[article] 
inJournal of Autism and Developmental Disorders > 42-4 (April 2012) . - p.625-633

Titre :	The Autism-Spectrum Quotient—Italian Version: A Cross-Cultural Confirmation of the Broader Autism Phenotype
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Liliana RUTA, Auteur ; Domenico MAZZONE, Auteur ; Luigi MAZZONE, Auteur ; Sally WHEELWRIGHT, Auteur ; Simon BARON-COHEN, Auteur
Année de publication :	2012
Article en page(s) :	p.625-633
Langues :	Anglais (eng)
Mots-clés :	Autism spectrum conditions  Broader autism phenotype  Autistic traits  Autism-spectrum quotient
Index. décimale :	PER Périodiques
Résumé :	The Autism Spectrum Quotient (AQ) has been used to define the ‘broader’ (BAP), ‘medium’ (MAP) and ‘narrow’ autism phenotypes (NAP). We used a new Italian version of the AQ to test if difference on AQ scores and the distribution of BAP, MAP and NAP in autism parents (n = 245) versus control parents (n = 300) were replicated in a Sicilian sample. Parents of children with autism spectrum conditions scored higher than the control parents on total AQ, social skills and communication subscales, and exhibited higher rates of BAP, MAP and NAP. We conclude that the Italian AQ is a cross-culturally reliable measure of these different phenotypes, and can be used to identify a phenotypic gradient of severity of autistic traits in families. To understand the molecular basis of these phenotypes will require its use in genetic association studies.
En ligne :	http://dx.doi.org/10.1007/s10803-011-1290-1
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154

[article] The Autism-Spectrum Quotient—Italian Version: A Cross-Cultural Confirmation of the Broader Autism Phenotype [Texte imprimé et/ou numérique] / Liliana RUTA, Auteur ; Domenico MAZZONE, Auteur ; Luigi MAZZONE, Auteur ; Sally WHEELWRIGHT, Auteur ; Simon BARON-COHEN, Auteur . - 2012 . - p.625-633.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-4 (April 2012) . - p.625-633

Mots-clés :	Autism spectrum conditions  Broader autism phenotype  Autistic traits  Autism-spectrum quotient
Index. décimale :	PER Périodiques
Résumé :	The Autism Spectrum Quotient (AQ) has been used to define the ‘broader’ (BAP), ‘medium’ (MAP) and ‘narrow’ autism phenotypes (NAP). We used a new Italian version of the AQ to test if difference on AQ scores and the distribution of BAP, MAP and NAP in autism parents (n = 245) versus control parents (n = 300) were replicated in a Sicilian sample. Parents of children with autism spectrum conditions scored higher than the control parents on total AQ, social skills and communication subscales, and exhibited higher rates of BAP, MAP and NAP. We conclude that the Italian AQ is a cross-culturally reliable measure of these different phenotypes, and can be used to identify a phenotypic gradient of severity of autistic traits in families. To understand the molecular basis of these phenotypes will require its use in genetic association studies.
En ligne :	http://dx.doi.org/10.1007/s10803-011-1290-1
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154