Dépouillements

The embryogenesis of trypan-blue induced spina bifida aperta and short tail in the rat / R. G. LENDON in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.3-10 Titre : The embryogenesis of trypan-blue induced spina bifida aperta and short tail in the rat Type de document : Texte imprimé et/ou numérique Auteurs : R. G. LENDON, Auteur Année de publication : 1975 Article en page(s) : p.3-10 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The study of litters from 140 Wistar-derived rats injected with trypan blue during gestation leads to conclusion that a myelocele can result from faulty closure of the neural plate and that this is accompanied in many cases by blebs in the paraxial mesoderm. Haematomata usually underlie the open neural plate at an early stage and they form by extravasation of blood from the dorsal aortae into the blebs. Local ventral deflection of the notochord beneath a myelocele probably results from delayed separation of the notochord from the hindgut. Complete failure of separation and abnormality induced in the tail-bud could result in sacral agenesis and/or a short tail. All these malformations may result from varying severity of the action of the trypan blue at different developmental stages. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449 [article] The embryogenesis of trypan-blue induced spina bifida aperta and short tail in the rat [Texte imprimé et/ou numérique] / R. G. LENDON, Auteur . - 1975 . - p.3-10. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.3-10 Index. décimale : PER Périodiques Résumé : The study of litters from 140 Wistar-derived rats injected with trypan blue during gestation leads to conclusion that a myelocele can result from faulty closure of the neural plate and that this is accompanied in many cases by blebs in the paraxial mesoderm. Haematomata usually underlie the open neural plate at an early stage and they form by extravasation of blood from the dorsal aortae into the blebs. Local ventral deflection of the notochord beneath a myelocele probably results from delayed separation of the notochord from the hindgut. Complete failure of separation and abnormality induced in the tail-bud could result in sacral agenesis and/or a short tail. All these malformations may result from varying severity of the action of the trypan blue at different developmental stages. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449

Physical and biochemical characteristics of the human dysraphic spinal cord / A. J. BARSON in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.11-19 Titre : Physical and biochemical characteristics of the human dysraphic spinal cord Type de document : Texte imprimé et/ou numérique Auteurs : A. J. BARSON, Auteur ; J. SANDS, Auteur Année de publication : 1975 Article en page(s) : p.11-19 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The spinal cords were removed from 29 infants between 17 and 46 weeks gestation, all with various forms of spinal dysraphia. The spinal cords were assessed for weight, length, thickness, size and number of cells, and myelination, and then were compared with 86 control spinal cords. The strongest characteristic of the dysraphic cords was a reduced degree of myelination. Cell size and number generally were appropriate for the weight of the cords. There was a tendency for cord weight, length and thickness to be reduced, though in part this was a reflection of poor over-all bodily growth. In a small group of infants these measurements were increased in comparison with the controls. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449 [article] Physical and biochemical characteristics of the human dysraphic spinal cord [Texte imprimé et/ou numérique] / A. J. BARSON, Auteur ; J. SANDS, Auteur . - 1975 . - p.11-19. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.11-19 Index. décimale : PER Périodiques Résumé : The spinal cords were removed from 29 infants between 17 and 46 weeks gestation, all with various forms of spinal dysraphia. The spinal cords were assessed for weight, length, thickness, size and number of cells, and myelination, and then were compared with 86 control spinal cords. The strongest characteristic of the dysraphic cords was a reduced degree of myelination. Cell size and number generally were appropriate for the weight of the cords. There was a tendency for cord weight, length and thickness to be reduced, though in part this was a reflection of poor over-all bodily growth. In a small group of infants these measurements were increased in comparison with the controls. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449

A quantitative study of the cell population of the cerebellum in children with myelomeningocele / John L. EMERY in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.20-25 Titre : A quantitative study of the cell population of the cerebellum in children with myelomeningocele Type de document : Texte imprimé et/ou numérique Auteurs : John L. EMERY, Auteur ; Derek R. GADSDON, Auteur Année de publication : 1975 Article en page(s) : p.20-25 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : A quantitative assessment has been carried out on the cell populations and DNA content of the cells in the internal granular layer of the central lobes of the cerebellum from 100 children with myelomeningocele and from 120 normal controls. The method used was a computerised analysis of a television image of the neurones in standardised sections. The cell and DNA complement of the declive and central lobe are only slightly reduced in the cases of myelomeningocele, but there is frequently cellular and DNA loss throughout the pyramid and uvula to the nodule. These findings suggest that the central lobes of the cerebellum are probably genetically normal but have irregular degeneration and arrest of growth, probably as an effect of pressure at the foramen magnum. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449 [article] A quantitative study of the cell population of the cerebellum in children with myelomeningocele [Texte imprimé et/ou numérique] / John L. EMERY, Auteur ; Derek R. GADSDON, Auteur . - 1975 . - p.20-25. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.20-25 Index. décimale : PER Périodiques Résumé : A quantitative assessment has been carried out on the cell populations and DNA content of the cells in the internal granular layer of the central lobes of the cerebellum from 100 children with myelomeningocele and from 120 normal controls. The method used was a computerised analysis of a television image of the neurones in standardised sections. The cell and DNA complement of the declive and central lobe are only slightly reduced in the cases of myelomeningocele, but there is frequently cellular and DNA loss throughout the pyramid and uvula to the nodule. These findings suggest that the central lobes of the cerebellum are probably genetically normal but have irregular degeneration and arrest of growth, probably as an effect of pressure at the foramen magnum. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449

