Dépouillements

Externalizing and internalizing behaviors in ASD / Nirit BAUMINGER in Autism Research, 3-3 (June 2010)  

Public ISBD [article]  inAutism Research > 3-3 (June 2010) . - p.101-112 Titre : Externalizing and internalizing behaviors in ASD Type de document : Texte imprimé et/ou numérique Auteurs : Nirit BAUMINGER, Auteur ; Marjorie SOLOMON, Auteur ; Sally J ROGERS, Auteur Année de publication : 2010 Article en page(s) : p.101-112 Langues : Anglais (eng) Mots-clés : psychopathology adaptive behavior high-functioning-ASD parental-stress Index. décimale : PER Périodiques Résumé : The current study investigated the relationships between internalizing and externalizing (I-E) behaviors and family variables, including both parenting stress and quality of attachment relations, in children aged 8-12 with high-functioning autism spectrum disorder (ASD) or with typical development. Compared to the group with typical development, children with ASD exhibited significantly greater levels of psychopathology as assessed by the Child Behavior Checklist [Achenbach, 1991], and parents of children with ASD exhibited higher parenting stress as assessed by the Parenting Stress Index [Abidin, 1995]. In a hierarchical multiple regression analysis, parenting stress emerged as the most important predictor of children's I-E problems. Results are discussed in light of the two groups' similar relationships between parenting stress and child psychopathology. En ligne : http://dx.doi.org/10.1002/aur.131 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107 [article] Externalizing and internalizing behaviors in ASD [Texte imprimé et/ou numérique] / Nirit BAUMINGER, Auteur ; Marjorie SOLOMON, Auteur ; Sally J ROGERS, Auteur . - 2010 . - p.101-112. Langues : Anglais (eng) in Autism Research > 3-3 (June 2010) . - p.101-112 Mots-clés : psychopathology adaptive behavior high-functioning-ASD parental-stress Index. décimale : PER Périodiques Résumé : The current study investigated the relationships between internalizing and externalizing (I-E) behaviors and family variables, including both parenting stress and quality of attachment relations, in children aged 8-12 with high-functioning autism spectrum disorder (ASD) or with typical development. Compared to the group with typical development, children with ASD exhibited significantly greater levels of psychopathology as assessed by the Child Behavior Checklist [Achenbach, 1991], and parents of children with ASD exhibited higher parenting stress as assessed by the Parenting Stress Index [Abidin, 1995]. In a hierarchical multiple regression analysis, parenting stress emerged as the most important predictor of children's I-E problems. Results are discussed in light of the two groups' similar relationships between parenting stress and child psychopathology. En ligne : http://dx.doi.org/10.1002/aur.131 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107

Susceptibility to the Shepard illusion in participants with autism: reduced top-down influences within perception? / Peter MITCHELL in Autism Research, 3-3 (June 2010)  

