Associations of Down Syndrome with Autism Spectrum Disorder and Attention Deficit/ Hyperactivity Disorder Among Children and Adolescents / Xin WANG in Journal of Autism and Developmental Disorders, 56-10 (October 2026)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 56-10 (October 2026) . - p. 4001-4009 Titre : Associations of Down Syndrome with Autism Spectrum Disorder and Attention Deficit/ Hyperactivity Disorder Among Children and Adolescents Type de document : texte imprimé Auteurs : Xin WANG, Auteur ; Chunhua WANG, Auteur ; Lizi LIN, Auteur ; Wei BAO, Auteur ; Buyun LIU, Auteur ; Baihua LIN, Auteur ; Lijie ZHANG, Auteur ; Guifeng XU, Auteur Article en page(s) : p. 4001-4009 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Children with Down syndrome (DS) are more likely to be diagnosed with co-existing conditions, such as autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). However, the correlation has not been fully delineated to date. Our study aimed to examine the associations of DS with ASD and ADHD in children and adolescents using a national population-based database. In this cross-sectional study, we included a total of 214,300 children aged 3–17 years from the National Health Interview Survey. Physician-diagnosed DS, ASD and ADHD were reported during an in-person household interview. Logistic regression with survey sampling weights was used to estimate the odds ratios (ORs) of ASD and ADHD, along with 95% confidence intervals (CIs). Among the 214,300 children, 329 were identified as having DS. Among those, 21 children were diagnosed with ASD, 48 with ADHD, and 6 exhibited co-existing ASD and ADHD. After adjusting for demographic factors, compared to those without DS, the ORs of ASD, ADHD and the co-occurrence of ASD and ADHD in children with DS were 5.40 (95% CI: 3.04–9.59), 1.72 (95% CI: 1.17–2.53), and 3.45(95% CI:1.29–9.20), respectively. Stratified analysis revealed that significant associations of DS with ASD and ADHD were detected for both male and female, but an interaction effect was only observed between sex and ASD (P < 0.001). Our study confirmed that children with DS are more likely to have comorbidities of ASD and ADHD than the general population, and these comorbidities may vary by sex. En ligne : https://doi.org/10.1007/s10803-025-06834-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=593 [article] Associations of Down Syndrome with Autism Spectrum Disorder and Attention Deficit/ Hyperactivity Disorder Among Children and Adolescents [texte imprimé] / Xin WANG, Auteur ; Chunhua WANG, Auteur ; Lizi LIN, Auteur ; Wei BAO, Auteur ; Buyun LIU, Auteur ; Baihua LIN, Auteur ; Lijie ZHANG, Auteur ; Guifeng XU, Auteur . - p. 4001-4009. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 56-10 (October 2026) . - p. 4001-4009 Index. décimale : PER Périodiques Résumé : Children with Down syndrome (DS) are more likely to be diagnosed with co-existing conditions, such as autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). However, the correlation has not been fully delineated to date. Our study aimed to examine the associations of DS with ASD and ADHD in children and adolescents using a national population-based database. In this cross-sectional study, we included a total of 214,300 children aged 3–17 years from the National Health Interview Survey. Physician-diagnosed DS, ASD and ADHD were reported during an in-person household interview. Logistic regression with survey sampling weights was used to estimate the odds ratios (ORs) of ASD and ADHD, along with 95% confidence intervals (CIs). Among the 214,300 children, 329 were identified as having DS. Among those, 21 children were diagnosed with ASD, 48 with ADHD, and 6 exhibited co-existing ASD and ADHD. After adjusting for demographic factors, compared to those without DS, the ORs of ASD, ADHD and the co-occurrence of ASD and ADHD in children with DS were 5.40 (95% CI: 3.04–9.59), 1.72 (95% CI: 1.17–2.53), and 3.45(95% CI:1.29–9.20), respectively. Stratified analysis revealed that significant associations of DS with ASD and ADHD were detected for both male and female, but an interaction effect was only observed between sex and ASD (P < 0.001). Our study confirmed that children with DS are more likely to have comorbidities of ASD and ADHD than the general population, and these comorbidities may vary by sex. En ligne : https://doi.org/10.1007/s10803-025-06834-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=593

