Autistic spectrum disorder, attention deficit hyperactivity disorder, and psychiatric comorbidities: A nationwide study / Mu-Hong CHEN in Research in Autism Spectrum Disorders, 10 (February 2015)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 10 (February 2015) . - p.1-6 Titre : Autistic spectrum disorder, attention deficit hyperactivity disorder, and psychiatric comorbidities: A nationwide study Type de document : texte imprimé Auteurs : Mu-Hong CHEN, Auteur ; Han-Ting WEI, Auteur ; Li-Chi CHEN, Auteur ; Tung-Ping SU, Auteur ; Ya-Mei BAI, Auteur ; Ju-Wei HSU, Auteur ; Kai-Lin HUANG, Auteur ; Wen-Han CHANG, Auteur ; Tzeng-Ji CHEN, Auteur ; Ying-Sheue CHEN, Auteur Article en page(s) : p.1-6 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Attention deficit hyperactivity disorder  Psychiatric comorbidities Index. décimale : PER Périodiques Résumé : Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are both frequently comorbid with other psychiatric disorders, but the comorbid effect of ASD and ADHD relative to the comorbid risk of other psychiatric disorders is still unknown. Using the Taiwan National Health Insurance Research Database, 725 patients with ASD-alone, 5694 with ADHD-alone, 466 with ASD + ADHD, and 27,540 (1:4) age-/gender-matched controls were enrolled in our study. The risk of psychiatric comorbidities was investigated. The ADHD + ASD group had the greatest risk of developing schizophrenia (hazard ratio [HR]: 95.89; HR: 13.73; HR: 174.61), bipolar disorder (HR: 74.93; HR: 19.42; HR: 36.71), depressive disorder (HR: 17.66; HR: 12.29; HR: 9.05), anxiety disorder (HR: 49.49; HR: 50.92; HR: 14.12), disruptive behavior disorder (HR: 113.89; HR: 93.87; HR: 26.50), and tic disorder (HR: 8.95; HR: 7.46; HR: 4.87) compared to the ADHD-alone, ASD-alone, and control groups. Patients with ADHD + ASD were associated with the greatest risk of having comorbid bipolar disorder, depressive disorder, anxiety disorder, disruptive behavior disorder, and tic disorder. The diagnoses of ASD and ADHD preceded the diagnoses of other psychiatric comorbidities. A comprehensive interview scrutinizing the psychiatric comorbidities would be suggested when encountering and following patients with both ASD and ADHD in clinical practice. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.10.014 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 [article] Autistic spectrum disorder, attention deficit hyperactivity disorder, and psychiatric comorbidities: A nationwide study [texte imprimé] / Mu-Hong CHEN, Auteur ; Han-Ting WEI, Auteur ; Li-Chi CHEN, Auteur ; Tung-Ping SU, Auteur ; Ya-Mei BAI, Auteur ; Ju-Wei HSU, Auteur ; Kai-Lin HUANG, Auteur ; Wen-Han CHANG, Auteur ; Tzeng-Ji CHEN, Auteur ; Ying-Sheue CHEN, Auteur . - p.1-6. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 10 (February 2015) . - p.1-6 Mots-clés : Autism spectrum disorder  Attention deficit hyperactivity disorder  Psychiatric comorbidities Index. décimale : PER Périodiques Résumé : Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are both frequently comorbid with other psychiatric disorders, but the comorbid effect of ASD and ADHD relative to the comorbid risk of other psychiatric disorders is still unknown. Using the Taiwan National Health Insurance Research Database, 725 patients with ASD-alone, 5694 with ADHD-alone, 466 with ASD + ADHD, and 27,540 (1:4) age-/gender-matched controls were enrolled in our study. The risk of psychiatric comorbidities was investigated. The ADHD + ASD group had the greatest risk of developing schizophrenia (hazard ratio [HR]: 95.89; HR: 13.73; HR: 174.61), bipolar disorder (HR: 74.93; HR: 19.42; HR: 36.71), depressive disorder (HR: 17.66; HR: 12.29; HR: 9.05), anxiety disorder (HR: 49.49; HR: 50.92; HR: 14.12), disruptive behavior disorder (HR: 113.89; HR: 93.87; HR: 26.50), and tic disorder (HR: 8.95; HR: 7.46; HR: 4.87) compared to the ADHD-alone, ASD-alone, and control groups. Patients with ADHD + ASD were associated with the greatest risk of having comorbid bipolar disorder, depressive disorder, anxiety disorder, disruptive behavior disorder, and tic disorder. The diagnoses of ASD and ADHD preceded the diagnoses of other psychiatric comorbidities. A comprehensive interview scrutinizing the psychiatric comorbidities would be suggested when encountering and following patients with both ASD and ADHD in clinical practice. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.10.014 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260

