was explained by the richness of the home language environment. Exploratory analyses revealed that typically developing infants experience an increase in caregiver-child conversational turns across 9-15 months, a pattern not seen in children with ASD. The current study shows that parent behavior during the earliest stages of life can have a significant impact on later development, highlighting the home language environment as means to support development in infants with ASD. Autism Res 2019, 12: 1784-1795. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: It has long been understood that caregiver speech supports language skills in typically developing infants. In this study, parents of infants who were later diagnosed with ASD and parents of infants in the control groups completed all-day home language recordings. We found that for all infants in our study, those who heard more caregiver speech had better language skills later in life. Parental education level was also related to how much caregiver speech an infant experienced. En ligne : http://dx.doi.org/10.1002/aur.2163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1784-1795[article] Early language exposure supports later language skills in infants with and without autism [Texte imprimé et/ou numérique] / M. R. SWANSON, Auteur ; K. DONOVAN, Auteur ; S. PATERSON, Auteur ; J. J. WOLFF, Auteur ; Julia PARISH-MORRIS, Auteur ; S. S. MEERA, Auteur ; Linda R. WATSON, Auteur ; A. M. ESTES, Auteur ; N. MARRUS, Auteur ; J. T. ELISON, Auteur ; M. D. SHEN, Auteur ; H. B. MCNEILLY, Auteur ; L. MACINTYRE, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; T. ST JOHN, Auteur ; Kelly N. BOTTERON, Auteur ; Stephen R. DAGER, Auteur ; J. PIVEN, Auteur . - 2019 . - p.1784-1795.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1784-1795
Mots-clés : Asd caregiver speech high familial risk home language environment infancy language socioeconomic status Index. décimale : PER Périodiques Résumé : The way that parents communicate with their typically developing infants is associated with later infant language development. Here we aim to show that these associations are observed in infants subsequently diagnosed with autism spectrum disorder (ASD). This study had three groups: high-familial-risk infants who did not have ASD (n = 46); high-familial-risk infants who had ASD (n = 14); and low-familial-risk infants who exhibited typical development (n = 36). All-day home language recordings were collected at 9 and 15 months, and language skills were assessed at 24 months. Across all infants in the study, including those with ASD, a richer home language environment (e.g., hearing more adult words and experiencing more conversational turns) at 9 and 15 months was associated with better language skills. Higher parental educational attainment was associated with a richer home language environment. Mediation analyses showed that the effect of education on child language skills was explained by the richness of the home language environment. Exploratory analyses revealed that typically developing infants experience an increase in caregiver-child conversational turns across 9-15 months, a pattern not seen in children with ASD. The current study shows that parent behavior during the earliest stages of life can have a significant impact on later development, highlighting the home language environment as means to support development in infants with ASD. Autism Res 2019, 12: 1784-1795. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: It has long been understood that caregiver speech supports language skills in typically developing infants. In this study, parents of infants who were later diagnosed with ASD and parents of infants in the control groups completed all-day home language recordings. We found that for all infants in our study, those who heard more caregiver speech had better language skills later in life. Parental education level was also related to how much caregiver speech an infant experienced. En ligne : http://dx.doi.org/10.1002/aur.2163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Spontaneous helping behavior of autistic and non-autistic (Pre-)adolescents: A matter of motivation? / R. A. G. O'CONNOR in Autism Research, 12-12 (December)
[article]
Titre : Spontaneous helping behavior of autistic and non-autistic (Pre-)adolescents: A matter of motivation? Type de document : Texte imprimé et/ou numérique Auteurs : R. A. G. O'CONNOR, Auteur ; L. STOCKMANN, Auteur ; C. RIEFFE, Auteur Année de publication : 2019 Article en page(s) : p.1796-1804 Langues : Anglais (eng) Mots-clés : autism gender helping pro-social social motivation Index. décimale : PER Périodiques Résumé : Young autistic people have a range of social difficulties, but it is not yet clear how these difficulties can be explained. In addition, emerging research is suggesting that autistic girls may differ from boys in terms of their social behaviors, but yet unknown is if they differ in terms of their pro-social behavior, such as helping. The present study investigated spontaneous helping behavior using an in vivo paradigm and related this to participants' levels of social motivation (based on parent reports). Participants were 233 autistic and non-autistic (pre-)adolescents (M = 12.46 years, SD = 15.54 months). Our results demonstrated that autistic girls and boys have lower levels of social motivation compared to their non-autistic peers, but social motivation was unrelated to helping behavior in both groups. Furthermore, when the experimenter needed help, the autistic boys and girls looked and smiled to the same extent as their peers of the same gender, but they actually helped significantly less than their non-autistic peers. However, most autistic youngsters did help, highlighting the great individual differences in autistic individuals. We discuss the possibility that lower levels of helping behavior are due to difficulty initiating action in a social context, rather than lower social motivation. Autism Res 2019, 12: 1796-1804. (c) 2019 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: This study examined the helping behavior of autistic boys and girls (aged 9-16). Many autistic young people did help, but compared to non-autistic individuals, autistic people did not help as much. This study also showed that when people did/did not help, it was not related to their interest in social relationships. It is important to teach young autistic people when and how to help others, to support them making friends. En ligne : http://dx.doi.org/10.1002/aur.2182 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1796-1804[article] Spontaneous helping behavior of autistic and non-autistic (Pre-)adolescents: A matter of motivation? [Texte imprimé et/ou numérique] / R. A. G. O'CONNOR, Auteur ; L. STOCKMANN, Auteur ; C. RIEFFE, Auteur . - 2019 . - p.1796-1804.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1796-1804
