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Auteur Jean GOLDING |
Documents disponibles écrits par cet auteur (11)



Children's Adjustment and Prosocial Behaviour in Step-, Single-parent, and Non-stepfamily Settings: Findings from a Community Study / Judy DUNN in Journal of Child Psychology and Psychiatry, 39-8 (November 1998)
[article]
Titre : Children's Adjustment and Prosocial Behaviour in Step-, Single-parent, and Non-stepfamily Settings: Findings from a Community Study Type de document : Texte imprimé et/ou numérique Auteurs : Judy DUNN, Auteur ; Kirby DEATER-DECKARD, Auteur ; Kevin PICKERING, Auteur ; Thomas G. O'CONNOR, Auteur ; Jean GOLDING, Auteur Année de publication : 1998 Article en page(s) : p.1083-1095 Langues : Anglais (eng) Mots-clés : Behaviour problems emotional disorder family structure parent-child relationships preschool children school children Index. décimale : PER Périodiques Résumé : The adjustment and prosocial behaviour of 4-year-old children and their older siblings growing up in step-parent or single-parent families, or with two biological parents, was investigated within a longitudinal community study, the Avon Longitudinal Study of Pregnancy and Childhood (ALSPAC). Mean differences in mothers' perception of adjustment were found for children in different family settings, with higher levels of problems and lower prosocial scores reported for those in single- and step-parent families than those in non-stepfamilies. Individual differences within each family setting were marked. With the exception of single parenthood, which remained a risk indicator for the 4-year-olds, the contribution of family type to differences in adjustment and prosocial behaviour largely disappeared when account was also taken of negativity in family relationships, maternal age, education level, depressive symptomatology, and history of previous live-in relationships, mothers' support networks, and the family's current financial and housing circumstances. Boys remained more at risk for adjustment difficulties than girls when this range of factors was taken into account. The limitations and implications of these findings on a community sample, a first step in a programme of research into family processes in children's adjustment, are discussed. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124
in Journal of Child Psychology and Psychiatry > 39-8 (November 1998) . - p.1083-1095[article] Children's Adjustment and Prosocial Behaviour in Step-, Single-parent, and Non-stepfamily Settings: Findings from a Community Study [Texte imprimé et/ou numérique] / Judy DUNN, Auteur ; Kirby DEATER-DECKARD, Auteur ; Kevin PICKERING, Auteur ; Thomas G. O'CONNOR, Auteur ; Jean GOLDING, Auteur . - 1998 . - p.1083-1095.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 39-8 (November 1998) . - p.1083-1095
Mots-clés : Behaviour problems emotional disorder family structure parent-child relationships preschool children school children Index. décimale : PER Périodiques Résumé : The adjustment and prosocial behaviour of 4-year-old children and their older siblings growing up in step-parent or single-parent families, or with two biological parents, was investigated within a longitudinal community study, the Avon Longitudinal Study of Pregnancy and Childhood (ALSPAC). Mean differences in mothers' perception of adjustment were found for children in different family settings, with higher levels of problems and lower prosocial scores reported for those in single- and step-parent families than those in non-stepfamilies. Individual differences within each family setting were marked. With the exception of single parenthood, which remained a risk indicator for the 4-year-olds, the contribution of family type to differences in adjustment and prosocial behaviour largely disappeared when account was also taken of negativity in family relationships, maternal age, education level, depressive symptomatology, and history of previous live-in relationships, mothers' support networks, and the family's current financial and housing circumstances. Boys remained more at risk for adjustment difficulties than girls when this range of factors was taken into account. The limitations and implications of these findings on a community sample, a first step in a programme of research into family processes in children's adjustment, are discussed. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124 Common variation contributes to the genetic architecture of social communication traits / Beate ST POURCAIN in Molecular Autism, (September 2013)
