[article]
| Titre : |
Increased Risk for Substance Use-Related Problems in Autism Spectrum Disorders: A Population-Based Cohort Study |
| Type de document : |
texte imprimé |
| Auteurs : |
Agnieszka BUTWICKA, Auteur ; Niklas LANGSTROM, Auteur ; Henrik LARSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Eva SERLACHIUS, Auteur ; Catarina ALMQVIST, Auteur ; Louise FRISÉN, Auteur ; Paul LICHTENSTEIN, Auteur |
| Article en page(s) : |
p.80-89 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Autism spectrum disorder Addiction ADHD Intellectual disability ICD |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Despite limited and ambiguous empirical data, substance use-related problems have been assumed to be rare among patients with autism spectrum disorders (ASD). Using Swedish population-based registers we identified 26,986 individuals diagnosed with ASD during 1973–2009, and their 96,557 non-ASD relatives. ASD, without diagnosed comorbidity of attention deficit hyperactivity disorder (ADHD) or intellectual disability, was related to a doubled risk of substance use-related problems. The risk of substance use-related problems was the highest among individuals with ASD and ADHD. Further, risks of substance use-related problems were increased among full siblings of ASD probands, half-siblings and parents. We conclude that ASD is a risk factor for substance use-related problems. The elevated risks among relatives of probands with ASD suggest shared familial (genetic and/or shared environmental) liability. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-016-2914-2 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 |
in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.80-89
[article] Increased Risk for Substance Use-Related Problems in Autism Spectrum Disorders: A Population-Based Cohort Study [texte imprimé] / Agnieszka BUTWICKA, Auteur ; Niklas LANGSTROM, Auteur ; Henrik LARSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Eva SERLACHIUS, Auteur ; Catarina ALMQVIST, Auteur ; Louise FRISÉN, Auteur ; Paul LICHTENSTEIN, Auteur . - p.80-89. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.80-89
| Mots-clés : |
Autism spectrum disorder Addiction ADHD Intellectual disability ICD |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Despite limited and ambiguous empirical data, substance use-related problems have been assumed to be rare among patients with autism spectrum disorders (ASD). Using Swedish population-based registers we identified 26,986 individuals diagnosed with ASD during 1973–2009, and their 96,557 non-ASD relatives. ASD, without diagnosed comorbidity of attention deficit hyperactivity disorder (ADHD) or intellectual disability, was related to a doubled risk of substance use-related problems. The risk of substance use-related problems was the highest among individuals with ASD and ADHD. Further, risks of substance use-related problems were increased among full siblings of ASD probands, half-siblings and parents. We conclude that ASD is a risk factor for substance use-related problems. The elevated risks among relatives of probands with ASD suggest shared familial (genetic and/or shared environmental) liability. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-016-2914-2 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 |
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