Harshness and unpredictability: Childhood environmental links with immune and asthma outcomes / Phoebe H. LAM in Development and Psychopathology, 34-2 (May 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-2 (May 2022) . - 587-596 Titre : Harshness and unpredictability: Childhood environmental links with immune and asthma outcomes Type de document : Texte imprimé et/ou numérique Auteurs : Phoebe H. LAM, Auteur ; Gregory E. MILLER, Auteur ; Lauren HOFFER, Auteur ; Rebekah SILIEZAR, Auteur ; Johanna DEZIL, Auteur ; Amanda MCDONALD, Auteur ; Edith CHEN, Auteur Article en page(s) : 587-596 Langues : Anglais (eng) Mots-clés : asthma  harshness  inflammation  unpredictability Index. décimale : PER Périodiques Résumé : The environment has pervasive impacts on human development, and two key environmental conditions ? harshness and unpredictability ? are proposed to be instrumental in tuning development. This study examined (1) how harsh and unpredictable environments related to immune and clinical outcomes in the context of childhood asthma, and (2) whether there were independent associations of harshness and unpredictability with these outcomes. Participants were 290 youth physician-diagnosed with asthma. Harshness was assessed with youth-reported exposure to violence and neighborhood-level murder rate. Unpredictability was assessed with parent reports of family structural changes. Youth also completed measures of asthma control as well as asthma quality of life and provided blood samples to assess immune profiles, including in vitro cytokine responses to challenge and sensitivity to inhibitory signals from glucocorticoids. Results indicated that harshness was associated with more pronounced pro-inflammatory cytokine production following challenge and less sensitivity to the inhibitory properties of glucocorticoids. Furthermore, youth exposed to harsher environments reported less asthma control and poorer quality of life. All associations with harshness persisted when controlling for unpredictability. No associations between unpredictability and outcomes were found. These findings suggest that relative to unpredictability, harshness may be a more consistent correlate of asthma-relevant immune and clinical outcomes. En ligne : http://dx.doi.org/10.1017/s0954579421001577 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Harshness and unpredictability: Childhood environmental links with immune and asthma outcomes [Texte imprimé et/ou numérique] / Phoebe H. LAM, Auteur ; Gregory E. MILLER, Auteur ; Lauren HOFFER, Auteur ; Rebekah SILIEZAR, Auteur ; Johanna DEZIL, Auteur ; Amanda MCDONALD, Auteur ; Edith CHEN, Auteur . - 587-596. Langues : Anglais (eng) in Development and Psychopathology > 34-2 (May 2022) . - 587-596 Mots-clés : asthma  harshness  inflammation  unpredictability Index. décimale : PER Périodiques Résumé : The environment has pervasive impacts on human development, and two key environmental conditions ? harshness and unpredictability ? are proposed to be instrumental in tuning development. This study examined (1) how harsh and unpredictable environments related to immune and clinical outcomes in the context of childhood asthma, and (2) whether there were independent associations of harshness and unpredictability with these outcomes. Participants were 290 youth physician-diagnosed with asthma. Harshness was assessed with youth-reported exposure to violence and neighborhood-level murder rate. Unpredictability was assessed with parent reports of family structural changes. Youth also completed measures of asthma control as well as asthma quality of life and provided blood samples to assess immune profiles, including in vitro cytokine responses to challenge and sensitivity to inhibitory signals from glucocorticoids. Results indicated that harshness was associated with more pronounced pro-inflammatory cytokine production following challenge and less sensitivity to the inhibitory properties of glucocorticoids. Furthermore, youth exposed to harsher environments reported less asthma control and poorer quality of life. All associations with harshness persisted when controlling for unpredictability. No associations between unpredictability and outcomes were found. These findings suggest that relative to unpredictability, harshness may be a more consistent correlate of asthma-relevant immune and clinical outcomes. En ligne : http://dx.doi.org/10.1017/s0954579421001577 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

One size does not fit all: Links between shift-and-persist and asthma in youth are moderated by perceived social status and experience of unfair treatment / Phoebe H. LAM in Development and Psychopathology, 30-5 (December 2018)  