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[article]
Titre : Common variation contributes to the genetic architecture of social communication traits Type de document : Texte imprimé et/ou numérique Auteurs : Beate ST POURCAIN, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Wei ANG, Auteur ; Nicole WARRINGTON, Auteur ; Joseph GLESSNER, Auteur ; Kai WANG, Auteur ; Nicholas TIMPSON, Auteur ; David EVANS, Auteur ; John KEMP, Auteur ; Susan RING, Auteur ; Wendy MCARDLE, Auteur ; Jean GOLDING, Auteur ; Hakon HAKONARSON, Auteur ; Craig E. PENNELL, Auteur ; George SMITH, Auteur Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Social communication difficulties represent an autistic trait that is highly heritable and persistent during the course of development. However, little is known about the underlying genetic architecture of this phenotype. We performed a genome-wide association study on parent-reported social communication problems using items of the children's communication checklist (age 10 to 11 years) studying single and/or joint marker effects. Analyses were conducted in a large UK population-based birth cohort (Avon Longitudinal Study of Parents and their Children, ALSPAC, N = 5,584) and followed-up within a sample of children with comparable measures from Western Australia (RAINE, N = 1364). Two of our seven independent top signals (P-discovery 1.0E-05) were replicated (0.009 P-replication [less than or equal to]0.02) within RAINE and suggested evidence for association at 6p22.1 (rs9257616, meta-P = 2.5E-07) and 14q22.1 (rs2352908, meta-P = 1.1E-06). The signal at 6p22.1 was identified within the olfactory receptor gene cluster within the broader major histocompatibility complex (MHC) region. The strongest candidate locus within this genomic area was TRIM27. This gene encodes an ubiquitin E3 ligase, which is an interaction partner of methyl-CpG-binding domain (MBD) proteins, such as MBD3 and MBD4, and rare protein-coding mutations within MBD3 and MBD4 have been linked to autism. The signal at 14q22.1 was found within a gene-poor region.Single-variant findings were complemented by estimations of the narrow-sense heritability in ALSPAC suggesting that approximately a fifth of the phenotypic variance in social communication traits is accounted for by joint additive effects of genotyped single nucleotide polymorphisms throughout the genome (h2(SE) = 0.18(0.066), P = 0.0027). Overall, our study provides both joint and single-SNP-based evidence for the contribution of common polymorphisms to variation in social communication phenotypes. En ligne : http://dx.doi.org/10.1186/2040-2392-4-34 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=227
in Molecular Autism > (September 2013)[article] Common variation contributes to the genetic architecture of social communication traits [Texte imprimé et/ou numérique] / Beate ST POURCAIN, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Wei ANG, Auteur ; Nicole WARRINGTON, Auteur ; Joseph GLESSNER, Auteur ; Kai WANG, Auteur ; Nicholas TIMPSON, Auteur ; David EVANS, Auteur ; John KEMP, Auteur ; Susan RING, Auteur ; Wendy MCARDLE, Auteur ; Jean GOLDING, Auteur ; Hakon HAKONARSON, Auteur ; Craig E. PENNELL, Auteur ; George SMITH, Auteur.
Langues : Anglais (eng)
in Molecular Autism > (September 2013)
Index. décimale : PER Périodiques Résumé : Social communication difficulties represent an autistic trait that is highly heritable and persistent during the course of development. However, little is known about the underlying genetic architecture of this phenotype. We performed a genome-wide association study on parent-reported social communication problems using items of the children's communication checklist (age 10 to 11 years) studying single and/or joint marker effects. Analyses were conducted in a large UK population-based birth cohort (Avon Longitudinal Study of Parents and their Children, ALSPAC, N = 5,584) and followed-up within a sample of children with comparable measures from Western Australia (RAINE, N = 1364). Two of our seven independent top signals (P-discovery 1.0E-05) were replicated (0.009 P-replication [less than or equal to]0.02) within RAINE and suggested evidence for association at 6p22.1 (rs9257616, meta-P = 2.5E-07) and 14q22.1 (rs2352908, meta-P = 1.1E-06). The signal at 6p22.1 was identified within the olfactory receptor gene