Documents disponibles écrits par cet auteur

Associations between developmental trajectories of peer victimization, hair cortisol, and depressive symptoms: a longitudinal study / Isabelle OUELLET-MORIN in Journal of Child Psychology and Psychiatry, 62-1 (January 2021) 

Public ISBD [article]  in Journal of Child Psychology and Psychiatry > 62-1 (January 2021) . - p.19-27 Titre : Associations between developmental trajectories of peer victimization, hair cortisol, and depressive symptoms: a longitudinal study Type de document : texte imprimé Auteurs : Isabelle OUELLET-MORIN, Auteur ; Christina CANTAVE, Auteur ; Stéphane PAQUIN, Auteur ; Marie-Claude GEOFFROY, Auteur ; Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; Richard TREMBLAY, Auteur ; Michel BOIVIN, Auteur ; Sonia LUPIEN, Auteur ; Sylvana COTE, Auteur Article en page(s) : p.19-27 Langues : Anglais (eng) Mots-clés : HPA axis  Peer victimization  depression  hair cortisol  nonlinear models Index. décimale : PER Périodiques Résumé : BACKGROUND: Peer victimization has been associated with long-lasting risks for mental health. Prior research suggests that stress-related systems underlying adaptation to changing environments may be at play. To date, inconsistent findings have been reported for the hypothalamic-pituitary-adrenal (HPA) axis, and its end product cortisol. This study tested whether peer victimization was associated with hair cortisol concentrations (HCC), and whether this association varied according to sex, timing, and changes in exposure. We also examined whether peer victimization differentially predicted depressive symptoms according to HCC. METHODS: The sample comprised 556 adolescents (42.0%; 231 males) who provided hair for cortisol measurement at 17 years of age. Peer victimization was reported at seven occasions between the ages of 6 and 15 years. RESULTS: Peer victimization was nonlinearly associated with HCC for boys only, whereas changes in peer victimization were related to HCC for boys and girls. Peer victimization predicted more depressive symptoms for all participants, except those with lower HCC. CONCLUSIONS: Our findings provide further support for persistent dysregulation of the HPA axis following exposure to chronic adversity, of which the expression may change according to sex and the severity of victimization. En ligne : http://dx.doi.org/10.1111/jcpp.13228 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4350 [article] Associations between developmental trajectories of peer victimization, hair cortisol, and depressive symptoms: a longitudinal study [texte imprimé] / Isabelle OUELLET-MORIN, Auteur ; Christina CANTAVE, Auteur ; Stéphane PAQUIN, Auteur ; Marie-Claude GEOFFROY, Auteur ; Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; Richard TREMBLAY, Auteur ; Michel BOIVIN, Auteur ; Sonia LUPIEN, Auteur ; Sylvana COTE, Auteur . - p.19-27. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-1 (January 2021) . - p.19-27 Mots-clés : HPA axis  Peer victimization  depression  hair cortisol  nonlinear models Index. décimale : PER Périodiques Résumé : BACKGROUND: Peer victimization has been associated with long-lasting risks for mental health. Prior research suggests that stress-related systems underlying adaptation to changing environments may be at play. To date, inconsistent findings have been reported for the hypothalamic-pituitary-adrenal (HPA) axis, and its end product cortisol. This study tested whether peer victimization was associated with hair cortisol concentrations (HCC), and whether this association varied according to sex, timing, and changes in exposure. We also examined whether peer victimization differentially predicted depressive symptoms according to HCC. METHODS: The sample comprised 556 adolescents (42.0%; 231 males) who provided hair for cortisol measurement at 17 years of age. Peer victimization was reported at seven occasions between the ages of 6 and 15 years. RESULTS: Peer victimization was nonlinearly associated with HCC for boys only, whereas changes in peer victimization were related to HCC for boys and girls. Peer victimization predicted more depressive symptoms for all participants, except those with lower HCC. CONCLUSIONS: Our findings provide further support for persistent dysregulation of the HPA axis following exposure to chronic adversity, of which the expression may change according to sex and the severity of victimization. En ligne : http://dx.doi.org/10.1111/jcpp.13228 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4350

Can friends protect genetically vulnerable children from depression? / Mara BRENDGEN in Development and Psychopathology, 25-2 (May 2013) 