The tectum and the aqueduct of Sylvius in hydrocephalus unassociated with myelomeningocele / Ian SHELLSHEAR in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.26-34 Titre : The tectum and the aqueduct of Sylvius in hydrocephalus unassociated with myelomeningocele Type de document : Texte imprimé et/ou numérique Auteurs : Ian SHELLSHEAR, Auteur ; John L. EMERY, Auteur Année de publication : 1975 Article en page(s) : p.26-34 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The brains of 30 children with hydrocephalus (but not myelomeningocele) were examined. It was found that secondary pressures on the tectum and aqueduct resulting from the hydrocephalus were responsible for further obstruction at this level in 15 of the 30 children and that they contributed to axial distortion in another 11 children. Occlusion of the aqueduct occurred as a result either of these external pressures or of internal gliosis. These events form a self-sustaining cycle which, if broken early, may lead to a more satisfactory control of the hydrocephalus. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] The tectum and the aqueduct of Sylvius in hydrocephalus unassociated with myelomeningocele [Texte imprimé et/ou numérique] / Ian SHELLSHEAR, Auteur ; John L. EMERY, Auteur . - 1975 . - p.26-34. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.26-34 Index. décimale : PER Périodiques Résumé : The brains of 30 children with hydrocephalus (but not myelomeningocele) were examined. It was found that secondary pressures on the tectum and aqueduct resulting from the hydrocephalus were responsible for further obstruction at this level in 15 of the 30 children and that they contributed to axial distortion in another 11 children. Occlusion of the aqueduct occurred as a result either of these external pressures or of internal gliosis. These events form a self-sustaining cycle which, if broken early, may lead to a more satisfactory control of the hydrocephalus. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Dandy-Walker syndrome associated with congenital heart defects: report of three cases / T. T. HUONG in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.35-41 Titre : Dandy-Walker syndrome associated with congenital heart defects: report of three cases Type de document : Texte imprimé et/ou numérique Auteurs : T. T. HUONG, Auteur ; E. GOLDBATT, Auteur ; D.A. SIMPSON, Auteur Année de publication : 1975 Article en page(s) : p.35-41 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Three cases of Dandy-Walker syndrome associated with congenital heart defects are reported, and their management is described. The various theories concerning the aetiology of the Dandy-Walker syndrome are discussed and it is suggested that the theory of primary developmental atresia of the foramina of Magendie and Luschka is still acceptable. If the child with Dandy-Walker syndrome requires treatment by extracranial CSF drainage it is proposed that a ventriculo-peritoneal shunt is preferable when there is any suspicion of cardiac anomaly. The proximal catheter should be placed in the posterior fossa cyst (dilated fourth ventricle) rather than in the lateral ventricle. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Dandy-Walker syndrome associated with congenital heart defects: report of three cases [Texte imprimé et/ou numérique] / T. T. HUONG, Auteur ; E. GOLDBATT, Auteur ; D.A. SIMPSON, Auteur . - 1975 . - p.35-41. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.35-41 Index. décimale : PER Périodiques Résumé : Three cases of Dandy-Walker syndrome associated with congenital heart defects are reported, and their management is described. The various theories concerning the aetiology of the Dandy-Walker syndrome are discussed and it is suggested that the theory of primary developmental atresia of the foramina of Magendie and Luschka is still acceptable. If the child with Dandy-Walker syndrome requires treatment by extracranial CSF drainage it is proposed that a ventriculo-peritoneal shunt is preferable when there is any suspicion of cardiac anomaly. The proximal catheter should be placed in the posterior fossa cyst (dilated fourth ventricle) rather than in the lateral ventricle. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Changes in regional blood-flow and water content of brain and spinal cord in acute and chronic experimental hydrocephalus / Gerald M. HOCHWALD in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.42-50 Titre : Changes in regional blood-flow and water content of brain and spinal cord in acute and chronic experimental hydrocephalus Type de document : Texte imprimé et/ou numérique Auteurs : Gerald M. HOCHWALD, Auteur ; R. D. BOAL, Auteur ; A. E. MARLIN, Auteur ; A. J. KUMAR, Auteur Année de publication : 1975 Article en page(s) : p.42-50 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The effects of kaolin-induced hydrocephalus on regional blood-flow and water content of cat brain and spinal cord were measured. The role of the central canal of the spinal cord as an alternative pathway for cerebrospinal fluid in experimental hydrocephalus was also studied by positive contrast ventriculography. In comparison with normal cats, blood-flow in the cerebrum, cerebellum and brain stem of cats with acute hydrocephalus was reduced by more than 20 per cent: in those with chronic hydrocephalus it was reduced by only 12 per cent. There was an absolute increase of 1-5 per cent in water content of the brain in cats with acute hydrocephalus. Water content in the spinal cord was increased by 6 per cent in cats with acute hydrocephalus and by 8 per cent in those with chronic hydrocephalus. When the increased water-content was taken into account, hydrocephalus caused no significant change in blood-flow in the cervical, thoracic or lumbar spinal cord. Contrast material perfused through the ventricles of hydrocephalic cats flowed directly into the enlarged central canal of the spinal cord. Kaolin-induced arachnoiditis completely obstructed communication between the ventricles and the cranial subarachnoid space. The contrast material in the central canal communicated both with the cavities extending into the dorsal columns and with the spinal subarachnoid space. When kaolin was injected directly into the spinal subarachnoid space there was an increase in spinal water-content, without an enlarged central canal. These results suggest that in addition to kaolin-induced arachnoiditis, increased intraluminal pressure is necessary to enlarge the central canal. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Changes in regional blood-flow and water content of brain and spinal cord in acute and chronic experimental hydrocephalus [Texte imprimé et/ou numérique] / Gerald M. HOCHWALD, Auteur ; R. D. BOAL, Auteur ; A. E. MARLIN, Auteur ; A. J. KUMAR, Auteur . - 1975 . - p.42-50. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.42-50 Index. décimale : PER Périodiques Résumé : The effects of kaolin-induced hydrocephalus on regional blood-flow and water content of cat brain and spinal cord were measured. The role of the central canal of the spinal cord as an alternative pathway for cerebrospinal fluid in experimental hydrocephalus was also studied by positive contrast ventriculography. In comparison with normal cats, blood-flow in the cerebrum, cerebellum and brain stem of cats with acute hydrocephalus was reduced by more than 20 per cent: in those with chronic hydrocephalus it was reduced by only 12 per cent. There was an absolute increase of 1-5 per cent in water content of the brain in cats with acute hydrocephalus. Water content in the spinal cord was increased by 6 per cent in cats with acute hydrocephalus and by 8 per cent in those with chronic hydrocephalus. When the increased water-content was taken into account, hydrocephalus caused no significant change in blood-flow in the cervical, thoracic or lumbar spinal cord. Contrast material perfused through the ventricles of hydrocephalic cats flowed directly into the enlarged central canal of the spinal cord. Kaolin-induced arachnoiditis completely obstructed communication between the ventricles and the cranial subarachnoid space. The contrast material in the central canal communicated both with the cavities extending into the dorsal columns and with the spinal subarachnoid space. When kaolin was injected directly into the spinal subarachnoid space there was an increase in spinal water-content, without an enlarged central canal. These results suggest that in addition to kaolin-induced arachnoiditis, increased intraluminal pressure is necessary to enlarge the central canal. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Cerebrospinal fluid dynamics in megalencephaly / Michael J. BRESNAN in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.51-57 Titre : Cerebrospinal fluid dynamics in megalencephaly Type de document : Texte imprimé et/ou numérique Auteurs : Michael J. BRESNAN, Auteur ; Antonio V. LORENZO, Auteur Année de publication : 1975 Article en page(s) : p.51-57 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Macrocephaly is one of the signs most commonly used in the diagnosis of hydrocephalus. Two children are reported who presented with macrocephaly. The results of neurological examination were normal apart from delay in mental development. Head circumferences were above the 98th percentile. Air studies showed mildly dilated ventricles with no obstruction, and ventriculolumbar perfusions indicated normal rates of cerebrospinal fluid formation and absorption. At seven years of age the children were mildly mentally retarded, with head circumferences above the 98th percentile. In the girl the ventricles were still mildly dilated but in the boy they were normal. It is concluded that the macrocephaly in these two children was the result of progressive megalencephaly and not of abnormal ventricular enlargement (hydrocephalus). Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Cerebrospinal fluid dynamics in megalencephaly [Texte imprimé et/ou numérique] / Michael J. BRESNAN, Auteur ; Antonio V. LORENZO, Auteur . - 1975 . - p.51-57. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.51-57 Index. décimale : PER Périodiques Résumé : Macrocephaly is one of the signs most commonly used in the diagnosis of hydrocephalus. Two children are reported who presented with macrocephaly. The results of neurological examination were normal apart from delay in mental development. Head circumferences were above the 98th percentile. Air studies showed mildly dilated ventricles with no obstruction, and ventriculolumbar perfusions indicated normal rates of cerebrospinal fluid formation and absorption. At seven years of age the children were mildly mentally retarded, with head circumferences above the 98th percentile. In the girl the ventricles were still mildly dilated but in the boy they were normal. It is concluded that the macrocephaly in these two children was the result of progressive megalencephaly and not of abnormal ventricular enlargement (hydrocephalus). Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Lacunar skull deformity related to intelligence in children with myelomeningocele and hydrocephalus / A. P. LONTON in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.58-64 Titre : Lacunar skull deformity related to intelligence in children with myelomeningocele and hydrocephalus Type de document : Texte imprimé et/ou numérique Auteurs : A. P. LONTON, Auteur ; N. A. BARRINGTON, Auteur ; John LORBER, Auteur Année de publication : 1975 Article en page(s) : p.58-64 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : It has been suggested that the presence of lacunar skull deformity in infants with myelomeningocele and hydrocephalus is indicative of later lowered intelligence and therefore is a useful criterion in early selection for treatment. In the present study, retrospective investigations were made of the clinical records and skull X-rays of 169 surviving children who had been admitted immediately after birth with myelomeningocele and hydrocephalus to the Children's Hospital, Sheffield. Adequate X-rays were available for 131 of the children, of whom 97 per cent exhibited some degree of lacunar skull deformity. At five years of age or older, the 131 children were tested on the Wechsler Intelligence Scale for Children. The differences in mean IQ between the various degrees of severity were not large, and it was found that 82 per cent of children with the most severe degree of lacunar skull deformity had IQs above 70. These findings do not support the use of lacunar skull deformity as an important measure in selection for treatment of children with myelomeningocele and hydrocephalus. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Lacunar skull deformity related to intelligence in children with myelomeningocele and hydrocephalus [Texte imprimé et/ou numérique] / A. P. LONTON, Auteur ; N. A. BARRINGTON, Auteur ; John LORBER, Auteur . - 1975 . - p.58-64. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.58-64 Index. décimale : PER Périodiques Résumé : It has been suggested that the presence of lacunar skull deformity in infants with myelomeningocele and hydrocephalus is indicative of later lowered intelligence and therefore is a useful criterion in early selection for treatment. In the present study, retrospective investigations were made of the clinical records and skull X-rays of 169 surviving children who had been admitted immediately after birth with myelomeningocele and hydrocephalus to the Children's Hospital, Sheffield. Adequate X-rays were available for 131 of the children, of whom 97 per cent exhibited some degree of lacunar skull deformity. At five years of age or older, the 131 children were tested on the Wechsler Intelligence Scale for Children. The differences in mean IQ between the various degrees of severity were not large, and it was found that 82 per cent of children with the most severe degree of lacunar skull deformity had IQs above 70. These findings do not support the use of lacunar skull deformity as an important measure in selection for treatment of children with myelomeningocele and hydrocephalus. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Some factors relating to intelligence in treated children with spina bifida cystica / Gillian M. HUNT in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.65-70 Titre : Some factors relating to intelligence in treated children with spina bifida cystica Type de document : Texte imprimé et/ou numérique Auteurs : Gillian M. HUNT, Auteur ; Alec E. HOLMES, Auteur Année de publication : 1975 Article en page(s) : p.65-70 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The 83 survivors of a consecutive series of children with spina bifida cystica, born between 1963 and 1971 and treated non-selectively since birth, were assessed by intelligence and developmental testing. In nine of the children who had not required shunts the distribution of intelligence was within the normal range. The need for a shunt was significantly related to the presence of craniolacunae and to the sensory level of the lesion recorded at birth. Seven of the 74 shunt-treated children had suffered ventriculitis, meningitis or septicaemia, and their intelligence was significantly worse than the others. In the 67 shunt-treated children who had not suffered infection, intelligence was significantly related to the thickness of the pallium when the shunt was inserted during the first four weeks of life, and to the sensory level of the lesion recorded at birth. Intelligence was not related to the function of the shunt at time of assessment, to the number of revisions of the shunt, or to the rate of increase in head size during the first four weeks of life. It is concluded that the best indication of later intelligence can be gained at birth from the thickness of the pallium and the sensory level of the lesion. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Some factors relating to intelligence in treated children with spina bifida cystica [Texte imprimé et/ou numérique] / Gillian M. HUNT, Auteur ; Alec E. HOLMES, Auteur . - 1975 . - p.65-70. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.65-70 Index. décimale : PER Périodiques Résumé : The 83 survivors of a consecutive series of children with spina bifida cystica, born between 1963 and 1971 and treated non-selectively since birth, were assessed by intelligence and developmental testing. In nine of the children who had not required shunts the distribution of intelligence was within the normal range. The need for a shunt was significantly related to the presence of craniolacunae and to the sensory level of the lesion recorded at birth. Seven of the 74 shunt-treated children had suffered ventriculitis, meningitis or septicaemia, and their intelligence was significantly worse than the others. In the 67 shunt-treated children who had not suffered infection, intelligence was significantly related to the thickness of the pallium when the shunt was inserted during the first four weeks of life, and to the sensory level of the lesion recorded at birth. Intelligence was not related to the function of the shunt at time of assessment, to the number of revisions of the shunt, or to the rate of increase in head size during the first four weeks of life. It is concluded that the best indication of later intelligence can be gained at birth from the thickness of the pallium and the sensory level of the lesion. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Avoidance of shunt dependency in hydrocephalus / Fred J. EPSTEIN in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.71-77 Titre : Avoidance of shunt dependency in hydrocephalus Type de document : Texte imprimé et/ou numérique Auteurs : Fred J. EPSTEIN, Auteur ; Gerald M. HOCHWALD, Auteur ; Alvin WALD, Auteur ; Joseph RANSOHOFF, Auteur Année de publication : 1975 Article en page(s) : p.71-77 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : An approach to the treatment of neonatal hydrocephalus is proposed which is intended to reduce or eliminate shunt dependency by increasing the effectiveness of remaining pathways of absorption of cerebrospinal fluid. In suitable cases, intermittent cranial compression by means of an elastic bandage or a helmet with an inflatable inner-lining may be effective. Hydrocephalus was arrested in nine of 14 children treated with this method, eight of whom have developed normally. When cranial compression is contra-indicated or not successful, the preferred method of treatment is an 'on-off' type of valve which is used intermittently to drain a fixed volume of cerebrospinal fluid. Of 18 children who had such shunts inserted, 10 have become totally independent of their shunts and their hydrocephalus has become compensated. All are of normal intelligence. Subtemporal craniectomy was performed on seven shunt-dependent children with recurrent catheter obstruction. Four have been followed for six months and three for two years and in no case has there been further malfunction of the proximal catheter. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Avoidance of shunt dependency in hydrocephalus [Texte imprimé et/ou numérique] / Fred J. EPSTEIN, Auteur ; Gerald M. HOCHWALD, Auteur ; Alvin WALD, Auteur ; Joseph RANSOHOFF, Auteur . - 1975 . - p.71-77. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.71-77 Index. décimale : PER Périodiques Résumé : An approach to the treatment of neonatal hydrocephalus is proposed which is intended to reduce or eliminate shunt dependency by increasing the effectiveness of remaining pathways of absorption of cerebrospinal fluid. In suitable cases, intermittent cranial compression by means of an elastic bandage or a helmet with an inflatable inner-lining may be effective. Hydrocephalus was arrested in nine of 14 children treated with this method, eight of whom have developed normally. When cranial compression is contra-indicated or not successful, the preferred method of treatment is an 'on-off' type of valve which is used intermittently to drain a fixed volume of cerebrospinal fluid. Of 18 children who had such shunts inserted, 10 have become totally independent of their shunts and their hydrocephalus has become compensated. All are of normal intelligence. Subtemporal craniectomy was performed on seven shunt-dependent children with recurrent catheter obstruction. Four have been followed for six months and three for two years and in no case has there been further malfunction of the proximal catheter. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

