637 recherche sur le mot-clé 'twin-studies'

Chaotic homes and school achievement: a twin study / Ken B. HANSCOMBE in Journal of Child Psychology and Psychiatry, 52-11 (November 2011)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 52-11 (November 2011) . - p.1212-1220 Titre : Chaotic homes and school achievement: a twin study Type de document : texte imprimé Auteurs : Ken B. HANSCOMBE, Auteur ; Claire Margaret Alison HAWORTH, Auteur ; Oliver S.P. DAVIS, Auteur ; Sara R. JAFFEE, Auteur ; Robert PLOMIN, Auteur Année de publication : 2011 Article en page(s) : p.1212-1220 Langues : Anglais (eng) Mots-clés : Gene–environment correlation  household chaos  environmental confusion  home environment  school achievement  twin studies  behavioural genetics Index. décimale : PER Périodiques Résumé : Background:  Chaotic homes predict poor school performance. Given that it is known that genes affect both children’s experience of household chaos and their school achievement, to what extent is the relationship between high levels of noise and environmental confusion in the home, and children’s school performance, mediated by heritable child effects? This is the first study to explore the genetic and environmental pathways between household chaos and academic performance. Method:  Children’s perceptions of family chaos at ages 9 and 12 and their school performance at age 12 were assessed in more than 2,300 twin pairs. The use of child-specific measures in a multivariate genetic analysis made it possible to investigate the genetic and environmental origins of the covariation between children’s experience of chaos in the home and their school achievement. Results:  Children’s experience of family chaos and their school achievement were significantly correlated in the expected negative direction (r = −.26). As expected, shared environmental factors explained a large proportion (63%) of the association. However, genetic factors accounted for a significant proportion (37%) of the association between children’s experience of household chaos and their school performance. Conclusions:  The association between chaotic homes and poor performance in school, previously assumed to be entirely environmental in origin, is in fact partly genetic. How children’s home environment affects their academic achievement is not simply in the direction environment → child → outcome. Instead, genetic factors that influence children’s experience of the disordered home environment also affect how well they do at school. The relationship between the child, their environment and their performance at school is complex: both genetic and environmental factors play a role. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02421.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=145 [article] Chaotic homes and school achievement: a twin study [texte imprimé] / Ken B. HANSCOMBE, Auteur ; Claire Margaret Alison HAWORTH, Auteur ; Oliver S.P. DAVIS, Auteur ; Sara R. JAFFEE, Auteur ; Robert PLOMIN, Auteur . - 2011 . - p.1212-1220. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 52-11 (November 2011) . - p.1212-1220 Mots-clés : Gene–environment correlation  household chaos  environmental confusion  home environment  school achievement  twin studies  behavioural genetics Index. décimale : PER Périodiques Résumé : Background:  Chaotic homes predict poor school performance. Given that it is known that genes affect both children’s experience of household chaos and their school achievement, to what extent is the relationship between high levels of noise and environmental confusion in the home, and children’s school performance, mediated by heritable child effects? This is the first study to explore the genetic and environmental pathways between household chaos and academic performance. Method:  Children’s perceptions of family chaos at ages 9 and 12 and their school performance at age 12 were assessed in more than 2,300 twin pairs. The use of child-specific measures in a multivariate genetic analysis made it possible to investigate the genetic and environmental origins of the covariation between children’s experience of chaos in the home and their school achievement. Results:  Children’s experience of family chaos and their school achievement were significantly correlated in the expected negative direction (r = −.26). As expected, shared environmental factors explained a large proportion (63%) of the association. However, genetic factors accounted for a significant proportion (37%) of the association between children’s experience of household chaos and their school performance. Conclusions:  The association between chaotic homes and poor performance in school, previously assumed to be entirely environmental in origin, is in fact partly genetic. How children’s home environment affects their academic achievement is not simply in the direction environment → child → outcome. Instead, genetic factors that influence children’s experience of the disordered home environment also affect how well they do at school. The relationship between the child, their environment and their performance at school is complex: both genetic and environmental factors play a role. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02421.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=145

