Editorial: Context and conduct, and accessibility in scientific reporting / Tom O'CONNOR in Journal of Child Psychology and Psychiatry, 52-11 (November 2011)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 52-11 (November 2011) . - p.1109-1110 Titre : Editorial: Context and conduct, and accessibility in scientific reporting Type de document : Texte imprimé et/ou numérique Auteurs : Tom O'CONNOR, Auteur Année de publication : 2011 Article en page(s) : p.1109-1110 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02476.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=144 [article] Editorial: Context and conduct, and accessibility in scientific reporting [Texte imprimé et/ou numérique] / Tom O'CONNOR, Auteur . - 2011 . - p.1109-1110. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 52-11 (November 2011) . - p.1109-1110 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02476.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=144

Editorial: Measurements and perceptions in child psychology and psychiatry / Tom O'CONNOR in Journal of Child Psychology and Psychiatry, 53-10 (October 2012)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 53-10 (October 2012) . - p.1007-8 Titre : Editorial: Measurements and perceptions in child psychology and psychiatry Type de document : Texte imprimé et/ou numérique Auteurs : Tom O'CONNOR, Auteur Année de publication : 2012 Article en page(s) : p.1007-8 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02619.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=181 [article] Editorial: Measurements and perceptions in child psychology and psychiatry [Texte imprimé et/ou numérique] / Tom O'CONNOR, Auteur . - 2012 . - p.1007-8. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 53-10 (October 2012) . - p.1007-8 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02619.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=181

Neonatal DNA methylation and early-onset conduct problems: A genome-wide, prospective study / Charlotte A. M. CECIL in Development and Psychopathology, 30-2 (May 2018)  

Public ISBD [article]  inDevelopment and Psychopathology > 30-2 (May 2018) . - p.383-397 Titre : Neonatal DNA methylation and early-onset conduct problems: A genome-wide, prospective study Type de document : Texte imprimé et/ou numérique Auteurs : Charlotte A. M. CECIL, Auteur ; Esther WALTON, Auteur ; Sara R. JAFFEE, Auteur ; Tom O'CONNOR, Auteur ; Barbara MAUGHAN, Auteur ; Caroline L. RELTON, Auteur ; Rebecca G. SMITH, Auteur ; Wendy MCARDLE, Auteur ; Tom R. GAUNT, Auteur ; Isabelle OUELLET-MORIN, Auteur ; Edward D. BARKER, Auteur Article en page(s) : p.383-397 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Early-onset conduct problems (CP) are a key predictor of adult criminality and poor mental health. While previous studies suggest that both genetic and environmental risks play an important role in the development of early-onset CP, little is known about potential biological processes underlying these associations. In this study, we examined prospective associations between DNA methylation (cord blood at birth) and trajectories of CP (4–13 years), using data drawn from the Avon Longitudinal Study of Parents and Children. Methylomic variation at seven loci across the genome (false discovery rate < 0.05) differentiated children who go on to develop early-onset (n = 174) versus low (n = 86) CP, including sites in the vicinity of the monoglyceride lipase (MGLL) gene (involved in endocannabinoid signaling and pain perception). Subthreshold associations in the vicinity of three candidate genes for CP (monoamine oxidase A [MAOA], brain-derived neurotrophic factor [BDNF], and FK506 binding protein 5 [FKBP5]) were also identified. Within the early-onset CP group, methylation levels of the identified sites did not distinguish children who will go on to persist versus desist in CP behavior over time. Overall, we found that several of the identified sites correlated with prenatal exposures, and none were linked to known genetic methylation quantitative trait loci. Findings contribute to a better understanding of epigenetic patterns associated with early-onset CP. En ligne : http://dx.doi.org/10.1017/S095457941700092X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=358 [article] Neonatal DNA methylation and early-onset conduct problems: A genome-wide, prospective study [Texte imprimé et/ou numérique] / Charlotte A. M. CECIL, Auteur ; Esther WALTON, Auteur ; Sara R. JAFFEE, Auteur ; Tom O'CONNOR, Auteur ; Barbara MAUGHAN, Auteur ; Caroline L. RELTON, Auteur ; Rebecca G. SMITH, Auteur ; Wendy MCARDLE, Auteur ; Tom R. GAUNT, Auteur ; Isabelle OUELLET-MORIN, Auteur ; Edward D. BARKER, Auteur . - p.383-397. Langues : Anglais (eng) in Development and Psychopathology > 30-2 (May 2018) . - p.383-397 Index. décimale : PER Périodiques Résumé : Early-onset conduct problems (CP) are a key predictor of adult criminality and poor mental health. While previous studies suggest that both genetic and environmental risks play an important role in the development of early-onset CP, little is known about potential biological processes underlying these associations. In this study, we examined prospective associations between DNA methylation (cord blood at birth) and trajectories of CP (4–13 years), using data drawn from the Avon Longitudinal Study of Parents and Children. Methylomic variation at seven loci across the genome (false discovery rate < 0.05) differentiated children who go on to develop early-onset (n = 174) versus low (n = 86) CP, including sites in the vicinity of the monoglyceride lipase (MGLL) gene (involved in endocannabinoid signaling and pain perception). Subthreshold associations in the vicinity of three candidate genes for CP (monoamine oxidase A [MAOA], brain-derived neurotrophic factor [BDNF], and FK506 binding protein 5 [FKBP5]) were also identified. Within the early-onset CP group, methylation levels of the identified sites did not distinguish children who will go on to persist versus desist in CP behavior over time. Overall, we found that several of the identified sites correlated with prenatal exposures, and none were linked to known genetic methylation quantitative trait loci. Findings contribute to a better understanding of epigenetic patterns associated with early-onset CP. En ligne : http://dx.doi.org/10.1017/S095457941700092X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=358

translational research in practice / Tom O'CONNOR in Journal of Child Psychology and Psychiatry, 54-11 (November 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-11 (November 2013) . - p.1153-1154 Titre : translational research in practice Type de document : Texte imprimé et/ou numérique Auteurs : Tom O'CONNOR, Auteur Article en page(s) : p.1153-1154 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Readers will now be familiar with the notion of ‘translational research’. According to its generally acknowledged progenitor, the National Institutes of Health (NIH) in the US, this is a kind of research agenda focused on translating or applying the research findings from basic/preclinical studies to human studies and perhaps most especially treatment trials; and, the translation of clinical research findings to the community so that evidence-based best practice is adopted. En ligne : http://dx.doi.org/10.1111/jcpp.12163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217 [article] translational research in practice [Texte imprimé et/ou numérique] / Tom O'CONNOR, Auteur . - p.1153-1154. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-11 (November 2013) . - p.1153-1154 Index. décimale : PER Périodiques Résumé : Readers will now be familiar with the notion of ‘translational research’. According to its generally acknowledged progenitor, the National Institutes of Health (NIH) in the US, this is a kind of research agenda focused on translating or applying the research findings from basic/preclinical studies to human studies and perhaps most especially treatment trials; and, the translation of clinical research findings to the community so that evidence-based best practice is adopted. En ligne : http://dx.doi.org/10.1111/jcpp.12163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217

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