The problems of design and implantation of shunt systems for the treatment of hydrocephalus / B. H. DAWSON in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.78-84 Titre : The problems of design and implantation of shunt systems for the treatment of hydrocephalus Type de document : Texte imprimé et/ou numérique Auteurs : B. H. DAWSON, Auteur ; E. DERVIN, Auteur ; O. B. HEYWOOD, Auteur Année de publication : 1975 Article en page(s) : p.78-84 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Engineers and surgeons concerned with the design and use of shunt systems for the treatment of hydrocephalus share the wish to avoid the implantation of defective devices and to improve existing shunt systems. This study considers the causes of shunt failure or malfunction and seeks to define the areas in which improvements are needed. An important factor in bringing about improvements is that surgeons communicate to designers and manufacturers their clinical observations of defective materials or performance in existing shunt systems. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] The problems of design and implantation of shunt systems for the treatment of hydrocephalus [Texte imprimé et/ou numérique] / B. H. DAWSON, Auteur ; E. DERVIN, Auteur ; O. B. HEYWOOD, Auteur . - 1975 . - p.78-84. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.78-84 Index. décimale : PER Périodiques Résumé : Engineers and surgeons concerned with the design and use of shunt systems for the treatment of hydrocephalus share the wish to avoid the implantation of defective devices and to improve existing shunt systems. This study considers the causes of shunt failure or malfunction and seeks to define the areas in which improvements are needed. An important factor in bringing about improvements is that surgeons communicate to designers and manufacturers their clinical observations of defective materials or performance in existing shunt systems. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

