[article] inJournal of Autism and Developmental Disorders > 42-8 (August 2012) . - p.1630-1641
Titre : |
Exploring the Relationship Between Autism Spectrum Disorder and Epilepsy Using Latent Class Cluster Analysis |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Michael L. CUCCARO, Auteur ; Roberto TUCHMAN, Auteur ; Kara L. HAMILTON-NELSON, Auteur ; Harry H. WRIGHT, Auteur ; Ruth K. ABRAMSON, Auteur ; Jonathan L. HAINES, Auteur ; John R. GILBERT, Auteur ; Margaret A. O. PERICAK-VANCE, Auteur |
Année de publication : |
2012 |
Article en page(s) : |
p.1630-1641 |
Langues : |
Anglais (eng) |
Mots-clés : |
Autism spectrum disorders Epilepsy Latent class cluster analysis Phenotype |
Index. décimale : |
PER Périodiques |
Résumé : |
Epilepsy co-occurs frequently in autism spectrum disorders (ASD). Understanding this co-occurrence requires a better understanding of the ASD-epilepsy phenotype (or phenotypes). To address this, we conducted latent class cluster analysis (LCCA) on an ASD dataset (N = 577) which included 64 individuals with epilepsy. We identified a 5-cluster solution with one cluster showing a high rate of epilepsy (29%), earlier age at first recognition, and high rates of repetitive object use and unusual sensory interests. We also conducted LCCA on an ASD-epilepsy subset from the overall dataset (N = 64) which yielded three clusters, the largest of which had impairments in language and motor development; the remaining clusters, while not as developmentally impaired were characterized by different levels of repetitive and sensory behaviors. |
En ligne : |
http://dx.doi.org/10.1007/s10803-011-1402-y |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178 |
[article] Exploring the Relationship Between Autism Spectrum Disorder and Epilepsy Using Latent Class Cluster Analysis [Texte imprimé et/ou numérique] / Michael L. CUCCARO, Auteur ; Roberto TUCHMAN, Auteur ; Kara L. HAMILTON-NELSON, Auteur ; Harry H. WRIGHT, Auteur ; Ruth K. ABRAMSON, Auteur ; Jonathan L. HAINES, Auteur ; John R. GILBERT, Auteur ; Margaret A. O. PERICAK-VANCE, Auteur . - 2012 . - p.1630-1641. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 42-8 (August 2012) . - p.1630-1641
Mots-clés : |
Autism spectrum disorders Epilepsy Latent class cluster analysis Phenotype |
Index. décimale : |
PER Périodiques |
Résumé : |
Epilepsy co-occurs frequently in autism spectrum disorders (ASD). Understanding this co-occurrence requires a better understanding of the ASD-epilepsy phenotype (or phenotypes). To address this, we conducted latent class cluster analysis (LCCA) on an ASD dataset (N = 577) which included 64 individuals with epilepsy. We identified a 5-cluster solution with one cluster showing a high rate of epilepsy (29%), earlier age at first recognition, and high rates of repetitive object use and unusual sensory interests. We also conducted LCCA on an ASD-epilepsy subset from the overall dataset (N = 64) which yielded three clusters, the largest of which had impairments in language and motor development; the remaining clusters, while not as developmentally impaired were characterized by different levels of repetitive and sensory behaviors. |
En ligne : |
http://dx.doi.org/10.1007/s10803-011-1402-y |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178 |
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