[article]
| Titre : |
Outcome and cost-effectiveness of transdiagnostic cognitive behavioral therapy compared with management as usual for youth with common mental health problems: Long-term results from the Mind-My-Mind randomized trial |
| Type de document : |
texte imprimé |
| Auteurs : |
Ditte VASSARD, Auteur ; Martin Køster RIMVALL, Auteur ; Rasmus Trap WOLF, Auteur ; Robin CHRISTENSEN, Auteur ; Sabrina M. NIELSEN, Auteur ; Kerstin Jessica PLESSEN, Auteur ; Frank VERHULST, Auteur ; Niels BILENBERG, Auteur ; Per Hove THOMSEN, Auteur ; Mikael THASTUM, Auteur ; Simon-Peter NEUMER, Auteur ; Anne Katrine PAGSBERG, Auteur ; Wendy K. SILVERMAN, Auteur ; Christoph U. CORRELL, Auteur ; Pia JEPPESEN, Auteur |
| Article en page(s) : |
p.1307-1320 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Cognitive behavioral therapy mental health problems school-based children and adolescents |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Background Credible long-term outcomes from randomized trials evaluating the effectiveness and cost-effectiveness of preventive programs for mental health problems are needed. We compared long-term effects of the Mind My Mind (MMM) transdiagnostic cognitive behavioral therapy (CBT) program to management as usual (MAU). Methods The study was a pragmatic, multisite, randomized superiority trial (2017?2019) involving youths aged 6?16?years with anxiety, depressive symptoms, and/or behavioral disturbances, recruited through family self-referral. The MMM intervention included 9?13 weekly CBT sessions. The primary outcome was change from baseline in parent-reported impact of mental health problems at 3-year follow-up post-randomization using the Strengths and Difficulties Questionnaire (SDQ) impact scale. Register-based outcomes tracked youths' psychiatric diagnoses in mental health services. To assess cost-effectiveness, we calculated the incremental costs and incremental quality-adjusted life years (QALYs). All primary analyses followed the intention-to-treat (ITT) approach. Clinical trials registration: ID NCT04804917. Results Among 396 youths randomized (baseline mean [SD] age, 10.3?[2.4] years; 52.0% boys; MMM n?=?197, MAU n?=?199), the 3-year follow-up (median 167?weeks; range 124?203?weeks) primary outcome data were available in 69.0% and 59.3%, respectively. The decrease in SDQ-impact-score from baseline to 3-year follow-up (4.12?1.79 points [MMM] and 4.21?1.85 [MAU]) was similar (between-group difference, 0.06 [95% CI ?0.41 to 0.52]; p?=?.81). An equal proportion (25%) of youths in MMM and MAU were diagnosed with any mental disorder during follow-up (HR 1.01, 95% CI 0.68?1.50). Total costs over the intervention period were higher in the MMM group (incremental costs 3,014 Euros [95% CI: 2.174?3.855]). Cost-effectiveness analyses favored MMM: QALY net gain 0.121 (95% CI 0.045?0.196); the cost-effectiveness ratio was 24,789 Euro/QALY. Conclusions Although MMM was potentially cost-effective, the beneficial effects diminished over 3?years post-treatment. The findings highlight the need for strategies to sustain long-term effects. |
| En ligne : |
https://doi.org/10.1111/jcpp.70128 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 |
in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1307-1320
[article] Outcome and cost-effectiveness of transdiagnostic cognitive behavioral therapy compared with management as usual for youth with common mental health problems: Long-term results from the Mind-My-Mind randomized trial [texte imprimé] / Ditte VASSARD, Auteur ; Martin Køster RIMVALL, Auteur ; Rasmus Trap WOLF, Auteur ; Robin CHRISTENSEN, Auteur ; Sabrina M. NIELSEN, Auteur ; Kerstin Jessica PLESSEN, Auteur ; Frank VERHULST, Auteur ; Niels BILENBERG, Auteur ; Per Hove THOMSEN, Auteur ; Mikael THASTUM, Auteur ; Simon-Peter NEUMER, Auteur ; Anne Katrine PAGSBERG, Auteur ; Wendy K. SILVERMAN, Auteur ; Christoph U. CORRELL, Auteur ; Pia JEPPESEN, Auteur . - p.1307-1320. Langues : Anglais ( eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1307-1320
| Mots-clés : |
Cognitive behavioral therapy mental health problems school-based children and adolescents |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Background Credible long-term outcomes from randomized trials evaluating the effectiveness and cost-effectiveness of preventive programs for mental health problems are needed. We compared long-term effects of the Mind My Mind (MMM) transdiagnostic cognitive behavioral therapy (CBT) program to management as usual (MAU). Methods The study was a pragmatic, multisite, randomized superiority trial (2017?2019) involving youths aged 6?16?years with anxiety, depressive symptoms, and/or behavioral disturbances, recruited through family self-referral. The MMM intervention included 9?13 weekly CBT sessions. The primary outcome was change from baseline in parent-reported impact of mental health problems at 3-year follow-up post-randomization using the Strengths and Difficulties Questionnaire (SDQ) impact scale. Register-based outcomes tracked youths' psychiatric diagnoses in mental health services. To assess cost-effectiveness, we calculated the incremental costs and incremental quality-adjusted life years (QALYs). All primary analyses followed the intention-to-treat (ITT) approach. Clinical trials registration: ID NCT04804917. Results Among 396 youths randomized (baseline mean [SD] age, 10.3?[2.4] years; 52.0% boys; MMM n?=?197, MAU n?=?199), the 3-year follow-up (median 167?weeks; range 124?203?weeks) primary outcome data were available in 69.0% and 59.3%, respectively. The decrease in SDQ-impact-score from baseline to 3-year follow-up (4.12?1.79 points [MMM] and 4.21?1.85 [MAU]) was similar (between-group difference, 0.06 [95% CI ?0.41 to 0.52]; p?=?.81). An equal proportion (25%) of youths in MMM and MAU were diagnosed with any mental disorder during follow-up (HR 1.01, 95% CI 0.68?1.50). Total costs over the intervention period were higher in the MMM group (incremental costs 3,014 Euros [95% CI: 2.174?3.855]). Cost-effectiveness analyses favored MMM: QALY net gain 0.121 (95% CI 0.045?0.196); the cost-effectiveness ratio was 24,789 Euro/QALY. Conclusions Although MMM was potentially cost-effective, the beneficial effects diminished over 3?years post-treatment. The findings highlight the need for strategies to sustain long-term effects. |
| En ligne : |
https://doi.org/10.1111/jcpp.70128 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 |
|  |
Outcome and cost-effectiveness of transdiagnostic cognitive behavioral therapy compared with management as usual for youth with common mental health problems: Long-term results from the Mind-My-Mind randomized trial in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)
