Autism Spectrum Symptomatology Among Children with Duplication 7q11.23 Syndrome / B. P. KLEIN-TASMAN in Journal of Autism and Developmental Disorders, 48-6 (June 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-6 (June 2018) . - p.1982-1994 Titre : Autism Spectrum Symptomatology Among Children with Duplication 7q11.23 Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : B. P. KLEIN-TASMAN, Auteur ; C. B. MERVIS, Auteur Article en page(s) : p.1982-1994 Langues : Anglais (eng) Mots-clés : 7q11.23 duplication syndrome  Autism spectrum disorders  Selective mutism  Social anxiety Index. décimale : PER Périodiques Résumé : Gold-standard diagnostic assessments of autism spectrum disorder (ASD) symptomatology were conducted on 63 children (mean CA: 8.81 years) with 7q11.23 duplication syndrome, one of the copy number variants identified by Sanders et al. (Neuron 70:863-885, 2011a) as associated with ASD. ASD classification rate was 39.6% for the Autism Diagnostic Interview-Revised and 25.4% for the Autism Diagnostic Observation Schedule-2 (ADOS-2). Based on these assessments combined with clinical judgment, 19.0% of children were diagnosed with ASD. Reasons for these discrepancies are discussed, as are differences in rate of diagnosis as a function of sex, age, and ADOS-2 module administered and differences in intellectual and adaptive behavior abilities as a function of presence or absence of ASD diagnosis and ADOS-2 module administered. Implications are addressed. En ligne : http://dx.doi.org/10.1007/s10803-017-3439-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=361 [article] Autism Spectrum Symptomatology Among Children with Duplication 7q11.23 Syndrome [Texte imprimé et/ou numérique] / B. P. KLEIN-TASMAN, Auteur ; C. B. MERVIS, Auteur . - p.1982-1994. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-6 (June 2018) . - p.1982-1994 Mots-clés : 7q11.23 duplication syndrome  Autism spectrum disorders  Selective mutism  Social anxiety Index. décimale : PER Périodiques Résumé : Gold-standard diagnostic assessments of autism spectrum disorder (ASD) symptomatology were conducted on 63 children (mean CA: 8.81 years) with 7q11.23 duplication syndrome, one of the copy number variants identified by Sanders et al. (Neuron 70:863-885, 2011a) as associated with ASD. ASD classification rate was 39.6% for the Autism Diagnostic Interview-Revised and 25.4% for the Autism Diagnostic Observation Schedule-2 (ADOS-2). Based on these assessments combined with clinical judgment, 19.0% of children were diagnosed with ASD. Reasons for these discrepancies are discussed, as are differences in rate of diagnosis as a function of sex, age, and ADOS-2 module administered and differences in intellectual and adaptive behavior abilities as a function of presence or absence of ASD diagnosis and ADOS-2 module administered. Implications are addressed. En ligne : http://dx.doi.org/10.1007/s10803-017-3439-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=361

Autism Spectrum Symptomatology in Children with Williams Syndrome Who Have Phrase Speech or Fluent Language / B. P. KLEIN-TASMAN in Journal of Autism and Developmental Disorders, 48-9 (September 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-9 (September 2018) . - p.3037-3050 Titre : Autism Spectrum Symptomatology in Children with Williams Syndrome Who Have Phrase Speech or Fluent Language Type de document : Texte imprimé et/ou numérique Auteurs : B. P. KLEIN-TASMAN, Auteur ; F. VAN DER FLUIT, Auteur ; C. B. MERVIS, Auteur Article en page(s) : p.3037-3050 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Intellectual disability  Social communication  Williams syndrome Index. décimale : PER Périodiques Résumé : To characterize autism spectrum-related symptomatology in children with Williams syndrome (WS) with phrase speech or fluent language, the Autism Diagnostic Observation Schedule Module 2 or 3 was administered. The cutoff for autism spectrum was met by 35% (14/40) who completed Module 2 and 30% (18/60) who completed Module 3. Similarities and differences in socio-communicative strengths and weaknesses as a function of language ability were identified. Symptom severity was negatively associated with IQ for participants with phrase speech but not for those with fluent language. The findings suggest an elevated risk of ASD for individuals with WS relative to the general population and contribute to a more nuanced sense of the socio-communicative functioning of children with WS. En ligne : http://dx.doi.org/10.1007/s10803-018-3555-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367 [article] Autism Spectrum Symptomatology in Children with Williams Syndrome Who Have Phrase Speech or Fluent Language [Texte imprimé et/ou numérique] / B. P. KLEIN-TASMAN, Auteur ; F. VAN DER FLUIT, Auteur ; C. B. MERVIS, Auteur . - p.3037-3050. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-9 (September 2018) . - p.3037-3050 Mots-clés : Autism spectrum disorders  Intellectual disability  Social communication  Williams syndrome Index. décimale : PER Périodiques Résumé : To characterize autism spectrum-related symptomatology in children with Williams syndrome (WS) with phrase speech or fluent language, the Autism Diagnostic Observation Schedule Module 2 or 3 was administered. The cutoff for autism spectrum was met by 35% (14/40) who completed Module 2 and 30% (18/60) who completed Module 3. Similarities and differences in socio-communicative strengths and weaknesses as a function of language ability were identified. Symptom severity was negatively associated with IQ for participants with phrase speech but not for those with fluent language. The findings suggest an elevated risk of ASD for individuals with WS relative to the general population and contribute to a more nuanced sense of the socio-communicative functioning of children with WS. En ligne : http://dx.doi.org/10.1007/s10803-018-3555-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367

---

1 (1 - 2 / 2)