Acceptability and safety of a probiotic beverage supplementation (Bio-K +) and feasibility of the proposed protocol in children with a diagnosis of autism spectrum disorder / Ghizlane GAOUGAOU in Journal of Neurodevelopmental Disorders, 17 (2025)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 17 (2025) Titre : Acceptability and safety of a probiotic beverage supplementation (Bio-K +) and feasibility of the proposed protocol in children with a diagnosis of autism spectrum disorder Type de document : texte imprimé Auteurs : Ghizlane GAOUGAOU, Auteur ; Riham ZAHRA, Auteur ; Sophia MOREL, Auteur ; Véronique BÉLANGER, Auteur ; Inga Sophia KNOTH, Auteur ; Dominique COUSINEAU, Auteur ; Baudouin Forgeot D'ARC, Auteur ; Kelly GRZYWACZ, Auteur ; Guy ROUSSEAU, Auteur ; Eric DÉZIEL, Auteur ; Roger GODBOUT, Auteur ; Sarah LIPPE, Auteur ; Mathieu MILLETTE, Auteur ; Valérie MARCIL, Auteur Langues : Anglais (eng) Mots-clés : Humans  Autism Spectrum Disorder/diet therapy/complications  Probiotics/administration & dosage/adverse effects/therapeutic use  Male  Child  Female  Child, Preschool  Feasibility Studies  Gastrointestinal Diseases  Sleep Wake Disorders  Dietary Supplements  Beverages  Patient Acceptance of Health Care  Acceptability  Autism spectrum disorders  Autistic symptoms  Children  Feasibility  Gastrointestinal symptoms  Probiotics  Safety  Sleep disorder  by the ethics review board of the CHU Sainte-Justine (#2021–3412). Informed  consent was obtained from all participants and parents involved in the study.  Competing interests: The authors declare no competing interests. Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders defined by stereotyped behavior and challenges in social communication and social interaction. ASD is associated with various comorbidities, including anxiety, gastrointestinal (GI) symptoms and sleep disorders. Evidence supports an association between intestinal dysbiosis and the severity of ASD-related symptoms. Probiotic intake was suggested to restore microbial homeostasis and decrease neurobehavioral, GI and sleep symptoms in individuals diagnosed with autism. METHODS: This study aims to evaluate the acceptability and safety of a Bio-K + probiotics beverage in autistic children aged 4 to 11 years and the feasibility of the proposed research protocol to measure its impact on behaviors and comorbidities. The 30-week study consisted of daily supplementation with Bio-K + probiotics for 14 weeks. Acceptability and safety were monitored throughout the study. Feasibility was assessed by comparing recruitment and completion rates to pre-established thresholds. Preliminary impact of supplementation on behaviors (Autism Treatment Evaluation Checklist (ATEC) score), GI symptoms and sleep disorders was evaluated. RESULTS: Of the 23 children recruited (mean age 6.7 ± 2.2 years, 70% males), 65% had GI problems and 91% had sleep disorders. Probiotic supplementation was accepted by all participants and no product-related adverse event was reported. Feasibility rates exceeded pre-established thresholds for almost all study outcomes including recruitment rate, compliance, electroencephalography, actigraphy and completion of questionnaires. Preliminary data suggest an improvement in behaviors associated with autism assessed with the total ATEC score, and in GI symptoms and sleep disorders. CONCLUSION: This study demonstrates probiotic beverage acceptability and safety and protocol feasibility in autistic children. To further support our data, a double-blinded placebo-controlled study is needed to determine its efficacy. En ligne : https://dx.doi.org/10.1186/s11689-025-09617-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576 [article] Acceptability and safety of a probiotic beverage supplementation (Bio-K +) and feasibility of the proposed protocol in children with a diagnosis of autism spectrum disorder [texte imprimé] / Ghizlane GAOUGAOU, Auteur ; Riham ZAHRA, Auteur ; Sophia MOREL, Auteur ; Véronique BÉLANGER, Auteur ; Inga Sophia KNOTH, Auteur ; Dominique COUSINEAU, Auteur ; Baudouin Forgeot D'ARC, Auteur ; Kelly GRZYWACZ, Auteur ; Guy ROUSSEAU, Auteur ; Eric DÉZIEL, Auteur ; Roger GODBOUT, Auteur ; Sarah LIPPE, Auteur ; Mathieu MILLETTE, Auteur ; Valérie MARCIL, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 17 (2025) Mots-clés : Humans  Autism Spectrum Disorder/diet therapy/complications  Probiotics/administration & dosage/adverse effects/therapeutic use  Male  Child  Female  Child, Preschool  Feasibility Studies  Gastrointestinal Diseases  Sleep Wake Disorders  Dietary Supplements  Beverages  Patient Acceptance of Health Care  Acceptability  Autism spectrum disorders  Autistic symptoms  Children  Feasibility  Gastrointestinal symptoms  Probiotics  Safety  Sleep disorder  by the ethics review board of the CHU Sainte-Justine (#2021–3412). Informed  consent was obtained from all participants and parents involved in the study.  Competing interests: The authors declare no competing interests. Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders defined by stereotyped behavior and challenges in social communication and social interaction. ASD is associated with various comorbidities, including anxiety, gastrointestinal (GI) symptoms and sleep disorders. Evidence supports an association between intestinal dysbiosis and the severity of ASD-related symptoms. Probiotic intake was suggested to restore microbial homeostasis and decrease neurobehavioral, GI and sleep symptoms in individuals diagnosed with autism. METHODS: This study aims to evaluate the acceptability and safety of a Bio-K + probiotics beverage in autistic children aged 4 to 11 years and the feasibility of the proposed research protocol to measure its impact on behaviors and comorbidities. The 30-week study consisted of daily supplementation with Bio-K + probiotics for 14 weeks. Acceptability and safety were monitored throughout the study. Feasibility was assessed by comparing recruitment and completion rates to pre-established thresholds. Preliminary impact of supplementation on behaviors (Autism Treatment Evaluation Checklist (ATEC) score), GI symptoms and sleep disorders was evaluated. RESULTS: Of the 23 children recruited (mean age 6.7 ± 2.2 years, 70% males), 65% had GI problems and 91% had sleep disorders. Probiotic supplementation was accepted by all participants and no product-related adverse event was reported. Feasibility rates exceeded pre-established thresholds for almost all study outcomes including recruitment rate, compliance, electroencephalography, actigraphy and completion of questionnaires. Preliminary data suggest an improvement in behaviors associated with autism assessed with the total ATEC score, and in GI symptoms and sleep disorders. CONCLUSION: This study demonstrates probiotic beverage acceptability and safety and protocol feasibility in autistic children. To further support our data, a double-blinded placebo-controlled study is needed to determine its efficacy. En ligne : https://dx.doi.org/10.1186/s11689-025-09617-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576

