[article]
Titre : |
Oncogenes Involved in the Etiology of Autism |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
A.J. RUSSO, Auteur |
Article en page(s) : |
p.11-13 |
Langues : |
Anglais (eng) |
Mots-clés : |
epidermal growth factor receptor (EGFR) epidermal growth factor (EGF) hepatocyte growth factor receptor (HGFR) cMet hepatocyte growth factor (HGF) autism |
Index. décimale : |
PER Périodiques |
Résumé : |
Epidermal growth factor receptor (EGFR) gene and Hepatocyte Growth Factor Receptor gene, c-Met, are proto-oncogenes which code for cell-surface tyrosine kinase receptors, EGFR and hepatocyte growth factor (HGF), respectively. These membrane receptors are stimulated by ligands, epidermal growth factor (EGF) and hepatocyte growth factor (HGF), and then, through a cascade of reactions, regulate several important cell events such as growth, motility, and morphogenesis. This editorial presents a cursory look at the evidence that these proto-oncogenes, and their products, are involved in the etiology of neurobehavioral disorders, such as autism. |
En ligne : |
https://dx.doi.org/10.4137/AUI.S14280 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409 |
in Autism Insights > (February 2014) . - p.11-13
[article] Oncogenes Involved in the Etiology of Autism [Texte imprimé et/ou numérique] / A.J. RUSSO, Auteur . - p.11-13. Langues : Anglais ( eng) in Autism Insights > (February 2014) . - p.11-13
Mots-clés : |
epidermal growth factor receptor (EGFR) epidermal growth factor (EGF) hepatocyte growth factor receptor (HGFR) cMet hepatocyte growth factor (HGF) autism |
Index. décimale : |
PER Périodiques |
Résumé : |
Epidermal growth factor receptor (EGFR) gene and Hepatocyte Growth Factor Receptor gene, c-Met, are proto-oncogenes which code for cell-surface tyrosine kinase receptors, EGFR and hepatocyte growth factor (HGF), respectively. These membrane receptors are stimulated by ligands, epidermal growth factor (EGF) and hepatocyte growth factor (HGF), and then, through a cascade of reactions, regulate several important cell events such as growth, motility, and morphogenesis. This editorial presents a cursory look at the evidence that these proto-oncogenes, and their products, are involved in the etiology of neurobehavioral disorders, such as autism. |
En ligne : |
https://dx.doi.org/10.4137/AUI.S14280 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409 |
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