A Pilot Randomised Control Trial Exploring the Feasibility and Acceptability of Delivering a Personalised Modular Psychological Intervention for Anxiety Experienced by Autistic Adults: Personalised Anxiety Treatment-Autism (PAT-A) / Jacqui RODGERS in Journal of Autism and Developmental Disorders, 54-11 (November)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 54-11 (November) . - p.4045-4060 Titre : A Pilot Randomised Control Trial Exploring the Feasibility and Acceptability of Delivering a Personalised Modular Psychological Intervention for Anxiety Experienced by Autistic Adults: Personalised Anxiety Treatment-Autism (PAT-A) Type de document : Texte imprimé et/ou numérique Auteurs : Jacqui RODGERS, Auteur ; Samuel BRICE, Auteur ; Patrick WELSH, Auteur ; Barry INGHAM, Auteur ; Colin WILSON, Auteur ; Gemma EVANS, Auteur ; Katie STEELE, Auteur ; Emily CROPPER, Auteur ; Ann LE COUTEUR, Auteur ; Mark FREESTON, Auteur ; Jeremy R. PARR, Auteur Article en page(s) : p.4045-4060 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Anxiety is commonly experienced by autistic people and impacts on quality of life and social participation. New anxiety interventions are required to effectively meet the needs of autistic people. Personalised Anxiety Treatment-Autism (PAT-A©) is a bespoke, modular approach to treating anxiety in up to 12 sessions. This study explored the feasibility and acceptability of delivering PAT-A© in the UK National Health Service (NHS). A single-blind randomised controlled trial design. Thirty-four autistic adults were recruited via clinical services and randomised to receive either PAT-A© or enhanced treatment as usual (CCSP). Outcome assessments relating to anxiety, quality of life and related constructs were completed at baseline, immediately post intervention; and at 3 and 12 months. Seventy-one percent of the PAT-A© group and 65% of the CCSP met diagnostic threshold for at least three anxiety disorders. Retention was good across both groups, with 82% (N = 14/17) completing the full course of PAT-A© and 71% (N = 12/17) attending both psychoeducational sessions in CCSP. 94% in PAT-A© and 82% in CCSP completed some follow up assessment 3 months post-intervention. Thematic analysis of interview data revealed that many participants valued the personalised approach, developed transferable skills and experienced positive changes to their anxiety. Participants were willing to be recruited and randomised, PAT-A© was feasible to deliver in the NHS and the trial methods and materials were acceptable. Our findings indicate that a fully powered clinical and cost-effectiveness trial of PAT-A© is warranted. En ligne : https://doi.org/10.1007/s10803-023-06112-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=536 [article] A Pilot Randomised Control Trial Exploring the Feasibility and Acceptability of Delivering a Personalised Modular Psychological Intervention for Anxiety Experienced by Autistic Adults: Personalised Anxiety Treatment-Autism (PAT-A) [Texte imprimé et/ou numérique] / Jacqui RODGERS, Auteur ; Samuel BRICE, Auteur ; Patrick WELSH, Auteur ; Barry INGHAM, Auteur ; Colin WILSON, Auteur ; Gemma EVANS, Auteur ; Katie STEELE, Auteur ; Emily CROPPER, Auteur ; Ann LE COUTEUR, Auteur ; Mark FREESTON, Auteur ; Jeremy R. PARR, Auteur . - p.4045-4060. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 54-11 (November) . - p.4045-4060 Index. décimale : PER Périodiques Résumé : Anxiety is commonly experienced by autistic people and impacts on quality of life and social participation. New anxiety interventions are required to effectively meet the needs of autistic people. Personalised Anxiety Treatment-Autism (PAT-A©) is a bespoke, modular approach to treating anxiety in up to 12 sessions. This study explored the feasibility and acceptability of delivering PAT-A© in the UK National Health Service (NHS). A single-blind randomised controlled trial design. Thirty-four autistic adults were recruited via clinical services and randomised to receive either PAT-A© or enhanced treatment as usual (CCSP). Outcome assessments relating to anxiety, quality of life and related constructs were completed at baseline, immediately post intervention; and at 3 and 12 months. Seventy-one percent of the PAT-A© group and 65% of the CCSP met diagnostic threshold for at least three anxiety disorders. Retention was good across both groups, with 82% (N = 14/17) completing the full course of PAT-A© and 71% (N = 12/17) attending both psychoeducational sessions in CCSP. 94% in PAT-A© and 82% in CCSP completed some follow up assessment 3 months post-intervention. Thematic analysis of interview data revealed that many participants valued the personalised approach, developed transferable skills and experienced positive changes to their anxiety. Participants were willing to be recruited and randomised, PAT-A© was feasible to deliver in the NHS and the trial methods and materials were acceptable. Our findings indicate that a fully powered clinical and cost-effectiveness trial of PAT-A© is warranted. En ligne : https://doi.org/10.1007/s10803-023-06112-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=536