Public ISBD [article]  inAutism Research > 3-3 (June 2010) . - p.113-119 Titre : Susceptibility to the Shepard illusion in participants with autism: reduced top-down influences within perception? Type de document : Texte imprimé et/ou numérique Auteurs : Peter MITCHELL, Auteur ; Laurent MOTTRON, Auteur ; Danielle ROPAR, Auteur ; Isabelle SOULIERES, Auteur Année de publication : 2010 Article en page(s) : p.113-119 Langues : Anglais (eng) Mots-clés : low-level-perception visual-illusion 3D-perception Index. décimale : PER Périodiques Résumé : Previous research [Ropar & Mitchell, [2002]] has shown that autistic individuals are somewhat immune to biases induced by top-down processes, particularly the influence of previous knowledge on perception. In order to test this hypothesis within perception, 18 participants with autism who had measured intelligence in the normal range were compared against 18 matched controls in their susceptibility to the Shepard illusion. The illusion consists in misperceiving the shape of a parallelogram in the presence of depth cues. It is attributed [Mitchell, Ropar, Ackroyd, & Rajendran, [2005]] to the effect of top-down constraints within perception. The task involved adjusting a stimulus to the dimensions of a template on a computer screen. Both groups were susceptible to the illusion and the illusion effect was stronger when three-dimensional perspective cues were prominent. Notably, participants with autism were less susceptible to the illusion than typically developing individuals. The findings raise the possibility that in some instances top-down influences are attenuated in individuals with autism. En ligne : http://dx.doi.org/10.1002/aur.130 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107 [article] Susceptibility to the Shepard illusion in participants with autism: reduced top-down influences within perception? [Texte imprimé et/ou numérique] / Peter MITCHELL, Auteur ; Laurent MOTTRON, Auteur ; Danielle ROPAR, Auteur ; Isabelle SOULIERES, Auteur . - 2010 . - p.113-119. Langues : Anglais (eng) in Autism Research > 3-3 (June 2010) . - p.113-119 Mots-clés : low-level-perception visual-illusion 3D-perception Index. décimale : PER Périodiques Résumé : Previous research [Ropar & Mitchell, [2002]] has shown that autistic individuals are somewhat immune to biases induced by top-down processes, particularly the influence of previous knowledge on perception. In order to test this hypothesis within perception, 18 participants with autism who had measured intelligence in the normal range were compared against 18 matched controls in their susceptibility to the Shepard illusion. The illusion consists in misperceiving the shape of a parallelogram in the presence of depth cues. It is attributed [Mitchell, Ropar, Ackroyd, & Rajendran, [2005]] to the effect of top-down constraints within perception. The task involved adjusting a stimulus to the dimensions of a template on a computer screen. Both groups were susceptible to the illusion and the illusion effect was stronger when three-dimensional perspective cues were prominent. Notably, participants with autism were less susceptible to the illusion than typically developing individuals. The findings raise the possibility that in some instances top-down influences are attenuated in individuals with autism. En ligne : http://dx.doi.org/10.1002/aur.130 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107

Association between depression and anxiety in high-functioning children with autism spectrum disorders and maternal mood symptoms / Carla A. MAZEFSKY in Autism Research, 3-3 (June 2010)  