Commentary: The strength of multivariate twin studies: testing for shared and distinctive aetiology among different sets of behavioural traits – reflections on Lewis et al. (2014) / Dorret I. BOOMSMA in Journal of Child Psychology and Psychiatry, 55-8 (August 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-8 (August 2014) . - p.876-877 Titre : Commentary: The strength of multivariate twin studies: testing for shared and distinctive aetiology among different sets of behavioural traits – reflections on Lewis et al. (2014) Type de document : texte imprimé Auteurs : Dorret I. BOOMSMA, Auteur Article en page(s) : p.876-877 Langues : Anglais (eng) Mots-clés : Adolescent behavioural problems  twin studies  multivariate traits  etiology  genetic pleiotropy Index. décimale : PER Périodiques Résumé : This contribution discusses the article by Lewis et al. on the relationship between variation in normal personality and adolescent behavioural problems and puts the study into the perspective of the value of twin studies of multivariate behavioural traits, which enable the analyses of genetic pleiotropy and causality. En ligne : http://dx.doi.org/10.1111/jcpp.12292 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=237 [article] Commentary: The strength of multivariate twin studies: testing for shared and distinctive aetiology among different sets of behavioural traits – reflections on Lewis et al. (2014) [texte imprimé] / Dorret I. BOOMSMA, Auteur . - p.876-877. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-8 (August 2014) . - p.876-877 Mots-clés : Adolescent behavioural problems  twin studies  multivariate traits  etiology  genetic pleiotropy Index. décimale : PER Périodiques Résumé : This contribution discusses the article by Lewis et al. on the relationship between variation in normal personality and adolescent behavioural problems and puts the study into the perspective of the value of twin studies of multivariate behavioural traits, which enable the analyses of genetic pleiotropy and causality. En ligne : http://dx.doi.org/10.1111/jcpp.12292 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=237

Early environmental risk factors for neurodevelopmental disorders – a systematic review of twin and sibling studies / Torkel CARLSSON in Development and Psychopathology, 33-4 (October 2021)  

