Developmental regression and autism reported to the Vaccine Adverse Event Reporting System / Emily Jane WOO in Autism, 11-4 (July 2007)  

Public ISBD [article]  inAutism > 11-4 (July 2007) . - p.301-310 Titre : Developmental regression and autism reported to the Vaccine Adverse Event Reporting System Type de document : Texte imprimé et/ou numérique Auteurs : Emily Jane WOO, Auteur ; Rebecca LANDA, Auteur ; Robert BALL, Auteur ; Andrew W. ZIMMERMAN, Auteur ; M. MILES BRAUN, Auteur ; VAERS WORKING GROUP, CENTER FOR BIOLOGICS EVALUATION AND RESEARCH, FOOD AND DRUG ADMINISTRATION, MARYLAND, USA, Auteur Année de publication : 2007 Article en page(s) : p.301-310 Langues : Anglais (eng) Mots-clés : Adverse-event Autism Regression Vaccine Index. décimale : PER Périodiques Résumé : We report demographic and clinical characteristics of children reported to the US Vaccine Adverse Event Reporting System (VAERS) as having autism or another developmental disorder after vaccination. We completed 124 interviews with parents and reviewed medical records for 31 children whose records contained sufficient information to evaluate the child's developmental history. Medical record review indicated that 27 of 31 (87%) children had autism/ASD and 19 (61.3%) had evidence of developmental regression (loss of social, language, or motor skills). The proportion of VAERS cases of autism with regression was greater than that reported in population-based studies, based on the subset of VAERS cases with medical record confirmation. This difference may reflect preferential reporting to VAERS of autism with regression. In other respects, the children in this study appear to be similar to other children with autism. Further research might determine whether the pathogenesis of autism with developmental regression differs from that of autism without regression. En ligne : http://dx.doi.org/10.1177/1362361307078126 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=158 [article] Developmental regression and autism reported to the Vaccine Adverse Event Reporting System [Texte imprimé et/ou numérique] / Emily Jane WOO, Auteur ; Rebecca LANDA, Auteur ; Robert BALL, Auteur ; Andrew W. ZIMMERMAN, Auteur ; M. MILES BRAUN, Auteur ; VAERS WORKING GROUP, CENTER FOR BIOLOGICS EVALUATION AND RESEARCH, FOOD AND DRUG ADMINISTRATION, MARYLAND, USA, Auteur . - 2007 . - p.301-310. Langues : Anglais (eng) in Autism > 11-4 (July 2007) . - p.301-310 Mots-clés : Adverse-event Autism Regression Vaccine Index. décimale : PER Périodiques Résumé : We report demographic and clinical characteristics of children reported to the US Vaccine Adverse Event Reporting System (VAERS) as having autism or another developmental disorder after vaccination. We completed 124 interviews with parents and reviewed medical records for 31 children whose records contained sufficient information to evaluate the child's developmental history. Medical record review indicated that 27 of 31 (87%) children had autism/ASD and 19 (61.3%) had evidence of developmental regression (loss of social, language, or motor skills). The proportion of VAERS cases of autism with regression was greater than that reported in population-based studies, based on the subset of VAERS cases with medical record confirmation. This difference may reflect preferential reporting to VAERS of autism with regression. In other respects, the children in this study appear to be similar to other children with autism. Further research might determine whether the pathogenesis of autism with developmental regression differs from that of autism without regression. En ligne : http://dx.doi.org/10.1177/1362361307078126 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=158

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