Effect of Parental Severe Mental Disorders on the Timing of Autism Diagnosis: A Family Linkage Study / Yu TUAN in Journal of Autism and Developmental Disorders, 55-12 (December 2025)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 55-12 (December 2025) . - p.4304-4311 Titre : Effect of Parental Severe Mental Disorders on the Timing of Autism Diagnosis: A Family Linkage Study Type de document : texte imprimé Auteurs : Yu TUAN, Auteur ; Li-Chi CHEN, Auteur ; I. Chun CHEN, Auteur ; Shih-Jen TSAI, Auteur ; Tzeng-Ji CHEN, Auteur ; Mu-Hong CHEN, Auteur Article en page(s) : p.4304-4311 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The mean diagnosis age of autism was about 5 years in Taiwan. Whether the delayed diagnosis of autism (≥ 6 years) was associated with parental severe mental disorders remained unknown. The parents of 22,859 autistic individuals and 228,590 age- and sex-matched nonautistic individuals were assessed for the presence of severe mental disorders (schizophrenia, bipolar disorder, major depressive disorder, alcohol use disorder, and substance use disorder). The timing of autism diagnosis was classified into three age categories: < 6 years, 6-11 years, and ≥ 12 years. Logistic regression models were used to examine associations between parental severe mental disorders and these age categories of autism diagnosis. Parental schizophrenia and substance use disorders were associated with the delayed diagnosis of autism, both diagnosis at ≥ 12 years (odds ratio [OR]: 2.14; 1.57) and at 6-11 years (1.87; 1.38). Parental bipolar disorder and major depressive disorder were also associated with the delayed diagnosis of autism, especially diagnosis at 6-11 years (OR 1.98; 1.86). Our findings underscore the need for clinicians to monitor the neurodevelopmental conditions of offspring born to parents with severe mental disorders during the early stages of their life. En ligne : https://doi.org/10.1007/s10803-024-06518-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572 [article] Effect of Parental Severe Mental Disorders on the Timing of Autism Diagnosis: A Family Linkage Study [texte imprimé] / Yu TUAN, Auteur ; Li-Chi CHEN, Auteur ; I. Chun CHEN, Auteur ; Shih-Jen TSAI, Auteur ; Tzeng-Ji CHEN, Auteur ; Mu-Hong CHEN, Auteur . - p.4304-4311. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 55-12 (December 2025) . - p.4304-4311 Index. décimale : PER Périodiques Résumé : The mean diagnosis age of autism was about 5 years in Taiwan. Whether the delayed diagnosis of autism (≥ 6 years) was associated with parental severe mental disorders remained unknown. The parents of 22,859 autistic individuals and 228,590 age- and sex-matched nonautistic individuals were assessed for the presence of severe mental disorders (schizophrenia, bipolar disorder, major depressive disorder, alcohol use disorder, and substance use disorder). The timing of autism diagnosis was classified into three age categories: < 6 years, 6-11 years, and ≥ 12 years. Logistic regression models were used to examine associations between parental severe mental disorders and these age categories of autism diagnosis. Parental schizophrenia and substance use disorders were associated with the delayed diagnosis of autism, both diagnosis at ≥ 12 years (odds ratio [OR]: 2.14; 1.57) and at 6-11 years (1.87; 1.38). Parental bipolar disorder and major depressive disorder were also associated with the delayed diagnosis of autism, especially diagnosis at 6-11 years (OR 1.98; 1.86). Our findings underscore the need for clinicians to monitor the neurodevelopmental conditions of offspring born to parents with severe mental disorders during the early stages of their life. En ligne : https://doi.org/10.1007/s10803-024-06518-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572

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