A study of the Indian valve for ventriculo-atrial shunts in the treatment of hydrocephalus / Gurmail SINGH in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.85-88 Titre : A study of the Indian valve for ventriculo-atrial shunts in the treatment of hydrocephalus Type de document : Texte imprimé et/ou numérique Auteurs : Gurmail SINGH, Auteur ; Michael ANTHONY, Auteur ; Luis Leon MARINO, Auteur ; Robert B. ZACHARY, Auteur Année de publication : 1975 Article en page(s) : p.85-88 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Because of the high costs of importing commercially-available shunts, a hand-made ventriculo-atrial shunt was devised in India for the treatment of hydrocephalus. Modifications have been made to the original design and these shunts are now being produced commercially at a fraction of the cost of other available shunts. Hydrodynamic testing indicates that they compare favourably with the other shunts at present in use Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] A study of the Indian valve for ventriculo-atrial shunts in the treatment of hydrocephalus [Texte imprimé et/ou numérique] / Gurmail SINGH, Auteur ; Michael ANTHONY, Auteur ; Luis Leon MARINO, Auteur ; Robert B. ZACHARY, Auteur . - 1975 . - p.85-88. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.85-88 Index. décimale : PER Périodiques Résumé : Because of the high costs of importing commercially-available shunts, a hand-made ventriculo-atrial shunt was devised in India for the treatment of hydrocephalus. Modifications have been made to the original design and these shunts are now being produced commercially at a fraction of the cost of other available shunts. Hydrodynamic testing indicates that they compare favourably with the other shunts at present in use Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Expanding ventricular shunts for hydrocephalus in infancy and childhood / Mary K. HAMMOCK in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.89-93 Titre : Expanding ventricular shunts for hydrocephalus in infancy and childhood Type de document : Texte imprimé et/ou numérique Auteurs : Mary K. HAMMOCK, Auteur ; Thomas H. MILHORAT, Auteur ; J. E. MCCLENATHAN, Auteur Année de publication : 1975 Article en page(s) : p.89-93 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Expanding, adult-length catheters to accommodate continuing somatic growth have been implanted in the course of shunts, either to the heart or peritoneum, in 12 hydrocephalic infants and young children. Three of four patients with direct cardiac shunts are doing well 22, 28 and 30 months following primary shunt operations, and five of eight patients with ventriculo-peritoneal shunts are progressing favourably four to 10 months after shunt placement. While no claims can be made for long-term benefits, the preliminary results of these procedures are encouraging. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Expanding ventricular shunts for hydrocephalus in infancy and childhood [Texte imprimé et/ou numérique] / Mary K. HAMMOCK, Auteur ; Thomas H. MILHORAT, Auteur ; J. E. MCCLENATHAN, Auteur . - 1975 . - p.89-93. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.89-93 Index. décimale : PER Périodiques Résumé : Expanding, adult-length catheters to accommodate continuing somatic growth have been implanted in the course of shunts, either to the heart or peritoneum, in 12 hydrocephalic infants and young children. Three of four patients with direct cardiac shunts are doing well 22, 28 and 30 months following primary shunt operations, and five of eight patients with ventriculo-peritoneal shunts are progressing favourably four to 10 months after shunt placement. While no claims can be made for long-term benefits, the preliminary results of these procedures are encouraging. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

