Interpersonal violence moderates sustained-transient threat co-activation in the vmPFC and amygdala in a community sample of youth / Jane E. JOSEPH ; Zachary W. ADAMS ; Kathleen I. CRUM ; Christopher T. SEGE ; Lisa M. MCTEAGUE ; Greg HAJCAK ; Colleen A. HALLIDAY ; Carla Kmett DANIELSON in Development and Psychopathology, 37-4 (October 2025)  

Public ISBD [article]  inDevelopment and Psychopathology > 37-4 (October 2025) . - p.2151-2160 Titre : Interpersonal violence moderates sustained-transient threat co-activation in the vmPFC and amygdala in a community sample of youth Type de document : Texte imprimé et/ou numérique Auteurs : Jane E. JOSEPH, Auteur ; Zachary W. ADAMS, Auteur ; Kathleen I. CRUM, Auteur ; Christopher T. SEGE, Auteur ; Lisa M. MCTEAGUE, Auteur ; Greg HAJCAK, Auteur ; Colleen A. HALLIDAY, Auteur ; Carla Kmett DANIELSON, Auteur Article en page(s) : p.2151-2160 Langues : Anglais (eng) Mots-clés : Childhood adversity  RdoC  threat processing Index. décimale : PER Périodiques Résumé : The increased risk for psychopathology associated with interpersonal violence exposure (IPV, e.g., physical abuse, sexual assault) is partially mediated by neurobiological alterations in threat-related processes. Evidence supports parsing neural circuitry related to transient and sustained threat, as they appear to be separable processes with distinct neurobiological underpinnings. Although childhood is a sensitive period for neurodevelopment, most prior work has been conducted in adult samples. Further, it is unknown how IPV exposure may impact transient-sustained threat neural interactions. The current study tested the moderating role of IPV exposure on sustained vmPFC-transient amygdala co-activation during an fMRI task during which threat and neutral cues were predictably or unpredictably presented. Analyses were conducted in a sample of 212 community-recruited youth (M/SDage = 11.77/2.44 years old; 51.9% male; 56.1% White/Caucasian). IPV-exposed youth evidenced a positive sustained vmPFC-transient amygdala co-activation, while youth with no IPV exposure did not show this association. Consistent with theoretical models, effects were specific to unpredictable, negative trials and to exposure to IPV (i.e., unrelated to non-IPV traumatic experiences). Although preliminary, these findings provide novel insight into how childhood IPV exposure may alter neural circuity involved in specific facets of threat processing. En ligne : https://dx.doi.org/10.1017/S0954579424001743 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=567 [article] Interpersonal violence moderates sustained-transient threat co-activation in the vmPFC and amygdala in a community sample of youth [Texte imprimé et/ou numérique] / Jane E. JOSEPH, Auteur ; Zachary W. ADAMS, Auteur ; Kathleen I. CRUM, Auteur ; Christopher T. SEGE, Auteur ; Lisa M. MCTEAGUE, Auteur ; Greg HAJCAK, Auteur ; Colleen A. HALLIDAY, Auteur ; Carla Kmett DANIELSON, Auteur . - p.2151-2160. Langues : Anglais (eng) in Development and Psychopathology > 37-4 (October 2025) . - p.2151-2160 Mots-clés : Childhood adversity  RdoC  threat processing Index. décimale : PER Périodiques Résumé : The increased risk for psychopathology associated with interpersonal violence exposure (IPV, e.g., physical abuse, sexual assault) is partially mediated by neurobiological alterations in threat-related processes. Evidence supports parsing neural circuitry related to transient and sustained threat, as they appear to be separable processes with distinct neurobiological underpinnings. Although childhood is a sensitive period for neurodevelopment, most prior work has been conducted in adult samples. Further, it is unknown how IPV exposure may impact transient-sustained threat neural interactions. The current study tested the moderating role of IPV exposure on sustained vmPFC-transient amygdala co-activation during an fMRI task during which threat and neutral cues were predictably or unpredictably presented. Analyses were conducted in a sample of 212 community-recruited youth (M/SDage = 11.77/2.44 years old; 51.9% male; 56.1% White/Caucasian). IPV-exposed youth evidenced a positive sustained vmPFC-transient amygdala co-activation, while youth with no IPV exposure did not show this association. Consistent with theoretical models, effects were specific to unpredictable, negative trials and to exposure to IPV (i.e., unrelated to non-IPV traumatic experiences). Although preliminary, these findings provide novel insight into how childhood IPV exposure may alter neural circuity involved in specific facets of threat processing. En ligne : https://dx.doi.org/10.1017/S0954579424001743 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=567

