Are There Enhanced MBP Autoantibodies in Autism? / Jane E. LIBBEY in Journal of Autism and Developmental Disorders, 38-2 (February 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-2 (February 2008) . - p.324-332 Titre : Are There Enhanced MBP Autoantibodies in Autism? Type de document : Texte imprimé et/ou numérique Auteurs : Jane E. LIBBEY, Auteur ; William M. MCMAHON, Auteur ; Janet E. LAINHART, Auteur ; Hilary H. COON, Auteur ; Nikki J. KIRKMAN, Auteur ; Thayne L. SWEETEN, Auteur ; Judith N. MILLER, Auteur ; Edward K. STEVENSON, Auteur ; Robert S. FUJINAMI, Auteur Année de publication : 2008 Article en page(s) : p.324-332 Langues : Anglais (eng) Mots-clés : Autism Tourette-syndrome Autoantibody Myelin-basic-protein Immunoglobulin Index. décimale : PER Périodiques Résumé : Autoantibodies to central nervous system antigens, such as myelin basic protein (MBP), may play a role in autism. We measured autoantibody titers to MBP in children with autism, both classic onset and regressive onset forms, controls (healthy age- and gender-matched) and individuals with Tourette syndrome via enzyme-linked immunosorbent assays. We found a significant difference in autoantibody titers to MBP, not accounted for by age or medication, between Tourette and classic autism (both significantly lower) when compared to regressive autism, but not when compared to controls. Autoantibody responses against MBP are unlikely to play a pathogenic role in autism. En ligne : http://dx.doi.org/10.1007/s10803-007-0400-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=318 [article] Are There Enhanced MBP Autoantibodies in Autism? [Texte imprimé et/ou numérique] / Jane E. LIBBEY, Auteur ; William M. MCMAHON, Auteur ; Janet E. LAINHART, Auteur ; Hilary H. COON, Auteur ; Nikki J. KIRKMAN, Auteur ; Thayne L. SWEETEN, Auteur ; Judith N. MILLER, Auteur ; Edward K. STEVENSON, Auteur ; Robert S. FUJINAMI, Auteur . - 2008 . - p.324-332. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-2 (February 2008) . - p.324-332 Mots-clés : Autism Tourette-syndrome Autoantibody Myelin-basic-protein Immunoglobulin Index. décimale : PER Périodiques Résumé : Autoantibodies to central nervous system antigens, such as myelin basic protein (MBP), may play a role in autism. We measured autoantibody titers to MBP in children with autism, both classic onset and regressive onset forms, controls (healthy age- and gender-matched) and individuals with Tourette syndrome via enzyme-linked immunosorbent assays. We found a significant difference in autoantibody titers to MBP, not accounted for by age or medication, between Tourette and classic autism (both significantly lower) when compared to regressive autism, but not when compared to controls. Autoantibody responses against MBP are unlikely to play a pathogenic role in autism. En ligne : http://dx.doi.org/10.1007/s10803-007-0400-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=318

How Relevant are GFAP Autoantibodies in Autism and Tourette Syndrome? / Nikki J. KIRKMAN in Journal of Autism and Developmental Disorders, 38-2 (February 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-2 (February 2008) . - p.333-341 Titre : How Relevant are GFAP Autoantibodies in Autism and Tourette Syndrome? Type de document : Texte imprimé et/ou numérique Auteurs : Nikki J. KIRKMAN, Auteur ; William M. MCMAHON, Auteur ; Janet E. LAINHART, Auteur ; Jane E. LIBBEY, Auteur ; Hilary H. COON, Auteur ; Thayne L. SWEETEN, Auteur ; Judith N. MILLER, Auteur ; Edward K. STEVENSON, Auteur ; Robert S. FUJINAMI, Auteur Année de publication : 2008 Article en page(s) : p.333-341 Langues : Anglais (eng) Mots-clés : Autism Tourette-Syndrome Autoantibody Glial-fibrillary-acidic-protein Immunoglobulin Index. décimale : PER Périodiques Résumé : Controversy exists over the role of autoantibodies to central nervous system antigens in autism and Tourette Syndrome. We investigated plasma autoantibody titers to glial fibrillary acidic protein (GFAP) in children with classic onset (33) and regressive onset (26) autism, controls (25, healthy age- and gender-matched) and individuals with Tourette Syndrome (24) by enzyme-linked immunosorbent assays. We found a significant difference in autoantibody titers to GFAP, not accounted for by age, between the Tourette (significantly lower) and regressive autism groups. However, no differences were found between: classic/regressive; classic/controls; classic/Tourette; regressive/controls; or controls/Tourette. Autoantibody responses against GFAP are unlikely to play a pathogenic role in autism or Tourette Syndrome. En ligne : http://dx.doi.org/10.1007/s10803-007-0398-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=318 [article] How Relevant are GFAP Autoantibodies in Autism and Tourette Syndrome? [Texte imprimé et/ou numérique] / Nikki J. KIRKMAN, Auteur ; William M. MCMAHON, Auteur ; Janet E. LAINHART, Auteur ; Jane E. LIBBEY, Auteur ; Hilary H. COON, Auteur ; Thayne L. SWEETEN, Auteur ; Judith N. MILLER, Auteur ; Edward K. STEVENSON, Auteur ; Robert S. FUJINAMI, Auteur . - 2008 . - p.333-341. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-2 (February 2008) . - p.333-341 Mots-clés : Autism Tourette-Syndrome Autoantibody Glial-fibrillary-acidic-protein Immunoglobulin Index. décimale : PER Périodiques Résumé : Controversy exists over the role of autoantibodies to central nervous system antigens in autism and Tourette Syndrome. We investigated plasma autoantibody titers to glial fibrillary acidic protein (GFAP) in children with classic onset (33) and regressive onset (26) autism, controls (25, healthy age- and gender-matched) and individuals with Tourette Syndrome (24) by enzyme-linked immunosorbent assays. We found a significant difference in autoantibody titers to GFAP, not accounted for by age, between the Tourette (significantly lower) and regressive autism groups. However, no differences were found between: classic/regressive; classic/controls; classic/Tourette; regressive/controls; or controls/Tourette. Autoantibody responses against GFAP are unlikely to play a pathogenic role in autism or Tourette Syndrome. En ligne : http://dx.doi.org/10.1007/s10803-007-0398-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=318

---

1 (1 - 2 / 2)