cluster within the broader major histocompatibility complex (MHC) region. The strongest candidate locus within this genomic area was TRIM27. This gene encodes an ubiquitin E3 ligase, which is an interaction partner of methyl-CpG-binding domain (MBD) proteins, such as MBD3 and MBD4, and rare protein-coding mutations within MBD3 and MBD4 have been linked to autism. The signal at 14q22.1 was found within a gene-poor region.Single-variant findings were complemented by estimations of the narrow-sense heritability in ALSPAC suggesting that approximately a fifth of the phenotypic variance in social communication traits is accounted for by joint additive effects of genotyped single nucleotide polymorphisms throughout the genome (h2(SE) = 0.18(0.066), P = 0.0027). Overall, our study provides both joint and single-SNP-based evidence for the contribution of common polymorphisms to variation in social communication phenotypes. En ligne : http://dx.doi.org/10.1186/2040-2392-4-34 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=227 Gendered play behaviours in autistic and non-autistic children: A population-based cohort study / Laura HULL in Autism, 27-5 (July 2023)
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[article]
Titre : Gendered play behaviours in autistic and non-autistic children: A population-based cohort study Type de document : Texte imprimé et/ou numérique Auteurs : Laura HULL, Auteur ; Hein HEUVELMAN, Auteur ; Jean GOLDING, Auteur ; William MANDY, Auteur ; Dheeraj RAI, Auteur Article en page(s) : p.1449-1460 Langues : Anglais (eng) Mots-clés : development;gender;play;sex Index. décimale : PER Périodiques Résumé : Gender-typical play is observed throughout childhood for non-autistic children. However, there has been limited research into the gender typicality of autistic children?s play compared to that of non-autistic children. In a longitudinal population-based cohort, we compared gendered play behaviours in autistic and non-autistic children using standardised parent-report (30, 42 and 57?months) and child-report (8?years) data (N?=?11,251). We observed no difference in gendered play behaviours between girls with or without autism at any time point. Autistic and non-autistic boys did not differ in the gender typicality of their play when aged 30?months, but the play of autistic boys appeared less masculine than that of non-autistic boys (??=??1.1, 95% confidence interval?=??2.1 to ?0.2; and ??=??2.6, 95% confidence interval?=??4.7 to ?0.5) at 42 and 57?months. Autistic boys also self-reported less masculine play behaviours than non-autistic boys at 8?years of age (??=??3.4, 95% confidence interval?=??6.6 to ?0.2). We found that autistic boys' play was less gender typical than that of non-autistic boys in middle and later childhood. Our findings highlight the importance of examining gendered play behaviours in a developmental context and have relevance for understanding the development of gender identity in autism. Lay abstract Non-autistic children tend to show gendered patterns of play behaviours - boys are more likely to play with "masculine" toys, and girls are more likely to play with "feminine" toys. However, little is known about whether autistic children follow these patterns as well. We looked at the masculinity and femininity of autistic and non-autistic children?s play behaviours at multiple time points. Parents reported their children?s play behaviours at ages 30, 42 and 57?months, and children reported their own play behaviours at 8?years old. We found no difference between autistic and non-autistic girls, who both showed more feminine play behaviours as they got older. Autistic boys' play behaviours were reported as less masculine than non-autistic boys at 42 and 57?months, and at 8?years old. We also found that non-autistic boys' play tended to become more masculine as they got older, but this was not the case for autistic boys. Our findings suggest that differences in autistic and non-autistic boys' play behaviours may develop at around 42?months old. En ligne : http://dx.doi.org/10.1177/13623613221139373 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=507
in Autism > 27-5 (July 2023) . - p.1449-1460[article] Gendered play behaviours in autistic and non-autistic children: A population-based cohort study [Texte imprimé et/ou numérique] / Laura HULL, Auteur ; Hein HEUVELMAN, Auteur ; Jean GOLDING, Auteur ; William MANDY, Auteur ; Dheeraj RAI, Auteur . - p.1449-1460.