Prevalence and predictors of PTSD and depression among adolescent victims of the Spring 2011 tornado outbreak / Zachary W. ADAMS in Journal of Child Psychology and Psychiatry, 55-9 (September 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-9 (September 2014) . - p.1047-1055 Titre : Prevalence and predictors of PTSD and depression among adolescent victims of the Spring 2011 tornado outbreak Type de document : Texte imprimé et/ou numérique Auteurs : Zachary W. ADAMS, Auteur ; Jennifer A. SUMNER, Auteur ; Carla Kmett DANIELSON, Auteur ; Jenna L. MCCAULEY, Auteur ; Heidi S. RESNICK, Auteur ; Kirstin GROS, Auteur ; Lisa A. PAUL, Auteur ; Kyleen E. WELSH, Auteur ; Kenneth J. RUGGIERO, Auteur Article en page(s) : p.1047-1055 Langues : Anglais (eng) Mots-clés : Disaster  adolescents  PTSD  depression  tornadoes Index. décimale : PER Périodiques Résumé : Background Relatively few studies have examined prevalence and predictors of posttraumatic stress disorder (PTSD) or major depressive episode (MDE) in disaster-affected adolescents. Fewer still have administered diagnostic measures or studied samples exposed to tornadoes, a common type of disaster. Further, methodologic problems limit the generalizability of previous findings. This study addressed prevalence estimates and risk factors for PTSD and MDE among adolescents exposed to the Spring 2011 tornado outbreak in Alabama and Joplin, Missouri. Methods A large (N = 2000), population-based sample of adolescents and caregivers, recruited randomly from tornado-affected communities, participated in structured telephone interviews. PTSD and MDE prevalence were estimated for the overall sample, by gender, and by age. Hierarchical logistic regression was used to identify risk factors for PTSD and MDE. Results Overall, 6.7% of adolescents met diagnostic criteria for PTSD and 7.5% of adolescents met diagnostic criteria for MDE since the tornado. Girls were significantly more likely than boys to meet diagnostic criteria for MDE, and older adolescents were more likely than younger adolescents to report MDE since the tornado. Female gender, prior trauma exposure, and an injured family member were associated with greater risk for PTSD and MDE. Specific incident characteristics (loss of services, concern about others’ safety) were associated with greater PTSD risk; prior disaster exposure was associated with lower MDE risk. Conclusions However, most adolescents were resilient following tornado exposure, roughly 1 in 15 developed PTSD, 1 in 13 developed MDE, and many more endorsed subclinical mental health problems. Information regarding specific risk factors can guide early screening, prevention, and intervention efforts in disaster-affected communities. En ligne : http://dx.doi.org/10.1111/jcpp.12220 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238 [article] Prevalence and predictors of PTSD and depression among adolescent victims of the Spring 2011 tornado outbreak [Texte imprimé et/ou numérique] / Zachary W. ADAMS, Auteur ; Jennifer A. SUMNER, Auteur ; Carla Kmett DANIELSON, Auteur ; Jenna L. MCCAULEY, Auteur ; Heidi S. RESNICK, Auteur ; Kirstin GROS, Auteur ; Lisa A. PAUL, Auteur ; Kyleen E. WELSH, Auteur ; Kenneth J. RUGGIERO, Auteur . - p.1047-1055. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-9 (September 2014) . - p.1047-1055 Mots-clés : Disaster  adolescents  PTSD  depression  tornadoes Index. décimale : PER Périodiques Résumé : Background Relatively few studies have examined prevalence and predictors of posttraumatic stress disorder (PTSD) or major depressive episode (MDE) in disaster-affected adolescents. Fewer still have administered diagnostic measures or studied samples exposed to tornadoes, a common type of disaster. Further, methodologic problems limit the generalizability of previous findings. This study addressed prevalence estimates and risk factors for PTSD and MDE among adolescents exposed to the Spring 2011 tornado outbreak in Alabama and Joplin, Missouri. Methods A large (N = 2000), population-based sample of adolescents and caregivers, recruited randomly from tornado-affected communities, participated in structured telephone interviews. PTSD and MDE prevalence were estimated for the overall sample, by gender, and by age. Hierarchical logistic regression was used to identify risk factors for PTSD and MDE. Results Overall, 6.7% of adolescents met diagnostic criteria for PTSD and 7.5% of adolescents met diagnostic criteria for MDE since the tornado. Girls were significantly more likely than boys to meet diagnostic criteria for MDE, and older adolescents were more likely than younger adolescents to report MDE since the tornado. Female gender, prior trauma exposure, and an injured family member were associated with greater risk for PTSD and MDE. Specific incident characteristics (loss of services, concern about others’ safety) were associated with greater PTSD risk; prior disaster exposure was associated with lower MDE risk. Conclusions However, most adolescents were resilient following tornado exposure, roughly 1 in 15 developed PTSD, 1 in 13 developed MDE, and many more endorsed subclinical mental health problems. Information regarding specific risk factors can guide early screening, prevention, and intervention efforts in disaster-affected communities. En ligne : http://dx.doi.org/10.1111/jcpp.12220 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238

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