Public ISBD [article]  inDevelopment and Psychopathology > 33-4 (October 2021) . - p.1448-1495 Titre : Early environmental risk factors for neurodevelopmental disorders – a systematic review of twin and sibling studies Type de document : texte imprimé Auteurs : Torkel CARLSSON, Auteur ; Felix MOLANDER, Auteur ; Mark J. TAYLOR, Auteur ; Ulf JONSSON, Auteur ; Sven BÖLTE, Auteur Article en page(s) : p.1448-1495 Langues : Anglais (eng) Mots-clés : confounding factors  environmental exposure  neurodevelopmental disorders  systematic review  twin and sibling studies Index. décimale : PER Périodiques Résumé : While neurodevelopmental disorders (NDDs) are highly heritable, several environmental risk factors have also been suggested. However, the role of familial confounding is unclear. To shed more light on this, we reviewed the evidence from twin and sibling studies. A systematic review was performed on case control and cohort studies including a twin or sibling within-pair comparison of neurodevelopmental outcomes, with environmental exposures until the sixth birthday. From 7,315 screened abstracts, 140 eligible articles were identified. After adjustment for familial confounding advanced paternal age, low birth weight, birth defects, and perinatal hypoxia and respiratory stress were associated with autism spectrum disorder (ASD), and low birth weight, gestational age and family income were associated with attention-deficit/hyperactivity disorder (ADHD), categorically and dimensionally. Several previously suspected factors, including pregnancy-related factors, were deemed due to familial confounding. Most studies were conducted in North America and Scandinavia, pointing to a global research bias. Moreover, most studies focused on ASD and ADHD. This genetically informed review showed evidence for a range of environmental factors of potential casual significance in NDDs, but also points to a critical need of more genetically informed studies of good quality in the quest of the environmental causes of NDDs. En ligne : http://dx.doi.org/10.1017/S0954579420000620 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 [article] Early environmental risk factors for neurodevelopmental disorders – a systematic review of twin and sibling studies [texte imprimé] / Torkel CARLSSON, Auteur ; Felix MOLANDER, Auteur ; Mark J. TAYLOR, Auteur ; Ulf JONSSON, Auteur ; Sven BÖLTE, Auteur . - p.1448-1495. Langues : Anglais (eng) in Development and Psychopathology > 33-4 (October 2021) . - p.1448-1495 Mots-clés : confounding factors  environmental exposure  neurodevelopmental disorders  systematic review  twin and sibling studies Index. décimale : PER Périodiques Résumé : While neurodevelopmental disorders (NDDs) are highly heritable, several environmental risk factors have also been suggested. However, the role of familial confounding is unclear. To shed more light on this, we reviewed the evidence from twin and sibling studies. A systematic review was performed on case control and cohort studies including a twin or sibling within-pair comparison of neurodevelopmental outcomes, with environmental exposures until the sixth birthday. From 7,315 screened abstracts, 140 eligible articles were identified. After adjustment for familial confounding advanced paternal age, low birth weight, birth defects, and perinatal hypoxia and respiratory stress were associated with autism spectrum disorder (ASD), and low birth weight, gestational age and family income were associated with attention-deficit/hyperactivity disorder (ADHD), categorically and dimensionally. Several previously suspected factors, including pregnancy-related factors, were deemed due to familial confounding. Most studies were conducted in North America and Scandinavia, pointing to a global research bias. Moreover, most studies focused on ASD and ADHD. This genetically informed review showed evidence for a range of environmental factors of potential casual significance in NDDs, but also points to a critical need of more genetically informed studies of good quality in the quest of the environmental causes of NDDs. En ligne : http://dx.doi.org/10.1017/S0954579420000620 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457

