[article]
| Titre : |
The default mode network is associated with changes in internalizing and externalizing problems differently in adolescent boys and girls |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Rajpreet CHAHAL, Auteur ; Ian H. GOTLIB, Auteur |
| Article en page(s) : |
p.834-843 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
adolescence brain functional connectivity externalizing internalizing sex differences |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Internalizing and externalizing problems that emerge during adolescence differentially increase boys' and girls' risk for developing psychiatric disorders. It is not clear, however, whether there are sex differences in the intrinsic functional architecture of the brain that underlie changes in the severity of internalizing and externalizing problems in adolescents. Using resting-state fMRI data and self-reports of behavioral problems obtained from 128 adolescents (73 females; 9-14 years old) at two timepoints, we conducted multivoxel pattern analysis to identify resting-state functional connectivity markers at baseline that predict changes in the severity of internalizing and externalizing problems in boys and girls 2 years later. We found sex-differentiated involvement of the default mode network in changes in internalizing and externalizing problems. Whereas changes in internalizing problems were associated with the dorsal medial subsystem in boys and with the medial temporal subsystem in girls, changes in externalizing problems were predicted by hyperconnectivity between core nodes of the DMN and frontoparietal network in boys and hypoconnectivity between the DMN and affective networks in girls. Our results suggest that different neural mechanisms predict changes in internalizing and externalizing problems in adolescent boys and girls and offer insights concerning mechanisms that underlie sex differences in the expression of psychopathology in adolescence. |
| En ligne : |
https://dx.doi.org/10.1017/S0954579423000111 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=528 |
in Development and Psychopathology > 36-2 (May 2024) . - p.834-843
[article] The default mode network is associated with changes in internalizing and externalizing problems differently in adolescent boys and girls [Texte imprimé et/ou numérique] / Rajpreet CHAHAL, Auteur ; Ian H. GOTLIB, Auteur . - p.834-843. Langues : Anglais ( eng) in Development and Psychopathology > 36-2 (May 2024) . - p.834-843
| Mots-clés : |
adolescence brain functional connectivity externalizing internalizing sex differences |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Internalizing and externalizing problems that emerge during adolescence differentially increase boys' and girls' risk for developing psychiatric disorders. It is not clear, however, whether there are sex differences in the intrinsic functional architecture of the brain that underlie changes in the severity of internalizing and externalizing problems in adolescents. Using resting-state fMRI data and self-reports of behavioral problems obtained from 128 adolescents (73 females; 9-14 years old) at two timepoints, we conducted multivoxel pattern analysis to identify resting-state functional connectivity markers at baseline that predict changes in the severity of internalizing and externalizing problems in boys and girls 2 years later. We found sex-differentiated involvement of the default mode network in changes in internalizing and externalizing problems. Whereas changes in internalizing problems were associated with the dorsal medial subsystem in boys and with the medial temporal subsystem in girls, changes in externalizing problems were predicted by hyperconnectivity between core nodes of the DMN and frontoparietal network in boys and hypoconnectivity between the DMN and affective networks in girls. Our results suggest that different neural mechanisms predict changes in internalizing and externalizing problems in adolescent boys and girls and offer insights concerning mechanisms that underlie sex differences in the expression of psychopathology in adolescence. |
| En ligne : |
https://dx.doi.org/10.1017/S0954579423000111 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=528 |
|
The default mode network is associated with changes in internalizing and externalizing problems differently in adolescent boys and girls in Development and Psychopathology, 36-2 (May 2024)
