[article] 
inJournal of Autism and Developmental Disorders > 45-7 (July 2015) . - p.1925-1937

Titre :	Symptoms of Autism in Males with Fragile X Syndrome: A Comparison to Nonsyndromic ASD Using Current ADI-R Scores
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Andrea MCDUFFIE, Auteur ; Angela John THURMAN, Auteur ; Randi J. HAGERMAN, Auteur ; Leonard ABBEDUTO, Auteur
Année de publication :	2015
Article en page(s) :	p.1925-1937
Langues :	Anglais (eng)
Mots-clés :	Autism spectrum disorder  Fragile X syndrome  ADI-R
Index. décimale :	PER Périodiques
Résumé :	Symptoms of autism are frequent in males with fragile X syndrome (FXS), but it is not clear whether symptom profiles differ from those of nonsyndromic ASD. Using individual item scores from the Autism Diagnostic Inventory-Revised, we examined which current symptoms of autism differed in boys with FXS relative to same-aged boys diagnosed with nonsyndromic ASD. In addition, different subsamples of participants were matched on autism diagnostic status and severity of autism symptoms. Between-group comparisons revealed that boys with FXS showed significantly less impairment in Social Smiling than did age-, diagnostic-, and severity-matched boys with nonsyndromic ASD. Severity-matched boys with FXS showed more impairment in complex mannerisms than did boys with nonsyndromic ASD. Behavioral differences between FXS and nonsyndromic ASD may be of theoretical importance in understanding the causes and correlates of ASD in FXS and in developing and implementing appropriate treatments.
En ligne :	http://dx.doi.org/10.1007/s10803-013-2013-6
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261

[article] Symptoms of Autism in Males with Fragile X Syndrome: A Comparison to Nonsyndromic ASD Using Current ADI-R Scores [Texte imprimé et/ou numérique] / Andrea MCDUFFIE, Auteur ; Angela John THURMAN, Auteur ; Randi J. HAGERMAN, Auteur ; Leonard ABBEDUTO, Auteur . - 2015 . - p.1925-1937.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-7 (July 2015) . - p.1925-1937

Mots-clés :	Autism spectrum disorder  Fragile X syndrome  ADI-R
Index. décimale :	PER Périodiques
Résumé :	Symptoms of autism are frequent in males with fragile X syndrome (FXS), but it is not clear whether symptom profiles differ from those of nonsyndromic ASD. Using individual item scores from the Autism Diagnostic Inventory-Revised, we examined which current symptoms of autism differed in boys with FXS relative to same-aged boys diagnosed with nonsyndromic ASD. In addition, different subsamples of participants were matched on autism diagnostic status and severity of autism symptoms. Between-group comparisons revealed that boys with FXS showed significantly less impairment in Social Smiling than did age-, diagnostic-, and severity-matched boys with nonsyndromic ASD. Severity-matched boys with FXS showed more impairment in complex mannerisms than did boys with nonsyndromic ASD. Behavioral differences between FXS and nonsyndromic ASD may be of theoretical importance in understanding the causes and correlates of ASD in FXS and in developing and implementing appropriate treatments.
En ligne :	http://dx.doi.org/10.1007/s10803-013-2013-6
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261