Early warm-rewarding parenting moderates the genetic contributions to callous-unemotional traits in childhood / Jeffrey HENRY in Journal of Child Psychology and Psychiatry, 59-12 (December 2018)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 59-12 (December 2018) . - p.1282-1288 Titre : Early warm-rewarding parenting moderates the genetic contributions to callous-unemotional traits in childhood Type de document : texte imprimé Auteurs : Jeffrey HENRY, Auteur ; Ginette DIONNE, Auteur ; Essi VIDING, Auteur ; Frank VITARO, Auteur ; Mara BRENDGEN, Auteur ; Richard E. TREMBLAY, Auteur ; Michel BOIVIN, Auteur Article en page(s) : p.1282-1288 Langues : Anglais (eng) Mots-clés : Callous-unemotional traits  gene-environment interaction  twin studies  warm/rewarding parenting Index. décimale : PER Périodiques Résumé : BACKGROUND: Previous gene-environment interaction studies of CU traits have relied on the candidate gene approach, which does not account for the entire genetic load of complex phenotypes. Moreover, these studies have not examined the role of positive environmental factors such as warm/rewarding parenting. The aim of the present study was to determine whether early warm/rewarding parenting moderates the genetic contributions (i.e., heritability) to callous-unemotional (CU) traits at school age. METHODS: Data were collected in a population sample of 662 twin pairs (Quebec Newborn Twin Study - QNTS). Mothers reported on their warm/rewarding parenting. Teachers assessed children's CU traits. These reports were subjected to twin modeling. RESULTS: Callous-unemotional traits were highly heritable, with the remaining variance accounted for by nonshared environmental factors. Warm/rewarding parenting significantly moderated the role of genes in CU traits; heritability was lower when children received high warm/rewarding parenting than when they were exposed to low warm/rewarding parenting. CONCLUSIONS: High warm/rewarding parenting may partly impede the genetic expression of CU traits. Developmental models of CU traits need to account for such gene-environment processes. En ligne : http://dx.doi.org/10.1111/jcpp.12918 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371 [article] Early warm-rewarding parenting moderates the genetic contributions to callous-unemotional traits in childhood [texte imprimé] / Jeffrey HENRY, Auteur ; Ginette DIONNE, Auteur ; Essi VIDING, Auteur ; Frank VITARO, Auteur ; Mara BRENDGEN, Auteur ; Richard E. TREMBLAY, Auteur ; Michel BOIVIN, Auteur . - p.1282-1288. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 59-12 (December 2018) . - p.1282-1288 Mots-clés : Callous-unemotional traits  gene-environment interaction  twin studies  warm/rewarding parenting Index. décimale : PER Périodiques Résumé : BACKGROUND: Previous gene-environment interaction studies of CU traits have relied on the candidate gene approach, which does not account for the entire genetic load of complex phenotypes. Moreover, these studies have not examined the role of positive environmental factors such as warm/rewarding parenting. The aim of the present study was to determine whether early warm/rewarding parenting moderates the genetic contributions (i.e., heritability) to callous-unemotional (CU) traits at school age. METHODS: Data were collected in a population sample of 662 twin pairs (Quebec Newborn Twin Study - QNTS). Mothers reported on their warm/rewarding parenting. Teachers assessed children's CU traits. These reports were subjected to twin modeling. RESULTS: Callous-unemotional traits were highly heritable, with the remaining variance accounted for by nonshared environmental factors. Warm/rewarding parenting significantly moderated the role of genes in CU traits; heritability was lower when children received high warm/rewarding parenting than when they were exposed to low warm/rewarding parenting. CONCLUSIONS: High warm/rewarding parenting may partly impede the genetic expression of CU traits. Developmental models of CU traits need to account for such gene-environment processes. En ligne : http://dx.doi.org/10.1111/jcpp.12918 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371