Brief Report: Biological Sound Processing in Children with Autistic Spectrum Disorder / Melissa LORTIE in Journal of Autism and Developmental Disorders, 47-6 (June 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-6 (June 2017) . - p.1904-1909 Titre : Brief Report: Biological Sound Processing in Children with Autistic Spectrum Disorder Type de document : texte imprimé Auteurs : Melissa LORTIE, Auteur ; Léa PROULX-BEGIN, Auteur ; Dave SAINT-AMOUR, Auteur ; Dominique COUSINEAU, Auteur ; Hugo THEORET, Auteur ; Jean-François LEPAGE, Auteur Article en page(s) : p.1904-1909 Langues : Anglais (eng) Mots-clés : Social impairments  Event related potentials  EEG  Biological actions  Auditory  Attention  Novelty detection  MMN  P3 Index. décimale : PER Périodiques Résumé : There is debate whether social impairments in autism spectrum disorder (ASD) are truly domain-specific, or if they reflect generalized deficits in lower-level cognitive processes. To solve this issue, we used auditory-evoked EEG responses to assess novelty detection (MMN component) and involuntary attentional orientation (P3 component) induced by socially-relevant, human-produced, biological sounds and acoustically-matched control stimuli in children with ASD and controls. Results show that early sensory and novelty processing of biological stimuli are preserved in ASD, but that automatic attentional orientation for biological sounds is markedly altered. These results support the notion that at least some cognitive processes of ASD are specifically altered when it comes to processing social stimuli. En ligne : http://dx.doi.org/10.1007/s10803-017-3093-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=308 [article] Brief Report: Biological Sound Processing in Children with Autistic Spectrum Disorder [texte imprimé] / Melissa LORTIE, Auteur ; Léa PROULX-BEGIN, Auteur ; Dave SAINT-AMOUR, Auteur ; Dominique COUSINEAU, Auteur ; Hugo THEORET, Auteur ; Jean-François LEPAGE, Auteur . - p.1904-1909. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-6 (June 2017) . - p.1904-1909 Mots-clés : Social impairments  Event related potentials  EEG  Biological actions  Auditory  Attention  Novelty detection  MMN  P3 Index. décimale : PER Périodiques Résumé : There is debate whether social impairments in autism spectrum disorder (ASD) are truly domain-specific, or if they reflect generalized deficits in lower-level cognitive processes. To solve this issue, we used auditory-evoked EEG responses to assess novelty detection (MMN component) and involuntary attentional orientation (P3 component) induced by socially-relevant, human-produced, biological sounds and acoustically-matched control stimuli in children with ASD and controls. Results show that early sensory and novelty processing of biological stimuli are preserved in ASD, but that automatic attentional orientation for biological sounds is markedly altered. These results support the notion that at least some cognitive processes of ASD are specifically altered when it comes to processing social stimuli. En ligne : http://dx.doi.org/10.1007/s10803-017-3093-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=308

