Relationship of family history conditions and early signs of autism spectrum disorder in low and high-risk infants / Maurice A. FELDMAN in Research in Autism Spectrum Disorders, 65 (September 2019)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 65 (September 2019) . - p.25-33 Titre : Relationship of family history conditions and early signs of autism spectrum disorder in low and high-risk infants Type de document : Texte imprimé et/ou numérique Auteurs : Maurice A. FELDMAN, Auteur ; Alicia AZZANO, Auteur ; Rebecca A. WARD, Auteur ; Melissa HUDSON, Auteur ; Calvin P. SJAARDA, Auteur ; Xudong LIU, Auteur Article en page(s) : p.25-33 Langues : Anglais (eng) Mots-clés : Infants  Siblings  Family history  Prediction  Early screening Index. décimale : PER Périodiques Résumé : Background Early identification and understanding of Autism Spectrum Disorder (ASD) could be facilitated by knowledge of family history of medical, developmental and psychiatric conditions associated with showing early signs of ASD. Method The current study used nonparametric analysis of covariance to compare the number of family history conditions n 69 high-risk (biological sibling with ASD) and 108 low-risk (no family history of ASD) infants. Spearman correlation was used to assess the relationship between family history of various conditions and early ASD signs as measured by an early screener, the Parent Observation of Early Markers Scale (POEMS). Results There were significantly more family history conditions in the families of the high-risk infants, and significant positive relationships between the number of family history problems and early markers of ASD in both groups. Conclusions The results suggest that family history conditions may play an important role in screening infants not yet diagnosed with ASD and reveal etiological pathways. En ligne : https://doi.org/10.1016/j.rasd.2019.05.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=401 [article] Relationship of family history conditions and early signs of autism spectrum disorder in low and high-risk infants [Texte imprimé et/ou numérique] / Maurice A. FELDMAN, Auteur ; Alicia AZZANO, Auteur ; Rebecca A. WARD, Auteur ; Melissa HUDSON, Auteur ; Calvin P. SJAARDA, Auteur ; Xudong LIU, Auteur . - p.25-33. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 65 (September 2019) . - p.25-33 Mots-clés : Infants  Siblings  Family history  Prediction  Early screening Index. décimale : PER Périodiques Résumé : Background Early identification and understanding of Autism Spectrum Disorder (ASD) could be facilitated by knowledge of family history of medical, developmental and psychiatric conditions associated with showing early signs of ASD. Method The current study used nonparametric analysis of covariance to compare the number of family history conditions n 69 high-risk (biological sibling with ASD) and 108 low-risk (no family history of ASD) infants. Spearman correlation was used to assess the relationship between family history of various conditions and early ASD signs as measured by an early screener, the Parent Observation of Early Markers Scale (POEMS). Results There were significantly more family history conditions in the families of the high-risk infants, and significant positive relationships between the number of family history problems and early markers of ASD in both groups. Conclusions The results suggest that family history conditions may play an important role in screening infants not yet diagnosed with ASD and reveal etiological pathways. En ligne : https://doi.org/10.1016/j.rasd.2019.05.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=401

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