The use of the valvogram for the detection of shunt blockage in hydrocephalic children / R. C. EVANS in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.94-98 Titre : The use of the valvogram for the detection of shunt blockage in hydrocephalic children Type de document : Texte imprimé et/ou numérique Auteurs : R. C. EVANS, Auteur ; THOMAS M. D., Auteur ; L. A. WILLIAMS, Auteur Année de publication : 1975 Article en page(s) : p.94-98 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Valvography is a simple, safe, rapid, easily interpreted technique for the investigation of possible blockage of the distal end of the shunt system containing a Spitz-Holter valve. Details are presented of 64 investigations in 46 children, 30 of which demonstrated distal obstruction of the shunt system. The unreliability of some physical signs is discussed. No serious complications were encountered and the procedure has proved to be a valuable addition to the practical management of shunt-dependent children. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] The use of the valvogram for the detection of shunt blockage in hydrocephalic children [Texte imprimé et/ou numérique] / R. C. EVANS, Auteur ; THOMAS M. D., Auteur ; L. A. WILLIAMS, Auteur . - 1975 . - p.94-98. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.94-98 Index. décimale : PER Périodiques Résumé : Valvography is a simple, safe, rapid, easily interpreted technique for the investigation of possible blockage of the distal end of the shunt system containing a Spitz-Holter valve. Details are presented of 64 investigations in 46 children, 30 of which demonstrated distal obstruction of the shunt system. The unreliability of some physical signs is discussed. No serious complications were encountered and the procedure has proved to be a valuable addition to the practical management of shunt-dependent children. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451