Public ISBD [article]  in Development and Psychopathology > 25-2 (May 2013) . - p.277-289 Titre : Can friends protect genetically vulnerable children from depression? Type de document : texte imprimé Auteurs : Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; William M. BUKOWSKI, Auteur ; Ginette DIONNE, Auteur ; Richard E. TREMBLAY, Auteur ; Michel BOIVIN, Auteur Article en page(s) : p.277-289 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The study examined whether reciprocal friendship quantity or quality can mitigate genetic vulnerability for depression symptoms in children. The sample comprised 168 monozygotic twin pairs and 126 same-sex dizygotic twin pairs assessed in Grade 4 (mean age = 10.04 years). Friendship participation was measured via reciprocal nominations of close friendships within the classroom. Friendship quality was measured through self-reports. Depression symptoms were measured through teacher and peer reports. Genetic vulnerability for depression symptoms was unrelated to friendship participation or the number of reciprocal friends, but it was negatively related to positive friendship quality. In line with gene–environment interaction, genetic risk effects on depression symptoms were mitigated in girls who had at least one close reciprocal friend. In boys, only moderate main effects of genetic vulnerability and friendship participation were found but no interaction between them. However, among boys with at least one reciprocal friend, a greater number of friends was related to fewer depression symptoms whereas no cumulative effect of friendship was found for girls. Finally, positive friendship quality was related to fewer depression symptoms in girls and boys even when controlling for genetic risk. The findings emphasize the importance of teaching social interactional skills that promote high-quality friendship relations to help prevent the development of depression symptoms in children. En ligne : http://dx.doi.org/10.1017/S0954579412001058 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1995 [article] Can friends protect genetically vulnerable children from depression? [texte imprimé] / Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; William M. BUKOWSKI, Auteur ; Ginette DIONNE, Auteur ; Richard E. TREMBLAY, Auteur ; Michel BOIVIN, Auteur . - p.277-289. Langues : Anglais (eng) in Development and Psychopathology > 25-2 (May 2013) . - p.277-289 Index. décimale : PER Périodiques Résumé : The study examined whether reciprocal friendship quantity or quality can mitigate genetic vulnerability for depression symptoms in children. The sample comprised 168 monozygotic twin pairs and 126 same-sex dizygotic twin pairs assessed in Grade 4 (mean age = 10.04 years). Friendship participation was measured via reciprocal nominations of close friendships within the classroom. Friendship quality was measured through self-reports. Depression symptoms were measured through teacher and peer reports. Genetic vulnerability for depression symptoms was unrelated to friendship participation or the number of reciprocal friends, but it was negatively related to positive friendship quality. In line with gene–environment interaction, genetic risk effects on depression symptoms were mitigated in girls who had at least one close reciprocal friend. In boys, only moderate main effects of genetic vulnerability and friendship participation were found but no interaction between them. However, among boys with at least one reciprocal friend, a greater number of friends was related to fewer depression symptoms whereas no cumulative effect of friendship was found for girls. Finally, positive friendship quality was related to fewer depression symptoms in girls and boys even when controlling for genetic risk. The findings emphasize the importance of teaching social interactional skills that promote high-quality friendship relations to help prevent the development of depression symptoms in children. En ligne : http://dx.doi.org/10.1017/S0954579412001058 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1995

Children's disruptiveness, peer rejection, friends'deviancy, and delinquent behaviors: A process-oriented approach / Frank VITARO in Development and Psychopathology, 19-2 (Spring 2007) 

Public ISBD [article]  in Development and Psychopathology > 19-2 (Spring 2007) . - p.433-453 Titre : Children's disruptiveness, peer rejection, friends'deviancy, and delinquent behaviors: A process-oriented approach Type de document : texte imprimé Auteurs : Frank VITARO, Auteur ; Sara PEDERSEN, Auteur ; Mara BRENDGEN, Auteur Article en page(s) : p.433-453 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : This study examined whether peer rejection and affiliation with deviant friends throughout childhood could mediate the link between early disruptiveness and two aspects of delinquent behaviors (i.e., violence and substance use) in a sample of 375 children. Furthermore, we tested whether the two putative mediators operated in a sequential manner or in a parallel manner. Participants' disruptiveness, peer rejection, and friends' deviancy were assessed throughout childhood (ages 7 to 13). Delinquency-related outcomes were assessed at ages 14 and 15 years. Results indicate that the sequential mediational model was supported when delinquency-related violence was the outcome, but not when substance use was the outcome. The discussion stresses the differential role of peer rejection and affiliation with deviant friends in regard to the two outcomes considered in this study and in regard to the time frame when they were measured. En ligne : http://dx.doi.org/10.1017/s0954579407070216 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1044 [article] Children's disruptiveness, peer rejection, friends'deviancy, and delinquent behaviors: A process-oriented approach [texte imprimé] / Frank VITARO, Auteur ; Sara PEDERSEN, Auteur ; Mara BRENDGEN, Auteur . - p.433-453. Langues : Anglais (eng) in Development and Psychopathology > 19-2 (Spring 2007) . - p.433-453 Index. décimale : PER Périodiques Résumé : This study examined whether peer rejection and affiliation with deviant friends throughout childhood could mediate the link between early disruptiveness and two aspects of delinquent behaviors (i.e., violence and substance use) in a sample of 375 children. Furthermore, we tested whether the two putative mediators operated in a sequential manner or in a parallel manner. Participants' disruptiveness, peer rejection, and friends' deviancy were assessed throughout childhood (ages 7 to 13). Delinquency-related outcomes were assessed at ages 14 and 15 years. Results indicate that the sequential mediational model was supported when delinquency-related violence was the outcome, but not when substance use was the outcome. The discussion stresses the differential role of peer rejection and affiliation with deviant friends in regard to the two outcomes considered in this study and in regard to the time frame when they were measured. En ligne : http://dx.doi.org/10.1017/s0954579407070216 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1044