Public ISBD [article]  inAutism Research > 3-3 (June 2010) . - p.120-127 Titre : Association between depression and anxiety in high-functioning children with autism spectrum disorders and maternal mood symptoms Type de document : Texte imprimé et/ou numérique Auteurs : Carla A. MAZEFSKY, Auteur ; Donald P. OSWALD, Auteur ; Caitlin M. CONNER, Auteur Année de publication : 2010 Article en page(s) : p.120-127 Langues : Anglais (eng) Mots-clés : autism Asperger's-disorder psychiatric-comorbidity anxiety depression mood-disorders familial-aggregation maternal-symptoms Index. décimale : PER Périodiques Résumé : Research suggests that children with autism spectrum disorders (ASDs) and their relatives have high rates of depression and anxiety. However, relatively few studies have looked at both factors concurrently. This study examined the potential relationship between maternal mood symptoms and depression and anxiety in their children with ASD. Participants were 31 10- to 17-year-old children with an ASD diagnosis that was supported by gold-standard measures and their biological mothers. Mothers completed the Autism Comorbidity Interview to determine whether the child with ASD met criteria for any depressive or anxiety diagnoses and a questionnaire of their own current mood symptoms. As expected, many children with ASD met criteria for lifetime diagnoses of depressive (32%) and anxiety disorders (39%). Mothers' report of their own current mood symptoms revealed averages within the normal range, though there was significant variability. Approximately 75% of children with ASD could be correctly classified as having a depressive or anxiety disorder history or not based on maternal symptoms of interpersonal sensitivity, hostility, phobic anxiety, depression, and anxiety. The results provide preliminary evidence that maternal mood symptoms may be related to depression and anxiety in their children with ASD. Although the design did not allow for testing of heritability per se, the familial transmission patterns were generally consistent with research in typical populations. While larger follow-up studies are needed, this research has implications for prevention and intervention efforts. En ligne : http://dx.doi.org/10.1002/aur.133 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107 [article] Association between depression and anxiety in high-functioning children with autism spectrum disorders and maternal mood symptoms [Texte imprimé et/ou numérique] / Carla A. MAZEFSKY, Auteur ; Donald P. OSWALD, Auteur ; Caitlin M. CONNER, Auteur . - 2010 . - p.120-127. Langues : Anglais (eng) in Autism Research > 3-3 (June 2010) . - p.120-127 Mots-clés : autism Asperger's-disorder psychiatric-comorbidity anxiety depression mood-disorders familial-aggregation maternal-symptoms Index. décimale : PER Périodiques Résumé : Research suggests that children with autism spectrum disorders (ASDs) and their relatives have high rates of depression and anxiety. However, relatively few studies have looked at both factors concurrently. This study examined the potential relationship between maternal mood symptoms and depression and anxiety in their children with ASD. Participants were 31 10- to 17-year-old children with an ASD diagnosis that was supported by gold-standard measures and their biological mothers. Mothers completed the Autism Comorbidity Interview to determine whether the child with ASD met criteria for any depressive or anxiety diagnoses and a questionnaire of their own current mood symptoms. As expected, many children with ASD met criteria for lifetime diagnoses of depressive (32%) and anxiety disorders (39%). Mothers' report of their own current mood symptoms revealed averages within the normal range, though there was significant variability. Approximately 75% of children with ASD could be correctly classified as having a depressive or anxiety disorder history or not based on maternal symptoms of interpersonal sensitivity, hostility, phobic anxiety, depression, and anxiety. The results provide preliminary evidence that maternal mood symptoms may be related to depression and anxiety in their children with ASD. Although the design did not allow for testing of heritability per se, the familial transmission patterns were generally consistent with research in typical populations. While larger follow-up studies are needed, this research has implications for prevention and intervention efforts. En ligne : http://dx.doi.org/10.1002/aur.133 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107

Object-based attention benefits reveal selective abnormalities of visual integration in autism / Christine M. FALTER in Autism Research, 3-3 (June 2010)  

Public ISBD [article]  inAutism Research > 3-3 (June 2010) . - p.128-136 Titre : Object-based attention benefits reveal selective abnormalities of visual integration in autism Type de document : Texte imprimé et/ou numérique Auteurs : Christine M. FALTER, Auteur ; Greg DAVIS, Auteur ; Kate C. PLAISTED-GRANT, Auteur Année de publication : 2010 Article en page(s) : p.128-136 Langues : Anglais (eng) Mots-clés : autism Gestalt grouping top-down Index. décimale : PER Périodiques Résumé : A pervasive integration deficit could provide a powerful and elegant account of cognitive processing in autism spectrum disorders (ASD). However, in the case of visual Gestalt grouping, typically assessed by tasks that require participants explicitly to introspect on their own grouping perception, clear evidence for such a deficit remains elusive. To resolve this issue, we adopt an index of Gestalt grouping from the object-based attention literature that does not require participants to assess their own grouping perception. Children with ASD and mental- and chronological-age matched typically developing children (TD) performed speeded orientation discriminations of two diagonal lines. The lines were superimposed on circles that were either grouped together or segmented on the basis of color, proximity or these two dimensions in competition. The magnitude of performance benefits evident for grouped circles, relative to ungrouped circles, provided an index of grouping under various conditions. Children with ASD showed comparable grouping by proximity to the TD group, but reduced grouping by similarity. ASD seems characterized by a selective bias away from grouping by similarity combined with typical levels of grouping by proximity, rather than by a pervasive integration deficit. En ligne : http://dx.doi.org/10.1002/aur.134 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107 [article] Object-based attention benefits reveal selective abnormalities of visual integration in autism [Texte imprimé et/ou numérique] / Christine M. FALTER, Auteur ; Greg DAVIS, Auteur ; Kate C. PLAISTED-GRANT, Auteur . - 2010 . - p.128-136. Langues : Anglais (eng) in Autism Research > 3-3 (June 2010) . - p.128-136 Mots-clés : autism Gestalt grouping top-down Index. décimale : PER Périodiques Résumé : A pervasive integration deficit could provide a powerful and elegant account of cognitive processing in autism spectrum disorders (ASD). However, in the case of visual Gestalt grouping, typically assessed by tasks that require participants explicitly to introspect on their own grouping perception, clear evidence for such a deficit remains elusive. To resolve this issue, we adopt an index of Gestalt grouping from the object-based attention literature that does not require participants to assess their own grouping perception. Children with ASD and mental- and chronological-age matched typically developing children (TD) performed speeded orientation discriminations of two diagonal lines. The lines were superimposed on circles that were either grouped together or segmented on the basis of color, proximity or these two dimensions in competition. The magnitude of performance benefits evident for grouped circles, relative to ungrouped circles, provided an index of grouping under various conditions. Children with ASD showed comparable grouping by proximity to the TD group, but reduced grouping by similarity. ASD seems characterized by a selective bias away from grouping by similarity combined with typical levels of grouping by proximity, rather than by a pervasive integration deficit. En ligne : http://dx.doi.org/10.1002/aur.134 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107

Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly / Kim L. MCBRIDE in Autism Research, 3-3 (June 2010)  

Public ISBD [article]  inAutism Research > 3-3 (June 2010) . - p.137-141 Titre : Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly Type de document : Texte imprimé et/ou numérique Auteurs : Kim L. MCBRIDE, Auteur ; Elizabeth A. VARGA, Auteur ; Matthew T. PASTORE, Auteur ; Thomas W. PRIOR, Auteur ; Kandamurugu MANICKAM, Auteur ; Joan F. ATKIN, Auteur ; Gail E. HERMAN, Auteur Année de publication : 2010 Article en page(s) : p.137-141 Langues : Anglais (eng) Mots-clés : genetic Cowden-syndrome molecular-genetics PTEN cancer autism developmental-delay Index. décimale : PER Périodiques Résumé : There is a strong genetic component to autism spectrum disorders (ASD), but due to significant genetic heterogeneity, individual genetic abnormalities contribute a small percentage to the overall total. Previous studies have demonstrated PTEN mutations in a sizable proportion of individuals with ASD or mental retardation/developmental delays (MR/DD) and macrocephaly that do not have features of Cowden or Bannayan-Riley-Ruvalcaba syndrome. This study was performed to confirm our previous results. We reviewed the charts of individuals who had PTEN clinical sequencing performed at our institution from January 2008 to July 2009. There were 93 subjects tested from our institution during that period. PTEN mutations were found in 2/39 (5.1%) ASD patients and 2/51 (3.9%) MR/DD patients. Three additional patients without mutations had no diagnostic information. Multiple relatives of individuals with a PTEN mutation had macrocephaly, MR, or early onset cancer (breast, renal, and prostate). Of those relatives tested, all had the familial PTEN mutation. None of the affected relatives had previously been diagnosed with Cowden or Bannayan-Riley-Ruvalcaba syndrome. We noted in our previous study several adult relatives without any findings who carried a mutation. Combined with data from our previous cohort, we have found PTEN mutations in 7/99 (7.1%) of individuals with ASD and 8/100 (8.0%) of individuals with MR/DD, all of whom had macrocephaly. We recommend testing for mutations in PTEN for individuals with ASD or MR/DD and macrocephaly. If mutations are found, other family members should be offered testing and the adults offered cancer screening if they have a PTEN mutation. En ligne : http://dx.doi.org/10.1002/aur.132 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107 [article] Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly [Texte imprimé et/ou numérique] / Kim L. MCBRIDE, Auteur ; Elizabeth A. VARGA, Auteur ; Matthew T. PASTORE, Auteur ; Thomas W. PRIOR, Auteur ; Kandamurugu MANICKAM, Auteur ; Joan F. ATKIN, Auteur ; Gail E. HERMAN, Auteur . - 2010 . - p.137-141. Langues : Anglais (eng) in Autism Research > 3-3 (June 2010) . - p.137-141 Mots-clés : genetic Cowden-syndrome molecular-genetics PTEN cancer autism developmental-delay Index. décimale : PER Périodiques Résumé : There is a strong genetic component to autism spectrum disorders (ASD), but due to significant genetic heterogeneity, individual genetic abnormalities contribute a small percentage to the overall total. Previous studies have demonstrated PTEN mutations in a sizable proportion of individuals with ASD or mental retardation/developmental delays (MR/DD) and macrocephaly that do not have features of Cowden or Bannayan-Riley-Ruvalcaba syndrome. This study was performed to confirm our previous results. We reviewed the charts of individuals who had PTEN clinical sequencing performed at our institution from January 2008 to July 2009. There were 93 subjects tested from our institution during that period. PTEN mutations were found in 2/39 (5.1%) ASD patients and 2/51 (3.9%) MR/DD patients. Three additional patients without mutations had no diagnostic information. Multiple relatives of individuals with a PTEN mutation had macrocephaly, MR, or early onset cancer (breast, renal, and prostate). Of those relatives tested, all had the familial PTEN mutation. None of the affected relatives had previously been diagnosed with Cowden or Bannayan-Riley-Ruvalcaba syndrome. We noted in our previous study several adult relatives without any findings who carried a mutation. Combined with data from our previous cohort, we have found PTEN mutations in 7/99 (7.1%) of individuals with ASD and 8/100 (8.0%) of individuals with MR/DD, all of whom had macrocephaly. We recommend testing for mutations in PTEN for individuals with ASD or MR/DD and macrocephaly. If mutations are found, other family members should be offered testing and the adults offered cancer screening if they have a PTEN mutation. En ligne : http://dx.doi.org/10.1002/aur.132 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107

