Early Life Exposure to Antibiotics and Autism Spectrum Disorders: A Systematic Review / J. LUKASIK in Journal of Autism and Developmental Disorders, 49-9 (September 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-9 (September 2019) . - p.3866-3876 Titre : Early Life Exposure to Antibiotics and Autism Spectrum Disorders: A Systematic Review Type de document : texte imprimé Auteurs : J. LUKASIK, Auteur ; B. PATRO-GOLAB, Auteur ; A. HORVATH, Auteur ; R. BARON, Auteur ; H. SZAJEWSKA, Auteur Article en page(s) : p.3866-3876 Langues : Anglais (eng) Mots-clés : Antibiotics  Autism  Early life  Risk factors Index. décimale : PER Périodiques Résumé : We systematically reviewed evidence from observational studies on the associations between autism spectrum disorders (ASD) and early-life antibiotic exposure. Eleven articles were included in the review. Prenatal antibiotic exposure was associated with a slightly increased risk of ASD in two cohort studies on overlapping populations and in one case-control study; in three other case-control studies, no significant association was found. One cohort study found a slightly reduced risk of ASD after postnatal antibiotic exposure, while two other cohort studies on overlapping populations and three case-control studies reported an increased risk. Meta-analysis of the eligible studies showed no significant associations. Current data are conflicting and do not conclusively support the hypothesis that early-life antibiotic exposure is associated with subsequent ASD development. En ligne : http://dx.doi.org/10.1007/s10803-019-04093-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405 [article] Early Life Exposure to Antibiotics and Autism Spectrum Disorders: A Systematic Review [texte imprimé] / J. LUKASIK, Auteur ; B. PATRO-GOLAB, Auteur ; A. HORVATH, Auteur ; R. BARON, Auteur ; H. SZAJEWSKA, Auteur . - p.3866-3876. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-9 (September 2019) . - p.3866-3876 Mots-clés : Antibiotics  Autism  Early life  Risk factors Index. décimale : PER Périodiques Résumé : We systematically reviewed evidence from observational studies on the associations between autism spectrum disorders (ASD) and early-life antibiotic exposure. Eleven articles were included in the review. Prenatal antibiotic exposure was associated with a slightly increased risk of ASD in two cohort studies on overlapping populations and in one case-control study; in three other case-control studies, no significant association was found. One cohort study found a slightly reduced risk of ASD after postnatal antibiotic exposure, while two other cohort studies on overlapping populations and three case-control studies reported an increased risk. Meta-analysis of the eligible studies showed no significant associations. Current data are conflicting and do not conclusively support the hypothesis that early-life antibiotic exposure is associated with subsequent ASD development. En ligne : http://dx.doi.org/10.1007/s10803-019-04093-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405

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