Complex effects of dyslexia risk factors account for ADHD traits: evidence from two independent samples / Sara MASCHERETTI in Journal of Child Psychology and Psychiatry, 58-1 (January 2017) 

Public ISBD [article]  in Journal of Child Psychology and Psychiatry > 58-1 (January 2017) . - p.75-82 Titre : Complex effects of dyslexia risk factors account for ADHD traits: evidence from two independent samples Type de document : texte imprimé Auteurs : Sara MASCHERETTI, Auteur ; Vittoria TREZZI, Auteur ; Roberto GIORDA, Auteur ; Michel BOIVIN, Auteur ; Vickie PLOURDE, Auteur ; Frank VITARO, Auteur ; Mara BRENDGEN, Auteur ; Ginette DIONNE, Auteur ; Cecilia MARINO, Auteur Article en page(s) : p.75-82 Langues : Anglais (eng) Mots-clés : Developmental dyslexia  attention deficit/hyperactivity disorder  association study  gene-by-environment interaction  gene-by-gene interaction  pleiotropy Index. décimale : PER Périodiques Résumé : Background Developmental dyslexia (DD) and attention deficit/hyperactivity disorder (ADHD) are among the most common neurodevelopmental disorders, whose etiology involves multiple risk factors. DD and ADHD co-occur in the same individuals much more often than would be expected by chance. Several studies have found significant bivariate heritability, and specific genes associated with either DD or ADHD have been investigated for association in the other disorder. Moreover, there are likely to be gene-by-gene and gene-by-environment interaction effects (G × G and G × E, respectively) underlying the comorbidity between DD and ADHD. We investigated the pleiotropic effects of 19 SNPs spanning five DD genes (DYX1C1, DCDC2, KIAA0319, ROBO1, and GRIN2B) and seven DD environmental factors (smoke, miscarriage, birth weight, breastfeeding, parental age, socioeconomic status, and parental education) for main, either (a) genetic or (b) environmental, (c) G × G, and (d) G × E upon inattention and hyperactivity/impulsivity. We then attempted replication of these findings in an independent twin cohort. Methods Marker-trait association was analyzed by implementing the Quantitative Transmission Disequilibrium Test (QTDT). Environmental associations were tested by partial correlations. G × G were investigated by a general linear model equation and a family-based association test. G × E were analyzed through a general test for G × E in sib pair-based association analysis of quantitative traits. Results DCDC2-rs793862 was associated with hyperactivity/impulsivity via G × G (KIAA0319) and G × E (miscarriage). Smoke was significantly correlated with hyperactivity/impulsivity. We replicated the DCDC2 × KIAA0319 interaction upon hyperactivity/impulsivity in the twin cohort. Conclusions En ligne : http://dx.doi.org/10.1111/jcpp.12612 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2981 [article] Complex effects of dyslexia risk factors account for ADHD traits: evidence from two independent samples [texte imprimé] / Sara MASCHERETTI, Auteur ; Vittoria TREZZI, Auteur ; Roberto GIORDA, Auteur ; Michel BOIVIN, Auteur ; Vickie PLOURDE, Auteur ; Frank VITARO, Auteur ; Mara BRENDGEN, Auteur ; Ginette DIONNE, Auteur ; Cecilia MARINO, Auteur . - p.75-82. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 58-1 (January 2017) . - p.75-82 Mots-clés : Developmental dyslexia  attention deficit/hyperactivity disorder  association study  gene-by-environment interaction  gene-by-gene interaction  pleiotropy Index. décimale : PER Périodiques Résumé : Background Developmental dyslexia (DD) and attention deficit/hyperactivity disorder (ADHD) are among the most common neurodevelopmental disorders, whose etiology involves multiple risk factors. DD and ADHD co-occur in the same individuals much more often than would be expected by chance. Several studies have found significant bivariate heritability, and specific genes associated with either DD or ADHD have been investigated for association in the other disorder. Moreover, there are likely to be gene-by-gene and gene-by-environment interaction effects (G × G and G × E, respectively) underlying the comorbidity between DD and ADHD. We investigated the pleiotropic effects of 19 SNPs spanning five DD genes (DYX1C1, DCDC2, KIAA0319, ROBO1, and GRIN2B) and seven DD environmental factors (smoke, miscarriage, birth weight, breastfeeding, parental age, socioeconomic status, and parental education) for main, either (a) genetic or (b) environmental, (c) G × G, and (d) G × E upon inattention and hyperactivity/impulsivity. We then attempted replication of these findings in an independent twin cohort. Methods Marker-trait association was analyzed by implementing the Quantitative Transmission Disequilibrium Test (QTDT). Environmental associations were tested by partial correlations. G × G were investigated by a general linear model equation and a family-based association test. G × E were analyzed through a general test for G × E in sib pair-based association analysis of quantitative traits. Results DCDC2-rs793862 was associated with hyperactivity/impulsivity via G × G (KIAA0319) and G × E (miscarriage). Smoke was significantly correlated with hyperactivity/impulsivity. We replicated the DCDC2 × KIAA0319 interaction upon hyperactivity/impulsivity in the twin cohort. Conclusions En ligne : http://dx.doi.org/10.1111/jcpp.12612 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2981

