[article] 
inJournal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.80-89

Titre :	Increased Risk for Substance Use-Related Problems in Autism Spectrum Disorders: A Population-Based Cohort Study
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Agnieszka BUTWICKA, Auteur ; Niklas LANGSTROM, Auteur ; Henrik LARSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Eva SERLACHIUS, Auteur ; Catarina ALMQVIST, Auteur ; Louise FRISÉN, Auteur ; Paul LICHTENSTEIN, Auteur
Article en page(s) :	p.80-89
Langues :	Anglais (eng)
Mots-clés :	Autism spectrum disorder  Addiction  ADHD  Intellectual disability  ICD
Index. décimale :	PER Périodiques
Résumé :	Despite limited and ambiguous empirical data, substance use-related problems have been assumed to be rare among patients with autism spectrum disorders (ASD). Using Swedish population-based registers we identified 26,986 individuals diagnosed with ASD during 1973–2009, and their 96,557 non-ASD relatives. ASD, without diagnosed comorbidity of attention deficit hyperactivity disorder (ADHD) or intellectual disability, was related to a doubled risk of substance use-related problems. The risk of substance use-related problems was the highest among individuals with ASD and ADHD. Further, risks of substance use-related problems were increased among full siblings of ASD probands, half-siblings and parents. We conclude that ASD is a risk factor for substance use-related problems. The elevated risks among relatives of probands with ASD suggest shared familial (genetic and/or shared environmental) liability.
En ligne :	http://dx.doi.org/10.1007/s10803-016-2914-2
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298

[article] Increased Risk for Substance Use-Related Problems in Autism Spectrum Disorders: A Population-Based Cohort Study [Texte imprimé et/ou numérique] / Agnieszka BUTWICKA, Auteur ; Niklas LANGSTROM, Auteur ; Henrik LARSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Eva SERLACHIUS, Auteur ; Catarina ALMQVIST, Auteur ; Louise FRISÉN, Auteur ; Paul LICHTENSTEIN, Auteur . - p.80-89.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.80-89

Mots-clés :	Autism spectrum disorder  Addiction  ADHD  Intellectual disability  ICD
Index. décimale :	PER Périodiques
Résumé :	Despite limited and ambiguous empirical data, substance use-related problems have been assumed to be rare among patients with autism spectrum disorders (ASD). Using Swedish population-based registers we identified 26,986 individuals diagnosed with ASD during 1973–2009, and their 96,557 non-ASD relatives. ASD, without diagnosed comorbidity of attention deficit hyperactivity disorder (ADHD) or intellectual disability, was related to a doubled risk of substance use-related problems. The risk of substance use-related problems was the highest among individuals with ASD and ADHD. Further, risks of substance use-related problems were increased among full siblings of ASD probands, half-siblings and parents. We conclude that ASD is a risk factor for substance use-related problems. The elevated risks among relatives of probands with ASD suggest shared familial (genetic and/or shared environmental) liability.
En ligne :	http://dx.doi.org/10.1007/s10803-016-2914-2
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298