Mots-clés : autism gender helping pro-social social motivation Index. décimale : PER Périodiques Résumé : Young autistic people have a range of social difficulties, but it is not yet clear how these difficulties can be explained. In addition, emerging research is suggesting that autistic girls may differ from boys in terms of their social behaviors, but yet unknown is if they differ in terms of their pro-social behavior, such as helping. The present study investigated spontaneous helping behavior using an in vivo paradigm and related this to participants' levels of social motivation (based on parent reports). Participants were 233 autistic and non-autistic (pre-)adolescents (M = 12.46 years, SD = 15.54 months). Our results demonstrated that autistic girls and boys have lower levels of social motivation compared to their non-autistic peers, but social motivation was unrelated to helping behavior in both groups. Furthermore, when the experimenter needed help, the autistic boys and girls looked and smiled to the same extent as their peers of the same gender, but they actually helped significantly less than their non-autistic peers. However, most autistic youngsters did help, highlighting the great individual differences in autistic individuals. We discuss the possibility that lower levels of helping behavior are due to difficulty initiating action in a social context, rather than lower social motivation. Autism Res 2019, 12: 1796-1804. (c) 2019 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: This study examined the helping behavior of autistic boys and girls (aged 9-16). Many autistic young people did help, but compared to non-autistic individuals, autistic people did not help as much. This study also showed that when people did/did not help, it was not related to their interest in social relationships. It is important to teach young autistic people when and how to help others, to support them making friends. En ligne : http://dx.doi.org/10.1002/aur.2182 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Sympathetic-Parasympathetic Interaction and Externalizing Problems in Children with Autism Spectrum Disorder / R. M. FENNING in Autism Research, 12-12 (December)
[article]
Titre : Sympathetic-Parasympathetic Interaction and Externalizing Problems in Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : R. M. FENNING, Auteur ; S. A. ERATH, Auteur ; J. K. BAKER, Auteur ; D. S. MESSINGER, Auteur ; J. MOFFITT, Auteur ; Brian R. BAUCOM, Auteur ; A. K. KAEPPLER, Auteur Année de publication : 2019 Article en page(s) : p.1805-1816 Langues : Anglais (eng) Mots-clés : autism spectrum disorder autonomic nervous system electrodermal activity emotion regulation externalizing behavior problems psychophysiology respiratory sinus arrhythmia Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) exhibit significant difficulties with emotion regulation and reactivity, which may be linked to underlying psychophysiology. The present study examined associations between autonomic nervous system activity and individual differences in externalizing behavior problems in children with ASD. A multisystem approach was adopted to consider the interplay between markers of sympathetic (electrodermal reactivity-EDA-R) and parasympathetic reactivity (respiratory sinus arrhythmia reactivity-RSA-R) in relation to behavioral challenges. Fifty-two children with ASD ages 6-10 years contributed complete psychophysiological data. Measures of EDA-R and RSA-R (RSA withdrawal) were obtained in response to a laboratory challenge task and parents reported on child externalizing behavior problems using a standardized questionnaire and a structured clinical interview. An equifinality model was supported, with two distinct psychophysiological pathways linked to heightened externalizing behavior problems. Greater RSA-R was associated with more externalizing problems in the context of higher levels of EDA-R, and lower EDA-R was associated with increased externalizing problems at lower levels of RSA-R. Findings underscore the importance of considering the role of psychophysiology in the unfolding of comorbid externalizing problems in children with ASD. Potential implications for tailoring coregulatory supports are discussed. Autism Res 2019, 12: 1805-1816. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Children with autism spectrum disorder (ASD) exhibit elevated rates of challenging behavior. This study identified specific psychophysiological profiles (low sympathetic-low parasympathetic reactivity, and high sympathetic-high parasympathetic reactivity) that may place these children at greater risk for behavior problems. Findings have implications for better understanding behavioral challenges in children with ASD, and for tailoring supports to address underlying psychophysiology. En ligne : http://dx.doi.org/10.1002/aur.2187 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1805-1816[article] Sympathetic-Parasympathetic Interaction and Externalizing Problems in Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / R. M. FENNING, Auteur ; S. A. ERATH, Auteur ; J. K. BAKER, Auteur ; D. S. MESSINGER, Auteur ; J. MOFFITT, Auteur ; Brian R. BAUCOM, Auteur ; A. K. KAEPPLER, Auteur . - 2019 . - p.1805-1816.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1805-1816
Mots-clés : autism spectrum disorder autonomic nervous system electrodermal activity emotion regulation externalizing behavior problems psychophysiology respiratory sinus arrhythmia Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) exhibit significant difficulties with emotion regulation and reactivity, which may be linked to underlying psychophysiology. The present study examined associations between autonomic nervous system activity and individual differences in externalizing behavior problems in children with ASD. A multisystem approach was adopted to consider the interplay between markers of sympathetic (electrodermal reactivity-EDA-R) and parasympathetic reactivity (respiratory sinus arrhythmia reactivity-RSA-R) in relation to behavioral challenges. Fifty-two children with ASD ages 6-10 years contributed complete psychophysiological data. Measures of EDA-R and RSA-R (RSA withdrawal) were obtained in response to a laboratory challenge task and parents reported on child externalizing behavior problems using a standardized questionnaire and a structured clinical interview. An equifinality model was supported, with two distinct psychophysiological pathways linked to heightened externalizing behavior problems. Greater RSA-R was associated with more externalizing problems in the context of higher levels of EDA-R, and lower EDA-R was associated with increased externalizing problems at lower levels of RSA-R. Findings underscore the importance of considering the role of psychophysiology in the unfolding of comorbid externalizing problems in children with ASD. Potential implications for tailoring coregulatory supports are discussed. Autism Res 2019, 12: 1805-1816. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Children with autism spectrum disorder (ASD) exhibit elevated rates of challenging behavior. This study identified specific psychophysiological profiles (low sympathetic-low parasympathetic reactivity, and high sympathetic-high parasympathetic reactivity) that may place these children at greater risk for behavior problems. Findings have implications for better understanding behavioral challenges in children with ASD, and for tailoring supports to address underlying psychophysiology. En ligne : http://dx.doi.org/10.1002/aur.2187 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Process research in early intensive intervention in autism spectrum disorder: Sensitivity to change of the autism behavior coding system / E. HERBRECHT in Autism Research, 12-12 (December)
[article]
Titre : Process research in early intensive intervention in autism spectrum disorder: Sensitivity to change of the autism behavior coding system Type de document : Texte imprimé et/ou numérique Auteurs : E. HERBRECHT, Auteur ; O. LAZARI, Auteur ; M. NOTTER, Auteur ; K. SCHMECK, Auteur ; R. SPIEGEL, Auteur Année de publication : 2019 Article en page(s) : p.1817-1828 Langues : Anglais (eng) Mots-clés : Abcs autism spectrum disorder early intensive intervention process research sensitivity to change Index. décimale : PER Périodiques Résumé : The development of sensitive measures to capture changes in core autism symptoms is crucial in early intervention research. The study examines the sensitivity to change of the Autism Behavior Coding System (ABCS), a video-based instrument to assess core autism symptoms during therapist-child interaction. Video sequences of 40 young children treated in the Fruhintervention bei Autistischen Storungen center were analyzed with regard to the question of whether short-term changes during an 18 day period of early intervention could be captured, and whether these results are reflected in an independent clinical assessment (Developmental Disorders-Child-Global Assessment Scale [DD-C-GAS]). ABCS results showed statistically significant improvements on behavioral domains such as "expression of wishes" and "social cooperative behavior" (P < 0.01), less pronounced on "eye contact." Improvements on the DD-C-GAS were highly significant on all subdomains. Both scales showed high correlations within their subdomains, yet no significant correlations between the changes in both instruments' scores were found. An additional analysis between the DD-C-GAS scores at day 18 and the changes in the ABCS scores showed statistically significant associations in the expected direction between the changes in the variable "eye contact" and all DD-C-GAS subdomains. The correspondence of the two levels of assessment is low, but the specifics of this relationship deserve further study. The ABCS may prove useful in addition to standard assessment tools, especially in early intervention research settings, as it allows reliable analysis of core behavioral elements in young children with autism. Autism Res 2019, 12: 1817-1828. (c) 2019 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: The study examined the sensitivity of an autism-specific video coding system (ABCS) in assessing changes after an 18 day period of intensive early intervention. Video sequences of therapist-child-interaction of 40 young children with autism spectrum disorder (ASD) were analyzed. Children's behavior improved in expression of wishes, social cooperativity and eye contact. A therapist-based global assessment scale also showed important improvement after 18 days, yet both assessment instruments showed weak correlations between their respective changes. We showed that the ABCS may prove useful in capturing short-term changes in autism-related behaviors, especially in early intervention research. En ligne : http://dx.doi.org/10.1002/aur.2188 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1817-1828[article] Process research in early intensive intervention in autism spectrum disorder: Sensitivity to change of the autism behavior coding system [Texte imprimé et/ou numérique] / E. HERBRECHT, Auteur ; O. LAZARI, Auteur ; M. NOTTER, Auteur ; K. SCHMECK, Auteur ; R. SPIEGEL, Auteur . - 2019 . - p.1817-1828.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1817-1828
Mots-clés : Abcs autism spectrum disorder early intensive intervention process research sensitivity to change Index. décimale : PER Périodiques Résumé : The development of sensitive measures to capture changes in core autism symptoms is crucial in early intervention research. The study examines the sensitivity to change of the Autism Behavior Coding System (ABCS), a video-based instrument to assess core autism symptoms during therapist-child interaction. Video sequences of 40 young children treated in the Fruhintervention bei Autistischen Storungen center were analyzed with regard to the question of whether short-term changes during an 18 day period of early intervention could be captured, and whether these results are reflected in an independent clinical assessment (Developmental Disorders-Child-Global Assessment Scale [DD-C-GAS]). ABCS results showed statistically significant improvements on behavioral domains such as "expression of wishes" and "social cooperative behavior" (P < 0.01), less pronounced on "eye contact." Improvements on the DD-C-GAS were highly significant on all subdomains. Both scales showed high correlations within their subdomains, yet no significant correlations between the changes in both instruments' scores were found. An additional analysis between the DD-C-GAS scores at day 18 and the changes in the ABCS scores showed statistically significant associations in the expected direction between the changes in the variable "eye contact" and all DD-C-GAS subdomains. The correspondence of the two levels of assessment is low, but the specifics of this