Annual Research Review: Digital health interventions for children and young people with mental health problems – a systematic and meta-review / Chris HOLLIS in Journal of Child Psychology and Psychiatry, 58-4 (April 2017)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 58-4 (April 2017) . - p.474-503 Titre : Annual Research Review: Digital health interventions for children and young people with mental health problems – a systematic and meta-review Type de document : Texte imprimé et/ou numérique Auteurs : Chris HOLLIS, Auteur ; Caroline J. FALCONER, Auteur ; Jennifer L. MARTIN, Auteur ; Craig WHITTINGTON, Auteur ; Sarah STOCKTON, Auteur ; Cris GLAZEBROOK, Auteur ; E. Bethan DAVIES, Auteur Article en page(s) : p.474-503 Langues : Anglais (eng) Mots-clés : Digital health  mental health  eHealth  methodology  randomised controlled trials  prevention Index. décimale : PER Périodiques Résumé : Background Digital health interventions (DHIs), including computer-assisted therapy, smartphone apps and wearable technologies, are heralded as having enormous potential to improve uptake and accessibility, efficiency, clinical effectiveness and personalisation of mental health interventions. It is generally assumed that DHIs will be preferred by children and young people (CYP) given their ubiquitous digital activity. However, it remains uncertain whether: DHIs for CYP are clinically and cost-effective, CYP prefer DHIs to traditional services, DHIs widen access and how they should be evaluated and adopted by mental health services. This review evaluates the evidence-base for DHIs and considers the key research questions and approaches to evaluation and implementation. Methods We conducted a meta-review of scoping, narrative, systematic or meta-analytical reviews investigating the effectiveness of DHIs for mental health problems in CYP. We also updated a systematic review of randomised controlled trials (RCTs) of DHIs for CYP published in the last 3 years. Results Twenty-one reviews were included in the meta-review. The findings provide some support for the clinical benefit of DHIs, particularly computerised cognitive behavioural therapy (cCBT), for depression and anxiety in adolescents and young adults. The systematic review identified 30 new RCTs evaluating DHIs for attention deficit/hyperactivity disorder (ADHD), autism, anxiety, depression, psychosis, eating disorders and PTSD. The benefits of DHIs in managing ADHD, autism, psychosis and eating disorders are uncertain, and evidence is lacking regarding the cost-effectiveness of DHIs. Conclusions Key methodological limitations make it difficult to draw definitive conclusions from existing clinical trials of DHIs. Issues include variable uptake and engagement with DHIs, lack of an agreed typology/taxonomy for DHIs, small sample sizes, lack of blinded outcome assessment, combining different comparators, short-term follow-up and poor specification of the level of human support. Research and practice recommendations are presented that address the key research questions and methodological issues for the evaluation and clinical implementation of DHIs for CYP. En ligne : http://dx.doi.org/10.1111/jcpp.12663 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305 [article] Annual Research Review: Digital health interventions for children and young people with mental health problems – a systematic and meta-review [Texte imprimé et/ou numérique] / Chris HOLLIS, Auteur ; Caroline J. FALCONER, Auteur ; Jennifer L. MARTIN, Auteur ; Craig WHITTINGTON, Auteur ; Sarah STOCKTON, Auteur ; Cris GLAZEBROOK, Auteur ; E. Bethan DAVIES, Auteur . - p.474-503. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 58-4 (April 2017) . - p.474-503 Mots-clés : Digital health  mental health  eHealth  methodology  randomised controlled trials  prevention Index. décimale : PER Périodiques Résumé : Background Digital health interventions (DHIs), including computer-assisted therapy, smartphone apps and wearable technologies, are heralded as having enormous potential to improve uptake and accessibility, efficiency, clinical effectiveness and personalisation of mental health interventions. It is generally assumed that DHIs will be preferred by children and young people (CYP) given their ubiquitous digital activity. However, it remains uncertain whether: DHIs for CYP are clinically and cost-effective, CYP prefer DHIs to traditional services, DHIs widen access and how they should be evaluated and adopted by mental health services. This review evaluates the evidence-base for DHIs and considers the key research questions and approaches to evaluation and implementation. Methods We conducted a meta-review of scoping, narrative, systematic or meta-analytical reviews investigating the effectiveness of DHIs for mental health problems in CYP. We also updated a systematic review of randomised controlled trials (RCTs) of DHIs for CYP published in the last 3 years. Results Twenty-one reviews were included in the meta-review. The findings provide some