A Case-comparison Study of the Characteristics of Children with a Short Stature Syndrome Induced by Stress (Hyperphagic Short Stature) and a Consecutive Series of Unaffected “Stressed” Children / Jane GILMOUR in Journal of Child Psychology and Psychiatry, 40-6 (September 1999)

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 40-6 (September 1999) . - p.969-978 Titre : A Case-comparison Study of the Characteristics of Children with a Short Stature Syndrome Induced by Stress (Hyperphagic Short Stature) and a Consecutive Series of Unaffected “Stressed” Children Type de document : Texte imprimé et/ou numérique Auteurs : Jane GILMOUR, Auteur ; David H. SKUSE, Auteur Année de publication : 1999 Article en page(s) : p.969-978 Langues : Anglais (eng) Mots-clés : Behaviour problems  distress  eating behaviour  endocrinology  growth retardation Index. décimale : PER Périodiques Résumé : Recently a type of growth failure (Hyperphagic Short Stature) has been described, in which there is potentially reversible severe impairment of growth hormone secretion, in association with excessively high levels of psychosocial stress. This condition is a variant of the disorder formerly known as Psychosocial Dwarfism. In the present study we compared children with Hyperphagic Short Stature (N= 25, aged 9.04 years±3.78, 72% male) and a closely matched sample with normal height, drawn from comparably stressful family circumstances (N= 25, aged 10.61±3.04, 60% male). Measures of the psychosocial environment, anthropometry, and developmental history from infancy were obtained. Many symptoms thought previously to be characteristics of psychosocial dwarfism were found to be nonspecific stress responses. Hypotonia (p < .05), enuresis/encopresis (p < .01), and sleep cycle disruption (p < .05) did differentiate the groups. Growth, appetite, and sleep are all influenced by hypothalamic nuclei, suggesting hypothalamic pathology could account for most of the clinical features of Hyperphagic Short Stature. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124 [article] A Case-comparison Study of the Characteristics of Children with a Short Stature Syndrome Induced by Stress (Hyperphagic Short Stature) and a Consecutive Series of Unaffected “Stressed” Children [Texte imprimé et/ou numérique] / Jane GILMOUR, Auteur ; David H. SKUSE, Auteur . - 1999 . - p.969-978. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 40-6 (September 1999) . - p.969-978 Mots-clés : Behaviour problems  distress  eating behaviour  endocrinology  growth retardation Index. décimale : PER Périodiques Résumé : Recently a type of growth failure (Hyperphagic Short Stature) has been described, in which there is potentially reversible severe impairment of growth hormone secretion, in association with excessively high levels of psychosocial stress. This condition is a variant of the disorder formerly known as Psychosocial Dwarfism. In the present study we compared children with Hyperphagic Short Stature (N= 25, aged 9.04 years±3.78, 72% male) and a closely matched sample with normal height, drawn from comparably stressful family circumstances (N= 25, aged 10.61±3.04, 60% male). Measures of the psychosocial environment, anthropometry, and developmental history from infancy were obtained. Many symptoms thought previously to be characteristics of psychosocial dwarfism were found to be nonspecific stress responses. Hypotonia (p < .05), enuresis/encopresis (p < .01), and sleep cycle disruption (p < .05) did differentiate the groups. Growth, appetite, and sleep are all influenced by hypothalamic nuclei, suggesting hypothalamic pathology could account for most of the clinical features of Hyperphagic Short Stature. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124

Toward specifying pervasive developmental disorder—not otherwise specified / William P.L. MANDY in Autism Research, 4-2 (April 2011)  