relationship deserve further study. The ABCS may prove useful in addition to standard assessment tools, especially in early intervention research settings, as it allows reliable analysis of core behavioral elements in young children with autism. Autism Res 2019, 12: 1817-1828. (c) 2019 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: The study examined the sensitivity of an autism-specific video coding system (ABCS) in assessing changes after an 18 day period of intensive early intervention. Video sequences of therapist-child-interaction of 40 young children with autism spectrum disorder (ASD) were analyzed. Children's behavior improved in expression of wishes, social cooperativity and eye contact. A therapist-based global assessment scale also showed important improvement after 18 days, yet both assessment instruments showed weak correlations between their respective changes. We showed that the ABCS may prove useful in capturing short-term changes in autism-related behaviors, especially in early intervention research. En ligne : http://dx.doi.org/10.1002/aur.2188 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Online Processing of Subject-Verb-Object Order in a Diverse Sample of Mandarin-Exposed Preschool Children with Autism Spectrum Disorder / Y. E. SU in Autism Research, 12-12 (December)
[article]
Titre : Online Processing of Subject-Verb-Object Order in a Diverse Sample of Mandarin-Exposed Preschool Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Y. E. SU, Auteur ; L. R. NAIGLES, Auteur Année de publication : 2019 Article en page(s) : p.1829-1844 Langues : Anglais (eng) Mots-clés : Mandarin Chinese grammar online sentence processing preschoolers word order Index. décimale : PER Périodiques Résumé : Grammatical comprehension remains a strength in English-exposed young children with autism spectrum disorder (ASD), yet limited research has investigated how preschool children with ASD process grammatical structures in real time, in any language. Using the eye-movement measures of Intermodal Preferential Looking, we assessed online processing of subject-verb-object (SVO) order in seventy 2- to 5-year-old children with ASD exposed to Mandarin Chinese across the spectrum, whose vocabulary production scores were dramatically delayed compared with the typical controls. With this Mandarin-exposed sample, we tested the extent to which children with ASD require (a) highly consistent input and/or (b) good discourse/pragmatics for acquiring grammatical structures. Children viewed side-by-side videos depicting reversible actions (e.g., a bird pushing a horse vs. a horse pushing a bird), and heard an audio matching only one of those actions; their eyegaze to each video was coded and analyzed. Both typically developing children and children with ASD demonstrated comprehension of SVO word order, suggesting that core grammatical structures such as basic word order may be preserved in children with ASD across languages despite radical differences in language environment, social/pragmatic abilities, and neurological organization. However, children with ASD were less efficient in online sentence processing than typical children, and the efficiency of their online sentence processing was related to their standardized language assessment scores. Of note is that across both Mandarin Chinese and English, some proportion of minimally verbal children with ASD exhibited SVO comprehension despite their profoundly impaired expressive language skills. Autism Res 2019, 12: 1829-1844. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Grammar is a strength in the language comprehension of young English learners with autism spectrum disorder (ASD). Eye-movement data from a diverse sample of Chinese preschoolers with ASD indicated similar grammatical strength of basic word order in Chinese (e.g., to understand sentences like "The bird is pushing the horse"). Moreover, children's proficiency of sentence processing was related to their language assessment scores. Across languages, such knowledge is even spared in some minimally verbal children with ASD. En ligne : http://dx.doi.org/10.1002/aur.2190 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1829-1844[article] Online Processing of Subject-Verb-Object Order in a Diverse Sample of Mandarin-Exposed Preschool Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Y. E. SU, Auteur ; L. R. NAIGLES, Auteur . - 2019 . - p.1829-1844.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1829-1844
Mots-clés : Mandarin Chinese grammar online sentence processing preschoolers word order Index. décimale : PER Périodiques Résumé : Grammatical comprehension remains a strength in English-exposed young children with autism spectrum disorder (ASD), yet limited research has investigated how preschool children with ASD process grammatical structures in real time, in any language. Using the eye-movement measures of Intermodal Preferential Looking, we assessed online processing of subject-verb-object (SVO) order in seventy 2- to 5-year-old children with ASD exposed to Mandarin Chinese across the spectrum, whose vocabulary production scores were dramatically delayed compared with the typical controls. With this Mandarin-exposed sample, we tested the extent to which children with ASD require (a) highly consistent input and/or (b) good discourse/pragmatics for acquiring grammatical structures. Children viewed side-by-side videos depicting reversible actions (e.g., a bird pushing a horse vs. a horse pushing a bird), and heard an audio matching only one of those actions; their eyegaze to each video was coded and analyzed. Both typically developing children and children with ASD demonstrated comprehension of SVO word order, suggesting that core grammatical structures such as basic word order may be preserved in children with ASD across languages despite radical differences in language environment, social/pragmatic abilities, and neurological organization. However, children with ASD were less efficient in online sentence processing than typical children, and the efficiency of their online sentence processing was related to their standardized language assessment scores. Of note is that across both Mandarin Chinese and English, some proportion of minimally verbal children with ASD exhibited SVO comprehension despite their profoundly impaired expressive language skills. Autism Res 2019, 12: 1829-1844. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Grammar is a strength in the language comprehension of young English learners with autism spectrum disorder (ASD). Eye-movement data from a diverse sample of Chinese preschoolers with ASD indicated similar grammatical strength of basic word order in Chinese (e.g., to understand sentences like "The bird is pushing the horse"). Moreover, children's proficiency of sentence processing was related to their language assessment scores. Across languages, such knowledge is even spared in some minimally verbal children with ASD. En ligne : http://dx.doi.org/10.1002/aur.2190 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Maternal immigrant status and signs of neurodevelopmental problems in early childhood: The French representative ELFE birth cohort / H. SCHMENGLER in Autism Research, 12-12 (December)