Langues : Anglais (eng)
in Autism > 27-5 (July 2023) . - p.1449-1460
Mots-clés : development;gender;play;sex Index. décimale : PER Périodiques Résumé : Gender-typical play is observed throughout childhood for non-autistic children. However, there has been limited research into the gender typicality of autistic children?s play compared to that of non-autistic children. In a longitudinal population-based cohort, we compared gendered play behaviours in autistic and non-autistic children using standardised parent-report (30, 42 and 57?months) and child-report (8?years) data (N?=?11,251). We observed no difference in gendered play behaviours between girls with or without autism at any time point. Autistic and non-autistic boys did not differ in the gender typicality of their play when aged 30?months, but the play of autistic boys appeared less masculine than that of non-autistic boys (??=??1.1, 95% confidence interval?=??2.1 to ?0.2; and ??=??2.6, 95% confidence interval?=??4.7 to ?0.5) at 42 and 57?months. Autistic boys also self-reported less masculine play behaviours than non-autistic boys at 8?years of age (??=??3.4, 95% confidence interval?=??6.6 to ?0.2). We found that autistic boys' play was less gender typical than that of non-autistic boys in middle and later childhood. Our findings highlight the importance of examining gendered play behaviours in a developmental context and have relevance for understanding the development of gender identity in autism. Lay abstract Non-autistic children tend to show gendered patterns of play behaviours - boys are more likely to play with "masculine" toys, and girls are more likely to play with "feminine" toys. However, little is known about whether autistic children follow these patterns as well. We looked at the masculinity and femininity of autistic and non-autistic children?s play behaviours at multiple time points. Parents reported their children?s play behaviours at ages 30, 42 and 57?months, and children reported their own play behaviours at 8?years old. We found no difference between autistic and non-autistic girls, who both showed more feminine play behaviours as they got older. Autistic boys' play behaviours were reported as less masculine than non-autistic boys at 42 and 57?months, and at 8?years old. We also found that non-autistic boys' play tended to become more masculine as they got older, but this was not the case for autistic boys. Our findings suggest that differences in autistic and non-autistic boys' play behaviours may develop at around 42?months old. En ligne : http://dx.doi.org/10.1177/13623613221139373 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=507 Identification of children with the same level of impairment as children on the autistic spectrum, and analysis of their service use / Ginny RUSSELL in Journal of Child Psychology and Psychiatry, 51-6 (June 2010)
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Titre : Identification of children with the same level of impairment as children on the autistic spectrum, and analysis of their service use Type de document : Texte imprimé et/ou numérique Auteurs : Ginny RUSSELL, Auteur ; Tamsin FORD, Auteur ; Jean GOLDING, Auteur ; Colin STEER, Auteur Année de publication : 2010 Article en page(s) : p.643-651 Langues : Anglais (eng) Mots-clés : Autism pervasive-developmental-disorders Asperger's-syndrome epidemiology prevalence child-mental-health Index. décimale : PER Périodiques Résumé : Background: Data from epidemiology have consistently highlighted a disparity between the true prevalence of childhood psychiatric disorders and their recognition as defined by receiving a clinical diagnosis. Few studies have looked specifically at the level of unidentified autistic spectrum disorder (ASD) in the population.
Method: Logistic regression was used to determine the behavioural traits associated with receiving a diagnosis of ASD using data from the Avon Longitudinal Study of Parents and Children (ALSPAC). A composite score was derived to measure levels of autistic traits; undiagnosed children with scores matching those diagnosed with ASD were identified. Levels of educational provision beyond that provided by standard schooling were examined.
Results: Fifty-five percent of children with autistic traits at the same levels as those who had an autism diagnosis had not been identified as needing extra support from education or specialised health services. Of those who were identified as having special needs, 37.5% had been formally diagnosed with an ASD. For children with impairment at the same level as that associated with Asperger's syndrome, 57% had no special provision at school, and were not accessing specialised health services. Twenty-six percent of those who did have special provision at school had an ASD diagnosis.
Conclusions: The results suggest that there may be a substantial proportion of children on the autistic spectrum who are never identified by services.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02233.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=101
in Journal of Child Psychology and Psychiatry > 51-6 (June 2010) . - p.643-651[article] Identification of children with the same level of impairment as children on the autistic spectrum, and analysis of their service use [Texte imprimé et/ou numérique] / Ginny RUSSELL, Auteur ; Tamsin FORD, Auteur ; Jean GOLDING, Auteur ; Colin STEER, Auteur . - 2010 . - p.643-651.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 51-6 (June 2010) . - p.643-651
Mots-clés : Autism pervasive-developmental-disorders Asperger's-syndrome epidemiology prevalence child-mental-health Index. décimale : PER Périodiques Résumé : Background: Data from epidemiology have consistently highlighted a disparity between the true prevalence of childhood psychiatric disorders and their recognition as defined by receiving a clinical diagnosis. Few studies have looked specifically at the level of unidentified autistic spectrum disorder (ASD) in the population.
Method: Logistic regression was used to determine the behavioural traits associated with receiving a diagnosis of ASD using data from the Avon Longitudinal Study of Parents and Children (ALSPAC). A composite score was derived to measure levels of autistic traits; undiagnosed children with scores matching those diagnosed with ASD were identified. Levels of educational provision beyond that provided by standard schooling were examined.
Results: Fifty-five percent of children with autistic traits at the same levels as those who had an autism diagnosis had not been identified as needing extra support from education or specialised health services. Of those who were identified as having special needs, 37.5% had been formally diagnosed with an ASD. For children with impairment at the same level as that associated with Asperger's syndrome, 57% had no special provision at school, and were not accessing specialised health services. Twenty-six percent of those who did have special provision at school had an ASD diagnosis.