Antibiotic prophylaxis in shunt surgery / R. BAYSTON in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.99-103 Titre : Antibiotic prophylaxis in shunt surgery Type de document : Texte imprimé et/ou numérique Auteurs : R. BAYSTON, Auteur Année de publication : 1975 Article en page(s) : p.99-103 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : A system of antibiotic prophylaxis has recently been described which is said to lower the incidence of wound infection in various surgical procedures, and which also evades the problem of increase in resistant bacteria. In the investigation reported here, this system was applied to the prevention of colonisation following shunt surgery and was found to have no beneficial effect. It is suggested that this finding may be peculiar to operations involving the implantation of hollow devices. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] Antibiotic prophylaxis in shunt surgery [Texte imprimé et/ou numérique] / R. BAYSTON, Auteur . - 1975 . - p.99-103. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.99-103 Index. décimale : PER Périodiques Résumé : A system of antibiotic prophylaxis has recently been described which is said to lower the incidence of wound infection in various surgical procedures, and which also evades the problem of increase in resistant bacteria. In the investigation reported here, this system was applied to the prevention of colonisation following shunt surgery and was found to have no beneficial effect. It is suggested that this finding may be peculiar to operations involving the implantation of hollow devices. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451

Serological surveillance of children with CSF shunting devices / R. BAYSTON in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.104-110 Titre : Serological surveillance of children with CSF shunting devices Type de document : Texte imprimé et/ou numérique Auteurs : R. BAYSTON, Auteur Année de publication : 1975 Article en page(s) : p.104-110 Langues : Anglais (eng) Mots-clés : A naturally-occurring, age-related rise in titre of antibody to Staph. albus in both hydrocephalic and non-hydrocephalic children is demonstrated in this report. In view of this finding, the value of serial determinations of antibody titre in children with shunts is discussed in terms of an organised surveillance programme. Index. décimale : PER Périodiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] Serological surveillance of children with CSF shunting devices [Texte imprimé et/ou numérique] / R. BAYSTON, Auteur . - 1975 . - p.104-110. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.104-110 Mots-clés : A naturally-occurring, age-related rise in titre of antibody to Staph. albus in both hydrocephalic and non-hydrocephalic children is demonstrated in this report. In view of this finding, the value of serial determinations of antibody titre in children with shunts is discussed in terms of an organised surveillance programme. Index. décimale : PER Périodiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451

Bacterial colonisation and infection in lesions of the central nervous system / P. A. M. RAINE in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.111-116 Titre : Bacterial colonisation and infection in lesions of the central nervous system Type de document : Texte imprimé et/ou numérique Auteurs : P. A. M. RAINE, Auteur ; D. G. YOUNG, Auteur Année de publication : 1975 Article en page(s) : p.111-116 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : A study was made of the pattern of bacterial colonisation during the first month of life in a group of 116 newborn infants with spina bifida. 55 patients subsequently developed a total of 90 infective episodes and in over three-quarters of these episodes there was a correlation between the infecting and colonising organisms. The principal sites of infection were the lesion, the ventricles and the urinary tract, and infection accounted for 27 of the 35 deaths in the series. Some of the factors governing the pattern of colonisation and the development of infection in newborn patients are discussed. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] Bacterial colonisation and infection in lesions of the central nervous system [Texte imprimé et/ou numérique] / P. A. M. RAINE, Auteur ; D. G. YOUNG, Auteur . - 1975 . - p.111-116. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.111-116 Index. décimale : PER Périodiques Résumé : A study was made of the pattern of bacterial colonisation during the first month of life in a group of 116 newborn infants with spina bifida. 55 patients subsequently developed a total of 90 infective episodes and in over three-quarters of these episodes there was a correlation between the infecting and colonising organisms. The principal sites of infection were the lesion, the ventricles and the urinary tract, and infection accounted for 27 of the 35 deaths in the series. Some of the factors governing the pattern of colonisation and the development of infection in newborn patients are discussed. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451

Mycoplasma meningitis in infants with spina bifida / S. R. WEALTHALL in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.117-122 Titre : Mycoplasma meningitis in infants with spina bifida Type de document : Texte imprimé et/ou numérique Auteurs : S. R. WEALTHALL, Auteur Année de publication : 1975 Article en page(s) : p.117-122 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Infants with myelomeningocele are liable to develop bacterial colonisation of the lesion which, in the case of Gram-negative bacteria, often progresses to meningitis because of the infants' immature immune status. The time and origin of the bacterial colonisation usually are uncertain. This study reports seven cases of meningitis caused by Mycoplasma hominis, an organism not previously reported to cause meningitis. The commensal status of Mycoplasma hominis in the vagina of many women, and its isolation from the mother of one patient in this group, suggests that the infant acquired the organism in the birth canal and that infection developed over a period of days. Routine cultures from the sac or wound did not show the presence of organisms until after the child had developed signs and symptoms of meningitis. Commensal organisms from the vagina may lie dormant for several days within the closed myelomeningocele and their more virulent strains may then produce meningitis. It is suggested that neonatal meningitis may be caused by organisms acquired during birth, as well as by those to which the infant is exposed later. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] Mycoplasma meningitis in infants with spina bifida [Texte imprimé et/ou numérique] / S. R. WEALTHALL, Auteur . - 1975 . - p.117-122. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.117-122 Index. décimale : PER Périodiques Résumé : Infants with myelomeningocele are liable to develop bacterial colonisation of the lesion which, in the case of Gram-negative bacteria, often progresses to meningitis because of the infants' immature immune status. The time and origin of the bacterial colonisation usually are uncertain. This study reports seven cases of meningitis caused by Mycoplasma hominis, an organism not previously reported to cause meningitis. The commensal status of Mycoplasma hominis in the vagina of many women, and its isolation from the mother of one patient in this group, suggests that the infant acquired the organism in the birth canal and that infection developed over a period of days. Routine cultures from the sac or wound did not show the presence of organisms until after the child had developed signs and symptoms of meningitis. Commensal organisms from the vagina may lie dormant for several days within the closed myelomeningocele and their more virulent strains may then produce meningitis. It is suggested that neonatal meningitis may be caused by organisms acquired during birth, as well as by those to which the infant is exposed later. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451