Public ISBD [article]  inDevelopment and Psychopathology > 30-5 (December 2018) . - p.1699-1714 Titre : One size does not fit all: Links between shift-and-persist and asthma in youth are moderated by perceived social status and experience of unfair treatment Type de document : Texte imprimé et/ou numérique Auteurs : Phoebe H. LAM, Auteur ; Gregory E. MILLER, Auteur ; Jessica J. CHIANG, Auteur ; Cynthia S. LEVINE, Auteur ; Van LE, Auteur ; Madeleine U. SHALOWITZ, Auteur ; Rachel E. STORY, Auteur ; Edith CHEN, Auteur Article en page(s) : p.1699-1714 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The links between low socioeconomic status and poor health are well established, yet despite adversity, some individuals with low socioeconomic status appear to avoid these negative consequences through adaptive coping. Previous research found a set of strategies, called shift-and-persist (shifting the self to stressors while persisting by finding meaning), to be particularly adaptive for individuals with low socioeconomic status, who typically face more uncontrollable stressors. This study tested (a) whether perceived social status, similar to objective socioeconomic status, would moderate the link between shift-and-persist and health, and (b) whether a specific uncontrollable stressor, unfair treatment, would similarly moderate the health correlates of shift-and-persist. A sample of 308 youth (Meanage = 13.0, range 8–17), physician diagnosed with asthma, completed measures of shift-and-persist, unfair treatment, asthma control, and quality of life in the lab, and 2 weeks of daily diaries about their asthma symptoms. Parents reported on perceived family social status. Results indicated that shift-and-persist was associated with better asthma profiles, only among youth from families with lower (vs. higher) parent-reported perceived social status. Shift-and-persist was also associated with better asthma profiles, only among youth who experienced more (vs. less) unfair treatment. These findings suggest that the adaptive values of coping strategies for youth with asthma depend on the family's perceived social status and on the stressor experienced. En ligne : http://dx.doi.org/10.1017/S0954579418000913 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370 [article] One size does not fit all: Links between shift-and-persist and asthma in youth are moderated by perceived social status and experience of unfair treatment [Texte imprimé et/ou numérique] / Phoebe H. LAM, Auteur ; Gregory E. MILLER, Auteur ; Jessica J. CHIANG, Auteur ; Cynthia S. LEVINE, Auteur ; Van LE, Auteur ; Madeleine U. SHALOWITZ, Auteur ; Rachel E. STORY, Auteur ; Edith CHEN, Auteur . - p.1699-1714. Langues : Anglais (eng) in Development and Psychopathology > 30-5 (December 2018) . - p.1699-1714 Index. décimale : PER Périodiques Résumé : The links between low socioeconomic status and poor health are well established, yet despite adversity, some individuals with low socioeconomic status appear to avoid these negative consequences through adaptive coping. Previous research found a set of strategies, called shift-and-persist (shifting the self to stressors while persisting by finding meaning), to be particularly adaptive for individuals with low socioeconomic status, who typically face more uncontrollable stressors. This study tested (a) whether perceived social status, similar to objective socioeconomic status, would moderate the link between shift-and-persist and health, and (b) whether a specific uncontrollable stressor, unfair treatment, would similarly moderate the health correlates of shift-and-persist. A sample of 308 youth (Meanage = 13.0, range 8–17), physician diagnosed with asthma, completed measures of shift-and-persist, unfair treatment, asthma control, and quality of life in the lab, and 2 weeks of daily diaries about their asthma symptoms. Parents reported on perceived family social status. Results indicated that shift-and-persist was associated with better asthma profiles, only among youth from families with lower (vs. higher) parent-reported perceived social status. Shift-and-persist was also associated with better asthma profiles, only among youth who experienced more (vs. less) unfair treatment. These findings suggest that the adaptive values of coping strategies for youth with asthma depend on the family's perceived social status and on the stressor experienced. En ligne : http://dx.doi.org/10.1017/S0954579418000913 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370

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