[article] 
inDevelopment and Psychopathology > 29-3 (August 2017) . - p.837-843

Titre :	Extremely low birth weight babies grown up: Gene–environment interaction predicts internalizing problems in the third and fourth decades of life
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Ayelet LAHAT, Auteur ; Ryan J. VAN LIESHOUT, Auteur ; Karen J. MATHEWSON, Auteur ; James MACKILLOP, Auteur ; Saroj SAIGAL, Auteur ; Katherine M. MORRISON, Auteur ; Michael H. BOYLE, Auteur ; Louis A. SCHMIDT, Auteur
Article en page(s) :	p.837-843
Langues :	Anglais (eng)
Index. décimale :	PER Périodiques
Résumé :	Abstract Extremely low birth weight (ELBW; 5-HTTLPR). We followed the oldest longitudinal cohort of ELBW survivors to adulthood. Participants provided buccal cells and reported on internalizing problems, using the Young Adult Self-Report when they were in their mid-20s (ELBW/SGA, N = 28; ELBW/AGA, N = 60; NBW, N = 81) and mid-30s (ELBW/SGA, N = 27; ELBW/AGA, N = 58; NBW, N = 76). The findings indicate that ELBW/SGAs carrying the 5-HTTLPR short allele reported increased internalizing problems, particularly depression, during the third and fourth decades of life. This is the first known report on gene–environment interactions predicting psychopathology among ELBW survivors. Our findings elucidate putative neurobiological pathways that underlie risk for psychopathology.
En ligne :	http://dx.doi.org/10.1017/s0954579416000511
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=311

[article] Extremely low birth weight babies grown up: Gene–environment interaction predicts internalizing problems in the third and fourth decades of life [Texte imprimé et/ou numérique] / Ayelet LAHAT, Auteur ; Ryan J. VAN LIESHOUT, Auteur ; Karen J. MATHEWSON, Auteur ; James MACKILLOP, Auteur ; Saroj SAIGAL, Auteur ; Katherine M. MORRISON, Auteur ; Michael H. BOYLE, Auteur ; Louis A. SCHMIDT, Auteur . - p.837-843.
Langues : Anglais (eng)
in Development and Psychopathology > 29-3 (August 2017) . - p.837-843

Index. décimale :	PER Périodiques
Résumé :	Abstract Extremely low birth weight (ELBW; 5-HTTLPR). We followed the oldest longitudinal cohort of ELBW survivors to adulthood. Participants provided buccal cells and reported on internalizing problems, using the Young Adult Self-Report when they were in their mid-20s (ELBW/SGA, N = 28; ELBW/AGA, N = 60; NBW, N = 81) and mid-30s (ELBW/SGA, N = 27; ELBW/AGA, N = 58; NBW, N = 76). The findings indicate that ELBW/SGAs carrying the 5-HTTLPR short allele reported increased internalizing problems, particularly depression, during the third and fourth decades of life. This is the first known report on gene–environment interactions predicting psychopathology among ELBW survivors. Our findings elucidate putative neurobiological pathways that underlie risk for psychopathology.
En ligne :	http://dx.doi.org/10.1017/s0954579416000511
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=311