Deconstructing the PDD clinical phenotype: internal validity of the DSM-IV / Luc LECAVALIER in Journal of Child Psychology and Psychiatry, 50-10 (October 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-10 (October 2009) . - p.1246-1254 Titre : Deconstructing the PDD clinical phenotype: internal validity of the DSM-IV Type de document : Texte imprimé et/ou numérique Auteurs : Luc LECAVALIER, Auteur ; Kenneth D. GADOW, Auteur ; Carla DEVINCENT, Auteur ; Michael C. EDWARDS, Auteur ; Carrie HOUTS, Auteur Année de publication : 2009 Article en page(s) : p.1246-1254 Langues : Anglais (eng) Mots-clés : Validity autism pervasive-developmental-disorder psychiatric-disorder nosology factor-analysis Index. décimale : PER Périodiques Résumé : Background: Empirical studies of the structure of autism symptoms have challenged the three-domain model of impairment currently characterizing pervasive developmental disorders (PDD). The objective of this study was to assess the internal validity of the DSM as a conceptual model for describing PDD, while paying particular attention to certain subject characteristics. Methods: Parents and teachers completed a DSM-IV-referenced rating scale for 3- to 12-year-old clinic referrals with a PDD (n = 730). Ratings were submitted to confirmatory factor analysis and different models were assessed for fit. Results: Measures of fit indicated that the three-factor solution based on the DSM was superior to other models. Most indices of fit were acceptable, but showed room for improvement. Fit indices varied according to the rater (parent or teacher), child's age (preschool versus school aged), PDD subtype (autism, Asperger's, pervasive developmental disorder not otherwise specified (PDDNOS)), and IQ. Conclusions: More research needs to be done before discarding current classification systems. Subject characteristics, modality of assessment, and procedural variations in statistical analyses impact conclusions about the structure of PDD symptoms. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02104.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=838 [article] Deconstructing the PDD clinical phenotype: internal validity of the DSM-IV [Texte imprimé et/ou numérique] / Luc LECAVALIER, Auteur ; Kenneth D. GADOW, Auteur ; Carla DEVINCENT, Auteur ; Michael C. EDWARDS, Auteur ; Carrie HOUTS, Auteur . - 2009 . - p.1246-1254. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-10 (October 2009) . - p.1246-1254 Mots-clés : Validity autism pervasive-developmental-disorder psychiatric-disorder nosology factor-analysis Index. décimale : PER Périodiques Résumé : Background: Empirical studies of the structure of autism symptoms have challenged the three-domain model of impairment currently characterizing pervasive developmental disorders (PDD). The objective of this study was to assess the internal validity of the DSM as a conceptual model for describing PDD, while paying particular attention to certain subject characteristics. Methods: Parents and teachers completed a DSM-IV-referenced rating scale for 3- to 12-year-old clinic referrals with a PDD (n = 730). Ratings were submitted to confirmatory factor analysis and different models were assessed for fit. Results: Measures of fit indicated that the three-factor solution based on the DSM was superior to other models. Most indices of fit were acceptable, but showed room for improvement. Fit indices varied according to the rater (parent or teacher), child's age (preschool versus school aged), PDD subtype (autism, Asperger's, pervasive developmental disorder not otherwise specified (PDDNOS)), and IQ. Conclusions: More research needs to be done before discarding current classification systems. Subject characteristics, modality of assessment, and procedural variations in statistical analyses impact conclusions about the structure of PDD symptoms. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02104.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=838