Clinical genetic microarray testing; ASD neuropathology / Edwin H. Jr COOK in Autism Research, 3-3 (June 2010)  

Public ISBD [article]  inAutism Research > 3-3 (June 2010) . - p.142-143 Titre : Clinical genetic microarray testing; ASD neuropathology Type de document : Texte imprimé et/ou numérique Auteurs : Edwin H. Jr COOK, Auteur Année de publication : 2010 Article en page(s) : p.142-143 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.140 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107 [article] Clinical genetic microarray testing; ASD neuropathology [Texte imprimé et/ou numérique] / Edwin H. Jr COOK, Auteur . - 2010 . - p.142-143. Langues : Anglais (eng) in Autism Research > 3-3 (June 2010) . - p.142-143 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.140 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107

Lay abstracts in Autism Research, 3-3 (June 2010)  

Public ISBD [article]  inAutism Research > 3-3 (June 2010) . - p.144-145 Titre : Lay abstracts Type de document : Texte imprimé et/ou numérique Année de publication : 2010 Article en page(s) : p.144-145 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.138 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107 [article] Lay abstracts [Texte imprimé et/ou numérique] . - 2010 . - p.144-145. Langues : Anglais (eng) in Autism Research > 3-3 (June 2010) . - p.144-145 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.138 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107

International Society for Autism Research News in Autism Research, 3-3 (June 2010)  

Public ISBD [article]  inAutism Research > 3-3 (June 2010) . - p.146 Titre : International Society for Autism Research News Type de document : Texte imprimé et/ou numérique Année de publication : 2010 Article en page(s) : p.146 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.139 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107 [article] International Society for Autism Research News [Texte imprimé et/ou numérique] . - 2010 . - p.146. Langues : Anglais (eng) in Autism Research > 3-3 (June 2010) . - p.146 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.139 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107