Diagnostic and Therapeutic Misconception: Parental Expectations and Perspectives Regarding Genetic Testing for Developmental Disorders / Isabelle TREMBLAY in Journal of Autism and Developmental Disorders, 49-1 (January 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.363-375 Titre : Diagnostic and Therapeutic Misconception: Parental Expectations and Perspectives Regarding Genetic Testing for Developmental Disorders Type de document : texte imprimé Auteurs : Isabelle TREMBLAY, Auteur ; Steffany GRONDIN, Auteur ; Anne-Marie LABERGE, Auteur ; Dominique COUSINEAU, Auteur ; Lionel CARMANT, Auteur ; Anita ROWAN, Auteur ; Annie JANVIER, Auteur Article en page(s) : p.363-375 Langues : Anglais (eng) Mots-clés : Array comparative genomic hybridization (aCGH)  Autism spectrum disorder  Chromosomal microarray (CMA) testing  Genetic testing  Global developmental delay  Misconception Index. décimale : PER Périodiques Résumé : Parents' understanding/expectations regarding genetic testing for children with developmental disorders were explored. Within a month of testing, interviews were conducted with 57 parents. Many (74%) could not recall the nature of testing. Parents expected genetic testing to have positive impacts for the child (93%) and the family (98%), mainly to find the etiology and/or an intervention. Many parents (40%) reported not knowing their child's clinical diagnosis. They expected genetic testing would establish the diagnosis. Parents anticipated potential negative impacts of testing for children (78%) and families (87%), mainly finding another illness or not finding potential interventions. Abnormal results explaining the disorder were found in 9% of children. In summary, genetic results for developmental disorders are unlikely to meet parental expectations. En ligne : http://dx.doi.org/10.1007/s10803-018-3768-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=377 [article] Diagnostic and Therapeutic Misconception: Parental Expectations and Perspectives Regarding Genetic Testing for Developmental Disorders [texte imprimé] / Isabelle TREMBLAY, Auteur ; Steffany GRONDIN, Auteur ; Anne-Marie LABERGE, Auteur ; Dominique COUSINEAU, Auteur ; Lionel CARMANT, Auteur ; Anita ROWAN, Auteur ; Annie JANVIER, Auteur . - p.363-375. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.363-375 Mots-clés : Array comparative genomic hybridization (aCGH)  Autism spectrum disorder  Chromosomal microarray (CMA) testing  Genetic testing  Global developmental delay  Misconception Index. décimale : PER Périodiques Résumé : Parents' understanding/expectations regarding genetic testing for children with developmental disorders were explored. Within a month of testing, interviews were conducted with 57 parents. Many (74%) could not recall the nature of testing. Parents expected genetic testing to have positive impacts for the child (93%) and the family (98%), mainly to find the etiology and/or an intervention. Many parents (40%) reported not knowing their child's clinical diagnosis. They expected genetic testing would establish the diagnosis. Parents anticipated potential negative impacts of testing for children (78%) and families (87%), mainly finding another illness or not finding potential interventions. Abnormal results explaining the disorder were found in 9% of children. In summary, genetic results for developmental disorders are unlikely to meet parental expectations. En ligne : http://dx.doi.org/10.1007/s10803-018-3768-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=377