[article]
Titre : Maternal immigrant status and signs of neurodevelopmental problems in early childhood: The French representative ELFE birth cohort Type de document : Texte imprimé et/ou numérique Auteurs : H. SCHMENGLER, Auteur ; F. EL-KHOURY LESUEUR, Auteur ; A. YERMACHENKO, Auteur ; M. TAINE, Auteur ; D. COHEN, Auteur ; H. PEYRE, Auteur ; C. SAINT-GEORGES, Auteur ; X. THIERRY, Auteur ; M. MELCHIOR, Auteur Année de publication : 2019 Article en page(s) : p.1845-1859 Langues : Anglais (eng) Mots-clés : autism spectrum disorder child development developmental disabilities immigrants language Index. décimale : PER Périodiques Résumé : A growing body of evidence suggests that children of immigrants may have increased risks of neurodevelopmental disorders. However, evidence based on parent report and on very young children is lacking. We therefore investigated the association between maternal immigrant status and early signs of neurodevelopmental problems in a population-based sample of 2-year-old children using standardized parent-report instruments. We used data from the French representative Etude Longitudinale Francaise depuis l'Enfance birth cohort, initiated in 2011. The study sample included 9,900 children of nonimmigrant French, 1,403 children of second, and 1,171 children of first generation immigrant women followed-up to age 2 years. Neurodevelopment was assessed using the Modified Checklist for Autism in Toddlers (M-CHAT) and an adaptation of the MacArthur-Bates Communicative Development Inventories (MB-CDI). In fully adjusted linear regression models, maternal immigrant status was associated with M-CHAT scores, with stronger associations in children of first (beta-coefficient: 0.19; 95% CI 0.08-0.29) than second generation immigrants (0.09; 0.01-0.17). This association was especially strong among children of first generation immigrant mothers native of North Africa (vs. nonimmigrant French: 0.33; 0.16-0.49) and French-speaking Sub-Saharan Africa (0.26; 0.07-0.45). MB-CDI scores were lowest among children of first generation immigrant mothers, particularly from mostly non-francophone regions. Children of first generation immigrant mothers were most likely to have simultaneously low MB-CDI and high M-CHAT scores. Our findings suggest that maternal immigrant status is associated with early signs of neurodevelopmental difficulties, with strong variations according to maternal region of origin. Further research is necessary to test whether these associations persist and to determine the underlying mechanisms. Autism Res 2019, 12: 1845-1859. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: We asked immigrant and nonimmigrant mothers in France about early signs of neurodevelopmental problems in their 2-year-old children. Overall, we found that children of immigrants may be at higher risk of showing these early warning signs, as compared to children of nonimmigrants. This is in line with previous studies, which were based on doctors' diagnoses at later ages. However, our results differed depending on the mothers' regions of origin. We found the highest risks in children of first generation immigrants from North and French-speaking Sub-Saharan Africa, who also seemed especially at risk of neurodevelopmental problems combined with low language development. En ligne : http://dx.doi.org/10.1002/aur.2181 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1845-1859[article] Maternal immigrant status and signs of neurodevelopmental problems in early childhood: The French representative ELFE birth cohort [Texte imprimé et/ou numérique] / H. SCHMENGLER, Auteur ; F. EL-KHOURY LESUEUR, Auteur ; A. YERMACHENKO, Auteur ; M. TAINE, Auteur ; D. COHEN, Auteur ; H. PEYRE, Auteur ; C. SAINT-GEORGES, Auteur ; X. THIERRY, Auteur ; M. MELCHIOR, Auteur . - 2019 . - p.1845-1859.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1845-1859
Mots-clés : autism spectrum disorder child development developmental disabilities immigrants language Index. décimale : PER Périodiques Résumé : A growing body of evidence suggests that children of immigrants may have increased risks of neurodevelopmental disorders. However, evidence based on parent report and on very young children is lacking. We therefore investigated the association between maternal immigrant status and early signs of neurodevelopmental problems in a population-based sample of 2-year-old children using standardized parent-report instruments. We used data from the French representative Etude Longitudinale Francaise depuis l'Enfance birth cohort, initiated in 2011. The study sample included 9,900 children of nonimmigrant French, 1,403 children of second, and 1,171 children of first generation immigrant women followed-up to age 2 years. Neurodevelopment was assessed using the Modified Checklist for Autism in Toddlers (M-CHAT) and an adaptation of the MacArthur-Bates Communicative Development Inventories (MB-CDI). In fully adjusted linear regression models, maternal immigrant status was associated with M-CHAT scores, with stronger associations in children of first (beta-coefficient: 0.19; 95% CI 0.08-0.29) than second generation immigrants (0.09; 0.01-0.17). This association was especially strong among children of first generation immigrant mothers native of North Africa (vs. nonimmigrant French: 0.33; 0.16-0.49) and French-speaking Sub-Saharan Africa (0.26; 0.07-0.45). MB-CDI scores were lowest among children of first generation immigrant mothers, particularly from mostly non-francophone regions. Children of first generation immigrant mothers were most likely to have simultaneously low MB-CDI and high M-CHAT scores. Our findings suggest that maternal immigrant status is associated with early signs of neurodevelopmental difficulties, with strong variations according to maternal region of origin. Further research is necessary to test whether these associations persist and to determine the underlying mechanisms. Autism Res 2019, 12: 1845-1859. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: We asked immigrant and nonimmigrant mothers in France about early signs of neurodevelopmental problems in their 2-year-old children. Overall, we found that children of immigrants may be at higher risk of showing these early warning signs, as compared to children of nonimmigrants. This is in line with previous studies, which were based on doctors' diagnoses at later ages. However, our results differed depending on the mothers' regions of origin. We found the highest risks in children of first generation immigrants from North and French-speaking Sub-Saharan Africa, who also seemed especially at risk of neurodevelopmental problems combined with low language development. En ligne : http://dx.doi.org/10.1002/aur.2181 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Implication of hypocholesterolemia in autism spectrum disorder and its associated comorbidities: A retrospective case-control study / S. BENACHENHOU in Autism Research, 12-12 (December)
[article]
Titre : Implication of hypocholesterolemia in autism spectrum disorder and its associated comorbidities: A retrospective case-control study Type de document : Texte imprimé et/ou numérique Auteurs : S. BENACHENHOU, Auteur ; A. ETCHEVERRY, Auteur ; L. GALARNEAU, Auteur ; J. DUBE, Auteur ; A. CAKU, Auteur Année de publication : 2019 Article en page(s) : p.1860-1869 Langues : Anglais (eng) Mots-clés : Fragile X Syndrome anxiety/depression autism spectrum disorder cholesterol hypocholesterolemia intellectual disability prevalence Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) has been associated with low cholesterol levels in a limited number of studies. However, the prevalence of hypocholesterolemia as well as the degree of association with ASD remains to be elucidated. We therefore sought to investigate the lipid profiles of a group of French-Canadian ASD individuals. The medical records of 79 ASD individuals and 79 age and gender-matched healthy controls were retrospectively reviewed. The fasting lipid profiles including total cholesterol (TC), high-density lipoprotein, triglycerides, and low-density lipoprotein were extracted for individuals of both groups along with the following clinical data: anthropometric measurements, medication use and associated disorders. Lipid parameters were compared to age and gender-based normative population and categorized in centile groups. The prevalence of hypocholesterolemia was revealed to be more than threefold higher in ASD individuals as compared to the general population (23%; P = 0.005). The 25th centile was determined as a potential TC threshold that could best predict the ASD (odds ratio [OR] = 3.04; 95% confidence interval [CI]: 1.58-6.65; P < 0.001). This study identified specific ASD comorbidities associated with hypocholesterolemia: TC levels below the 10th centile were associated with a higher rate of ASD-associated intellectual disability (OR = 3.33; 95% CI: 1.26-8.00) and anxiety/depression (OR = 4.74; 95% CI: 1.40-15.73). Overall, these results support a potential association between hypocholesterolemia and ASD occurrence. Application of this study to larger populations is urging to provide more extensive data that may further elucidate the association between hypocholesterolemia and ASD. Autism Res 2019, 12: 1860-1869. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Association of autism spectrum disorder (ASD) with abnormally low levels of cholesterol (hypocholesterolemia) has been documented before. These studies were incomplete, and the conclusion remains speculative. Here, we reviewed the medical records of 79 French-Canadian ASD individuals and compared their total cholesterol (TC) levels to healthy individuals matched for age and gender. We observed four times more hypocholesterolemia in ASD than in the general population. Furthermore, low TC in ASD was associated with higher rates of ASD-associated intellectual disability and anxiety/depression. Our results support an association between hypocholesterolemia and ASD and open novel opportunities for the diagnosis and treatment of specific forms of ASD. En ligne : http://dx.doi.org/10.1002/aur.2183 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1860-1869[article] Implication of hypocholesterolemia in autism spectrum disorder and its associated comorbidities: A retrospective case-control study [Texte imprimé et/ou numérique] / S. BENACHENHOU, Auteur ; A. ETCHEVERRY, Auteur ; L. GALARNEAU, Auteur ; J. DUBE, Auteur ; A. CAKU, Auteur . - 2019 . - p.1860-1869.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1860-1869
Mots-clés : Fragile X Syndrome anxiety/depression autism spectrum disorder cholesterol hypocholesterolemia intellectual disability prevalence Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) has been associated with low cholesterol levels in a limited number of studies. However, the prevalence of hypocholesterolemia as well as the degree of association with ASD remains to be elucidated. We therefore sought to investigate the lipid profiles of a group of French-Canadian ASD individuals. The medical records of 79 ASD individuals and 79 age and gender-matched healthy controls were retrospectively reviewed. The fasting lipid profiles including total cholesterol (TC), high-density lipoprotein, triglycerides, and low-density lipoprotein were extracted for individuals of both groups along with the following clinical data: anthropometric measurements, medication use and associated disorders. Lipid parameters were compared to age and gender-based normative population and categorized in centile groups. The prevalence of hypocholesterolemia was revealed to be more than threefold higher in ASD individuals as compared to the general population (23%; P = 0.005). The 25th centile was determined as a potential TC threshold that could best predict the ASD (odds ratio [OR] = 3.04; 95% confidence interval [CI]: 1.58-6.65; P < 0.001). This study identified specific ASD comorbidities associated with hypocholesterolemia: TC levels below the 10th centile were associated with a higher rate of ASD-associated intellectual disability (OR = 3.33; 95% CI: 1.26-8.00) and anxiety/depression (OR = 4.74; 95% CI: 1.40-15.73). Overall, these results support a potential association between hypocholesterolemia and ASD occurrence. Application of this study to larger populations is urging to provide more extensive data that may further elucidate the association between hypocholesterolemia and ASD. Autism Res 2019, 12: 1860-1869. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Association of autism spectrum disorder (ASD) with abnormally low levels of cholesterol (hypocholesterolemia) has been documented before. These studies were incomplete, and the conclusion remains speculative. Here, we reviewed the medical records of 79 French-Canadian ASD individuals and compared their total cholesterol (TC) levels to healthy individuals matched for age and gender. We observed four times more hypocholesterolemia in ASD than in the general population. Furthermore, low TC in ASD was associated with higher rates of ASD-associated intellectual disability and anxiety/depression. Our results support an association between hypocholesterolemia and ASD and open novel opportunities for the diagnosis and treatment of specific forms of ASD. En ligne : http://dx.doi.org/10.1002/aur.2183 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 Incidence time trends and socioeconomic factors in the observed incidence of autism spectrum disorder in israel: A nationwide nested case-control study / A. SEGEV in Autism Research, 12-12 (December)
[article]
Titre : Incidence time trends and socioeconomic factors in the observed incidence of autism spectrum disorder in israel: A nationwide nested case-control study Type de document : Texte imprimé et/ou numérique Auteurs : A. SEGEV, Auteur ; Marc G. WEISSKOPF, Auteur ; H. LEVINE, Auteur ; O. PINTO, Auteur ; R. RAZ, Auteur Année de publication : 2019 Article en page(s) : p.1870-1879 Langues : Anglais (eng) Mots-clés : Israel autism spectrum disorder incidence socioeconomic factors Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) trends have been gaining a great deal of focus in recent decades, as many studies worldwide show a continued rise in incidence rates. Many researchers have begun analyzing socioeconomic data in relation to ASD in an effort to understand the source of these changing rates and the role of awareness and access to resources. In this study, we aim to contribute to this body of knowledge by examining incidence time trends of ASD in Israel according to socioeconomic factors. While similar studies have been conducted in Israel, this study is the first of its kind to include the total population. Individual-level data from the Israeli National Insurance Institute were used to determine cumulative incidence of ASD, first for the total population, and then stratified by population group and income categories. Multivariable logistic regression models were fit to analyze associations between income category and both risk of ASD and risk of ASD diagnosis in later age. A total of 431,348 children were examined in this study, with 13,841 cases of ASD. The cumulative incidence of all children aged 8 in 2015 was 0.64%, marking an increase compared to previous literature from Israel. Within our study period, ASD incidence followed this increase until the 2009 birth cohort, where it began to stabilize. Our initial findings from regression models showed strong positive associations between household income and ASD incidence, as expected. After factoring in population group, however, the elevated ASD incidence rates in the highest income bracket decreased. Autism Res 2019, 12: 1870-1879. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study contributes comprehensive and current data on ASD trends overtime in Israel and introduces crucial insights regarding the impact of socioeconomic factors on ASD diagnoses. We found a rise in ASD that began leveling off in 2009. We identified more ASD diagnoses occurring in families with higher incomes and in the General Population, pointing to the important role of sociodemographic factors on ASD diagnoses. En ligne : http://dx.doi.org/10.1002/aur.2185 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1870-1879[article] Incidence time trends and socioeconomic factors in the observed incidence of autism spectrum disorder in israel: A nationwide nested case-control study [Texte imprimé et/ou numérique] / A. SEGEV, Auteur ; Marc G. WEISSKOPF, Auteur ; H. LEVINE, Auteur ; O. PINTO, Auteur ; R. RAZ, Auteur . - 2019 . - p.1870-1879.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1870-1879
Mots-clés : Israel autism spectrum disorder incidence socioeconomic factors Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) trends have been gaining a great deal of focus in recent decades, as many studies worldwide show a continued rise in incidence rates. Many researchers have begun analyzing socioeconomic data in relation to ASD in an effort to understand the source of these changing rates and the role of awareness and access to resources. In this study, we aim to contribute to this body of knowledge by examining incidence time trends of ASD in Israel according to socioeconomic factors. While similar studies have been conducted in Israel, this study is the first of its kind to include the total population. Individual-level data from the Israeli National Insurance Institute were used to determine cumulative incidence of ASD, first for the total population, and then stratified by population group and income categories. Multivariable logistic regression models were fit to analyze associations between income category and both risk of ASD and risk of ASD diagnosis in later age. A total of 431,348 children were examined in this study, with 13,841 cases of ASD. The cumulative incidence of all children aged 8 in 2015 was 0.64%, marking an increase compared to previous literature from Israel. Within our study period, ASD incidence followed this increase until the 2009 birth cohort, where it began to stabilize. Our initial findings from regression models showed strong positive associations between household income and ASD incidence, as expected. After factoring in population group, however, the elevated ASD incidence rates in the highest income bracket decreased. Autism Res 2019, 12: 1870-1879. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study contributes comprehensive and current data on ASD trends overtime in Israel and introduces crucial insights regarding the impact of socioeconomic factors on ASD diagnoses. We found a rise in ASD that began leveling off in 2009. We identified more ASD diagnoses occurring in families with higher incomes and in the General Population, pointing to the important role of sociodemographic factors on ASD diagnoses. En ligne : http://dx.doi.org/10.1002/aur.2185 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 A comparison of the ASD experience of low-SES hispanic and non-hispanic white parents / A. FERGUSON in Autism Research, 12-12 (December)
[article]
