[article] 
inJournal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1436-1452

Titre :	Electrophysiological Endophenotypes and the Error-Related Negativity (ERN) in Autism Spectrum Disorder: A Family Study
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Ann CLAWSON, Auteur ; Mikle SOUTH, Auteur ; Scott A. BALDWIN, Auteur ; Michael J. LARSON, Auteur
Article en page(s) :	p.1436-1452
Langues :	Anglais (eng)
Mots-clés :	Autism spectrum disorder  Error-related negativity  Cognitive control  Endophenotype
Index. décimale :	PER Périodiques
Résumé :	We examined the error-related negativity (ERN) as an endophenotype of ASD by comparing the ERN in families of ASD probands to control families. We hypothesized that ASD probands and families would display reduced-amplitude ERN relative to controls. Participants included 148 individuals within 39 families consisting of a mother, father, sibling, and proband. Robust ANOVAs revealed non-significant differences in ERN amplitude and behavioral performance among ASD probands relative to control youth. In subsequent multiple regression analyses group and kinship (proband, sibling, mother, father) did not significantly predict ?ERN (error minus correct ERN) or behavioral performance. Results do not provide evidence for the ERN as an endophenotype of ASD. Future research is needed to examine state- or trait-related factors influencing ERN amplitudes in ASD.
En ligne :	http://dx.doi.org/10.1007/s10803-017-3066-8
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305

[article] Electrophysiological Endophenotypes and the Error-Related Negativity (ERN) in Autism Spectrum Disorder: A Family Study [Texte imprimé et/ou numérique] / Ann CLAWSON, Auteur ; Mikle SOUTH, Auteur ; Scott A. BALDWIN, Auteur ; Michael J. LARSON, Auteur . - p.1436-1452.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1436-1452

Mots-clés :	Autism spectrum disorder  Error-related negativity  Cognitive control  Endophenotype
Index. décimale :	PER Périodiques
Résumé :	We examined the error-related negativity (ERN) as an endophenotype of ASD by comparing the ERN in families of ASD probands to control families. We hypothesized that ASD probands and families would display reduced-amplitude ERN relative to controls. Participants included 148 individuals within 39 families consisting of a mother, father, sibling, and proband. Robust ANOVAs revealed non-significant differences in ERN amplitude and behavioral performance among ASD probands relative to control youth. In subsequent multiple regression analyses group and kinship (proband, sibling, mother, father) did not significantly predict ?ERN (error minus correct ERN) or behavioral performance. Results do not provide evidence for the ERN as an endophenotype of ASD. Future research is needed to examine state- or trait-related factors influencing ERN amplitudes in ASD.
En ligne :	http://dx.doi.org/10.1007/s10803-017-3066-8
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305