Conclusions: The results suggest that there may be a substantial proportion of children on the autistic spectrum who are never identified by services.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02233.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=101 Maternal childhood abuse and offspring adjustment over time / Stephan COLLISHAW in Development and Psychopathology, 19-2 (Spring 2007)
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Titre : Maternal childhood abuse and offspring adjustment over time Type de document : Texte imprimé et/ou numérique Auteurs : Stephan COLLISHAW, Auteur ; Thomas G. O'CONNOR, Auteur ; Judy DUNN, Auteur ; Jean GOLDING, Auteur Année de publication : 2007 Article en page(s) : p.367-383 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : This study addressed the basis for the intergenerational transmission of psychosocial risk associated with maternal childhood abuse in relation to offspring adjustment. The study tested how far group differences in individual change in adjustment over time were explained by differences in exposure to specific environmental risk experiences. Data are drawn from the Avon Longitudinal Study of Parents and Children. Information on mothers' own experience of childhood abuse, offspring adjustment at ages 4 and 7 years, and hypothesized mediators was available for 5,619 families. A residuals scores analysis was used to track children's adjustment over time. Maternal childhood abuse was associated with poorer behavioral trajectories between ages 4 and 7 years. Children of abused mothers were more likely to experience a range of negative life events between ages 4 and 7 years, including changes in family composition, separations from parents, “shocks and frights” and physical assaults. Interim life events, together with antecedent psychosocial risk (maternal antenatal affective symptoms, age 4 parental hostility, age 4 family type) fully mediated the association between maternal childhood abuse and offspring prognosis. En ligne : http://dx.doi.org/10.1017/s0954579407070186 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=104
in Development and Psychopathology > 19-2 (Spring 2007) . - p.367-383[article] Maternal childhood abuse and offspring adjustment over time [Texte imprimé et/ou numérique] / Stephan COLLISHAW, Auteur ; Thomas G. O'CONNOR, Auteur ; Judy DUNN, Auteur ; Jean GOLDING, Auteur . - 2007 . - p.367-383.
Langues : Anglais (eng)
in Development and Psychopathology > 19-2 (Spring 2007) . - p.367-383
Index. décimale : PER Périodiques Résumé : This study addressed the basis for the intergenerational transmission of psychosocial risk associated with maternal childhood abuse in relation to offspring adjustment. The study tested how far group differences in individual change in adjustment over time were explained by differences in exposure to specific environmental risk experiences. Data are drawn from the Avon Longitudinal Study of Parents and Children. Information on mothers' own experience of childhood abuse, offspring adjustment at ages 4 and 7 years, and hypothesized mediators was available for 5,619 families. A residuals scores analysis was used to track children's adjustment over time. Maternal childhood abuse was associated with poorer behavioral trajectories between ages 4 and 7 years. Children of abused mothers were more likely to experience a range of negative life events between ages 4 and 7 years, including changes in family composition, separations from parents, “shocks and frights” and physical assaults. Interim life events, together with antecedent psychosocial risk (maternal antenatal affective symptoms, age 4 parental hostility, age 4 family type) fully mediated the association between maternal childhood abuse and offspring prognosis. En ligne : http://dx.doi.org/10.1017/s0954579407070186 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=104 Maternal vitamin D during pregnancy and offspring autism and autism-associated traits: a prospective cohort study / Paul MADLEY-DOWD in Molecular Autism, 13 (2022)
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PermalinkParental Divorce and Adjustment in Adulthood: Findings from a Community Sample / Thomas G. O'CONNOR in Journal of Child Psychology and Psychiatry, 40-5 (July 1999)
PermalinkSiblings, Parents, and Partners: Family Relationships within a Longitudinal Community Study / Judy DUNN in Journal of Child Psychology and Psychiatry, 40-7 (October 1999)
PermalinkSocial and behavioural outcomes in children diagnosed with autism spectrum disorders: a longitudinal cohort study / Ginny RUSSELL in Journal of Child Psychology and Psychiatry, 53-7 (July 2012)
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PermalinkVariability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence / Beate ST POURCAIN in Molecular Autism, (February 2014)
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PermalinkWhich children receive grandparental care and what effect does it have? / Emma FERGUSSON in Journal of Child Psychology and Psychiatry, 49-2 (February 2008)
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