Practitioner Review: Schizophrenia spectrum disorders and the at-risk mental state for psychosis in children and adolescents – evidence-based management approaches / Paul A. TIFFIN in Journal of Child Psychology and Psychiatry, 54-11 (November 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-11 (November 2013) . - p.1155-1175 Titre : Practitioner Review: Schizophrenia spectrum disorders and the at-risk mental state for psychosis in children and adolescents – evidence-based management approaches Type de document : Texte imprimé et/ou numérique Auteurs : Paul A. TIFFIN, Auteur ; Patrick WELSH, Auteur Article en page(s) : p.1155-1175 Langues : Anglais (eng) Mots-clés : Schizophrenia  psychosis  risk syndrome  prodrome  early recognition Index. décimale : PER Périodiques Résumé : Background Schizophrenia spectrum disorders are severe mental illnesses which often result in significant distress and disability. Attempts have been made to prospectively identify and treat young people viewed as at high risk of impending nonaffective psychosis. Once a schizophrenia spectrum disorder has developed, prompt identification and management is required. Methods This article reviews the literature relating to the assessment and management of ‘at-risk mental states’ (ARMS) and the treatment of schizophrenia spectrum disorders in children and adolescents. A systematic search of the literature was undertaken using EMBASE, MEDLINE, PsycINFO databases for the period January 1970–December 2012. Results Evidence suggests that young people fulfilling the ARMS criteria are at high risk of adverse mental health outcomes but that the majority do not develop nonaffective psychosis over the medium term. Although clinical trial findings have been inconsistent, psychosocial approaches, such as cognitive behaviour therapy, may reduce the risk of transition to psychosis and improve some symptoms, at least over the short term. The effectiveness of psychotropic medication for the ARMS is uncertain although there is accumulating evidence for potential adverse effects of antipsychotic medication, even at low dose, in this population. For the schizophrenias, clinical trial findings suggest that, as in adults, antipsychotics should be selected on the basis of side-effect profile although clozapine may be helpful in treatment refractory illness. There are almost no studies of psychosocial treatments for schizophrenia in young people under 18, and some caution must be exercised when extrapolating the findings of adult studies to younger individuals. Conclusions A stepped care approach to the ARMS in young people represents a plausible potential management approach for those at high risk of serious mental health problems. However, predictive models currently lack precision and should focus on accurately identifying those at high risk for a variety of poor outcomes who may benefit most from intervention. There is also an urgent need for age-specific research in the area of psychosocial treatments for children and adolescents with schizophrenia. En ligne : http://dx.doi.org/10.1111/jcpp.12136 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217 [article] Practitioner Review: Schizophrenia spectrum disorders and the at-risk mental state for psychosis in children and adolescents – evidence-based management approaches [Texte imprimé et/ou numérique] / Paul A. TIFFIN, Auteur ; Patrick WELSH, Auteur . - p.1155-1175. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-11 (November 2013) . - p.1155-1175 Mots-clés : Schizophrenia  psychosis  risk syndrome  prodrome  early recognition Index. décimale : PER Périodiques Résumé : Background Schizophrenia spectrum disorders are severe mental illnesses which often result in significant distress and disability. Attempts have been made to prospectively identify and treat young people viewed as at high risk of impending nonaffective psychosis. Once a schizophrenia spectrum disorder has developed, prompt identification and management is required. Methods This article reviews the literature relating to the assessment and management of ‘at-risk mental states’ (ARMS) and the treatment of schizophrenia spectrum disorders in children and adolescents. A systematic search of the literature was undertaken using EMBASE, MEDLINE, PsycINFO databases for the period January 1970–December 2012. Results Evidence suggests that young people fulfilling the ARMS criteria are at high risk of adverse mental health outcomes but that the majority do not develop nonaffective psychosis over the medium term. Although clinical trial findings have been inconsistent, psychosocial approaches, such as cognitive behaviour therapy, may reduce the risk of transition to psychosis and improve some symptoms, at least over the short term. The effectiveness of psychotropic medication for the ARMS is uncertain although there is accumulating evidence for potential adverse effects of antipsychotic medication, even at low dose, in this population. For the schizophrenias, clinical trial findings suggest that, as in adults, antipsychotics should be selected on the basis of side-effect profile although clozapine may be helpful in treatment refractory illness. There are almost no studies of psychosocial treatments for schizophrenia in young people under 18, and some caution must be exercised when extrapolating the findings of adult studies to younger individuals. Conclusions A stepped care approach to the ARMS in young people represents a plausible potential management approach for those at high risk of serious mental health problems. However, predictive models currently lack precision and should focus on accurately identifying those at high risk for a variety of poor outcomes who may benefit most from intervention. There is also an urgent need for age-specific research in the area of psychosocial treatments for children and adolescents with schizophrenia. En ligne : http://dx.doi.org/10.1111/jcpp.12136 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217

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