An integrative evolutionary framework for psychopathology / Marco DEL GIUDICE in Development and Psychopathology, 35-1 (February 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-1 (February 2023) . - p.1-11 Titre : An integrative evolutionary framework for psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : Marco DEL GIUDICE, Auteur ; John D. HALTIGAN, Auteur Article en page(s) : p.1-11 Langues : Anglais (eng) Mots-clés : comorbidity  evolutionary psychiatry  evolutionary psychopathology  heterogeneity  life history strategies  p factor  transdiagnostic models Index. décimale : PER Périodiques Résumé : The field of psychopathology is in a transformative phase, and is witnessing a renewed surge of interest in theoretical models of mental disorders. While many interesting proposals are competing for attention in the literature, they tend to focus narrowly on the proximate level of analysis and lack a broader understanding of biological function. In this paper, we present an integrative framework for mental disorders built on concepts from life history theory, and describe a taxonomy of mental disorders based on its principles, the fast-slow-defense model (FSD). The FSD integrates psychopathology with normative individual differences in personality and behavior, and allows researchers to draw principled distinctions between broad clusters of disorders, as well as identify functional subtypes within current diagnostic categories. Simulation work demonstrates that the model can explain the large-scale structure of comorbidity, including the apparent emergence of a general ''p factor'' of psychopathology. A life history approach also provides novel integrative insights into the role of environmental risk/protective factors and the developmental trajectories of various disorders. En ligne : https://doi.org/10.1017/S0954579421000870 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499 [article] An integrative evolutionary framework for psychopathology [Texte imprimé et/ou numérique] / Marco DEL GIUDICE, Auteur ; John D. HALTIGAN, Auteur . - p.1-11. Langues : Anglais (eng) in Development and Psychopathology > 35-1 (February 2023) . - p.1-11 Mots-clés : comorbidity  evolutionary psychiatry  evolutionary psychopathology  heterogeneity  life history strategies  p factor  transdiagnostic models Index. décimale : PER Périodiques Résumé : The field of psychopathology is in a transformative phase, and is witnessing a renewed surge of interest in theoretical models of mental disorders. While many interesting proposals are competing for attention in the literature, they tend to focus narrowly on the proximate level of analysis and lack a broader understanding of biological function. In this paper, we present an integrative framework for mental disorders built on concepts from life history theory, and describe a taxonomy of mental disorders based on its principles, the fast-slow-defense model (FSD). The FSD integrates psychopathology with normative individual differences in personality and behavior, and allows researchers to draw principled distinctions between broad clusters of disorders, as well as identify functional subtypes within current diagnostic categories. Simulation work demonstrates that the model can explain the large-scale structure of comorbidity, including the apparent emergence of a general ''p factor'' of psychopathology. A life history approach also provides novel integrative insights into the role of environmental risk/protective factors and the developmental trajectories of various disorders. En ligne : https://doi.org/10.1017/S0954579421000870 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499

Beyond allostatic load: Rethinking the role of stress in regulating human development / Bruce J. ELLIS in Development and Psychopathology, 26-1 (February 2014)  