Public ISBD [article]  inAutism Research > 4-2 (April 2011) . - p.121-131 Titre : Toward specifying pervasive developmental disorder—not otherwise specified Type de document : Texte imprimé et/ou numérique Auteurs : William P.L. MANDY, Auteur ; Tony CHARMAN, Auteur ; Jane GILMOUR, Auteur ; David H. SKUSE, Auteur Année de publication : 2011 Article en page(s) : p.121-131 Langues : Anglais (eng) Mots-clés : pervasive developmental disorder—not otherwise specified (PDD-NOS)  Autistic disorder  Asperger's disorder  autism spectrum disorder  diagnostic and statistical manual (DSM) Index. décimale : PER Périodiques Résumé : Pervasive developmental disorder—not otherwise specified (PDD-NOS) is the most common and least satisfactory of the PDD diagnoses. It is not formally operationalized, which limits its reliability and has hampered attempts to assess its validity. We aimed, first, to improve the reliability and replicability of PDD-NOS by operationalizing its DSM-IV-TR description and, second, to test its validity through comparison with autistic disorder (AD) and Asperger's disorder (AsD). In a sample of 256 young people (mean age = 9.1 years) we used Developmental, Diagnostic and Dimensional (3Di) algorithmic analysis to classify DSM-IV-TR AD (n = 97), AsD (n = 93) and PDD-NOS (n = 66). Groups were compared on independent measures of core PDD symptomatology, associated autistic features, and intelligence. Contrary to the assumption that PDD-NOS is heterogeneous, almost all (97%) of those with PDD-NOS had one distinct symptom pattern, namely impairments in social reciprocity and communication, without significant repetitive and stereotyped behaviors (RSB). Compared to AD and AsD, they had comparably severe but more circumscribed social communication difficulties, with fewer non-social features of autism, such as sensory, feeding and visuo-spatial problems. These individuals appear to have a distinct variant of autism that does not merely sit at the less severe end of the same continuum of symptoms. The current draft guidelines for DSM-V, which mandate the presence of RSBs for any PDD diagnosis, would exclude such people from the autistic spectrum. En ligne : http://dx.doi.org/10.1002/aur.178 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 [article] Toward specifying pervasive developmental disorder—not otherwise specified [Texte imprimé et/ou numérique] / William P.L. MANDY, Auteur ; Tony CHARMAN, Auteur ; Jane GILMOUR, Auteur ; David H. SKUSE, Auteur . - 2011 . - p.121-131. Langues : Anglais (eng) in Autism Research > 4-2 (April 2011) . - p.121-131 Mots-clés : pervasive developmental disorder—not otherwise specified (PDD-NOS)  Autistic disorder  Asperger's disorder  autism spectrum disorder  diagnostic and statistical manual (DSM) Index. décimale : PER Périodiques Résumé : Pervasive developmental disorder—not otherwise specified (PDD-NOS) is the most common and least satisfactory of the PDD diagnoses. It is not formally operationalized, which limits its reliability and has hampered attempts to assess its validity. We aimed, first, to improve the reliability and replicability of PDD-NOS by operationalizing its DSM-IV-TR description and, second, to test its validity through comparison with autistic disorder (AD) and Asperger's disorder (AsD). In a sample of 256 young people (mean age = 9.1 years) we used Developmental, Diagnostic and Dimensional (3Di) algorithmic analysis to classify DSM-IV-TR AD (n = 97), AsD (n = 93) and PDD-NOS (n = 66). Groups were compared on independent measures of core PDD symptomatology, associated autistic features, and intelligence. Contrary to the assumption that PDD-NOS is heterogeneous, almost all (97%) of those with PDD-NOS had one distinct symptom pattern, namely impairments in social reciprocity and communication, without significant repetitive and stereotyped behaviors (RSB). Compared to AD and AsD, they had comparably severe but more circumscribed social communication difficulties, with fewer non-social features of autism, such as sensory, feeding and visuo-spatial problems. These individuals appear to have a distinct variant of autism that does not merely sit at the less severe end of the same continuum of symptoms. The current draft guidelines for DSM-V, which mandate the presence of RSBs for any PDD diagnosis, would exclude such people from the autistic spectrum. En ligne : http://dx.doi.org/10.1002/aur.178 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121

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