Erratum to: Prenatal and Perinatal Risk Factors for Autism in China / Xin ZHANG in Journal of Autism and Developmental Disorders, 40-11 (November 2010)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 40-11 (November 2010) . - p.1322 Titre : Erratum to: Prenatal and Perinatal Risk Factors for Autism in China Type de document : Texte imprimé et/ou numérique Auteurs : Xin ZHANG, Auteur ; Cong-Chao LV, Auteur ; Jiang TIAN, Auteur ; Ru-Juan MIAO, Auteur ; Wei XI, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Lihong QI, Auteur Année de publication : 2010 Article en page(s) : p.1322 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-010-1020-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=113 [article] Erratum to: Prenatal and Perinatal Risk Factors for Autism in China [Texte imprimé et/ou numérique] / Xin ZHANG, Auteur ; Cong-Chao LV, Auteur ; Jiang TIAN, Auteur ; Ru-Juan MIAO, Auteur ; Wei XI, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Lihong QI, Auteur . - 2010 . - p.1322. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 40-11 (November 2010) . - p.1322 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-010-1020-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=113

MAOA, DBH, and SLC6A4 variants in CHARGE: a case–control study of autism spectrum disorders / Flora TASSONE in Autism Research, 4-4 (August 2011)  

Public ISBD [article]  inAutism Research > 4-4 (August 2011) . - p.250-261 Titre : MAOA, DBH, and SLC6A4 variants in CHARGE: a case–control study of autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Flora TASSONE, Auteur ; Lihong QI, Auteur ; Wenting ZHANG, Auteur ; David J. HANSEN, Auteur ; Isaac N. PESSAH, Auteur ; Irva HERTZ-PICCIOTTO, Auteur Année de publication : 2011 Article en page(s) : p.250-261 Langues : Anglais (eng) Mots-clés : ASD  polymorphisms  SLC6A4  MAOA  DBH Index. décimale : PER Périodiques Résumé : Genetic factors are established to contribute to the development of autism. We examined three loci, serotonin transporter (SLC6A4), dopamine β-hydroxylase (DBH), and the variable number of tandem repeat promoter of the monoamine oxidase A (MAOA) for association with autism in participants from the Childhood Autism Risks from Genetics and the Environment (CHARGE ) Study, the first large-scale population-based case–control investigation of both environmental and genetic contributions to autism risk. Among male children enrolled in the CHARGE study we tested associations between each of the three polymorphisms and autism (AU) (n = 119), or a combined group of autism and other autism spectrum disorders (AU+ASD, which includes an additional n = 53) as compared with typically developing controls (TD, n = 137). The case–control association analysis showed neither SLC6A4 nor DBH to be statistically significantly associated with AU or ASD. However, the male children carrying 4 tandem repeats in the promoter region of the MAOA gene showed a two-fold higher risk of AU (or AU+ASD) than those carrying allele 3, adjusted for confounders (OR = 2.02, 95% CI = 1.12, 3.65, P = 0.02 for AU vs. TD, and OR = 2.05, 95% CI = 1.19, 3.53, P = 0.01 for ASD vs. TD). In addition, children of mothers homozygous for the 4 tandem repeat allele showed at least a three-fold higher risk of AU (or AU+ASD) than those with mothers homozygous for allele 3 (OR = 3.07, 95% CI = 1.19, 7.91, P = 0.02 for AU vs. TD, and OR = 3.26, 95% CI = 1.35, 7.89, P = 0.009 for AU+ASD vs. TD). These results suggest a potential role of the functional MAOA promoter alleles in the male child, the mother, or both in ASD. En ligne : http://dx.doi.org/10.1002/aur.196 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=141 [article] MAOA, DBH, and SLC6A4 variants in CHARGE: a case–control study of autism spectrum disorders [Texte imprimé et/ou numérique] / Flora TASSONE, Auteur ; Lihong QI, Auteur ; Wenting ZHANG, Auteur ; David J. HANSEN, Auteur ; Isaac N. PESSAH, Auteur ; Irva HERTZ-PICCIOTTO, Auteur . - 2011 . - p.250-261. Langues : Anglais (eng) in Autism Research > 4-4 (August 2011) . - p.250-261 Mots-clés : ASD  polymorphisms  SLC6A4  MAOA  DBH Index. décimale : PER Périodiques Résumé : Genetic factors are established to contribute to the development of autism. We examined three loci, serotonin transporter (SLC6A4), dopamine β-hydroxylase (DBH), and the variable number of tandem repeat promoter of the monoamine oxidase A (MAOA) for association with autism in participants from the Childhood Autism Risks from Genetics and the Environment (CHARGE ) Study, the first large-scale population-based case–control investigation of both environmental and genetic contributions to autism risk. Among male children enrolled in the CHARGE study we tested associations between each of the three polymorphisms and autism (AU) (n = 119), or a combined group of autism and other autism spectrum disorders (AU+ASD, which includes an additional n = 53) as compared with typically developing controls (TD, n = 137). The case–control association analysis showed neither SLC6A4 nor DBH to be statistically significantly associated with AU or ASD. However, the male children carrying 4 tandem repeats in the promoter region of the MAOA gene showed a two-fold higher risk of AU (or AU+ASD) than those carrying allele 3, adjusted for confounders (OR = 2.02, 95% CI = 1.12, 3.65, P = 0.02 for AU vs. TD, and OR = 2.05, 95% CI = 1.19, 3.53, P = 0.01 for ASD vs. TD). In addition, children of mothers homozygous for the 4 tandem repeat allele showed at least a three-fold higher risk of AU (or AU+ASD) than those with mothers homozygous for allele 3 (OR = 3.07, 95% CI = 1.19, 7.91, P = 0.02 for AU vs. TD, and OR = 3.26, 95% CI = 1.35, 7.89, P = 0.009 for AU+ASD vs. TD). These results suggest a potential role of the functional MAOA promoter alleles in the male child, the mother, or both in ASD. En ligne : http://dx.doi.org/10.1002/aur.196 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=141