Continence, friends, marriage and children in 51 adults with spina bifida / K. M. LAURENCE in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.123-128 Titre : Continence, friends, marriage and children in 51 adults with spina bifida Type de document : Texte imprimé et/ou numérique Auteurs : K. M. LAURENCE, Auteur ; Ann BERESFORD, Auteur Année de publication : 1975 Article en page(s) : p.123-128 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Fifty-one adults with spina bifida (28 men and 23 women aged between 17 and 56 years) were interviewed in their own homes in South Wales. 17 were completely continent, 10 were incontinent and the remainder were continent to some degree. Seven of the 51 had no close friends but almost half the total had five or more close friends. Of the 29 who were unmarried, nine had a steady relationship but 13 felt that they were disqualified from such a relationship because of their disabilities. 11 men and 11 women were married and a total of 39 pregnancies had come to term, resulting in 32 normal children, five stillbirths (two with anencephaly) and two children with spina bifida. The risk of having an affected offspring when one of the parents has spina bifida (based on the combined London, Munster and Cardiff series) is 1 in 23. It is suggested that the children now growing up who have received 'total care' will be more handicapped than the adults in this series. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] Continence, friends, marriage and children in 51 adults with spina bifida [Texte imprimé et/ou numérique] / K. M. LAURENCE, Auteur ; Ann BERESFORD, Auteur . - 1975 . - p.123-128. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.123-128 Index. décimale : PER Périodiques Résumé : Fifty-one adults with spina bifida (28 men and 23 women aged between 17 and 56 years) were interviewed in their own homes in South Wales. 17 were completely continent, 10 were incontinent and the remainder were continent to some degree. Seven of the 51 had no close friends but almost half the total had five or more close friends. Of the 29 who were unmarried, nine had a steady relationship but 13 felt that they were disqualified from such a relationship because of their disabilities. 11 men and 11 women were married and a total of 39 pregnancies had come to term, resulting in 32 normal children, five stillbirths (two with anencephaly) and two children with spina bifida. The risk of having an affected offspring when one of the parents has spina bifida (based on the combined London, Munster and Cardiff series) is 1 in 23. It is suggested that the children now growing up who have received 'total care' will be more handicapped than the adults in this series. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451

The effects of hydrocephalus on intelligence, visual perception and school attainment / Brian TEW in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.129-134 Titre : The effects of hydrocephalus on intelligence, visual perception and school attainment Type de document : Texte imprimé et/ou numérique Auteurs : Brian TEW, Auteur ; K. M. LAURENCE, Auteur Année de publication : 1975 Article en page(s) : p.129-134 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : A group of 59 children with spina bifida, and a group of matched controls, were given detailed psychological and educational tests at five and seven years. The scores of the control group were similar to the national figures. The scores of the children with spina bifida only (without hydrocephalus) were closest to normal, but still below average. Those with spontaneously arrested hydrocephalus were in the backward range of abilities, and those with shunt-treated hydrocephalus had scores which generally were incompatible with normal levels of intelligence and attainment. Abnormal visuo-perceptual functioning closely correlated with defects in intelligence. The results of the school-attainment tests paralleled the distribution of intelligence but many of the children were found to be functioning below expectation for both age and measured intelligence. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] The effects of hydrocephalus on intelligence, visual perception and school attainment [Texte imprimé et/ou numérique] / Brian TEW, Auteur ; K. M. LAURENCE, Auteur . - 1975 . - p.129-134. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.129-134 Index. décimale : PER Périodiques Résumé : A group of 59 children with spina bifida, and a group of matched controls, were given detailed psychological and educational tests at five and seven years. The scores of the control group were similar to the national figures. The scores of the children with spina bifida only (without hydrocephalus) were closest to normal, but still below average. Those with spontaneously arrested hydrocephalus were in the backward range of abilities, and those with shunt-treated hydrocephalus had scores which generally were incompatible with normal levels of intelligence and attainment. Abnormal visuo-perceptual functioning closely correlated with defects in intelligence. The results of the school-attainment tests paralleled the distribution of intelligence but many of the children were found to be functioning below expectation for both age and measured intelligence. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451

Diverticulation of the cerebral ventricles: a cause of progressive focal encephalopathy / Raymond D. ADAMS in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.135-137 Titre : Diverticulation of the cerebral ventricles: a cause of progressive focal encephalopathy Type de document : Texte imprimé et/ou numérique Auteurs : Raymond D. ADAMS, Auteur Année de publication : 1975 Article en page(s) : p.135-137 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Diverticulation of the lateral ventricles of the brain has received little attention in the literature on hydrocephalus. From clinical observations on one child and one adult with diverticulation, it is apparent that force of CSF within the diverticulum is greater than that against the normal parts of the ventricular wall. In both cases, regression of focal symptoms occurred after insertion of a shunt. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] Diverticulation of the cerebral ventricles: a cause of progressive focal encephalopathy [Texte imprimé et/ou numérique] / Raymond D. ADAMS, Auteur . - 1975 . - p.135-137. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.135-137 Index. décimale : PER Périodiques Résumé : Diverticulation of the lateral ventricles of the brain has received little attention in the literature on hydrocephalus. From clinical observations on one child and one adult with diverticulation, it is apparent that force of CSF within the diverticulum is greater than that against the normal parts of the ventricular wall. In both cases, regression of focal symptoms occurred after insertion of a shunt. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451

