Development of a patient-centered conceptual model of the impact of living with autism spectrum disorder / F. MCDOUGALL in Autism, 22-8 (November 2018)  

Public ISBD [article]  inAutism > 22-8 (November 2018) . - p.953-969 Titre : Development of a patient-centered conceptual model of the impact of living with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : F. MCDOUGALL, Auteur ; T. WILLGOSS, Auteur ; S. HWANG, Auteur ; Federico BOLOGNANI, Auteur ; L. MURTAGH, Auteur ; Evdokia ANAGNOSTOU, Auteur ; D. ROFAIL, Auteur Article en page(s) : p.953-969 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  conceptual model  qualitative research Index. décimale : PER Périodiques Résumé : The aim of this study was to generate a patient-centered conceptual model of the impact of living with autism spectrum disorder, which can be used to support the selection of outcome measures for clinical trials. Following an initial literature review to identify preliminary concepts and inform an interview guide, in-depth face-to-face interviews were conducted with adolescents and adults with autism spectrum disorder (IQ 70) (n = 10), as well as parents of children, adolescents, and adults with autism spectrum disorder (IQ 70) (n = 26). Data were analyzed using established qualitative research methods. The resultant conceptual model contains three interrelated domains reflecting core symptoms of autism spectrum disorder (communication deficits, socialization deficits, and restrictive, repetitive patterns of behavior), three domains reflecting associated symptoms of autism spectrum disorder (physical, cognitive, and emotional/behavioral), and three domains representing the impacts of living with autism spectrum disorder (impacts on activities of daily living, school/work, and social life). Interview respondents also cited social communication deficits as priority targets for new treatments. The conceptual model provides a patient-centered perspective of relevant concepts of autism spectrum disorder from the perspectives of people with autism spectrum disorder and their parents and offers a valuable tool for identifying valid patient-centered outcome measures for future clinical trials. En ligne : http://dx.doi.org/10.1177/1362361317718987 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370 [article] Development of a patient-centered conceptual model of the impact of living with autism spectrum disorder [Texte imprimé et/ou numérique] / F. MCDOUGALL, Auteur ; T. WILLGOSS, Auteur ; S. HWANG, Auteur ; Federico BOLOGNANI, Auteur ; L. MURTAGH, Auteur ; Evdokia ANAGNOSTOU, Auteur ; D. ROFAIL, Auteur . - p.953-969. Langues : Anglais (eng) in Autism > 22-8 (November 2018) . - p.953-969 Mots-clés : autism spectrum disorder  conceptual model  qualitative research Index. décimale : PER Périodiques Résumé : The aim of this study was to generate a patient-centered conceptual model of the impact of living with autism spectrum disorder, which can be used to support the selection of outcome measures for clinical trials. Following an initial literature review to identify preliminary concepts and inform an interview guide, in-depth face-to-face interviews were conducted with adolescents and adults with autism spectrum disorder (IQ 70) (n = 10), as well as parents of children, adolescents, and adults with autism spectrum disorder (IQ 70) (n = 26). Data were analyzed using established qualitative research methods. The resultant conceptual model contains three interrelated domains reflecting core symptoms of autism spectrum disorder (communication deficits, socialization deficits, and restrictive, repetitive patterns of behavior), three domains reflecting associated symptoms of autism spectrum disorder (physical, cognitive, and emotional/behavioral), and three domains representing the impacts of living with autism spectrum disorder (impacts on activities of daily living, school/work, and social life). Interview respondents also cited social communication deficits as priority targets for new treatments. The conceptual model provides a patient-centered perspective of relevant concepts of autism spectrum disorder from the perspectives of people with autism spectrum disorder and their parents and offers a valuable tool for identifying valid patient-centered outcome measures for future clinical trials. En ligne : http://dx.doi.org/10.1177/1362361317718987 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370

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