Reward Circuitry Function in Autism During Face Anticipation and Outcomes / Gabriel S. DICHTER in Journal of Autism and Developmental Disorders, 42-2 (February 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-2 (February 2012) . - p.147-160 Titre : Reward Circuitry Function in Autism During Face Anticipation and Outcomes Type de document : Texte imprimé et/ou numérique Auteurs : Gabriel S. DICHTER, Auteur ; J. Anthony RICHEY, Auteur ; Alison M. RITTENBERG, Auteur ; Antoinette SABATINO-DICRISCIO, Auteur ; James W. BODFISH, Auteur Année de publication : 2012 Article en page(s) : p.147-160 Langues : Anglais (eng) Mots-clés : Autism  Nucleus accumbens  Anticipation  Functional magnetic resonance imaging  Social cognition  Reward Index. décimale : PER Périodiques Résumé : The aim of this study was to investigate reward circuitry responses in autism during reward anticipation and outcomes for monetary and social rewards. During monetary anticipation, participants with autism spectrum disorders (ASDs) showed hypoactivation in right nucleus accumbens and hyperactivation in right hippocampus, whereas during monetary outcomes, participants with ASDs showed hyperactivation in left midfrontal and anterior cingulate gyrus. Groups did not differ in nucleus accumbens responses to faces. The ASD group demonstrated hyperactivation in bilateral amygdala during face anticipation that predicted social symptom severity and in bilateral insular cortex during face outcomes. These results add to the growing body of evidence that autism is characterized by altered functioning of reward circuitry. Additionally, atypical amygdala activation during the processing of social rewards may contribute to the development or expression of autistic features. En ligne : http://dx.doi.org/10.1007/s10803-011-1221-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=151 [article] Reward Circuitry Function in Autism During Face Anticipation and Outcomes [Texte imprimé et/ou numérique] / Gabriel S. DICHTER, Auteur ; J. Anthony RICHEY, Auteur ; Alison M. RITTENBERG, Auteur ; Antoinette SABATINO-DICRISCIO, Auteur ; James W. BODFISH, Auteur . - 2012 . - p.147-160. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-2 (February 2012) . - p.147-160 Mots-clés : Autism  Nucleus accumbens  Anticipation  Functional magnetic resonance imaging  Social cognition  Reward Index. décimale : PER Périodiques Résumé : The aim of this study was to investigate reward circuitry responses in autism during reward anticipation and outcomes for monetary and social rewards. During monetary anticipation, participants with autism spectrum disorders (ASDs) showed hypoactivation in right nucleus accumbens and hyperactivation in right hippocampus, whereas during monetary outcomes, participants with ASDs showed hyperactivation in left midfrontal and anterior cingulate gyrus. Groups did not differ in nucleus accumbens responses to faces. The ASD group demonstrated hyperactivation in bilateral amygdala during face anticipation that predicted social symptom severity and in bilateral insular cortex during face outcomes. These results add to the growing body of evidence that autism is characterized by altered functioning of reward circuitry. Additionally, atypical amygdala activation during the processing of social rewards may contribute to the development or expression of autistic features. En ligne : http://dx.doi.org/10.1007/s10803-011-1221-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=151

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