Troubles mentaux chez les enfants et les adolescents / Leïla BEN AMOR

Public ISBD Titre : Troubles mentaux chez les enfants et les adolescents : Prévenir, repérer tôt, intervenir Type de document : texte imprimé Auteurs : Leïla BEN AMOR, Auteur ; Yvon L'ABBE, Auteur ; Dominique COUSINEAU, Auteur ; Philippe LAGEIX, Préfacier, etc. Editeur : Montréal [Canada] : Editions du CHU Sainte-Justine Année de publication : 2017 Importance : 380 p. Format : 17,0 cm × 25,0 cm × 2,5 cm ISBN/ISSN/EAN : 978-2-89619-807-8 Note générale : Bibliogr., Glossaire Langues : Français (fre) Mots-clés : Trouble du neurodéveloppement Index. décimale : TRO-F TRO-F - Autres Troubles Résumé : Parce qu'ils s'installent progressivement - et souvent de façon insidieuse -, les troubles mentaux sont plus difficiles à diagnostiquer à un jeune âge. L'objectif fondamental de cet ouvrage est de rendre compte de l'état actuel des connaissances scientifiques sur le sujet afin d'appuyer les meilleures pratiques cliniques et de favoriser le développement harmonieux des enfants et des adolescents. En s'appuyant sur la classification du DSM-5, ce livre décrit les principaux troubles mentaux chez les jeunes en insistant sur les attitudes aidantes à adopter. Il spécifie aussi les approches et programmes les plus efficaces et suggère des ressources à consulter pour chacun des troubles répertoriés. Il privilégie les programmes de prévention, d'interventions sociales individuelles en santé mentale et de psychothérapies basées sur les données probantes, s'inscrivant ainsi dans les orientations de l'American Psychological Association et de l'Institut national d'excellence en santé et en services sociaux. Abondamment documentée, cette référence répond aux besoins de tous les intervenants en santé mentale qui travaillent auprès des jeunes : médecins, professionnels de la santé et de l'éducation et gestionnaires oeuvrant au sein de ces deux réseaux. [Résumé d'Auteur/Editeur] Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=380 Troubles mentaux chez les enfants et les adolescents : Prévenir, repérer tôt, intervenir [texte imprimé] / Leïla BEN AMOR, Auteur ; Yvon L'ABBE, Auteur ; Dominique COUSINEAU, Auteur ; Philippe LAGEIX, Préfacier, etc. . - Montréal [Canada] : Editions du CHU Sainte-Justine, 2017 . - 380 p. ; 17,0 cm × 25,0 cm × 2,5 cm. ISBN : 978-2-89619-807-8 Bibliogr., Glossaire Langues : Français (fre) Mots-clés : Trouble du neurodéveloppement Index. décimale : TRO-F TRO-F - Autres Troubles Résumé : Parce qu'ils s'installent progressivement - et souvent de façon insidieuse -, les troubles mentaux sont plus difficiles à diagnostiquer à un jeune âge. L'objectif fondamental de cet ouvrage est de rendre compte de l'état actuel des connaissances scientifiques sur le sujet afin d'appuyer les meilleures pratiques cliniques et de favoriser le développement harmonieux des enfants et des adolescents. En s'appuyant sur la classification du DSM-5, ce livre décrit les principaux troubles mentaux chez les jeunes en insistant sur les attitudes aidantes à adopter. Il spécifie aussi les approches et programmes les plus efficaces et suggère des ressources à consulter pour chacun des troubles répertoriés. Il privilégie les programmes de prévention, d'interventions sociales individuelles en santé mentale et de psychothérapies basées sur les données probantes, s'inscrivant ainsi dans les orientations de l'American Psychological Association et de l'Institut national d'excellence en santé et en services sociaux. Abondamment documentée, cette référence répond aux besoins de tous les intervenants en santé mentale qui travaillent auprès des jeunes : médecins, professionnels de la santé et de l'éducation et gestionnaires oeuvrant au sein de ces deux réseaux. [Résumé d'Auteur/Editeur] Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=380

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
DOC0004711	TRO-F BEN	Livre	Centre d'Information et de Documentation du CRA Rhône-Alpes	TRO - Autres Troubles	Disponible

Les abonnés qui ont emprunté ce document ont également emprunté :

Les Troubles du comportement	O'REGAN, Fintan
Pragmatique et pathologies	DARDIER, Virginie
Développement cognitif et communicatif du jeune enfant	NADER-GROSBOIS, Nathalie
Applied Behavior Analysis for Children with Autism Spectrum Disorders	MATSON, Johnny L.
L'Asperger au travail	SIMONE, Rudy
L’autisme expliqué par un autiste	MOULAS, Thibaud

---

1 (1 - 4 / 4) Par page : 25 50 100 200