Effects of methylphenidate on working memory components: influence of measurement / Anne-Claude BEDARD in Journal of Child Psychology and Psychiatry, 48-9 (September 2007)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 48-9 (September 2007) . - p.872–880 Titre : Effects of methylphenidate on working memory components: influence of measurement Type de document : Texte imprimé et/ou numérique Auteurs : Anne-Claude BEDARD, Auteur ; Rosemary TANNOCK, Auteur ; Umesh JAIN, Auteur ; Sheilah HOGG-JOHNSON, Auteur Année de publication : 2007 Article en page(s) : p.872–880 Langues : Anglais (eng) Mots-clés : Attention-deficit-hyperactivity-disorder methylphenidate working-memory children adolescents clinical-trial Index. décimale : PER Périodiques Résumé : Background: To investigate the effects of methylphenidate (MPH) on components of working memory (WM) in attention-deficit hyperactivity disorder (ADHD) and determine the responsiveness of WM measures to MPH. Methods: Participants were a clinical sample of 50 children and adolescents with ADHD, aged 6 to 16 years old, who participated in an acute randomized, double-blind, placebo-controlled, crossover trial with single challenges of three MPH doses. Four components of WM were investigated, which varied in processing demands (storage versus manipulation of information) and modality (auditory-verbal; visual-spatial), each of which was indexed by a minimum of two separate measures. Results: MPH improved the ability to store visual-spatial information irrespective of instrument used, but had no effects on the storage of auditory-verbal information. By contrast, MPH enhanced the ability to manipulate both auditory-verbal and visual-spatial information, although effects were instrument specific in both cases. Conclusions: MPH effects on WM are selective: they vary as a function of WM component and measurement. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01760.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=163 [article] Effects of methylphenidate on working memory components: influence of measurement [Texte imprimé et/ou numérique] / Anne-Claude BEDARD, Auteur ; Rosemary TANNOCK, Auteur ; Umesh JAIN, Auteur ; Sheilah HOGG-JOHNSON, Auteur . - 2007 . - p.872–880. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 48-9 (September 2007) . - p.872–880 Mots-clés : Attention-deficit-hyperactivity-disorder methylphenidate working-memory children adolescents clinical-trial Index. décimale : PER Périodiques Résumé : Background: To investigate the effects of methylphenidate (MPH) on components of working memory (WM) in attention-deficit hyperactivity disorder (ADHD) and determine the responsiveness of WM measures to MPH. Methods: Participants were a clinical sample of 50 children and adolescents with ADHD, aged 6 to 16 years old, who participated in an acute randomized, double-blind, placebo-controlled, crossover trial with single challenges of three MPH doses. Four components of WM were investigated, which varied in processing demands (storage versus manipulation of information) and modality (auditory-verbal; visual-spatial), each of which was indexed by a minimum of two separate measures. Results: MPH improved the ability to store visual-spatial information irrespective of instrument used, but had no effects on the storage of auditory-verbal information. By contrast, MPH enhanced the ability to manipulate both auditory-verbal and visual-spatial information, although effects were instrument specific in both cases. Conclusions: MPH effects on WM are selective: they vary as a function of WM component and measurement. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01760.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=163

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