[article] 
inJournal of Autism and Developmental Disorders > 41-7 (July 2011) . - p.837-847

Titre :	Differential Olfactory Identification in Children with Autism and Asperger’s Disorder: A Comparative and Longitudinal Study
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Tamara MAY, Auteur ; Warrick J. BREWER, Auteur ; Nicole J. RINEHART, Auteur ; Peter G. ENTICOTT, Auteur ; Avril V. BRERETON, Auteur ; Bruce J. TONGE, Auteur
Année de publication :	2011
Article en page(s) :	p.837-847
Langues :	Anglais (eng)
Mots-clés :	High-functioning autism  Asperger’s disorder  Olfactory identification  UPSIT
Index. décimale :	PER Périodiques
Résumé :	Key theories of autism implicate orbitofrontal cortex (OFC) compromise, while olfactory identification (OI) deficits are associated with OFC dysfunction. This study aimed to complete a 5-year follow-up of children with high-functioning autism (HFA) who previously lacked the normal age-OI association; and compare unirhinal-OI in children with HFA, Asperger’s disorder (ASP), and controls. While both HFA and controls had improved birhinal-OI at follow-up, reduced OI in some HFA participants suggested OFC deterioration and heterogeneous OFC development. Unirhinal-OI was impaired in HFA but not ASP relative to controls, suggesting orbitofrontal compromise in HFA but integrity in ASP. Differing IQ-OI relationships existed between HFA and ASP. Findings support the hypothesis of separate neurobiological underpinnings in ASP and HFA, specifically differential orbitofrontal functioning.
En ligne :	http://dx.doi.org/10.1007/s10803-010-1101-0
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=130

[article] Differential Olfactory Identification in Children with Autism and Asperger’s Disorder: A Comparative and Longitudinal Study [Texte imprimé et/ou numérique] / Tamara MAY, Auteur ; Warrick J. BREWER, Auteur ; Nicole J. RINEHART, Auteur ; Peter G. ENTICOTT, Auteur ; Avril V. BRERETON, Auteur ; Bruce J. TONGE, Auteur . - 2011 . - p.837-847.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-7 (July 2011) . - p.837-847

Mots-clés :	High-functioning autism  Asperger’s disorder  Olfactory identification  UPSIT
Index. décimale :	PER Périodiques
Résumé :	Key theories of autism implicate orbitofrontal cortex (OFC) compromise, while olfactory identification (OI) deficits are associated with OFC dysfunction. This study aimed to complete a 5-year follow-up of children with high-functioning autism (HFA) who previously lacked the normal age-OI association; and compare unirhinal-OI in children with HFA, Asperger’s disorder (ASP), and controls. While both HFA and controls had improved birhinal-OI at follow-up, reduced OI in some HFA participants suggested OFC deterioration and heterogeneous OFC development. Unirhinal-OI was impaired in HFA but not ASP relative to controls, suggesting orbitofrontal compromise in HFA but integrity in ASP. Differing IQ-OI relationships existed between HFA and ASP. Findings support the hypothesis of separate neurobiological underpinnings in ASP and HFA, specifically differential orbitofrontal functioning.
En ligne :	http://dx.doi.org/10.1007/s10803-010-1101-0
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=130