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A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism / Thomas W. FRAZIER in Journal of Autism and Developmental Disorders, 42-11 (November 2012)
[article]
Titre : A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Thomas W. FRAZIER, Auteur ; Matcheri S. KESHAVAN, Auteur ; Nancy J. MINSHEW, Auteur ; Antonio Y. HARDAN, Auteur Article en page(s) : p.2312-2322 Langues : Anglais (eng) Mots-clés : Magnetic resonance imaging Autism Corpus callosum Rostral body Index. décimale : PER Périodiques Résumé : A growing body of literature has identified size reductions of the corpus callosum (CC) in autism. However, to our knowledge, no published studies have reported on the growth of CC volumes in youth with autism. Volumes of the total CC and its sub-divisions were obtained from 23 male children with autism and 23 age- and gender-matched controls at baseline and 2-year follow-up. Persistent reductions in total CC volume were observed in participants with autism relative to controls. Only the rostral body subdivision showed a normalization of size over time. Persistent reductions are consistent with the diagnostic stability and life-long impairment observed in many individuals with autism. Multi-modal imaging studies are needed to identify specific fiber tracks contributing to CC reductions. En ligne : http://dx.doi.org/10.1007/s10803-012-1478-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=182
in Journal of Autism and Developmental Disorders > 42-11 (November 2012) . - p.2312-2322[article] A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism [Texte imprimé et/ou numérique] / Thomas W. FRAZIER, Auteur ; Matcheri S. KESHAVAN, Auteur ; Nancy J. MINSHEW, Auteur ; Antonio Y. HARDAN, Auteur . - p.2312-2322.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-11 (November 2012) . - p.2312-2322
Mots-clés : Magnetic resonance imaging Autism Corpus callosum Rostral body Index. décimale : PER Périodiques Résumé : A growing body of literature has identified size reductions of the corpus callosum (CC) in autism. However, to our knowledge, no published studies have reported on the growth of CC volumes in youth with autism. Volumes of the total CC and its sub-divisions were obtained from 23 male children with autism and 23 age- and gender-matched controls at baseline and 2-year follow-up. Persistent reductions in total CC volume were observed in participants with autism relative to controls. Only the rostral body subdivision showed a normalization of size over time. Persistent reductions are consistent with the diagnostic stability and life-long impairment observed in many individuals with autism. Multi-modal imaging studies are needed to identify specific fiber tracks contributing to CC reductions. En ligne : http://dx.doi.org/10.1007/s10803-012-1478-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=182