Prenatal and Perinatal Risk Factors for Autism in China / Xin ZHANG in Journal of Autism and Developmental Disorders, 40-11 (November 2010)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 40-11 (November 2010) . - p.1311-1321 Titre : Prenatal and Perinatal Risk Factors for Autism in China Type de document : Texte imprimé et/ou numérique Auteurs : Xin ZHANG, Auteur ; Cong-Chao LV, Auteur ; Jiang TIAN, Auteur ; Ru-Juan MIAO, Auteur ; Wei XI, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Lihong QI, Auteur Année de publication : 2010 Article en page(s) : p.1311-1321 Langues : Anglais (eng) Mots-clés : Autism  China  Prenatal  Perinatal  Risk factors Index. décimale : PER Périodiques Résumé : We conducted a case–control study using 190 Han children with and without autism to investigate prenatal and perinatal risk factors for autism in China. Cases were recruited through public special education schools and controls from regular public schools in the same region (Tianjin), with frequency matching on sex and birth year. Unadjusted analyses identified seven prenatal and seven perinatal risk factors significantly associated with autism. In the adjusted analysis, nine risk factors showed significant association with autism: maternal second-hand smoke exposure, maternal chronic or acute medical conditions unrelated to pregnancy, maternal unhappy emotional state, gestational complications, edema, abnormal gestational age (<35 or >42 weeks), nuchal cord, gravidity >1, and advanced paternal age at delivery (>30 year-old). En ligne : http://dx.doi.org/10.1007/s10803-010-0992-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=113 [article] Prenatal and Perinatal Risk Factors for Autism in China [Texte imprimé et/ou numérique] / Xin ZHANG, Auteur ; Cong-Chao LV, Auteur ; Jiang TIAN, Auteur ; Ru-Juan MIAO, Auteur ; Wei XI, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Lihong QI, Auteur . - 2010 . - p.1311-1321. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 40-11 (November 2010) . - p.1311-1321 Mots-clés : Autism  China  Prenatal  Perinatal  Risk factors Index. décimale : PER Périodiques Résumé : We conducted a case–control study using 190 Han children with and without autism to investigate prenatal and perinatal risk factors for autism in China. Cases were recruited through public special education schools and controls from regular public schools in the same region (Tianjin), with frequency matching on sex and birth year. Unadjusted analyses identified seven prenatal and seven perinatal risk factors significantly associated with autism. In the adjusted analysis, nine risk factors showed significant association with autism: maternal second-hand smoke exposure, maternal chronic or acute medical conditions unrelated to pregnancy, maternal unhappy emotional state, gestational complications, edema, abnormal gestational age (<35 or >42 weeks), nuchal cord, gravidity >1, and advanced paternal age at delivery (>30 year-old). En ligne : http://dx.doi.org/10.1007/s10803-010-0992-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=113

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