Maternal Diabetes and the Risk of Autism Spectrum Disorders in the Offspring: A Systematic Review and Meta-Analysis / Guifeng XU in Journal of Autism and Developmental Disorders, 44-4 (April 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-4 (April 2014) . - p.766-775 Titre : Maternal Diabetes and the Risk of Autism Spectrum Disorders in the Offspring: A Systematic Review and Meta-Analysis Type de document : texte imprimé Auteurs : Guifeng XU, Auteur ; Jin JING, Auteur ; Katherine BOWERS, Auteur ; Buyun LIU, Auteur ; Wei BAO, Auteur Année de publication : 2014 Article en page(s) : p.766-775 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Diabetes  Pregnancy Index. décimale : PER Périodiques Résumé : We performed a systematic literature search regarding maternal diabetes before and during pregnancy and the risk of autism spectrum disorders (ASD) in the offspring. Of the 178 potentially relevant articles, 12 articles including three cohort studies and nine case–control studies were included in the meta-analysis. Both the meta-analyses of cohort studies and case–control studies showed significant associations. The pooled relative risk and 95 % confidence interval (CI) among cohort studies was 1.48 (1.25–1.75, p 0.001). For case–control studies, the pooled odds ratio and 95 % CI was 1.72 (1.24–2.41, p = 0.001). No indication of significant heterogeneity across studies or publication bias was observed. In conclusion, maternal diabetes was significantly associated with a greater risk of ASD in the offspring. En ligne : http://dx.doi.org/10.1007/s10803-013-1928-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=228 [article] Maternal Diabetes and the Risk of Autism Spectrum Disorders in the Offspring: A Systematic Review and Meta-Analysis [texte imprimé] / Guifeng XU, Auteur ; Jin JING, Auteur ; Katherine BOWERS, Auteur ; Buyun LIU, Auteur ; Wei BAO, Auteur . - 2014 . - p.766-775. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-4 (April 2014) . - p.766-775 Mots-clés : Autism spectrum disorders  Diabetes  Pregnancy Index. décimale : PER Périodiques Résumé : We performed a systematic literature search regarding maternal diabetes before and during pregnancy and the risk of autism spectrum disorders (ASD) in the offspring. Of the 178 potentially relevant articles, 12 articles including three cohort studies and nine case–control studies were included in the meta-analysis. Both the meta-analyses of cohort studies and case–control studies showed significant associations. The pooled relative risk and 95 % confidence interval (CI) among cohort studies was 1.48 (1.25–1.75, p 0.001). For case–control studies, the pooled odds ratio and 95 % CI was 1.72 (1.24–2.41, p = 0.001). No indication of significant heterogeneity across studies or publication bias was observed. In conclusion, maternal diabetes was significantly associated with a greater risk of ASD in the offspring. En ligne : http://dx.doi.org/10.1007/s10803-013-1928-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=228

Prevalence of Autism Spectrum Disorder Among Children and Adolescents in the United States from 2021 to 2022 / Xiaofang YAN in Journal of Autism and Developmental Disorders, 56-6 (June 2026)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 56-6 (June 2026) . - p.2469-2475 Titre : Prevalence of Autism Spectrum Disorder Among Children and Adolescents in the United States from 2021 to 2022 Type de document : texte imprimé Auteurs : Xiaofang YAN, Auteur ; Yanmei LI, Auteur ; Qishan LI, Auteur ; Qian LI, Auteur ; Guifeng XU, Auteur ; Jinhua LU, Auteur ; Wenhan YANG, Auteur Article en page(s) : p.2469-2475 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The prevalence of autism spectrum disorder (ASD) among children and adolescents seem to be high in countries around the world, and it’s worth understanding the latest prevalence and trends of ASD in children and adolescents. The purpose of this study was to examine the latest prevalence and decade trend of ASD among individuals aged 3–17 years in the United States. En ligne : https://doi.org/10.1007/s10803-024-06390-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=588 [article] Prevalence of Autism Spectrum Disorder Among Children and Adolescents in the United States from 2021 to 2022 [texte imprimé] / Xiaofang YAN, Auteur ; Yanmei LI, Auteur ; Qishan LI, Auteur ; Qian LI, Auteur ; Guifeng XU, Auteur ; Jinhua LU, Auteur ; Wenhan YANG, Auteur . - p.2469-2475. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 56-6 (June 2026) . - p.2469-2475 Index. décimale : PER Périodiques Résumé : The prevalence of autism spectrum disorder (ASD) among children and adolescents seem to be high in countries around the world, and it’s worth understanding the latest prevalence and trends of ASD in children and adolescents. The purpose of this study was to examine the latest prevalence and decade trend of ASD among individuals aged 3–17 years in the United States. En ligne : https://doi.org/10.1007/s10803-024-06390-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=588

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