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Auteur Charlotte SANDERSON |
Documents disponibles écrits par cet auteur (2)
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Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial / Chris HOLLIS in Journal of Child Psychology and Psychiatry, 64-6 (June 2023)
[article]
Titre : Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial Type de document : Texte imprimé et/ou numérique Auteurs : Chris HOLLIS, Auteur ; Charlotte L. HALL, Auteur ; Kareem KHAN, Auteur ; Rebecca JONES, Auteur ; Louise MARSTON, Auteur ; Marie LE NOVERE, Auteur ; Rachael HUNTER, Auteur ; Per ANDRÉN, Auteur ; Sophie D. BENNETT, Auteur ; Beverley J. BROWN, Auteur ; Liam R. CHAMBERLAIN, Auteur ; E. Bethan DAVIES, Auteur ; Amber EVANS, Auteur ; Natalia KOUZOUPI, Auteur ; Caitlin MCKENZIE, Auteur ; Charlotte SANDERSON, Auteur ; Isobel HEYMAN, Auteur ; Joseph KILGARIFF, Auteur ; Cristine GLAZEBROOK, Auteur ; David MATAIX-COLS, Auteur ; Eva SERLACHIUS, Auteur ; Elizabeth MURRAY, Auteur ; Tara MURPHY, Auteur Article en page(s) : p.941-951 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Little is known about the long-term effectiveness of behavioural therapy for tics. We aimed to assess the long-term clinical and cost-effectiveness of online therapist-supported exposure and response prevention (ERP) therapy for tics 12 and 18 months after treatment initiation. Methods ORBIT (online remote behavioural intervention for tics) was a two-arm (1:1 ratio), superiority, single-blind, multicentre randomised controlled trial comparing online ERP for tics with online psychoeducation. The trial was conducted across two Child and Adolescent Mental Health Services in England. Participants were recruited from these two sites, across other clinics in England, or by self-referral. This study was a naturalistic follow-up of participants at 12- and 18-month postrandomisation. Participants were permitted to use alternative treatments recommended by their clinician. The key outcome was the Yale Global Tic Severity Scale Total Tic Severity Score (YGTSS-TTSS). A full economic evaluation was conducted. Registrations are ISRCTN (ISRCTN70758207); ClinicalTrials.gov (NCT03483493). Results Two hundred and twenty-four participants were enrolled: 112 to ERP and 112 to psychoeducation. The sample was predominately male (177; 79%) and of white ethnicity (195; 87%). The ERP intervention reduced baseline YGTSS-TTSS by 2.64 points (95% CI: ?4.48 to ?0.79) with an effect size of ?0.36 (95% CI: ?0.61 to ?0.11) after 12?months and by 2.01 points (95% CI: ?3.86 to ?0.15) with an effect size of ?0.27 (95% CI -0.52 to ?0.02) after 18?months, compared with psychoeducation. Very few participants (<10%) started new tic treatment during follow-up. The cost difference in ERP compared with psychoeducation was £304.94 (?139.41 to 749.29). At 18?months, the cost per QALY gained was £16,708 for ERP compared with psychoeducation. Conclusions Remotely delivered online ERP is a clinical and cost-effective intervention with durable benefits extending for up to 18?months. This represents an efficient public mental health approach to increase access to behavioural therapy and improve outcomes for tics. En ligne : http://dx.doi.org/https://doi.org/10.1111/jcpp.13756 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504
in Journal of Child Psychology and Psychiatry > 64-6 (June 2023) . - p.941-951[article] Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial [Texte imprimé et/ou numérique] / Chris HOLLIS, Auteur ; Charlotte L. HALL, Auteur ; Kareem KHAN, Auteur ; Rebecca JONES, Auteur ; Louise MARSTON, Auteur ; Marie LE NOVERE, Auteur ; Rachael HUNTER, Auteur ; Per ANDRÉN, Auteur ; Sophie D. BENNETT, Auteur ; Beverley J. BROWN, Auteur ; Liam R. CHAMBERLAIN, Auteur ; E. Bethan DAVIES, Auteur ; Amber EVANS, Auteur ; Natalia KOUZOUPI, Auteur ; Caitlin MCKENZIE, Auteur ; Charlotte SANDERSON, Auteur ; Isobel HEYMAN, Auteur ; Joseph KILGARIFF, Auteur ; Cristine GLAZEBROOK, Auteur ; David MATAIX-COLS, Auteur ; Eva SERLACHIUS, Auteur ; Elizabeth MURRAY, Auteur ; Tara MURPHY, Auteur . - p.941-951.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 64-6 (June 2023) . - p.941-951
