[article]
| Titre : |
Beyond Gaze: Affective Synchrony and Sensory-Linked Interactional Profiles as Early Markers of Autism Risk |
| Type de document : |
texte imprimé |
| Auteurs : |
Lan LIN, Auteur ; Qian LI, Auteur ; Zenghe YUE, Auteur ; Yaxin DAI, Auteur ; Haozhen CHEN, Auteur ; Yuheng CHEN, Auteur ; Jinyi ZHU, Auteur ; Yazhu HAN, Auteur ; Shengjian YIN, Auteur ; Luyang GUAN, Auteur ; Xiaoyan KE, Auteur |
| Article en page(s) : |
e70209 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
autism spectrum disorder early identification high-risk infants interpersonal affect synchrony mutual gaze parent–child interaction sensory processing |
| Index. décimale : |
PER Périodiques |
| Résumé : |
ABSTRACT Identifying early markers for autism spectrum disorder (ASD) is a clinical priority. This study investigated interpersonal affect synchrony (IAS) as a measure of interactional quality in a longitudinal cohort of 90 high-risk infants. We aimed to disentangle its contribution from mutual gaze and identify data-driven social interaction profiles linked to sensory traits. Parent-infant interactions were recorded at 6?18?months; IAS was quantified using Cross-Recurrence Quantification Analysis, and ASD outcomes were determined at 18?24?months. Infants later diagnosed with ASD (n?=?25) showed significantly lower IAS (F(1,84)?=?5.89, p FDR?=?0.023) and synchrony stability (F(1,84)?=?5.37, p FDR?=?0.023) than non-diagnosed infants (n?=?65), yet the groups did not differ in mutual gaze (p?=?0.200). Logistic regression analysis further showed that IAS (OR?=?0.561, p FDR?=?0.038) and synchrony stability (OR?=?0.013, p FDR?=?0.038) both significantly predict clinical outcome. K-means clustering revealed three profiles: ?High Gaze-High Synchrony,? ?Mid Gaze-Low Synchrony,? and ?Low Gaze-High Synchrony.? The ?Mid Gaze-Low Synchrony? profile was significantly associated with a later ASD diagnosis (p adj?=?0.031), while the ?Low Gaze-High Synchrony? profile was linked to higher sensation-seeking traits (p adj?=?0.028). The quality of parent-infant affective connection is a more robust early marker for ASD than the quantity of mutual gaze. These findings reveal critical heterogeneity, identifying a high-risk ?gaze without engagement? pattern and a potential adaptive pathway to synchrony, underscoring the need for individualized strategies in early screening and intervention. |
| En ligne : |
https://doi.org/10.1002/aur.70209 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=585 |
in Autism Research > 19-4 (April 2026) . - e70209
[article] Beyond Gaze: Affective Synchrony and Sensory-Linked Interactional Profiles as Early Markers of Autism Risk [texte imprimé] / Lan LIN, Auteur ; Qian LI, Auteur ; Zenghe YUE, Auteur ; Yaxin DAI, Auteur ; Haozhen CHEN, Auteur ; Yuheng CHEN, Auteur ; Jinyi ZHU, Auteur ; Yazhu HAN, Auteur ; Shengjian YIN, Auteur ; Luyang GUAN, Auteur ; Xiaoyan KE, Auteur . - e70209. Langues : Anglais ( eng) in Autism Research > 19-4 (April 2026) . - e70209
| Mots-clés : |
autism spectrum disorder early identification high-risk infants interpersonal affect synchrony mutual gaze parent–child interaction sensory processing |
| Index. décimale : |
PER Périodiques |
| Résumé : |
ABSTRACT Identifying early markers for autism spectrum disorder (ASD) is a clinical priority. This study investigated interpersonal affect synchrony (IAS) as a measure of interactional quality in a longitudinal cohort of 90 high-risk infants. We aimed to disentangle its contribution from mutual gaze and identify data-driven social interaction profiles linked to sensory traits. Parent-infant interactions were recorded at 6?18?months; IAS was quantified using Cross-Recurrence Quantification Analysis, and ASD outcomes were determined at 18?24?months. Infants later diagnosed with ASD (n?=?25) showed significantly lower IAS (F(1,84)?=?5.89, p FDR?=?0.023) and synchrony stability (F(1,84)?=?5.37, p FDR?=?0.023) than non-diagnosed infants (n?=?65), yet the groups did not differ in mutual gaze (p?=?0.200). Logistic regression analysis further showed that IAS (OR?=?0.561, p FDR?=?0.038) and synchrony stability (OR?=?0.013, p FDR?=?0.038) both significantly predict clinical outcome. K-means clustering revealed three profiles: ?High Gaze-High Synchrony,? ?Mid Gaze-Low Synchrony,? and ?Low Gaze-High Synchrony.? The ?Mid Gaze-Low Synchrony? profile was significantly associated with a later ASD diagnosis (p adj?=?0.031), while the ?Low Gaze-High Synchrony? profile was linked to higher sensation-seeking traits (p adj?=?0.028). The quality of parent-infant affective connection is a more robust early marker for ASD than the quantity of mutual gaze. These findings reveal critical heterogeneity, identifying a high-risk ?gaze without engagement? pattern and a potential adaptive pathway to synchrony, underscoring the need for individualized strategies in early screening and intervention. |
| En ligne : |
https://doi.org/10.1002/aur.70209 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=585 |
|  |
Beyond Gaze: Affective Synchrony and Sensory-Linked Interactional Profiles as Early Markers of Autism Risk in Autism Research, 19-4 (April 2026)