Contribution of genes and environment to the longitudinal association between childhood impulsive-aggression and suicidality in adolescence / Massimiliano ORRI in Journal of Child Psychology and Psychiatry, 61-6 (June 2020) 

Public ISBD [article]  in Journal of Child Psychology and Psychiatry > 61-6 (June 2020) . - p.711-720 Titre : Contribution of genes and environment to the longitudinal association between childhood impulsive-aggression and suicidality in adolescence Type de document : texte imprimé Auteurs : Massimiliano ORRI, Auteur ; Marie-Claude GEOFFROY, Auteur ; Gustavo TURECKI, Auteur ; Bei FENG, Auteur ; Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; Ginette DIONNE, Auteur ; Stéphane PAQUIN, Auteur ; Cédric GALERA, Auteur ; Johanne RENAUD, Auteur ; Richard E TREMBLAY, Auteur ; Sylvana M COTE, Auteur ; Michel BOIVIN, Auteur Article en page(s) : p.711-720 Langues : Anglais (eng) Mots-clés : Suicide attempt  behavioral genetics  impulsive-aggression  longitudinal  suicidal ideation  twin study Index. décimale : PER Périodiques Résumé : BACKGROUND: Population-based and family studies showed that impulsive-aggression predicts suicidality; however, the underlying etiological nature of this association is poorly understood. The objective was to determine the contribution of genes and environment to the association between childhood impulsive-aggression and serious suicidal ideation/attempt in young adulthood. METHODS: N = 862 twins (435 families) from the Quebec Newborn Twin Study were followed up from birth to 20 years. Repeated measures of teacher-assessed impulsive-aggression were modeled using a genetically informed latent growth model including intercept and slope parameters reflecting individual differences in the baseline level (age 6 years) and in the change (increase/decrease) of impulsive-aggression during childhood (6 to 12 years), respectively. Lifetime suicidality (serious suicidal ideation/attempt) was self-reported at 20 years. Associations of impulsive-aggression intercept and slope with suicidality were decomposed into additive genetic (A) and unique environmental (E) components. RESULTS: Additive genetic factors accounted for an important part of individual differences in impulsive-aggression intercept (A = 90%, E = 10%) and slope (A = 65%, E = 35%). Genetic (50%) and unique environmental (50%) factors equally contributed to suicidality. We found that 38% of the genetic factors accounting for suicidality were shared with those underlying impulsive-aggression slope, whereas 40% of the environmental factors accounting for suicidality were shared with those associated with impulsive-aggression intercept. The genetic correlation between impulsive-aggression slope and suicidality was 0.60, p = .027. CONCLUSIONS: Genetic and unique environmental factors underlying suicidality significantly overlap with those underlying childhood impulsive-aggression. Future studies should identify putative genetic and environmental factors to inform prevention. En ligne : http://dx.doi.org/10.1111/jcpp.13163 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4261 [article] Contribution of genes and environment to the longitudinal association between childhood impulsive-aggression and suicidality in adolescence [texte imprimé] / Massimiliano ORRI, Auteur ; Marie-Claude GEOFFROY, Auteur ; Gustavo TURECKI, Auteur ; Bei FENG, Auteur ; Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; Ginette DIONNE, Auteur ; Stéphane PAQUIN, Auteur ; Cédric GALERA, Auteur ; Johanne RENAUD, Auteur ; Richard E TREMBLAY, Auteur ; Sylvana M COTE, Auteur ; Michel BOIVIN, Auteur . - p.711-720. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-6 (June 2020) . - p.711-720 Mots-clés : Suicide attempt  behavioral genetics  impulsive-aggression  longitudinal  suicidal ideation  twin study Index. décimale : PER Périodiques Résumé : BACKGROUND: Population-based and family studies showed that impulsive-aggression predicts suicidality; however, the underlying etiological nature of this association is poorly understood. The objective was to determine the contribution of genes and environment to the association between childhood impulsive-aggression and serious suicidal ideation/attempt in young adulthood. METHODS: N = 862 twins (435 families) from the Quebec Newborn Twin Study were followed up from birth to 20 years. Repeated measures of teacher-assessed impulsive-aggression were modeled using a genetically informed latent growth model including intercept and slope parameters reflecting individual differences in the baseline level (age 6 years) and in the change (increase/decrease) of impulsive-aggression during childhood (6 to 12 years), respectively. Lifetime suicidality (serious suicidal ideation/attempt) was self-reported at 20 years. Associations of impulsive-aggression intercept and slope with suicidality were decomposed into additive genetic (A) and unique environmental (E) components. RESULTS: Additive genetic factors accounted for an important part of individual differences in impulsive-aggression intercept (A = 90%, E = 10%) and slope (A = 65%, E = 35%). Genetic (50%) and unique environmental (50%) factors equally contributed to suicidality. We found that 38% of the genetic factors accounting for suicidality were shared with those underlying impulsive-aggression slope, whereas 40% of the environmental factors accounting for suicidality were shared with those associated with impulsive-aggression intercept. The genetic correlation between impulsive-aggression slope and suicidality was 0.60, p = .027. CONCLUSIONS: Genetic and unique environmental factors underlying suicidality significantly overlap with those underlying childhood impulsive-aggression. Future studies should identify putative genetic and environmental factors to inform prevention. En ligne : http://dx.doi.org/10.1111/jcpp.13163 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4261

Enduring effect of childhood maltreatment on cortisol and heart rate responses to stress: The moderating role of severity of experiences / Isabelle OUELLET-MORIN in Development and Psychopathology, 31-2 (May 2019) 

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Evidence of gene–environment correlation for peer difficulties: Disruptive behaviors predict early peer relation difficulties in school through genetic effects / Michel BOIVIN in Development and Psychopathology, 25-1 (February 2013) 

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Gene–environment interaction between peer victimization and child aggression / Mara BRENDGEN in Development and Psychopathology, 20-2 (Spring 2008) 

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Gene–environment interplay between peer rejection and depressive behavior in children / Mara BRENDGEN in Journal of Child Psychology and Psychiatry, 50-8 (August 2009) 

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Longitudinal Associations Between Clique Membership Status and Internalizing and Externalizing Problems During Late Childhood / Miranda WITVLIET in Journal of Clinical Child & Adolescent Psychology, 39-5 (September-October 2010) 

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Longitudinal links between impulsivity, gambling problems and depressive symptoms: a transactional model from adolescence to early adulthood / Frédéric DUSSAULT in Journal of Child Psychology and Psychiatry, 52-2 (February 2011) 

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Pathways explaining the reduction of adult criminal behaviour by a randomized preventive intervention for disruptive kindergarten children / Frank VITARO in Journal of Child Psychology and Psychiatry, 53-7 (July 2012) 

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Phenotypic and genetic associations between reading and attention-deficit/hyperactivity disorder dimensions in adolescence / Vickie PLOURDE in Development and Psychopathology, 29-4 (October 2017) 

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Phenotypic and genetic associations between reading comprehension, decoding skills, and ADHD dimensions: evidence from two population-based studies / Vickie PLOURDE in Journal of Child Psychology and Psychiatry, 56-10 (October 2015) 

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