[article]
| Titre : |
The Broader Autism Phenotype in Simplex and Multiplex Families |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Jennifer GERDTS, Auteur ; Raphael BERNIER, Auteur ; Geraldine DAWSON, Auteur ; Annette ESTES, Auteur |
| Année de publication : |
2013 |
| Article en page(s) : |
p.1597-1605 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Autism spectrum disorder Simplex Multiplex Broader autism phenotype |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Mothers, fathers, and siblings from 87 multiplex (M-mothers, M-fathers, and M-siblings) and 41 simplex (S-mothers, S-fathers, and S-siblings) Autism spectrum disorder families were assessed using the Broader Phenotype Autism Symptom Scale. S-mothers, S-fathers, and S-siblings showed more social interest and were more expressive in their use of nonverbal communication compared to M-mothers, M-fathers, and M-siblings. Conversational skills were also improved in S-fathers and S-siblings compared to M-fathers and M-siblings. S-siblings showed significantly lower rigidity and intense interests compared to M-siblings. The decreased number and intensity of broader autism phenotype traits observed in parents and siblings within simplex families provide behavioral evidence consistent with findings of increased de novo genetic events in simplex families. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-012-1706-6 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=202 |
in Journal of Autism and Developmental Disorders > 43-7 (July 2013) . - p.1597-1605
[article] The Broader Autism Phenotype in Simplex and Multiplex Families [Texte imprimé et/ou numérique] / Jennifer GERDTS, Auteur ; Raphael BERNIER, Auteur ; Geraldine DAWSON, Auteur ; Annette ESTES, Auteur . - 2013 . - p.1597-1605. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 43-7 (July 2013) . - p.1597-1605
| Mots-clés : |
Autism spectrum disorder Simplex Multiplex Broader autism phenotype |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Mothers, fathers, and siblings from 87 multiplex (M-mothers, M-fathers, and M-siblings) and 41 simplex (S-mothers, S-fathers, and S-siblings) Autism spectrum disorder families were assessed using the Broader Phenotype Autism Symptom Scale. S-mothers, S-fathers, and S-siblings showed more social interest and were more expressive in their use of nonverbal communication compared to M-mothers, M-fathers, and M-siblings. Conversational skills were also improved in S-fathers and S-siblings compared to M-fathers and M-siblings. S-siblings showed significantly lower rigidity and intense interests compared to M-siblings. The decreased number and intensity of broader autism phenotype traits observed in parents and siblings within simplex families provide behavioral evidence consistent with findings of increased de novo genetic events in simplex families. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-012-1706-6 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=202 |
|
The Broader Autism Phenotype in Simplex and Multiplex Families in Journal of Autism and Developmental Disorders, 43-7 (July 2013)
