[article]
| Titre : |
The Effect of Methylphenidate and Clonidine on Response Inhibition and State Regulation in Children with ADHD |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Jaap VAN DER MEERE, Auteur ; Boudewijn GUNNING, Auteur ; Nanke STEMERDINK, Auteur |
| Année de publication : |
1999 |
| Article en page(s) : |
p.291-298 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Hyperactivity Attention Deficit Disorder school children methylphenidate clonidine |
| Index. décimale : |
PER Périodiques |
| Résumé : |
The goal of this study was to evaluate the effect of methylphenidate (MPH) and clonidine in comparison with placebo on response inhibition and state regulation in children with Attention Deficit Hyperactivity Disorder (ADHD). The study utilised a double-blind crossover design in which children were randomly assigned without replacement to placebo, MPH, and clonidine following baseline assessment. The primary dependent measures were derived from children's performance (reaction time and errors) on a GO-NO GO task under three conditions that altered the inter-stimulus interval (ISI) for presented GO-NO GO stimuli: ISI of 1 sec (fast condition), 4 sec (medium condition), and 8 sec (slow condition). Findings indicated no difference in task performance between groups treated for 7 weeks with placebo, MPH, and clonidine. We concluded that the state regulation problem in ADHD is resistant to MPH and clonidine. |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124 |
in Journal of Child Psychology and Psychiatry > 40-2 (February 1999) . - p.291-298
[article] The Effect of Methylphenidate and Clonidine on Response Inhibition and State Regulation in Children with ADHD [Texte imprimé et/ou numérique] / Jaap VAN DER MEERE, Auteur ; Boudewijn GUNNING, Auteur ; Nanke STEMERDINK, Auteur . - 1999 . - p.291-298. Langues : Anglais ( eng) in Journal of Child Psychology and Psychiatry > 40-2 (February 1999) . - p.291-298
| Mots-clés : |
Hyperactivity Attention Deficit Disorder school children methylphenidate clonidine |
| Index. décimale : |
PER Périodiques |
| Résumé : |
The goal of this study was to evaluate the effect of methylphenidate (MPH) and clonidine in comparison with placebo on response inhibition and state regulation in children with Attention Deficit Hyperactivity Disorder (ADHD). The study utilised a double-blind crossover design in which children were randomly assigned without replacement to placebo, MPH, and clonidine following baseline assessment. The primary dependent measures were derived from children's performance (reaction time and errors) on a GO-NO GO task under three conditions that altered the inter-stimulus interval (ISI) for presented GO-NO GO stimuli: ISI of 1 sec (fast condition), 4 sec (medium condition), and 8 sec (slow condition). Findings indicated no difference in task performance between groups treated for 7 weeks with placebo, MPH, and clonidine. We concluded that the state regulation problem in ADHD is resistant to MPH and clonidine. |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124 |
|
The Effect of Methylphenidate and Clonidine on Response Inhibition and State Regulation in Children with ADHD in Journal of Child Psychology and Psychiatry, 40-2 (February 1999)