Public ISBD [article]  inDevelopment and Psychopathology > 26-1 (February 2014) . - p.1-20 Titre : Beyond allostatic load: Rethinking the role of stress in regulating human development Type de document : Texte imprimé et/ou numérique Auteurs : Bruce J. ELLIS, Auteur ; Marco DEL GIUDICE, Auteur Article en page(s) : p.1-20 Langues : Français (fre) Index. décimale : PER Périodiques Résumé : How do exposures to stress affect biobehavioral development and, through it, psychiatric and biomedical disorder? In the health sciences, the allostatic load model provides a widely accepted answer to this question: stress responses, while essential for survival, have negative long-term effects that promote illness. Thus, the benefits of mounting repeated biological responses to threat are traded off against costs to mental and physical health. The adaptive calibration model, an evolutionary–developmental theory of stress–health relations, extends this logic by conceptualizing these trade-offs as decision nodes in allocation of resources. Each decision node influences the next in a chain of resource allocations that become instantiated in the regulatory parameters of stress response systems. Over development, these parameters filter and embed information about key dimensions of environmental stress and support, mediating the organism's openness to environmental inputs, and function to regulate life history strategies to match those dimensions. Drawing on the adaptive calibration model, we propose that consideration of biological fitness trade-offs, as delineated by life history theory, is needed to more fully explain the complex relations between developmental exposures to stress, stress responsivity, behavioral strategies, and health. We conclude that the adaptive calibration model and allostatic load model are only partially complementary and, in some cases, support different approaches to intervention. In the long run, the field may be better served by a model informed by life history theory that addresses the adaptive role of stress response systems in regulating alternative developmental pathways. En ligne : http://dx.doi.org/10.1017/S0954579413000849 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=224 [article] Beyond allostatic load: Rethinking the role of stress in regulating human development [Texte imprimé et/ou numérique] / Bruce J. ELLIS, Auteur ; Marco DEL GIUDICE, Auteur . - p.1-20. Langues : Français (fre) in Development and Psychopathology > 26-1 (February 2014) . - p.1-20 Index. décimale : PER Périodiques Résumé : How do exposures to stress affect biobehavioral development and, through it, psychiatric and biomedical disorder? In the health sciences, the allostatic load model provides a widely accepted answer to this question: stress responses, while essential for survival, have negative long-term effects that promote illness. Thus, the benefits of mounting repeated biological responses to threat are traded off against costs to mental and physical health. The adaptive calibration model, an evolutionary–developmental theory of stress–health relations, extends this logic by conceptualizing these trade-offs as decision nodes in allocation of resources. Each decision node influences the next in a chain of resource allocations that become instantiated in the regulatory parameters of stress response systems. Over development, these parameters filter and embed information about key dimensions of environmental stress and support, mediating the organism's openness to environmental inputs, and function to regulate life history strategies to match those dimensions. Drawing on the adaptive calibration model, we propose that consideration of biological fitness trade-offs, as delineated by life history theory, is needed to more fully explain the complex relations between developmental exposures to stress, stress responsivity, behavioral strategies, and health. We conclude that the adaptive calibration model and allostatic load model are only partially complementary and, in some cases, support different approaches to intervention. In the long run, the field may be better served by a model informed by life history theory that addresses the adaptive role of stress response systems in regulating alternative developmental pathways. En ligne : http://dx.doi.org/10.1017/S0954579413000849 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=224

Statistical tests of differential susceptibility: Performance, limitations, and improvements / Marco DEL GIUDICE in Development and Psychopathology, 29-4 (October 2017)  

Public ISBD [article]  inDevelopment and Psychopathology > 29-4 (October 2017) . - p.1267-1278 Titre : Statistical tests of differential susceptibility: Performance, limitations, and improvements Type de document : Texte imprimé et/ou numérique Auteurs : Marco DEL GIUDICE, Auteur Article en page(s) : p.1267-1278 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Statistical tests of differential susceptibility have become standard in the empirical literature, and are routinely used to adjudicate between alternative developmental hypotheses. However, their performance and limitations have never been systematically investigated. In this paper I employ Monte Carlo simulations to explore the functioning of three commonly used tests proposed by Roisman et al. (2012). Simulations showed that critical tests of differential susceptibility require considerably larger samples than standard power calculations would suggest. The results also showed that existing criteria for differential susceptibility based on the proportion of interaction index (i.e., values between .40 and .60) are especially likely to produce false negatives and highly sensitive to assumptions about interaction symmetry. As an initial response to these problems, I propose a revised test based on a broader window of proportion of interaction index values (between .20 and .80). Additional simulations showed that the revised test outperforms existing tests of differential susceptibility, considerably improving detection with little effect on the rate of false positives. I conclude by noting the limitations of a purely statistical approach to differential susceptibility, and discussing the implications of the present results for the interpretation of published findings and the design of future studies in this area. En ligne : http://dx.doi.org/10.1017/s0954579416001292 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=312 [article] Statistical tests of differential susceptibility: Performance, limitations, and improvements [Texte imprimé et/ou numérique] / Marco DEL GIUDICE, Auteur . - p.1267-1278. Langues : Anglais (eng) in Development and Psychopathology > 29-4 (October 2017) . - p.1267-1278 Index. décimale : PER Périodiques Résumé : Abstract Statistical tests of differential susceptibility have become standard in the empirical literature, and are routinely used to adjudicate between alternative developmental hypotheses. However, their performance and limitations have never been systematically investigated. In this paper I employ Monte Carlo simulations to explore the functioning of three commonly used tests proposed by Roisman et al. (2012). Simulations showed that critical tests of differential susceptibility require considerably larger samples than standard power calculations would suggest. The results also showed that existing criteria for differential susceptibility based on the proportion of interaction index (i.e., values between .40 and .60) are especially likely to produce false negatives and highly sensitive to assumptions about interaction symmetry. As an initial response to these problems, I propose a revised test based on a broader window of proportion of interaction index values (between .20 and .80). Additional simulations showed that the revised test outperforms existing tests of differential susceptibility, considerably improving detection with little effect on the rate of false positives. I conclude by noting the limitations of a purely statistical approach to differential susceptibility, and discussing the implications of the present results for the interpretation of published findings and the design of future studies in this area. En ligne : http://dx.doi.org/10.1017/s0954579416001292 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=312

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