The structure of the Autism Diagnostic Interview-Revised: diagnostic and phenotypic implications / Anne V. SNOW in Journal of Child Psychology and Psychiatry, 50-6 (June 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-6 (June 2009) . - p.734-742 Titre : The structure of the Autism Diagnostic Interview-Revised: diagnostic and phenotypic implications Type de document : Texte imprimé et/ou numérique Auteurs : Anne V. SNOW, Auteur ; Luc LECAVALIER, Auteur ; Carrie HOUTS, Auteur Année de publication : 2009 Article en page(s) : p.734-742 Langues : Anglais (eng) Mots-clés : Autistic-disorder pervasive-developmental-disorder assessment factor-analysis classification Index. décimale : PER Périodiques Résumé : Background: Multivariate statistics can assist in refining the nosology and diagnosis of pervasive developmental disorders (PDD) and also contribute important information for genetic studies. The Autism Diagnostic Interview-Revised (ADI-R) is one of the most widely used assessment instruments in the field of PDD. The current study investigated its factor structure and convergence with measures of adaptive, language, and intellectual functioning. Methods: Analyses were conducted on 1,861 individuals with PDD between the ages of 4 and 18 years (mean = 8.3, SD = 3.2). ADI-R scores were submitted to confirmatory factor analysis (CFA) and exploratory factor analysis (EFA). Analyses were conducted according to verbal status (n = 1,329 verbal, n = 532 nonverbal) and separately for algorithm items only and for all items. ADI-R scores were correlated with scores on measures of adaptive, language, and intellectual functioning. Results: Several factor solutions were examined and compared. CFAs suggested that two- and three-factor solutions were similar, and slightly superior to a one-factor solution. EFAs and measures of internal consistency provided some support for a two-factor solution consisting of social and communication behaviors and restricted and repetitive behaviors. Measures of functioning were not associated with ADI-R domain scores in nonverbal children, but negatively correlated in verbal children. Conclusions: Overall, data suggested that autism symptomatology can be explained statistically with a two-domain model. It also pointed to different symptoms susceptible to be helpful in linkage analyses. Implications of a two-factor model are discussed. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02018.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=756 [article] The structure of the Autism Diagnostic Interview-Revised: diagnostic and phenotypic implications [Texte imprimé et/ou numérique] / Anne V. SNOW, Auteur ; Luc LECAVALIER, Auteur ; Carrie HOUTS, Auteur . - 2009 . - p.734-742. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-6 (June 2009) . - p.734-742 Mots-clés : Autistic-disorder pervasive-developmental-disorder assessment factor-analysis classification Index. décimale : PER Périodiques Résumé : Background: Multivariate statistics can assist in refining the nosology and diagnosis of pervasive developmental disorders (PDD) and also contribute important information for genetic studies. The Autism Diagnostic Interview-Revised (ADI-R) is one of the most widely used assessment instruments in the field of PDD. The current study investigated its factor structure and convergence with measures of adaptive, language, and intellectual functioning. Methods: Analyses were conducted on 1,861 individuals with PDD between the ages of 4 and 18 years (mean = 8.3, SD = 3.2). ADI-R scores were submitted to confirmatory factor analysis (CFA) and exploratory factor analysis (EFA). Analyses were conducted according to verbal status (n = 1,329 verbal, n = 532 nonverbal) and separately for algorithm items only and for all items. ADI-R scores were correlated with scores on measures of adaptive, language, and intellectual functioning. Results: Several factor solutions were examined and compared. CFAs suggested that two- and three-factor solutions were similar, and slightly superior to a one-factor solution. EFAs and measures of internal consistency provided some support for a two-factor solution consisting of social and communication behaviors and restricted and repetitive behaviors. Measures of functioning were not associated with ADI-R domain scores in nonverbal children, but negatively correlated in verbal children. Conclusions: Overall, data suggested that autism symptomatology can be explained statistically with a two-domain model. It also pointed to different symptoms susceptible to be helpful in linkage analyses. Implications of a two-factor model are discussed. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02018.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=756

Validity of DSM-IV syndromes in preschoolers with autism spectrum disorders / Luc LECAVALIER in Autism, 15-5 (September 2011)  

Public ISBD [article]  inAutism > 15-5 (September 2011) . - p.527-543 Titre : Validity of DSM-IV syndromes in preschoolers with autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Luc LECAVALIER, Auteur ; Kenneth D. GADOW, Auteur ; Carla DEVINCENT, Auteur ; Carrie HOUTS, Auteur ; Michael C. EDWARDS, Auteur Année de publication : 2011 Article en page(s) : p.527-543 Langues : Anglais (eng) Mots-clés : autism  autism spectrum disorder  factor analysis  nosology  psychiatric disorder  preschoolers  validity Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1177/1362361310391115 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=144 [article] Validity of DSM-IV syndromes in preschoolers with autism spectrum disorders [Texte imprimé et/ou numérique] / Luc LECAVALIER, Auteur ; Kenneth D. GADOW, Auteur ; Carla DEVINCENT, Auteur ; Carrie HOUTS, Auteur ; Michael C. EDWARDS, Auteur . - 2011 . - p.527-543. Langues : Anglais (eng) in Autism > 15-5 (September 2011) . - p.527-543 Mots-clés : autism  autism spectrum disorder  factor analysis  nosology  psychiatric disorder  preschoolers  validity Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1177/1362361310391115 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=144

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