Effect of co-twin gender on neurodevelopmental symptoms: a twin register study / Jonna Maria ERIKSSON in Molecular Autism, 7 (2016)  

Public ISBD [article]  inMolecular Autism > 7 (2016) . - 8p. Titre : Effect of co-twin gender on neurodevelopmental symptoms: a twin register study Type de document : texte imprimé Auteurs : Jonna Maria ERIKSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Paul LICHTENSTEIN, Auteur ; Susanne BEJEROT, Auteur ; Elias ERIKSSON, Auteur Article en page(s) : 8p. Langues : Anglais (eng) Mots-clés : Attention Deficit Disorder with Hyperactivity/genetics/physiopathology  Autism Spectrum Disorder/genetics/physiopathology  Child  Comorbidity  Diseases in Twins  Female  Follow-Up Studies  Gender Identity  Humans  Interview, Psychological  Male  Neurodevelopmental Disorders/genetics/physiopathology  Parents  Pregnancy  Prenatal Exposure Delayed Effects  Sex Characteristics  Stereotyped Behavior  Sweden/epidemiology  Testosterone/physiology  Tic Disorders/genetics/physiopathology  Twins, Dizygotic/psychology  Asperger syndrome  Attention-deficit hyperactivity disorders  Autistic disorder  Symptom assessment  Twin study Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders thought to have both genetic and environmental causes. It has been hypothesized that exposure to elevated levels of prenatal testosterone is associated with elevated traits of ASD and ADHD. Assuming that testosterone levels from a dizygotic male twin fetus may lead to enhanced testosterone exposure of its co-twins, we aimed to test the prenatal testosterone hypothesis by comparing same-sex with opposite-sex dizygotic twins with respect to neurodevelopmental symptoms. METHODS: Neuropsychiatric traits were assessed in a population-based twin cohort from the Child and Adolescent Twin Study in Sweden (CATSS). Parental interviews were conducted for 16,312 dizygotic twins, 9 and 12 years old, with the Autism-Tics, ADHD, and other Comorbidities inventory (A-TAC). RESULTS: Girls with a female co-twin had an increased risk of reaching the cut-off score for ADHD compared with girls with a male co-twin. Both boys and girls with a female co-twin displayed a larger number of traits related to attention deficit and repetitive and stereotyped behaviors than those with a male twin. In girls, this also extended to social interaction and the combined measures for ASD and ADHD, however, with small effect sizes. CONCLUSIONS: Our results are reverse to what would have been expected from the prenatal testosterone hypothesis but consistent with a previous study of ASD and ADHD traits in dizygotic twins. The seemingly protective effect for girls of having a twin brother may be an effect of parent report bias, but may also be an unexpected effect of sharing the intrauterine environment with a male co-twin. En ligne : http://dx.doi.org/10.1186/s13229-016-0074-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328 [article] Effect of co-twin gender on neurodevelopmental symptoms: a twin register study [texte imprimé] / Jonna Maria ERIKSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Paul LICHTENSTEIN, Auteur ; Susanne BEJEROT, Auteur ; Elias ERIKSSON, Auteur . - 8p. Langues : Anglais (eng) in Molecular Autism > 7 (2016) . - 8p. Mots-clés : Attention Deficit Disorder with Hyperactivity/genetics/physiopathology  Autism Spectrum Disorder/genetics/physiopathology  Child  Comorbidity  Diseases in Twins  Female  Follow-Up Studies  Gender Identity  Humans  Interview, Psychological  Male  Neurodevelopmental Disorders/genetics/physiopathology  Parents  Pregnancy  Prenatal Exposure Delayed Effects  Sex Characteristics  Stereotyped Behavior  Sweden/epidemiology  Testosterone/physiology  Tic Disorders/genetics/physiopathology  Twins, Dizygotic/psychology  Asperger syndrome  Attention-deficit hyperactivity disorders  Autistic disorder  Symptom assessment  Twin study Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders thought to have both genetic and environmental causes. It has been hypothesized that exposure to elevated levels of prenatal testosterone is associated with elevated traits of ASD and ADHD. Assuming that testosterone levels from a dizygotic male twin fetus may lead to enhanced testosterone exposure of its co-twins, we aimed to test the prenatal testosterone hypothesis by comparing same-sex with opposite-sex dizygotic twins with respect to neurodevelopmental symptoms. METHODS: Neuropsychiatric traits were assessed in a population-based twin cohort from the Child and Adolescent Twin Study in Sweden (CATSS). Parental interviews were conducted for 16,312 dizygotic twins, 9 and 12 years old, with the Autism-Tics, ADHD, and other Comorbidities inventory (A-TAC). RESULTS: Girls with a female co-twin had an increased risk of reaching the cut-off score for ADHD compared with girls with a male co-twin. Both boys and girls with a female co-twin displayed a larger number of traits related to attention deficit and repetitive and stereotyped behaviors than those with a male twin. In girls, this also extended to social interaction and the combined measures for ASD and ADHD, however, with small effect sizes. CONCLUSIONS: Our results are reverse to what would have been expected from the prenatal testosterone hypothesis but consistent with a previous study of ASD and ADHD traits in dizygotic twins. The seemingly protective effect for girls of having a twin brother may be an effect of parent report bias, but may also be an unexpected effect of sharing the intrauterine environment with a male co-twin. En ligne : http://dx.doi.org/10.1186/s13229-016-0074-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328

Etiological influences on the stability of autistic traits from childhood to early adulthood: evidence from a twin study / Margot J. TAYLOR in Molecular Autism, 8 (2017)  

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Genetic and environmental influences on extreme personality dispositions in adolescent female twins / Michele L. PERGADIA in Journal of Child Psychology and Psychiatry, 47-9 (September 2006)  

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Genetic Causes of Autism Spectrum Disorders / Guillaume HUGUET  

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Heritability of autism spectrum disorders: a meta-analysis of twin studies / Beata TICK in Journal of Child Psychology and Psychiatry, 57-5 (May 2016)  

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Investigation of VDR gene polymorphisms in twins with autism spectrum disorder / Ender COSKUNPINAR in Research in Autism Spectrum Disorders, 82 (April 2021)  

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