support for the clinical benefit of DHIs, particularly computerised cognitive behavioural therapy (cCBT), for depression and anxiety in adolescents and young adults. The systematic review identified 30 new RCTs evaluating DHIs for attention deficit/hyperactivity disorder (ADHD), autism, anxiety, depression, psychosis, eating disorders and PTSD. The benefits of DHIs in managing ADHD, autism, psychosis and eating disorders are uncertain, and evidence is lacking regarding the cost-effectiveness of DHIs. Conclusions Key methodological limitations make it difficult to draw definitive conclusions from existing clinical trials of DHIs. Issues include variable uptake and engagement with DHIs, lack of an agreed typology/taxonomy for DHIs, small sample sizes, lack of blinded outcome assessment, combining different comparators, short-term follow-up and poor specification of the level of human support. Research and practice recommendations are presented that address the key research questions and methodological issues for the evaluation and clinical implementation of DHIs for CYP. En ligne : http://dx.doi.org/10.1111/jcpp.12663 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305

Commentary: Let's get digital: a commentary on Halldorsson et al.'s call for more rigorous development and evaluation of immersive digital interventions for children and young people's mental health / E. Bethan DAVIES in Journal of Child Psychology and Psychiatry, 62-5 (May 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-5 (May 2021) . - p.606-609 Titre : Commentary: Let's get digital: a commentary on Halldorsson et al.'s call for more rigorous development and evaluation of immersive digital interventions for children and young people's mental health Type de document : Texte imprimé et/ou numérique Auteurs : E. Bethan DAVIES, Auteur ; Aislinn Dawn BERGIN, Auteur Article en page(s) : p.606-609 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : In the JCPP Annual Research Review for 2021, Halldorsson and colleagues (2021) present a systematic review of applied games and virtual reality interventions for treating mental health problems in children and young people, looking at the effectiveness of interventions upon mental health outcomes but also on the experience of using such interventions. In this commentary, we highlight a number of considerations in understanding what research has been achieved so far, and ideas for what needs to be looked at next in further advancing this field. En ligne : http://dx.doi.org/10.1111/jcpp.13423 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445 [article] Commentary: Let's get digital: a commentary on Halldorsson et al.'s call for more rigorous development and evaluation of immersive digital interventions for children and young people's mental health [Texte imprimé et/ou numérique] / E. Bethan DAVIES, Auteur ; Aislinn Dawn BERGIN, Auteur . - p.606-609. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-5 (May 2021) . - p.606-609 Index. décimale : PER Périodiques Résumé : In the JCPP Annual Research Review for 2021, Halldorsson and colleagues (2021) present a systematic review of applied games and virtual reality interventions for treating mental health problems in children and young people, looking at the effectiveness of interventions upon mental health outcomes but also on the experience of using such interventions. In this commentary, we highlight a number of considerations in understanding what research has been achieved so far, and ideas for what needs to be looked at next in further advancing this field. En ligne : http://dx.doi.org/10.1111/jcpp.13423 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445

Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial / Chris HOLLIS in Journal of Child Psychology and Psychiatry, 64-6 (June 2023)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 64-6 (June 2023) . - p.941-951 Titre : Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial Type de document : Texte imprimé et/ou numérique Auteurs : Chris HOLLIS, Auteur ; Charlotte L. HALL, Auteur ; Kareem KHAN, Auteur ; Rebecca JONES, Auteur ; Louise MARSTON, Auteur ; Marie LE NOVERE, Auteur ; Rachael HUNTER, Auteur ; Per ANDRÉN, Auteur ; Sophie D. BENNETT, Auteur ; Beverley J. BROWN, Auteur ; Liam R. CHAMBERLAIN, Auteur ; E. Bethan DAVIES, Auteur ; Amber EVANS, Auteur ; Natalia KOUZOUPI, Auteur ; Caitlin MCKENZIE, Auteur ; Charlotte SANDERSON, Auteur ; Isobel HEYMAN, Auteur ; Joseph KILGARIFF, Auteur ; Cristine GLAZEBROOK, Auteur ; David MATAIX-COLS, Auteur ; Eva SERLACHIUS, Auteur ; Elizabeth MURRAY, Auteur ; Tara MURPHY, Auteur Article en page(s) : p.941-951 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Little is known about the long-term effectiveness of behavioural therapy for tics. We aimed to assess the long-term clinical and cost-effectiveness of online therapist-supported exposure and response prevention (ERP) therapy for tics 12 and 18 months after treatment initiation. Methods ORBIT (online remote