Maternal Vitamin D Levels and the Autism Phenotype Among Offspring / Andrew J. O. WHITEHOUSE in Journal of Autism and Developmental Disorders, 43-7 (July 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-7 (July 2013) . - p.1495-1504 Titre : Maternal Vitamin D Levels and the Autism Phenotype Among Offspring Type de document : Texte imprimé et/ou numérique Auteurs : Andrew J. O. WHITEHOUSE, Auteur ; Barbara J. HOLT, Auteur ; Michael SERRALHA, Auteur ; Patrick G HOLT, Auteur ; Prue H. HART, Auteur ; Merci M. H. KUSEL, Auteur Année de publication : 2013 Article en page(s) : p.1495-1504 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Autistic-like traits  Vitamin D  Prenatal  Pregnancy  Environment Index. décimale : PER Périodiques Résumé : We tested whether maternal vitamin D insufficiency during pregnancy is related to the autism phenotype. Serum 25(OH)-vitamin D concentrations of 929 women were measured at 18 weeks’ pregnancy. The mothers of the three children with a clinical diagnosis of autism spectrum disorder had 25(OH)-vitamin D concentrations above the population mean. The offspring of 406 women completed the Autism-Spectrum Quotient in early adulthood. Maternal 25(OH)-vitamin D concentrations were unrelated to offspring scores on the majority of scales. However, offspring of mothers with low 25(OH)-vitamin D concentrations (49 nmol/L) were at increased risk for ‘high’ scores (?2SD above mean) on the Attention Switching subscale (odds ratio: 5.46, 95 % confidence interval: 1.29, 23.05). The involvement of maternal vitamin D during pregnancy in autism requires continued investigation. En ligne : http://dx.doi.org/10.1007/s10803-012-1676-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=202 [article] Maternal Vitamin D Levels and the Autism Phenotype Among Offspring [Texte imprimé et/ou numérique] / Andrew J. O. WHITEHOUSE, Auteur ; Barbara J. HOLT, Auteur ; Michael SERRALHA, Auteur ; Patrick G HOLT, Auteur ; Prue H. HART, Auteur ; Merci M. H. KUSEL, Auteur . - 2013 . - p.1495-1504. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-7 (July 2013) . - p.1495-1504 Mots-clés : Autism spectrum disorder  Autistic-like traits  Vitamin D  Prenatal  Pregnancy  Environment Index. décimale : PER Périodiques Résumé : We tested whether maternal vitamin D insufficiency during pregnancy is related to the autism phenotype. Serum 25(OH)-vitamin D concentrations of 929 women were measured at 18 weeks’ pregnancy. The mothers of the three children with a clinical diagnosis of autism spectrum disorder had 25(OH)-vitamin D concentrations above the population mean. The offspring of 406 women completed the Autism-Spectrum Quotient in early adulthood. Maternal 25(OH)-vitamin D concentrations were unrelated to offspring scores on the majority of scales. However, offspring of mothers with low 25(OH)-vitamin D concentrations (49 nmol/L) were at increased risk for ‘high’ scores (?2SD above mean) on the Attention Switching subscale (odds ratio: 5.46, 95 % confidence interval: 1.29, 23.05). The involvement of maternal vitamin D during pregnancy in autism requires continued investigation. En ligne : http://dx.doi.org/10.1007/s10803-012-1676-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=202

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