Titre : A comparison of the ASD experience of low-SES hispanic and non-hispanic white parents Type de document : Texte imprimé et/ou numérique Auteurs : A. FERGUSON, Auteur ; D. C. VIGIL, Auteur Année de publication : 2019 Article en page(s) : p.1880-1890 Langues : Anglais (eng) Mots-clés : Hispanic Ses autism spectrum disorder Index. décimale : PER Périodiques Résumé : This study compared the experiences of Hispanic families, who were primarily of Mexican heritage, and non-Hispanic White families from the United States both from low socioeconomic status (SES) backgrounds having a child with a diagnosis of Autism Spectrum Disorder (ASD). The Centers for Disease Control and Prevention (CDC) reports that Hispanic children are diagnosed with ASD 2 years later than non-Hispanic White children [Baio et al., MMWR Surveillance Summaries 2018:67(SS-6): 1-23]. However, there has been limited investigation in exploring how SES might impact both diagnosis and experience. A survey of basic demographic information and a qualitative survey were used for this study. Basic demographic information obtained included SES, parent educational level, age of diagnosis of the children, religious affiliation, and marital status. Hour-long interviews were conducted to gather information about the personal experiences of these families relating to diagnoses and treatment. Comparative results of basic demographic information showed no difference in age of diagnosis between the two groups when SES was controlled. Although SES was controlled, the non-Hispanic White families had a higher education level and were slightly wealthier. Qualitatively, similarities included family support, doctor response to parent concerns, and acceptance of diagnosis by family members and friends. Differences included religious views, acceptance of diagnosis, knowledge of developmental milestones, and finding resources. Most significantly, the findings indicate no difference in the age of diagnosis of ASD between the Hispanic and non-Hispanic White children, which could be attributed to increased awareness and having access to a proactive parent organization. Autism Res 2019, 12: 1880-1890. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study showed that Hispanic and Non-Hispanic White children from poor backgrounds got a diagnosis of Autism Spectrum Disorder (ASD) at the same age. Results show differences in religious views, acceptance of diagnosis, knowledge of milestones, and finding resources. This might be because people are more aware of ASD today and Hispanic families were involved with an active parent organization. En ligne : http://dx.doi.org/10.1002/aur.2223 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1880-1890[article] A comparison of the ASD experience of low-SES hispanic and non-hispanic white parents [Texte imprimé et/ou numérique] / A. FERGUSON, Auteur ; D. C. VIGIL, Auteur . - 2019 . - p.1880-1890.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1880-1890
Mots-clés : Hispanic Ses autism spectrum disorder Index. décimale : PER Périodiques Résumé : This study compared the experiences of Hispanic families, who were primarily of Mexican heritage, and non-Hispanic White families from the United States both from low socioeconomic status (SES) backgrounds having a child with a diagnosis of Autism Spectrum Disorder (ASD). The Centers for Disease Control and Prevention (CDC) reports that Hispanic children are diagnosed with ASD 2 years later than non-Hispanic White children [Baio et al., MMWR Surveillance Summaries 2018:67(SS-6): 1-23]. However, there has been limited investigation in exploring how SES might impact both diagnosis and experience. A survey of basic demographic information and a qualitative survey were used for this study. Basic demographic information obtained included SES, parent educational level, age of diagnosis of the children, religious affiliation, and marital status. Hour-long interviews were conducted to gather information about the personal experiences of these families relating to diagnoses and treatment. Comparative results of basic demographic information showed no difference in age of diagnosis between the two groups when SES was controlled. Although SES was controlled, the non-Hispanic White families had a higher education level and were slightly wealthier. Qualitatively, similarities included family support, doctor response to parent concerns, and acceptance of diagnosis by family members and friends. Differences included religious views, acceptance of diagnosis, knowledge of developmental milestones, and finding resources. Most significantly, the findings indicate no difference in the age of diagnosis of ASD between the Hispanic and non-Hispanic White children, which could be attributed to increased awareness and having access to a proactive parent organization. Autism Res 2019, 12: 1880-1890. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study showed that Hispanic and Non-Hispanic White children from poor backgrounds got a diagnosis of Autism Spectrum Disorder (ASD) at the same age. Results show differences in religious views, acceptance of diagnosis, knowledge of milestones, and finding resources. This might be because people are more aware of ASD today and Hispanic families were involved with an active parent organization. En ligne : http://dx.doi.org/10.1002/aur.2223 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 INTERNATIONAL SOCIETY FOR AUTISM RESEARCH NEWS President's Message - December 2019 Updates on Seattle 2020, New Web Design and App, Board Elections, Journal News and a Report from the Strategic Planning Meeting / Peter C. MUNDY in Autism Research, 12-12 (December)
[article]
Titre : INTERNATIONAL SOCIETY FOR AUTISM RESEARCH NEWS President's Message - December 2019 Updates on Seattle 2020, New Web Design and App, Board Elections, Journal News and a Report from the Strategic Planning Meeting Type de document : Texte imprimé et/ou numérique Auteurs : Peter C. MUNDY, Auteur Année de publication : 2019 Article en page(s) : p.1891 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2248 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413
in Autism Research > 12-12 (December) . - p.1891[article] INTERNATIONAL SOCIETY FOR AUTISM RESEARCH NEWS President's Message - December 2019 Updates on Seattle 2020, New Web Design and App, Board Elections, Journal News and a Report from the Strategic Planning Meeting [Texte imprimé et/ou numérique] / Peter C. MUNDY, Auteur . - 2019 . - p.1891.
Langues : Anglais (eng)
in Autism Research > 12-12 (December) . - p.1891
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2248 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413