behavioural intervention for tics) was a two-arm (1:1 ratio), superiority, single-blind, multicentre randomised controlled trial comparing online ERP for tics with online psychoeducation. The trial was conducted across two Child and Adolescent Mental Health Services in England. Participants were recruited from these two sites, across other clinics in England, or by self-referral. This study was a naturalistic follow-up of participants at 12- and 18-month postrandomisation. Participants were permitted to use alternative treatments recommended by their clinician. The key outcome was the Yale Global Tic Severity Scale Total Tic Severity Score (YGTSS-TTSS). A full economic evaluation was conducted. Registrations are ISRCTN (ISRCTN70758207); ClinicalTrials.gov (NCT03483493). Results Two hundred and twenty-four participants were enrolled: 112 to ERP and 112 to psychoeducation. The sample was predominately male (177; 79%) and of white ethnicity (195; 87%). The ERP intervention reduced baseline YGTSS-TTSS by 2.64 points (95% CI: ?4.48 to ?0.79) with an effect size of ?0.36 (95% CI: ?0.61 to ?0.11) after 12?months and by 2.01 points (95% CI: ?3.86 to ?0.15) with an effect size of ?0.27 (95% CI -0.52 to ?0.02) after 18?months, compared with psychoeducation. Very few participants (<10%) started new tic treatment during follow-up. The cost difference in ERP compared with psychoeducation was £304.94 (?139.41 to 749.29). At 18?months, the cost per QALY gained was £16,708 for ERP compared with psychoeducation. Conclusions Remotely delivered online ERP is a clinical and cost-effective intervention with durable benefits extending for up to 18?months. This represents an efficient public mental health approach to increase access to behavioural therapy and improve outcomes for tics. En ligne : http://dx.doi.org/https://doi.org/10.1111/jcpp.13756 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504 [article] Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial [Texte imprimé et/ou numérique] / Chris HOLLIS, Auteur ; Charlotte L. HALL, Auteur ; Kareem KHAN, Auteur ; Rebecca JONES, Auteur ; Louise MARSTON, Auteur ; Marie LE NOVERE, Auteur ; Rachael HUNTER, Auteur ; Per ANDRÉN, Auteur ; Sophie D. BENNETT, Auteur ; Beverley J. BROWN, Auteur ; Liam R. CHAMBERLAIN, Auteur ; E. Bethan DAVIES, Auteur ; Amber EVANS, Auteur ; Natalia KOUZOUPI, Auteur ; Caitlin MCKENZIE, Auteur ; Charlotte SANDERSON, Auteur ; Isobel HEYMAN, Auteur ; Joseph KILGARIFF, Auteur ; Cristine GLAZEBROOK, Auteur ; David MATAIX-COLS, Auteur ; Eva SERLACHIUS, Auteur ; Elizabeth MURRAY, Auteur ; Tara MURPHY, Auteur . - p.941-951. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 64-6 (June 2023) . - p.941-951 Index. décimale : PER Périodiques Résumé : Background Little is known about the long-term effectiveness of behavioural therapy for tics. We aimed to assess the long-term clinical and cost-effectiveness of online therapist-supported exposure and response prevention (ERP) therapy for tics 12 and 18 months after treatment initiation. Methods ORBIT (online remote behavioural intervention for tics) was a two-arm (1:1 ratio), superiority, single-blind, multicentre randomised controlled trial comparing online ERP for tics with online psychoeducation. The trial was conducted across two Child and Adolescent Mental Health Services in England. Participants were recruited from these two sites, across other clinics in England, or by self-referral. This study was a naturalistic follow-up of participants at 12- and 18-month postrandomisation. Participants were permitted to use alternative treatments recommended by their clinician. The key outcome was the Yale Global Tic Severity Scale Total Tic Severity Score (YGTSS-TTSS). A full economic evaluation was conducted. Registrations are ISRCTN (ISRCTN70758207); ClinicalTrials.gov (NCT03483493). Results Two hundred and twenty-four participants were enrolled: 112 to ERP and 112 to psychoeducation. The sample was predominately male (177; 79%) and of white ethnicity (195; 87%). The ERP intervention reduced baseline YGTSS-TTSS by 2.64 points (95% CI: ?4.48 to ?0.79) with an effect size of ?0.36 (95% CI: ?0.61 to ?0.11) after 12?months and by 2.01 points (95% CI: ?3.86 to ?0.15) with an effect size of ?0.27 (95% CI -0.52 to ?0.02) after 18?months, compared with psychoeducation. Very few participants (<10%) started new tic treatment during follow-up. The cost difference in ERP compared with psychoeducation was £304.94 (?139.41 to 749.29). At 18?months, the cost per QALY gained was £16,708 for ERP compared with psychoeducation. Conclusions Remotely delivered online ERP is a clinical and cost-effective intervention with durable benefits extending for up to 18?months. This represents an efficient public mental health approach to increase access to behavioural therapy and improve outcomes for tics. En ligne : http://dx.doi.org/https://doi.org/10.1111/jcpp.13756 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504

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