Index. décimale : PER Périodiques Résumé : Background Little is known about the long-term effectiveness of behavioural therapy for tics. We aimed to assess the long-term clinical and cost-effectiveness of online therapist-supported exposure and response prevention (ERP) therapy for tics 12 and 18 months after treatment initiation. Methods ORBIT (online remote behavioural intervention for tics) was a two-arm (1:1 ratio), superiority, single-blind, multicentre randomised controlled trial comparing online ERP for tics with online psychoeducation. The trial was conducted across two Child and Adolescent Mental Health Services in England. Participants were recruited from these two sites, across other clinics in England, or by self-referral. This study was a naturalistic follow-up of participants at 12- and 18-month postrandomisation. Participants were permitted to use alternative treatments recommended by their clinician. The key outcome was the Yale Global Tic Severity Scale Total Tic Severity Score (YGTSS-TTSS). A full economic evaluation was conducted. Registrations are ISRCTN (ISRCTN70758207); ClinicalTrials.gov (NCT03483493). Results Two hundred and twenty-four participants were enrolled: 112 to ERP and 112 to psychoeducation. The sample was predominately male (177; 79%) and of white ethnicity (195; 87%). The ERP intervention reduced baseline YGTSS-TTSS by 2.64 points (95% CI: ?4.48 to ?0.79) with an effect size of ?0.36 (95% CI: ?0.61 to ?0.11) after 12?months and by 2.01 points (95% CI: ?3.86 to ?0.15) with an effect size of ?0.27 (95% CI -0.52 to ?0.02) after 18?months, compared with psychoeducation. Very few participants (<10%) started new tic treatment during follow-up. The cost difference in ERP compared with psychoeducation was £304.94 (?139.41 to 749.29). At 18?months, the cost per QALY gained was £16,708 for ERP compared with psychoeducation. Conclusions Remotely delivered online ERP is a clinical and cost-effective intervention with durable benefits extending for up to 18?months. This represents an efficient public mental health approach to increase access to behavioural therapy and improve outcomes for tics. En ligne : http://dx.doi.org/https://doi.org/10.1111/jcpp.13756 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504 The Specificity of Inhibitory Impairments in Autism and Their Relation to ADHD-Type Symptoms / Charlotte SANDERSON in Journal of Autism and Developmental Disorders, 43-5 (May 2013)
[article]
Titre : The Specificity of Inhibitory Impairments in Autism and Their Relation to ADHD-Type Symptoms Type de document : Texte imprimé et/ou numérique Auteurs : Charlotte SANDERSON, Auteur ; Melissa L. ALLEN, Auteur Article en page(s) : p.1065-1079 Langues : Anglais (eng) Mots-clés : Autism Inhibition ADHD Executive function Index. décimale : PER Périodiques Résumé : Findings on inhibitory control in autism have been inconsistent. This is perhaps a reflection of the different tasks that have been used. Children with autism (CWA) and typically developing controls, matched for verbal and non-verbal mental age, completed three tasks of inhibition, each representing different inhibitory subcomponents: Go/No-Go (delay inhibition), Dog-Pig Stroop (conflict inhibition), and a Flanker task (resistance to distractor inhibition). Behavioural ratings of inattention and hyperactivity/impulsivity were also obtained, as a possible source of heterogeneity in inhibitory ability. CWA were only impaired on the conflict inhibition task, suggesting that inhibitory difficulty is not a core executive deficit in autism. Symptoms of inattention were related to conflict task performance, and thus may be an important predictor of inhibitory heterogeneity. En ligne : http://dx.doi.org/10.1007/s10803-012-1650-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=195
in Journal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1065-1079[article] The Specificity of Inhibitory Impairments in Autism and Their Relation to ADHD-Type Symptoms [Texte imprimé et/ou numérique] / Charlotte SANDERSON, Auteur ; Melissa L. ALLEN, Auteur . - p.1065-1079.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1065-1079
Mots-clés : Autism Inhibition ADHD Executive function Index. décimale : PER Périodiques Résumé : Findings on inhibitory control in autism have been inconsistent. This is perhaps a reflection of the different tasks that have been used. Children with autism (CWA) and typically developing controls, matched for verbal and non-verbal mental age, completed three tasks of inhibition, each representing different inhibitory subcomponents: Go/No-Go (delay inhibition), Dog-Pig Stroop (conflict inhibition), and a Flanker task (resistance to distractor inhibition). Behavioural ratings of inattention and hyperactivity/impulsivity were also obtained, as a possible source of heterogeneity in inhibitory ability. CWA were only impaired on the conflict inhibition task, suggesting that inhibitory difficulty is not a core executive deficit in autism. Symptoms of inattention were related to conflict task performance, and thus may be an important predictor of inhibitory heterogeneity. En ligne : http://dx.doi.org/10.1007/s10803-012-1650-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=195