Cerebrospinal fluid pressure-gradients in spina bifida cystica, with special reference to the Arnold-Chiari malformation and aqueductal stenosis / Bernard WILLIAMS in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.138-150 Titre : Cerebrospinal fluid pressure-gradients in spina bifida cystica, with special reference to the Arnold-Chiari malformation and aqueductal stenosis Type de document : Texte imprimé et/ou numérique Auteurs : Bernard WILLIAMS, Auteur Année de publication : 1975 Article en page(s) : p.138-150 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Ten infants with spina bifida cystica were investigated during life by simultaneous ventricular and intraspinal CSF pressure recordings, and 11 post-mortem specimens were studied by means of crystic resin castings of the ventricles. The results indicate marked pressure differentials between the lateral ventricles and intraspinal CSF pathways, which contribute to the moulding of the Arnold-Chiari malformation as a sliding hernia. Similar pressure differentials may exist at the incisura, with moulding of tissues producing blockage of the aqueduct and the subarachnoid pathways. A valvular action was demonstrated, in which baseline pressure differences were exaggerated by the infant's straining (e.g. crying, sucking), and it seems that complete dissociation between the two pressures may develop as a result of periods of partial dissociation. Removal of the meningocele sac increased the peaks in recordings of intraspinal pressure produced by straining. If it is carried out when there is a valvular effect, it seems that it will hasten the onset of established ventriculo-spinal pressure dissociation and uncompensated hydrocephalus by leading to impaction of the Arnold-Chiari malformation in the foramen magnum. The results indicate that even after birth the CSF pathways of babies with spina bifida cystica are in a plastic and changeable condition, with competition between constricting and distending forces. The demonstration that pressures tend to be low in the spine and to become lower before exacerbation of hydrocephalus suggests that all the intracranial manifestations of spina bifida cystica may be due to low intraspinal pressure, which results from initial failure of the neural tube to close during embryogenesis. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] Cerebrospinal fluid pressure-gradients in spina bifida cystica, with special reference to the Arnold-Chiari malformation and aqueductal stenosis [Texte imprimé et/ou numérique] / Bernard WILLIAMS, Auteur . - 1975 . - p.138-150. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.138-150 Index. décimale : PER Périodiques Résumé : Ten infants with spina bifida cystica were investigated during life by simultaneous ventricular and intraspinal CSF pressure recordings, and 11 post-mortem specimens were studied by means of crystic resin castings of the ventricles. The results indicate marked pressure differentials between the lateral ventricles and intraspinal CSF pathways, which contribute to the moulding of the Arnold-Chiari malformation as a sliding hernia. Similar pressure differentials may exist at the incisura, with moulding of tissues producing blockage of the aqueduct and the subarachnoid pathways. A valvular action was demonstrated, in which baseline pressure differences were exaggerated by the infant's straining (e.g. crying, sucking), and it seems that complete dissociation between the two pressures may develop as a result of periods of partial dissociation. Removal of the meningocele sac increased the peaks in recordings of intraspinal pressure produced by straining. If it is carried out when there is a valvular effect, it seems that it will hasten the onset of established ventriculo-spinal pressure dissociation and uncompensated hydrocephalus by leading to impaction of the Arnold-Chiari malformation in the foramen magnum. The results indicate that even after birth the CSF pathways of babies with spina bifida cystica are in a plastic and changeable condition, with competition between constricting and distending forces. The demonstration that pressures tend to be low in the spine and to become lower before exacerbation of hydrocephalus suggests that all the intracranial manifestations of spina bifida cystica may be due to low intraspinal pressure, which results from initial failure of the neural tube to close during embryogenesis. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451

Reconstitution of the cerebral cortical mantle in shunt-corrected hydrocephalus / Robert C. RUBIN in Developmental Medicine & Child Neurology, S35 (December 1975)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > S35 (December 1975) . - p.151-156 Titre : Reconstitution of the cerebral cortical mantle in shunt-corrected hydrocephalus Type de document : Texte imprimé et/ou numérique Auteurs : Robert C. RUBIN, Auteur ; Gerald M. HOCHWALD, Auteur ; Fred J. EPSTEIN, Auteur ; Melvin TIELL, Auteur ; Bolek LIWNICZ, Auteur Année de publication : 1975 Article en page(s) : p.151-156 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The purpose of this study was to ascertain the sequence of events and the cellular constituents involved in reconstituting the cortical mantle after ventricular shunting. The subjects were severely hydrocephalic adult cats. After insertion of a shunt, the ventricular system rapidly returned to normal size and there was gross reconstitution of the cortical mantle. However, there still remained in the cortical mantle many of the histological changes seen before insertion of the shunt. The effect of hydrocephalus is mainly upon axons in the periventricular white matter. The axons become stretched and finally disrupted, resulting in disintegration of the surrounding myelin. In the absence of axons, remyelination cannot take place. It would seem, therefore, that prompt reversal of hydrocephalus is necessary in order to preserve the anatomical and functional integrity of the brain. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] Reconstitution of the cerebral cortical mantle in shunt-corrected hydrocephalus [Texte imprimé et/ou numérique] / Robert C. RUBIN, Auteur ; Gerald M. HOCHWALD, Auteur ; Fred J. EPSTEIN, Auteur ; Melvin TIELL, Auteur ; Bolek LIWNICZ, Auteur . - 1975 . - p.151-156. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > S35 (December 1975) . - p.151-156 Index. décimale : PER Périodiques Résumé : The purpose of this study was to ascertain the sequence of events and the cellular constituents involved in reconstituting the cortical mantle after ventricular shunting. The subjects were severely hydrocephalic adult cats. After insertion of a shunt, the ventricular system rapidly returned to normal size and there was gross reconstitution of the cortical mantle. However, there still remained in the cortical mantle many of the histological changes seen before insertion of the shunt. The effect of hydrocephalus is mainly upon axons in the periventricular white matter. The axons become stretched and finally disrupted, resulting in disintegration of the surrounding myelin. In the absence of axons, remyelination cannot take place. It would seem, therefore, that prompt reversal of hydrocephalus is necessary in order to preserve the anatomical and functional integrity of the brain. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451